| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Awanish Mishra, Rajesh Kumar Goe. Chronic 5-HT Neuroscience. vol 339. 2017-11-06. PMID:27746348. |
chronic 5-ht our previous studies have suggested a strong involvement of serotonergic innervations in epileptogenesis and associated memory impairment. |
2017-11-06 |
2023-08-13 |
Not clear |
| Shun Wang, Zhe Dong, Shen Li, Haotian Yin, Zhifu Zhao, Dongmei Gao, Guimin Ren, Xuexiang Ba. Identification and Expression Analysis of Tryptophan Hydroxylase in the Brain and Ventral Nerve Cord of Ragworm Neanthes japonica (Polychaeta, Annelida). Anatomical record (Hoboken, N.J. : 2007). vol 300. issue 2. 2017-11-03. PMID:27775878. |
the co-localization of tph and 5-ht indicated that the specific tph was responsible for the central serotonin synthesis in the central nervous system of annelida, tph and 5-ht not only could be as the novel mutual corroboration marker to detect serotonergic neurons, but also provides the evidences for the evolution of aromatic amino acid hydroxylase genes. |
2017-11-03 |
2023-08-13 |
Not clear |
| Michael K Tian, Eric F Schmidt, Evelyn K Lamb. Serotonergic Suppression of Mouse Prefrontal Circuits Implicated in Task Attention. eNeuro. vol 3. issue 5. 2017-10-26. PMID:27844060. |
layer 6 (l6) pyramidal neurons of prefrontal cortex play an important role in attention and express 5-ht receptors, but the serotonergic modulation of this layer and its excitatory output is not known. |
2017-10-26 |
2023-08-13 |
mouse |
| Michael K Tian, Eric F Schmidt, Evelyn K Lamb. Serotonergic Suppression of Mouse Prefrontal Circuits Implicated in Task Attention. eNeuro. vol 3. issue 5. 2017-10-26. PMID:27844060. |
this work helps to build a neurobiological framework to appreciate serotonergic disruption of task attention and yields insight into the disruptions of attention observed in psychiatric disorders with altered 5-ht receptors and signaling. |
2017-10-26 |
2023-08-13 |
mouse |
| M Smit, A L Bartels, M van Faassen, A Kuiper, K E Niezen-Koning, I P Kema, R A Dierckx, T J de Koning, M A Tijsse. Serotonergic perturbations in dystonia disorders-a systematic review. Neuroscience and biobehavioral reviews. vol 65. 2017-10-19. PMID:27073048. |
an association between dystonia and the serotonergic system was reported with decreased levels of 5-hydroxyindolacetic acid, the main metabolite of serotonin. |
2017-10-19 |
2023-08-13 |
human |
| John D Chan, Sreemoyee Acharya, Timothy A Day, Jonathan S Marchan. Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist. International journal for parasitology. Drugs and drug resistance. vol 6. issue 3. 2017-10-16. PMID:27397763. |
in schistosoma mansoni, the myoexcitatory action of 5-ht is effected through activation of a serotonergic gpcr (sm.5htr |
2017-10-16 |
2023-08-13 |
Not clear |
| Dea Siggaard Stenbæk, Vibeke Høyrup Dam, Patrick MacDonald Fisher, Nanna Hansen, Liv Vadskjær Hjordt, Vibe Gedsoe Frokjae. No evidence for a role of the serotonin 4 receptor in five-factor personality traits: A positron emission tomography brain study. PloS one. vol 12. issue 9. 2017-10-16. PMID:28880910. |
this is particularly relevant since availability of 5-ht4r has been shown to adapt to synaptic levels of 5-ht and thus offers information about serotonergic tone in the healthy brain. |
2017-10-16 |
2023-08-13 |
human |
| Ephraim F Trakhtenberg, Wolfgang Pita-Thomas, Stephanie G Fernandez, Karan H Patel, Praseeda Venugopalan, Jesse M Shechter, Melina I Morkin, Joana Galvao, Xiongfei Liu, Susan M Dombrowski, Jeffrey L Goldber. Serotonin receptor 2C regulates neurite growth and is necessary for normal retinal processing of visual information. Developmental neurobiology. vol 77. issue 4. 2017-10-13. PMID:26999672. |
serotonin (5ht) is present in a subpopulation of amacrine cells, which form synapses with retinal ganglion cells (rgcs), but little is known about the physiological role of retinal serotonergic circuitry. |
2017-10-13 |
2023-08-13 |
mouse |
| Vincent van de Ven, Marleen Wingen, Kim P C Kuypers, Johannes G Ramaekers, Elia Formisan. Escitalopram Decreases Cross-Regional Functional Connectivity within the Default-Mode Network. PloS one. vol 8. issue 6. 2017-10-11. PMID:23826388. |
