| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takayuki Yoshida, Masanobu Kano, Masahiko Watanabe, Mitsuhiro Yoshiok. [The interaction between serotonergic and cannabinoidergic modulations involved in the fear extinction]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 33. issue 3. 2014-09-25. PMID:25069241. |
these findings suggest that endocannabinoid is synthesized via activation of postsynaptic 5-ht(2a) receptors, and regulates not only inhibitory presynaptic gaba release but also local serotonergic transmission in the ba. |
2014-09-25 |
2023-08-13 |
Not clear |
| Rammohan Shukla, Akiya Watakabe, Tetsuo Yamamor. mRNA expression profile of serotonin receptor subtypes and distribution of serotonergic terminations in marmoset brain. Frontiers in neural circuits. vol 8. 2014-09-24. PMID:24904298. |
to better understand serotonin function in the primate brain, we examined the mrna expression patterns of all the 13 members of the serotonin receptor (5htr) family, by in situ hybridization (ish) and the distribution of serotonergic terminations by serotonin transporter (sert) protein immunohistochemical analysis. |
2014-09-24 |
2023-08-13 |
mouse |
| Veronika Kiryanova, Brendan B McAllister, Richard H Dyc. Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature. Developmental neuroscience. vol 35. issue 6. 2014-09-22. PMID:24247012. |
an estimated 1.4-2.1% of pregnant women use this medication, which inhibits the reuptake of serotonin and thereby increases serotonergic activity at the synapse. |
2014-09-22 |
2023-08-12 |
Not clear |
| Georg S Kranz, Andreas Hahn, Pia Baldinger, Daniela Haeusler, Cecile Philippe, Ulrike Kaufmann, Wolfgang Wadsak, Markus Savli, Anna Hoeflich, Christoph Kraus, Thomas Vanicek, Markus Mitterhauser, Siegfried Kasper, Rupert Lanzenberge. Cerebral serotonin transporter asymmetry in females, males and male-to-female transsexuals measured by PET in vivo. Brain structure & function. vol 219. issue 1. 2014-09-19. PMID:23224294. |
the present data support the notion of a lateralized serotonergic system, which is in line with previous findings of asymmetric serotonin-1a receptor distributions, extracellular serotonin concentrations, serotonin turnover and uptake. |
2014-09-19 |
2023-08-12 |
Not clear |
| D Keszthelyi, F J Troost, D M Jonkers, H M van Eijk, P J Lindsey, J Dekker, W A Buurman, A A M Mascle. Serotonergic reinforcement of intestinal barrier function is impaired in irritable bowel syndrome. Alimentary pharmacology & therapeutics. vol 40. issue 4. 2014-09-18. PMID:24943480. |
alterations in serotonergic (5-ht) metabolism and/or intestinal integrity have been associated with irritable bowel syndrome (ibs). |
2014-09-18 |
2023-08-13 |
Not clear |
| Muhammad Farhan, Huma Ikram, Sumera Kanwal, Darakhshan Jabeen Halee. Unpredictable chronic mild stress induced behavioral deficits: a comparative study in male and female rats. Pakistan journal of pharmaceutical sciences. vol 27. issue 4. 2014-09-18. PMID:25015455. |
unpredictable chronic mild stress (ucms) also produces alteration in the serotonergic (5-ht; 5-hydroxytryptamine) neurotransmission. |
2014-09-18 |
2023-08-13 |
rat |
| Jan Kalbitzer, Urs Kalbitzer, Gitte Moos Knudsen, Paul Cumming, Andreas Hein. How the cerebral serotonin homeostasis predicts environmental changes: a model to explain seasonal changes of brain 5-HTT as intermediate phenotype of the 5-HTTLPR. Psychopharmacology. vol 230. issue 3. 2014-09-15. PMID:24150247. |
we argue that long-lasting fluctuations in the cerebral serotonin transmission, which is regulated via the 5-htt, are responsible for mediating responses to environmental changes based on an assessment of the expected "safety" of the environment; this response is obtained in part through serotonergic modulation of the hypothalamic-pituitary-adrenal (hpa) axis. |
2014-09-15 |
2023-08-12 |
human |
| Susie H Park, Robin C Wackernah, Glen L Stimme. Serotonin syndrome: is it a reason to avoid the use of tramadol with antidepressants? Journal of pharmacy practice. vol 27. issue 1. 2014-09-15. PMID:24153222. |
there is a warning associated with all serotonergic antidepressants and its concomitant use with tramadol due to the concern for a drug-drug interaction resulting in serotonin syndrome (ss). |
2014-09-15 |
2023-08-12 |
Not clear |
| Lucia Ciranna, Maria Vincenza Catani. 5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders. Frontiers in cellular neuroscience. vol 8. 2014-09-15. PMID:25221471. |
several abnormalities of serotonergic system have been described in patients with autism spectrum disorder (asd), including abnormal activity of 5-ht transporter, altered blood and brain 5-ht levels, reduced 5-ht synthesis and altered expression of 5-ht receptors in the brain. |
2014-09-15 |
2023-08-13 |
mouse |
| Orna Issler, Sharon Haramati, Evan D Paul, Hiroshi Maeno, Inbal Navon, Rayya Zwang, Shosh Gil, Helen S Mayberg, Boadie W Dunlop, Andreas Menke, Rajeshwar Awatramani, Elisabeth B Binder, Evan S Deneris, Christopher A Lowry, Alon Che. MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity. Neuron. vol 83. issue 2. 2014-09-12. PMID:24952960. |
