| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David E Nichol. Psychedelics. Pharmacological reviews. vol 68. issue 2. 2016-10-13. PMID:26841800. |
after the virtually contemporaneous discovery of (5r,8r)-(+)-lysergic acid-n,n-diethylamide (lsd)-25 and the identification of serotonin in the brain, early research focused intensively on the possibility that lsd and other psychedelics had a serotonergic basis for their action. |
2016-10-13 |
2023-08-13 |
Not clear |
| Maurizio S Riga, Analia Bortolozzi, Letizia Campa, Francesc Artigas, Pau Celad. The serotonergic hallucinogen 5-methoxy-N,N-dimethyltryptamine disrupts cortical activity in a regionally-selective manner via 5-HT(1A) and 5-HT(2A) receptors. Neuropharmacology. vol 101. 2016-10-05. PMID:26477571. |
the serotonergic hallucinogen 5-methoxy-n,n-dimethyltryptamine disrupts cortical activity in a regionally-selective manner via 5-ht(1a) and 5-ht(2a) receptors. |
2016-10-05 |
2023-08-13 |
mouse |
| Anu Aonurm-Helm, Kaili Anier, Tamara Zharkovsky, Eero Castrén, Tomi Rantamäki, Vladimir Stepanov, Jaak Järv, Alexander Zharkovsk. NCAM-deficient mice show prominent abnormalities in serotonergic and BDNF systems in brain - Restoration by chronic amitriptyline. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26499173. |
serotonergic nerve fiber density and sert (serotonin transporter) protein levels were robustly reduced in the hippocampus, prefrontal cortex and basolateral amygdala of adult ncam(-)(/-) mice. |
2016-10-05 |
2023-08-13 |
mouse |
| Stephan Köhler, Katharina Cierpinsky, Golo Kronenberg, Mazda Adl. The serotonergic system in the neurobiology of depression: Relevance for novel antidepressants. Journal of psychopharmacology (Oxford, England). vol 30. issue 1. 2016-09-26. PMID:26464458. |
antidepressants influencing serotonin mainly aim at raising serotonin concentrations, thereby increasing serotonergic transmission at the level of the synapse, for example by inhibiting the serotonin transporter. |
2016-09-26 |
2023-08-13 |
Not clear |
| Koichi Nisijim. Serotonin syndrome overlapping with neuroleptic malignant syndrome: A case report and approaches for differentially diagnosing the two syndromes. Asian journal of psychiatry. vol 18. 2016-09-26. PMID:26506919. |
serotonin syndrome (ss) and neuroleptic malignant syndrome (nms) are life-threatening adverse reactions caused by serotonergic antidepressants and neuroleptics, respectively. |
2016-09-26 |
2023-08-13 |
Not clear |
| Diana M Gerardi, Tanya K Murphy, Megan Toufexis, Camille Hank. Serotonergic or Anticholinergic Toxidrome: Case Report of a 9-Year-Old Girl. Pediatric emergency care. vol 31. issue 12. 2016-09-22. PMID:26425930. |
the aim of this study was to report an acute onset of symptoms erroneously attributed to serotonin syndrome in a child who had been given both anticholinergic and serotonergic agents. |
2016-09-22 |
2023-08-13 |
Not clear |
| Jong-Hoon Kim, Young-Don Son, Jeong-Hee Kim, Eun-Jung Choi, Sang-Yoon Lee, Yo-Han Joo, Young-Bo Kim, Zang-Hee Ch. Self-transcendence trait and its relationship with in vivo serotonin transporter availability in brainstem raphe nuclei: An ultra-high resolution PET-MRI study. Brain research. vol 1629. 2016-09-22. PMID:26459992. |
we examined the relationship between self-transcendence and serotonin transporter (sert) availability in brainstem raphe nuclei, which are collections of five different serotonergic nuclei with rostro-caudal extension, using ultra-high resolution magnetic resonance imaging (mri) and positron emission tomography (pet) with (11)c-3-amino-4-(2-dimethylaminomethylphenylthio)benzonitrile ([(11)c]dasb) to elucidate potential roles of serotonergic neuronal activities in this personality trait. |
