| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Inaba, Y Komori, Y Muroi, K Kinoshita, T Ishi. Neuropeptide Y signaling in the dorsal raphe nucleus inhibits male sexual behavior in mice. Neuroscience. vol 320. 2016-12-13. PMID:26868970. |
we next examined whether the dorsal raphe nucleus (drn), in which serotonergic (5-ht) neurons are distributed, is involved in npy-mediated inhibition of male sexual behavior. |
2016-12-13 |
2023-08-13 |
mouse |
| Aileen Echiverri-Cohen, Lori A Zoellner, Robert Gallop, Norah Feeny, Jeffrey Jaeger, Michele Bedard-Gilliga. Changes in temporal attention inhibition following prolonged exposure and sertraline in the treatment of PTSD. Journal of consulting and clinical psychology. vol 84. issue 5. 2016-12-13. PMID:26900894. |
evidence of inhibitory processes as central to extinction suggests that exposure-based treatments may act more directly on the inhibitory deficits implicated in ptsd, whereas, in facilitating serotonergic neurotransmission, selective serotonin reuptake inhibitors (ssris) may be less direct and bring about general neurochemical changes in the fear circuitry. |
2016-12-13 |
2023-08-13 |
Not clear |
| Laura Hencken, Long To, Nancy Ly, Jeffrey A Morga. Serotonin Syndrome Following Methylene Blue Administration for Vasoplegic Syndrome. Journal of cardiac surgery. vol 31. issue 4. 2016-12-13. PMID:26934199. |
methylene blue (mb) has been used for additional blood pressure support in patients who develop severe, refractory vasoplegia; however, mb can induce serotonin syndrome, especially when used in conjunction with other serotonergic agents. |
2016-12-13 |
2023-08-13 |
Not clear |
| Mathieu Verdurand, Fabien Chauveau, Alexia Daoust, Anne-Laure Morel, Frédéric Bonnefoi, François Liger, Anne Bérod, Luc Zimme. Differential effects of amyloid-beta 1-40 and 1-42 fibrils on 5-HT1A serotonin receptors in rat brain. Neurobiology of aging. vol 40. 2016-12-13. PMID:26973100. |
this serotonergic reactivity paralleled results from clinical positron emission tomography studies with [(18)f]mppf revealing an overexpression of 5-ht(1a)r in the hippocampus of patients with mild cognitive impairment. |
2016-12-13 |
2023-08-13 |
rat |
| Yi-Xiang Qi, Jia Huang, Meng-Qi Li, Ya-Su Wu, Ren-Ying Xia, Gong-Yin Y. Serotonin modulates insect hemocyte phagocytosis via two different serotonin receptors. eLife. vol 5. 2016-12-13. PMID:26974346. |
combined, these data demonstrate that 5-ht mediates hemocyte phagocytosis through 5-ht1b and 5-ht2b receptors and serotonergic signaling performs critical modulatory functions in immune systems of animals separated by 500 million years of evolution. |
2016-12-13 |
2023-08-13 |
drosophila_melanogaster |
| James Francescangeli, Sonia Vaida, Anthony S Bonavi. Perioperative Diagnosis and Treatment of Serotonin Syndrome Following Administration of Methylene Blue. The American journal of case reports. vol 17. 2016-12-13. PMID:27210537. |
serotonin syndrome (ss) involves serotonergic hyperactivity caused by excessive activation of 5-ht2a receptors. |
2016-12-13 |
2023-08-13 |
Not clear |
| N N Pettit, V Alonso, E Wojcik, E C Anyanwu, L Ebara, J-L Benoi. Possible serotonin syndrome with carbidopa-levodopa and linezolid. Journal of clinical pharmacy and therapeutics. vol 41. issue 1. 2016-10-31. PMID:26813986. |
serotonin syndrome (ss) can occur when linezolid is combined with other serotonergic agents. |
2016-10-31 |
2023-08-13 |
Not clear |
