| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Natalie E Scholpa, Sherri B Briggs, John J Wagner, Brian S Cumming. Cyclin-Dependent Kinase Inhibitor 1a (p21) Modulates Response to Cocaine and Motivated Behaviors. The Journal of pharmacology and experimental therapeutics. vol 357. issue 1. 2016-07-19. PMID:26791604. |
pretreatment with a 5-hydroxytryptamine receptor antagonist did not alter the enhancement of cocaine-induced conditioned place preference in p21(-/-) mice, indicating a lack of involvement of serotonergic signaling in this response. |
2016-07-19 |
2023-08-13 |
mouse |
| Claudia Böhm, Maria Pangalos, Dietmar Schmitz, Jochen Wintere. Serotonin Attenuates Feedback Excitation onto O-LM Interneurons. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 11. 2016-07-18. PMID:26021702. |
in the hippocampus, serotonin (5-ht) is released by ascending serotonergic fibers from the midbrain raphe nuclei, thereby mediating numerous modulatory functions on various neuronal subtypes. |
2016-07-18 |
2023-08-13 |
rat |
| S Vanhatalo, S Soinil. Intrahypothalamic Serotonergic Neurons. Nutritional neuroscience. vol 2. issue 6. 2016-07-16. PMID:27416052. |
serotonin's role as a neuronal transmitter was established already forty years ago, and the anatomy and many of the functions of the major serotonergic systems have been carefully mapped. |
2016-07-16 |
2023-08-13 |
Not clear |
| Venlafaxine: more dangerous than most "selective" serotonergic antidepressants. Prescrire international. vol 25. issue 170. 2016-07-15. PMID:27186622. |
it shares the same serotonergic adverse effects as the "selective" serotonin reuptake inhibitor (ssri) antidepressants while in addition provoking noradrenergic adverse effects, in particular cardiovascular disorders, yet offers no demonstrated advantages over ssris in terms of efficacy. |
2016-07-15 |
2023-08-13 |
Not clear |
| Brett Macfarlane, Jenny Bergin, Gregory M Peterso. Assessment and management of serotonin syndrome in a simulated patient study of Australian community pharmacies. Pharmacy practice. vol 14. issue 2. 2016-07-06. PMID:27382424. |
the incidence of serotonin syndrome is increasing due to the widening use of serotonergic drugs. |
2016-07-06 |
2023-08-13 |
Not clear |
| Lars Henning Pederse. Prenatal Antidepressant Exposure and Childhood Autism Spectrum Disorders: Cause for Concern? Paediatric drugs. vol 17. issue 6. 2016-07-01. PMID:26092083. |
in experimental animals, early life exposure to serotonergic antidepressants or maternal stress affects brain development, with subsequent changes in serotonin tone in adult animals. |
2016-07-01 |
2023-08-13 |
Not clear |
| Isabelle E Bauer, David P Graham, Jair C Soares, David A Nielse. Serotonergic gene variation in substance use pharmacotherapy: a systematic review. Pharmacogenomics. vol 16. issue 11. 2016-06-29. PMID:26265436. |
current evidence suggests that genetic variability of the serotonergic biosynthesis enzyme tryptophan hydroxylase 2 (tph2) and the serotonin transporter (slc6a4) genes mediates the efficacy of several addiction treatments, such as ondansetron and disulfiram, and the antidepressants bupropion, nortriptyline and sertraline. |
2016-06-29 |
2023-08-13 |
Not clear |
| Masaki Iwai, Yoshikage Muroi, Ken-ichi Kinoshita, Toshiaki Ishi. Serotonin modulates the dehydration-induced changes in tolerance for bitter water. Physiology & behavior. vol 151. 2016-06-28. PMID:26325013. |
these factors have been suggested to interact with each other via serotonergic (5-ht) signaling to regulate drinking behavior. |
2016-06-28 |
2023-08-13 |
mouse |
| Stephen J Bonasera, A Katrin Schenk, Evan J Luxenberg, Xidao Wang, Allan Basbaum, Laurence H Tecot. Mice Lacking Serotonin 2C Receptors Have increased Affective Responses to Aversive Stimuli. PloS one. vol 10. issue 12. 2016-06-23. PMID:26630489. |
we proposed that serotonin 2c receptors (5-ht2crs), which are expressed within brain regions implicated in sensory and affective responses to pain, contribute to the serotonergic modulation of pain responses. |
2016-06-23 |
2023-08-13 |
mouse |
| Evan M Green, Jonathan A Coleman, Eric Gouau. Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation. PloS one. vol 10. issue 12. 2016-06-23. PMID:26695939. |
modulation of serotonergic signaling occurs, in part, by uptake of the transmitter by the serotonin transporter (sert). |
2016-06-23 |
2023-08-13 |
human |
| L I Khozha. [EXPRESSION OF SEROTONIN TRANSPORTER IN THE DORSAL RAPHE NUCLEUS DURING THE EARLY POSTNATAL PERIOD IN NORMAL STATE AND UNDER PRENATAL DEFICIENCY OF THE SEROTONERGIC SYSTEM IN RATS]. Zhurnal evoliutsionnoi biokhimii i fiziologii. vol 52. issue 1. 2016-06-22. PMID:27220242. |
[expression of serotonin transporter in the dorsal raphe nucleus during the early postnatal period in normal state and under prenatal deficiency of the serotonergic system in rats]. |
