| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephanie W Watt. Oh, the places you'll go! My many colored serotonin (apologies to Dr. Seuss). American journal of physiology. Heart and circulatory physiology. vol 311. issue 5. 2017-06-30. PMID:27663771. |
this manuscript takes you through a brief history of the discovery of 5-ht, in vitro serotonergic pharmacology of blood vessels, in vivo work with 5-ht and our studies that suggests the venous vasculature, potentially in combination with small arterioles, may be important to the actions of 5-ht in reducing blood pressure. |
2017-06-30 |
2023-08-13 |
human |
| Gennaro Pagano, Flavia Niccolini, Paolo Fusar-Poli, Marios Politi. Serotonin transporter in Parkinson's disease: A meta-analysis of positron emission tomography studies. Annals of neurology. vol 81. issue 2. 2017-06-30. PMID:28019672. |
over the past years, a number of pet studies imaging the serotonin transporter (sert) have been used and provided evidence for the key role of serotonergic pathology in patients with parkinson's disease (pd). |
2017-06-30 |
2023-08-13 |
human |
| Laura Arroyo, Ricard Carreras, Daniel Valent, Raquel Peña, Eva Mainau, Antonio Velarde, Josefa Sabrià, Anna Bassol. Effect of handling on neurotransmitter profile in pig brain according to fear related behaviour. Physiology & behavior. vol 167. 2017-06-27. PMID:27737780. |
the most crucial pathway involved in the reaction of pigs to a stressful handling was the serotonergic system, and changes were observed in the amygdala with a decrease in serotonin (5-ht) and total indoleamines, and in the hippocampus, where this pathway was activated. |
2017-06-27 |
2023-08-13 |
Not clear |
| Andrew C McCreary, Mark A Varney, Adrian Newman-Tancred. The novel 5-HT1A receptor agonist, NLX-112 reduces l-DOPA-induced abnormal involuntary movements in rat: A chronic administration study with microdialysis measurements. Neuropharmacology. vol 105. 2017-06-21. PMID:26777281. |
administration over 14 days and was accompanied by pronounced decrease of striatal 5-ht extracellular levels, as measured by in vivo microdialysis, indicative of the inhibition of serotonergic activity. |
2017-06-21 |
2023-08-13 |
rat |
| Bruna Balbino de Paula, Christie Ramos Andrade Leite-Paniss. Distinct effect of 5-HT1A and 5-HT2A receptors in the medial nucleus of the amygdala on tonic immobility behavior. Brain research. vol 1643. 2017-06-21. PMID:27150816. |
considering that a major drug class used for the treatment of psychopathology is based on serotonin (5-ht) neurotransmission, we investigated the effects of serotonergic receptor activation in the mea on the duration of ti. |
2017-06-21 |
2023-08-13 |
Not clear |
| Adam L Halberstadt, Ivan S Sindhunata, Kees Scheffers, Aaron D Flynn, Richard F Sharp, Mark A Geyer, Jared W Youn. Effect of 5-HT2A and 5-HT2C receptors on temporal discrimination by mice. Neuropharmacology. vol 107. 2017-06-19. PMID:27020041. |
characterizing the mechanism through which the serotonergic system regulates timing will increase our understanding of the linkage between serotonin (5-ht) and schizophrenia, and will provide insight into the mechanism of action of hallucinogens. |
2017-06-19 |
2023-08-13 |
mouse |
| Adam L Halberstadt, Ivan S Sindhunata, Kees Scheffers, Aaron D Flynn, Richard F Sharp, Mark A Geyer, Jared W Youn. Effect of 5-HT2A and 5-HT2C receptors on temporal discrimination by mice. Neuropharmacology. vol 107. 2017-06-19. PMID:27020041. |
it appears that 5-ht regulates temporal perception, suggesting that altered serotonergic signaling may contribute to the timing deficits observed in schizophrenia and other psychiatric disorders. |
2017-06-19 |
2023-08-13 |
mouse |
| Makoto Takahashi, Junichi Tanak. Serotonin release in the subfornical organ area induced by sodium and water intake in the rat. Physiology & behavior. vol 164. issue Pt A. 2017-06-19. PMID:27117815. |
to clarify whether serotonergic mechanisms in the sfo participate in the modulatory system, the present study was carried out to examine the effects of sodium and water intake on serotonin (5-hydroxytryptamine, 5-ht) release in the subfornical organ (sfo) in freely moving rats. |
2017-06-19 |
2023-08-13 |
rat |
| Anzelle Delport, Brian H Harvey, Anél Petzer, Jacobus P Petze. The monoamine oxidase inhibition properties of selected structural analogues of methylene blue. Toxicology and applied pharmacology. vol 325. 2017-05-30. PMID:28377303. |
the central inhibition of mao-a by mb has also been linked to serotonin toxicity (st) which may arise when mb is used in combination with serotonergic drugs. |
2017-05-30 |
2023-08-13 |
human |
| Marta Rysz, Ewa Bromek, Anna Haduch, Barbora Liskova, Jacek Wójcikowski, Władysława A Danie. The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11. Biochemical pharmacology. vol 112. 2017-05-23. PMID:27137992. |
lesion of the serotonergic innervation of the pvn decreased serotonin level in the hypothalamic area containing the pvn, causing an increase in growth hormone and testosterone concentrations in the blood and, subsequently, an increase in the expression (mrna and protein level) and activity of isoform cyp2c11 in the liver. |