| Jui-Hu Shih, Kuo-Hsing Ma, Chien-Fu F Chen, Cheng-Yi Cheng, Li-Heng Pao, Shao-Ju Weng, Yuahn-Sieh Huang, Chyng-Yann Shiue, Ming-Kung Yeh, I-Hsun L. Evaluation of brain SERT occupancy by resveratrol against MDMA-induced neurobiological and behavioral changes in rats: A 4-[¹⁸F]-ADAM/small-animal PET study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 1. 2016-10-27. PMID:26612383. |
mdma abusers are often accompanied by long-term serotonergic neurotoxicity, which is associated with reduced density of cerebral serotonin transporters (sert) and depressive disorders. |
2016-10-27 |
2023-08-13 |
rat |
| N Ahmadi-Mahmoodabadi, M Nasehi, M Emam Ghoreishi, M-R Zarrindas. Synergistic effect between prelimbic 5-HT3 and CB1 receptors on memory consolidation deficit in adult male Sprague-Dawley rats: An isobologram analysis. Neuroscience. vol 317. 2016-10-24. PMID:26701293. |
the present study investigated the influence of bilateral post-training intra-prelimbic (pl) administrations of serotonergic 5-hydroxytryptamine type-3 (5-ht3) receptor agents on arachidonylcyclopropylamide (acpa) (cannabinoid cb1 receptor agonist)-induced amnesia, using the step-through inhibitory avoidance (ia) task to assess memory in adult male sprague-dawley rats. |
2016-10-24 |
2023-08-13 |
rat |
| Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska, Władysława A Danie. Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain. Drug metabolism and disposition: the biological fate of chemicals. vol 44. issue 3. 2016-10-24. PMID:26884482. |
melatonin increased the tissue concentration of serotonin in the brain structures studied of naïve, sham-operated, or serotonergic neurotoxin (5,7-dihydroxytryptamine)-lesioned rats (model a). |
2016-10-24 |
2023-08-13 |
rat |
| Nina C Donner, Philip H Siebler, Danté T Johnson, Marcos D Villarreal, Sofia Mani, Allison J Matti, Christopher A Lowr. Serotonergic systems in the balance: CRHR1 and CRHR2 differentially control stress-induced serotonin synthesis. Psychoneuroendocrinology. vol 63. 2016-10-19. PMID:26454419. |
serotonergic systems in the balance: crhr1 and crhr2 differentially control stress-induced serotonin synthesis. |
2016-10-19 |
2023-08-13 |
rat |
| Nina C Donner, Philip H Siebler, Danté T Johnson, Marcos D Villarreal, Sofia Mani, Allison J Matti, Christopher A Lowr. Serotonergic systems in the balance: CRHR1 and CRHR2 differentially control stress-induced serotonin synthesis. Psychoneuroendocrinology. vol 63. 2016-10-19. PMID:26454419. |
anxiety and affective disorders are often associated with hypercortisolism and dysfunctional serotonergic systems, including increased expression of tph2, the gene encoding the rate-limiting enzyme of neuronal serotonin synthesis. |
2016-10-19 |
2023-08-13 |
rat |
| Nina C Donner, Philip H Siebler, Danté T Johnson, Marcos D Villarreal, Sofia Mani, Allison J Matti, Christopher A Lowr. Serotonergic systems in the balance: CRHR1 and CRHR2 differentially control stress-induced serotonin synthesis. Psychoneuroendocrinology. vol 63. 2016-10-19. PMID:26454419. |
our data demonstrate that chronically elevated glucocorticoids sensitize stress- and anxiety-related serotonergic systems, and for the first time reveal competing roles of crhr1 and crhr2 on stress-induced in vivo serotonin synthesis. |
2016-10-19 |
2023-08-13 |
rat |
| Monika Kubacka, Szczepan Mogilski, Marek Bednarski, Leszek Nowiński, Magdalena Dudek, Elżbieta Żmudzka, Agata Siwek, Anna M Waszkielewicz, Henryk Marona, Grzegorz Satała, Andrzej Bojarski, Barbara Filipek, Karolina Pytk. Antidepressant-like activity of aroxyalkyl derivatives of 2-methoxyphenylpiperazine and evidence for the involvement of serotonin receptor subtypes in their mechanism of action. Pharmacology, biochemistry, and behavior. vol 141. 2016-10-19. PMID:26647362. |