2016-09-22 |
2023-08-13 |
human |
| Fredrik Åhs, Andreas Frick, Tomas Furmark, Mats Fredrikso. Human serotonin transporter availability predicts fear conditioning. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 98. issue 3 Pt 2. 2016-09-21. PMID:25498766. |
the capacity to regulate serotonergic transmission was indexed by serotonin transporter availability measured with [(11)c]-dasb positron emission tomography. |
2016-09-21 |
2023-08-13 |
human |
| Friederike Matthaeus, Patrick Schloss, Thorsten La. Differential Uptake Mechanisms of Fluorescent Substrates into Stem-Cell-Derived Serotonergic Neurons. ACS chemical neuroscience. vol 6. issue 12. 2016-09-21. PMID:26503837. |
using selective antagonists, we provide evidence that uptake of the fluorescent substrates ffn511, asp+, and 5-ht into stem cell-derived serotonergic neurons is mediated differentially by these transporters and also involves an as yet unknown transport mechanism. |
2016-09-21 |
2023-08-13 |
Not clear |
| Zacharias Kohl, Nada Ben Abdallah, Jonathan Vogelgsang, Lucas Tischer, Janina Deusser, Davide Amato, Scott Anderson, Christian P Müller, Olaf Riess, Eliezer Masliah, Silke Nuber, Jürgen Winkle. Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease. Neurobiology of disease. vol 85. 2016-09-21. PMID:26523794. |
diminished neurogenesis concurred with a serotonergic deficit in the hippocampus as defined by reduced levels of serotonin (5-ht) 1b receptor, decreased 5-ht neurotransmitter levels, and a loss of serotonergic nerve terminals innervating the dg/ca3 subfield, while the number of serotonergic neurons in the raphe nuclei remained unchanged. |
2016-09-21 |
2023-08-13 |
human |
| Melissa J Maguire, Cerian F Jackson, Anthony G Marson, Sarah J Nola. Treatments for the prevention of Sudden Unexpected Death in Epilepsy (SUDEP). The Cochrane database of systematic reviews. vol 7. 2016-09-21. PMID:27434597. |
preventative strategies for sudep include reducing the occurrence of gtcs by timely referral for presurgical evaluation in people with lesional epilepsy and advice on lifestyle measures; detecting cardiorespiratory distress through clinical observation and seizure, respiratory, and heart rate monitoring devices; preventing airway obstruction through nocturnal supervision and safety pillows; reducing central hypoventilation through physical stimulation and enhancing serotonergic mechanisms of respiratory regulation using selective serotonin reuptake inhibitors (ssris); reducing adenosine and endogenous opioid-induced brain and brainstem depression. |
2016-09-21 |
2023-08-13 |
Not clear |
| Z Xu, H Jiang, P Zhong, Z Yan, S Chen, J Fen. Direct conversion of human fibroblasts to induced serotonergic neurons. Molecular psychiatry. vol 21. issue 1. 2016-09-16. PMID:26216300. |
serotonergic (5ht) neurons exert diverse and widespread functions in the brain. |
2016-09-16 |
2023-08-13 |
human |
| Z Xu, H Jiang, P Zhong, Z Yan, S Chen, J Fen. Direct conversion of human fibroblasts to induced serotonergic neurons. Molecular psychiatry. vol 21. issue 1. 2016-09-16. PMID:26216300. |
the i5ht neurons expressed markers for mature serotonergic neurons, had ca(2+)-dependent 5ht release and selective 5ht uptake, exhibited spontaneous action potentials and spontaneous excitatory postsynaptic currents. |
2016-09-16 |
2023-08-13 |
human |