here, we explore the role of micrornas in regulating serotonergic (5ht) neuron activity. |
2014-09-12 |
2023-08-13 |
mouse |
| K E Iceman, M B Harri. A group of non-serotonergic cells is CO2-stimulated in the medullary raphé. Neuroscience. vol 259. 2014-09-11. PMID:24333211. |
subsequent juxtacellular labeling of individually recorded cells, and immunohistochemistry for the serotonin synthesizing enzyme tryptophan hydroxylase and for neurokinin-1 receptor (nk1r; the receptor for substance p) indicated a group of co2-stimulated cells that are not serotonergic, but express nk1r and are closely apposed to surrounding serotonergic cells. |
2014-09-11 |
2023-08-12 |
rat |
| Sanjay Prakash, Pooja Belani, Aditi Trived. Headache as a presenting feature in patients with serotonin syndrome: a case series. Cephalalgia : an international journal of headache. vol 34. issue 2. 2014-09-04. PMID:23827981. |
serotonin syndrome (ss) is a drug-induced constellation of various clinical features that result from excess central serotonergic tone. |
2014-09-04 |
2023-08-12 |
Not clear |
| Meghan R Hennis, Marian A Marvin, Charles M Taylor, Matthew S Goldber. Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinson's disease. Neurobiology of disease. vol 62. 2014-09-03. PMID:24075852. |
stereological analysis indicated that the increased serotonin levels were not due to increased serotonergic projections. |
2014-09-03 |
2023-08-12 |
mouse |
| Nelson D Horseman, Laura L Hernande. New concepts of breast cell communication to bone. Trends in endocrinology and metabolism: TEM. vol 25. issue 1. 2014-09-02. PMID:24055165. |
discovery of serotonergic control of pthrp suggests that it may be possible to manipulate the breast-to-bone axis by targeting serotonin signaling. |
2014-09-02 |
2023-08-12 |
Not clear |
| Joon W Shim, Todd R Dodge, Max A Hammond, Joseph M Wallace, Feng C Zhou, Hiroki Yokot. Physical weight loading induces expression of tryptophan hydroxylase 2 in the brain stem. PloS one. vol 9. issue 1. 2014-09-02. PMID:24416346. |
focusing on serotonergic signaling, we addressed a question: does local mechanical loading to the skeleton elevate expression of tryptophan hydroxylase 2 (tph2) that is a rate-limiting enzyme for brain serotonin? |
2014-09-02 |
2023-08-12 |
mouse |
| Anders Ettrup, Sophie da Cunha-Bang, Brenda McMahon, Szabolcs Lehel, Agnete Dyssegaard, Anine W Skibsted, Louise M Jørgensen, Martin Hansen, Anders O Baandrup, Søren Bache, Claus Svarer, Jesper L Kristensen, Nic Gillings, Jacob Madsen, Gitte M Knudse. Serotonin 2A receptor agonist binding in the human brain with [¹¹C]Cimbi-36. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 7. 2014-09-02. PMID:24780897. |
such an agonist pet radioligand may provide a novel, and more functional, measure of the serotonergic system and agonist binding is more likely than antagonist binding to reflect 5-ht levels in vivo. |
2014-09-02 |
2023-08-13 |
human |
| Naoto Kadoguchi, Shinji Okabe, Yukio Yamamura, Misaki Shono, Tatsuya Fukano, Akie Tanabe, Hironori Yokoyama, Jiro Kasahar. Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson's disease. BMC neuroscience. vol 15. 2014-08-27. PMID:24965042. |
mirtazapine, a noradrenergic and specific serotonergic antidepressant (nassa), shows multiple pharmacological actions such as inhibiting presynaptic α2 noradrenaline receptor (nar) and selectively activating 5-hydroxytriptamine (5-ht) 1a receptor (5-ht1ar). |
2014-08-27 |
2023-08-13 |
mouse |
| Dan A Kim, Willie G McClure, Jordan B Neighoff, Dhananjay Vaidya, Marlene S William. Platelet response to serotonin in patients with stable coronary heart disease. The American journal of cardiology. vol 114. issue 2. 2014-08-26. PMID:24952926. |
given that the pathophysiology of depression is considered to involve disruption in brain serotonergic signaling, we investigated platelet response to serotonin stimulation in patients with stable coronary artery disease (cad). |
2014-08-26 |
2023-08-13 |
Not clear |
| Francisco Espejo-Porras, Javier Fernández-Ruiz, Roger G Pertwee, Raphael Mechoulam, Concepción Garcí. Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors. Neuropharmacology. vol 75. 2014-08-19. PMID:23924692. |
); (vi) the effect of 8-oh-dpat on vertical activity was associated with an increase in serotonin content in the basal ganglia, a neurochemical change not produced by cbd (20 mg/kg); and (vii) cbd at a dose of 20 mg/kg was able to enhance motor effects of a sub-effective dose of 8-oh-dpat (0.1 mg/kg), producing the expected changes in serotonergic transmission in the basal ganglia. |
2014-08-19 |
2023-08-12 |
rat |
| Yan An, Takeshi Inoue, Yuji Kitaichi, Takeshi Izumi, Shin Nakagawa, Ning Song, Chong Chen, XiaoBai Li, Tsukasa Koyama, Ichiro Kusum. Anxiolytic-like effect of mirtazapine mediates its effect in the median raphe nucleus. European journal of pharmacology. vol 720. issue 1-3. 2014-08-15. PMID:24436979. |
mirtazapine, a noradrenergic and specific serotonergic antidepressant (nassa), blocks the α2-adrenergic autoreceptors and heteroreceptors, which are responsible for controlling noradrenaline and 5-hydroxy-tryptamine (5-ht) release. |
2014-08-15 |
2023-08-12 |
rat |