since serotonin (5-ht) is strongly involved in the etiology and pathophysiology of depression, the development of new antidepressants is still based on the serotonergic system. |
2016-10-19 |
2023-08-13 |
Not clear |
| Laura Guerra, John G Stoffolano, Maria Cristina Belardinelli, Anna Maria Faust. Serotonergic Innervation of the Salivary Glands and Central Nervous System of Adult Glossina pallidipes Austen (Diptera: Glossinidae), and the Impact of the Salivary Gland Hypertrophy Virus (GpSGHV) on the Host. Journal of insect science (Online). vol 16. 2016-10-19. PMID:26798144. |
using a serotonin antibody and confocal microscopy, this study reports for the first time direct serotonergic innervation of the muscle sheath covering the secretory region of the salivary glands of adult tsetse fly, glossina pallidipes austen. |
2016-10-19 |
2023-08-13 |
Not clear |
| Hamid Moha ou Maati, Céline Bourcier-Lucas, Julie Veyssiere, Ameni Kanzari, Catherine Heurteaux, Marc Borsotto, Nasser Haddjeri, Guillaume Luca. The peptidic antidepressant spadin interacts with prefrontal 5-HT(4) and mGluR(2) receptors in the control of serotonergic function. Brain structure & function. vol 221. issue 1. 2016-10-14. PMID:25233810. |
the peptidic antidepressant spadin interacts with prefrontal 5-ht(4) and mglur(2) receptors in the control of serotonergic function. |
2016-10-14 |
2023-08-13 |
Not clear |
| Hamid Moha ou Maati, Céline Bourcier-Lucas, Julie Veyssiere, Ameni Kanzari, Catherine Heurteaux, Marc Borsotto, Nasser Haddjeri, Guillaume Luca. The peptidic antidepressant spadin interacts with prefrontal 5-HT(4) and mGluR(2) receptors in the control of serotonergic function. Brain structure & function. vol 221. issue 1. 2016-10-14. PMID:25233810. |
this study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (ad) and a functional blocker of the k(+) trek-1 channel, in relation with the medial prefrontal cortex (mpfc)-dorsal raphé (drn) serotonergic (5-ht) neurons connectivity. |
2016-10-14 |
2023-08-13 |
Not clear |
| Veronica Ghiglieri, Desiree Mineo, Anna Vannelli, Fabrizio Cacace, Maria Mancini, Valentina Pendolino, Francesco Napolitano, Anna di Maio, Manuela Mellone, Jennifer Stanic, Elisabetta Tronci, Camino Fidalgo, Roberto Stancampiano, Manolo Carta, Paolo Calabresi, Fabrizio Gardoni, Alessandro Usiello, Barbara Piccon. Modulation of serotonergic transmission by eltoprazine in L-DOPA-induced dyskinesia: Behavioral, molecular, and synaptic mechanisms. Neurobiology of disease. vol 86. 2016-10-14. PMID:26639853. |
despite the fact that several papers have tested this and other serotonergic drugs, nothing is known about the electrophysiological consequences on this combined serotonin receptors modulation at striatal neurons. |
2016-10-14 |
2023-08-13 |
human |
| Victoria M Smith, Ryan T Jeffers, Michael C Antl. Serotonergic enhancement of circadian responses to light: role of the raphe and intergeniculate leaflet. The European journal of neuroscience. vol 42. issue 10. 2016-10-13. PMID:26457682. |
some serotonergic drugs that bind to the serotonin 1a receptor can enhance phase shifts to light. |
2016-10-13 |
2023-08-13 |
Not clear |
| Victoria M Smith, Ryan T Jeffers, Michael C Antl. Serotonergic enhancement of circadian responses to light: role of the raphe and intergeniculate leaflet. The European journal of neuroscience. vol 42. issue 10. 2016-10-13. PMID:26457682. |
potentiation of photic shifts persisted when serotonergic innervation of the scn was lesioned with infusions of the serotonin neurotoxin 5,7-dihydroxytryptamine into the scn. |
2016-10-13 |
2023-08-13 |
Not clear |