2016-06-22 |
2023-08-13 |
rat |
| Galina T Shishkina, Tatyana S Kalinina, Veta V Bulygina, Dmitry A Lanshakov, Ekaterina V Babluk, Nikolay N Dygal. Anti-Apoptotic Protein Bcl-xL Expression in the Midbrain Raphe Region Is Sensitive to Stress and Glucocorticoids. PloS one. vol 10. issue 12. 2016-06-20. PMID:26624017. |
in order to determine whether stressful events may influence the expression of anti-apoptotic protein bcl-xl in the midbrain and specifically in the midbrain serotonergic (5-ht) neurons involved in neurobehavioral responses to adverse stimuli, adult male rats were subjected to short-term or chronic forced swim stress. |
2016-06-20 |
2023-08-13 |
rat |
| Luis A Roble. Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Clinical neuropharmacology. vol 38. issue 5. 2016-06-13. PMID:26366964. |
serotonin syndrome (ss) is a potentially fatal condition associated with increased serotonergic activity in the central nervous system that can be attributed to certain drugs or interactions between drugs. |
2016-06-13 |
2023-08-13 |
Not clear |
| Leonardo Munari, Gustavo Provensi, Maria Beatrice Passani, Nicoletta Galeotti, Tommaso Cassano, Fernando Benetti, Renato Corradetti, Patrizio Blandin. Brain Histamine Is Crucial for Selective Serotonin Reuptake Inhibitors' Behavioral and Neurochemical Effects. The international journal of neuropsychopharmacology. vol 18. issue 10. 2016-06-01. PMID:25899065. |
the neurobiological changes underlying depression resistant to treatments remain poorly understood, and failure to respond to selective serotonin reuptake inhibitors may result from abnormalities of neurotransmitter systems that excite serotonergic neurons, such as histamine. |
2016-06-01 |
2023-08-13 |
Not clear |
| Lu Xu, Sunju Choi, Yusu Xie, Ji Ying Sz. Cell-Autonomous Gβ Signaling Defines Neuron-Specific Steady State Serotonin Synthesis in Caenorhabditis elegans. PLoS genetics. vol 11. issue 9. 2016-05-31. PMID:26402365. |
here, we identified a gβ gpb-1 signaling pathway operating in specific serotonergic neurons to the define steady state serotonin (5-ht) synthesis, through a genetic screen for 5-ht synthesis mutants in caenorhabditis elegans. |
2016-05-31 |
2023-08-13 |
caenorhabditis_elegans |
| Varvara E Dyakonova, Laszlo Hernádi, Etsuro Ito, Taisia L Dyakonova, Ilya A Chistopolsky, Igor S Zakharov, Dmitri A Sakharo. The activity of isolated neurons and the modulatory state of an isolated nervous system represent a recent behavioural state. The Journal of experimental biology. vol 218. issue Pt 8. 2016-05-30. PMID:25714568. |
third, we report that observed hunger-induced effects can be explained by the increased synthesis of serotonin in pedal serotonergic neurons, which has an impact on the electrical activity of isolated serotonergic neurons and the intensity of extrasynaptic serotonin release from the pedal ganglia. |
2016-05-30 |
2023-08-13 |
Not clear |
| Ozgur Yesilyurt, Melik Seyrek, Serdar Tasdemir, Serdar Kahraman, Mehmet Salih Deveci, Emre Karakus, Zekai Halici, Ahmet Dogru. The critical role of spinal 5-HT7 receptors in opioid and non-opioid type stress-induced analgesia. European journal of pharmacology. vol 762. 2016-05-24. PMID:25917322. |
we previously reported that the spinal serotonin 7 receptor (5-ht7) blockers inhibit both morphine and cannabinoid-induced analgesia, thus we hypothesized that descending serotonergic pathways-spinal 5-ht7 receptor loop might contribute to stress-induced analgesia. |
2016-05-24 |
2023-08-13 |
mouse |
| Kannan Baskar, Swastika Sur, Vithyalakshmi Selvaraj, Devendra K Agrawa. Functional constituents of a local serotonergic system, intrinsic to the human coronary artery smooth muscle cells. Molecular biology reports. vol 42. issue 8. 2016-05-23. PMID:25861735. |
we hypothesize that the hcasmc possesses certain functional constituents of the serotonergic system such as: tryptophan hydroxylase and serotonin transporter. |
2016-05-23 |
2023-08-13 |
human |
| Jianfeng Lu, Xuefei Zhong, Huisheng Liu, Ling Hao, Cindy Tzu-Ling Huang, Mohammad Amin Sherafat, Jeffrey Jones, Melvin Ayala, Lingjun Li, Su-Chun Zhan. Generation of serotonin neurons from human pluripotent stem cells. Nature biotechnology. vol 34. issue 1. 2016-05-11. PMID:26655496. |
the serotonin neurons express a series of molecules essential for serotonergic development, including tryptophan hydroxylase 2, exhibit typical electrophysiological properties and release serotonin in an activity-dependent manner. |
2016-05-11 |
2023-08-13 |
human |
| Robin J Tyacke, David J Nut. Optimising PET approaches to measuring 5-HT release in human brain. Synapse (New York, N.Y.). vol 69. issue 10. 2016-05-10. PMID:26089243. |
the serotonergic system (5-ht) is one such system. |
2016-05-10 |
2023-08-13 |
human |