| Z Xu, H Jiang, P Zhong, Z Yan, S Chen, J Fen. Direct conversion of human fibroblasts to induced serotonergic neurons. Molecular psychiatry. vol 21. issue 1. 2016-09-16. PMID:26216300. |
application of serotonin significantly increased the firing rate of spontaneous action potentials, demonstrating the functional utility of i5ht neurons for studying serotonergic neurotransmission. |
2016-09-16 |
2023-08-13 |
human |
| Ibrahim M Shokry, John J Callanan, John Sousa, Rui Ta. Rapid In Situ Hybridization using Oligonucleotide Probes on Paraformaldehyde-prefixed Brain of Rats with Serotonin Syndrome. Journal of visualized experiments : JoVE. issue 103. 2016-09-16. PMID:26437182. |
3,4-methylenedioxymethamphetamine (mdma; ecstasy) toxicity may cause region-specific changes in serotonergic mrna expression due to acute serotonin (5-hydroxytryptamine; 5-ht) syndrome. |
2016-09-16 |
2023-08-13 |
rat |
| Sigal Rozenblit-Susan, Nava Chapnik, Yoni Genzer, Oren Fro. Serotonin suppresses food anticipatory activity and synchronizes the food-entrainable oscillator during time-restricted feeding. Behavioural brain research. vol 297. 2016-09-15. PMID:26467604. |
the serotonergic and circadian systems are intertwined as serotonin modulates the response of the central brain suprachiasmatic nuclei (scn) clock to light. |
2016-09-15 |
2023-08-13 |
mouse |
| Sonoe Kitamura, Takashi Kawano, Satomi Kaminaga, Daiki Yamanaka, Hiroki Tateiwa, Fabricio M Locatelli, Masataka Yokoyam. Effects of fentanyl on serotonin syndrome-like behaviors in rats. Journal of anesthesia. vol 30. issue 1. 2016-09-15. PMID:26499475. |
emerging evidence from case reports suggests that fentanyl may precipitate potentially life-threatening serotonin syndrome in patients taking serotonergic drugs. |
2016-09-15 |
2023-08-13 |
rat |
| Shih-Hui Hsu, Kun-Ze Le. Effects of serotonergic agents on respiratory recovery after cervical spinal injury. Journal of applied physiology (Bethesda, Md. : 1985). vol 119. issue 10. 2016-09-12. PMID:26359482. |
a bolus intravenous injection of a serotonin precursor [5-hydroxytryptophan (5-htp), 10 mg/kg], a serotonin reuptake inhibitor (fluoxetine, 10 mg/kg), or a potent agonist for serotonin 2a receptors (tcb-2, 0.05 mg/kg) was used to activate the serotonergic system. |
2016-09-12 |
2023-08-13 |
rat |
| Gitte M Knudsen, Peter S Jensen, David Erritzoe, William F C Baaré, Anders Ettrup, Patrick M Fisher, Nic Gillings, Hanne D Hansen, Lars Kai Hansen, Steen G Hasselbalch, Susanne Henningsson, Matthias M Herth, Klaus K Holst, Pernille Iversen, Lars V Kessing, Julian Macoveanu, Kathrine Skak Madsen, Erik L Mortensen, Finn Årup Nielsen, Olaf B Paulson, Hartwig R Siebner, Dea S Stenbæk, Claus Svarer, Terry L Jernigan, Stephen C Strother, Vibe G Frokjae. The Center for Integrated Molecular Brain Imaging (Cimbi) database. NeuroImage. vol 124. issue Pt B. 2016-09-06. PMID:25891375. |
the data is of particular relevance for neurobiological research questions related to the serotonergic transmitter system with its normative data on the serotonergic subtype receptors 5-ht1a, 5-ht1b, 5-ht2a, and 5-ht4 and the 5-ht transporter (5-htt), but can easily serve other purposes. |
2016-09-06 |
2023-08-13 |
human |
| Patrick D Ganzer, Anitha Manohar, Jed S Shumsky, Karen A Moxo. Therapy induces widespread reorganization of motor cortex after complete spinal transection that supports motor recovery. Experimental neurology. vol 279. 2016-09-06. PMID:26826448. |
in this study we assessed the effect of passive exercise and serotonergic (5-ht) pharmacological therapies on behavioral recovery and organization of the motor cortex. |
2016-09-06 |
2023-08-13 |
rat |