2017-05-23 |
2023-08-13 |
rat |
| Marta Rysz, Ewa Bromek, Anna Haduch, Barbora Liskova, Jacek Wójcikowski, Władysława A Danie. The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11. Biochemical pharmacology. vol 112. 2017-05-23. PMID:27137992. |
in contrast, damage to the serotonergic innervation of the arc, which caused a decrease in serotonin level in the hypothalamic area containing the arc, reduced the concentration of growth hormone and the expression and activity of cyp2c11. |
2017-05-23 |
2023-08-13 |
rat |
| Pascal Seyer, Franck Vandermoere, Elisabeth Cassier, Joël Bockaert, Philippe Mari. Physical and functional interactions between the serotonin transporter and the neutral amino acid transporter ASCT2. The Biochemical journal. vol 473. issue 13. 2017-05-15. PMID:27143784. |
the activity of serotonergic systems depends on the reuptake of extracellular serotonin via its plasma membrane serotonin [5-ht (5-hydroxytryptamine)] transporter (sert), a member of the na(+)/cl(-)-dependent solute carrier 6 family. |
2017-05-15 |
2023-08-13 |
human |
| Anne Gautier, Hanady El Ouaraki, Natacha Bazin, Soha Salam, Guilan Vodjdani, Sylvie Bourgoin, Sophie Pezet, Jean-François Bernard, Michel Hamo. Lentiviral vector-driven inhibition of 5-HT synthesis in B3 bulbo-spinal serotonergic projections - Consequences on nociception, inflammatory and neuropathic pain in rats. Experimental neurology. vol 288. 2017-05-12. PMID:27983993. |
lentiviral vector-driven inhibition of 5-ht synthesis in b3 bulbo-spinal serotonergic projections - consequences on nociception, inflammatory and neuropathic pain in rats. |
2017-05-12 |
2023-08-13 |
rat |
| Anne Gautier, Hanady El Ouaraki, Natacha Bazin, Soha Salam, Guilan Vodjdani, Sylvie Bourgoin, Sophie Pezet, Jean-François Bernard, Michel Hamo. Lentiviral vector-driven inhibition of 5-HT synthesis in B3 bulbo-spinal serotonergic projections - Consequences on nociception, inflammatory and neuropathic pain in rats. Experimental neurology. vol 288. 2017-05-12. PMID:27983993. |
in contrast, immunolabeling of the 5-ht transporter was unaffected by lv-shtph2 injection, indicating the preservation of serotonergic fibers integrity. |
2017-05-12 |
2023-08-13 |
rat |
| Taku Harada, Takanobu Hirosawa, Kouhei Morinaga, Taro Shimiz. Metoclopramide-induced Serotonin Syndrome. Internal medicine (Tokyo, Japan). vol 56. issue 6. 2017-05-09. PMID:28321081. |
her medical history, which included the use of serotonergic agents, and the presence of symptoms including myoclonus and muscle rigidity were consistent with a diagnosis of serotonin syndrome (ss) according to the hunter criteria. |
2017-05-09 |
2023-08-13 |
Not clear |
| Luciana S Dorelle, Rodrigo H Da Cuña, Graciela Rey Vázquez, Christian Höcht, Akio Shimizu, Griselda Genovese, Fabiana L Lo Nostr. The SSRI fluoxetine exhibits mild effects on the reproductive axis in the cichlid fish Cichlasoma dimerus (Teleostei, Cichliformes). Chemosphere. vol 171. 2017-05-01. PMID:28030789. |
it inhibits serotonin (5-ht) reuptake at the presinaptic membrane, increasing serotonergic activity. |
2017-05-01 |
2023-08-13 |
Not clear |
| Karolina Pytka, Grzegorz Kazek, Agata Siwek, Barbara Mordyl, Monika Głuch-Lutwin, Anna Rapacz, Adrian Olczyk, Adam Gałuszka, Anna Waszkielewicz, Henryk Marona, Jacek Sapa, Barbara Filipek, Małgorzata Zygmun. HBK-7 - A new xanthone derivative and a 5-HT1A receptor antagonist with antidepressant-like properties. Pharmacology, biochemistry, and behavior. vol 146-147. 2017-04-25. PMID:27132236. |
hbk-7 showed moderate affinity for dopaminergic d2 receptor and very low for serotonergic 5-ht2a, adrenergic α2 receptors, as well as serotonin transporter. |
2017-04-25 |
2023-08-13 |
mouse |
| Marta Pratelli, Sara Migliarini, Barbara Pelosi, Francesco Napolitano, Alessandro Usiello, Massimo Pasqualett. Perturbation of Serotonin Homeostasis during Adulthood Affects Serotonergic Neuronal Circuitry. eNeuro. vol 4. issue 2. 2017-04-24. PMID:28413824. |
perturbation of serotonin homeostasis during adulthood affects serotonergic neuronal circuitry. |
2017-04-24 |
2023-08-13 |
Not clear |
| Marie Deen, Casper Emil Christensen, Anders Hougaard, Hanne Demant Hansen, Gitte Moos Knudsen, Messoud Ashin. Serotonergic mechanisms in the migraine brain - a systematic review. Cephalalgia : an international journal of headache. vol 37. issue 3. 2017-04-20. PMID:27013238. |
serotonin is a key molecule in the neurobiology of migraine, but the exact role of brain serotonergic mechanisms remains a matter of controversy. |
2017-04-20 |
2023-08-13 |
Not clear |
| Claudia Francesca Gasparini, Robert Anthony Smith, Lyn Robyn Griffith. Genetic and biochemical changes of the serotonergic system in migraine pathobiology. The journal of headache and pain. vol 18. issue 1. 2017-04-13. PMID:28194570. |
genetic and biochemical studies have primarily focused on the neurotransmitter serotonin, considering receptor binding, transport and synthesis of serotonin and have investigated serotonergic mediators including enzymes, receptors as well as intermediary metabolites. |
2017-04-13 |
2023-08-13 |
Not clear |