the serotonergic (5-ht) neurotransmitter system projects to dmn regions from midbrain efferents, and manipulation of this system could thus reveal insights into the neurobiological mechanisms of dmn functioning. |
2017-10-11 |
2023-08-12 |
human |
| Vincent van de Ven, Marleen Wingen, Kim P C Kuypers, Johannes G Ramaekers, Elia Formisan. Escitalopram Decreases Cross-Regional Functional Connectivity within the Default-Mode Network. PloS one. vol 8. issue 6. 2017-10-11. PMID:23826388. |
here, we investigate intrinsic functional connectivity of the dmn as a function of activity of the serotonergic system, through the administration of the selective serotonin reuptake inhibitor (ssri) escitalopram. |
2017-10-11 |
2023-08-12 |
human |
| Sebastian Pablo Fernandez, Bruno Cauli, Carolina Cabezas, Aude Muzerelle, Jean-Christophe Poncer, Patricia Gaspa. Multiscale single-cell analysis reveals unique phenotypes of raphe 5-HT neurons projecting to the forebrain. Brain structure & function. vol 221. issue 8. 2017-10-10. PMID:26608830. |
overall, these findings allow to define correlated anatomical and physiological identities of serotonin raphe neurons that help understanding how discrete raphe cells subpopulations account for the heterogeneous activities of the midbrain serotonergic system. |
2017-10-10 |
2023-08-13 |
mouse |
| Grzegorz R Juszcza. Disrupted integration of sensory stimuli with information about the movement of the body as a mechanism explaining LSD-induced experience. Medical hypotheses. vol 100. 2017-10-02. PMID:28236857. |
however, despite advanced knowledge about molecular mechanism responsible for the effects induced by lsd and other related substances acting at serotonergic 5-ht |
2017-10-02 |
2023-08-13 |
Not clear |
| Krishna C Vadodaria, Maria C Marchetto, Jerome Mertens, Fred H Gag. Generating human serotonergic neurons in vitro: Methodological advances. BioEssays : news and reviews in molecular, cellular and developmental biology. vol 38. issue 11. 2017-09-20. PMID:27716980. |
remarkably, serotonergic neurons derived from each method robustly produce serotonin, express raphe genes, are electrically active, and respond to selective serotonin reuptake inhibitors in vitro. |
2017-09-20 |
2023-08-13 |
human |
| Charles T Nguyen, Sharon Zhou, William Shanahan, Randi Fai. Lorcaserin in Obese and Overweight Patients Taking Prohibited Serotonergic Agents: A Retrospective Analysis. Clinical therapeutics. vol 38. issue 6. 2017-09-18. PMID:27206567. |
given a theoretic risk for this syndrome in patients administered lorcaserin either alone or in combination with certain serotonergic agents (eg, selective serotonin reuptake inhibitors [ssris] and serotonin-norepinephrine reuptake inhibitors [snris]), patients taking prohibited serotonergic agents were excluded from the phase iii clinical trials. |
2017-09-18 |
2023-08-13 |
Not clear |
| Stephanie B Linley, Francisco Olucha-Bordonau, Robert P Verte. Pattern of distribution of serotonergic fibers to the amygdala and extended amygdala in the rat. The Journal of comparative neurology. vol 525. issue 1. 2017-09-12. PMID:27213991. |
as is well recognized, serotonergic (5-ht) fibers distribute widely throughout the forebrain, including the amygdala. |
2017-09-12 |
2023-08-13 |
rat |
| Anand Kumar Singh, Joanna Zajdel, Elahe Mirrasekhian, Nader Almoosawi, Isabell Frisch, Anna M Klawonn, Maarit Jaarola, Michael Fritz, David Engblo. Prostaglandin-mediated inhibition of serotonin signaling controls the affective component of inflammatory pain. The Journal of clinical investigation. vol 127. issue 4. 2017-09-12. PMID:28287401. |
further, mice lacking the prostaglandin e2 receptor ep3 selectively on serotonergic cells or selectively in the area of the dorsal raphe nucleus failed to form an aversion to formalin-induced pain, as did mice lacking the serotonin transporter. |
2017-09-12 |
2023-08-13 |
mouse |
| Christopher Norris, Michael Loureiro, Cecilia Kramar, Jordan Zunder, Justine Renard, Walter Rushlow, Steven R Laviolett. Cannabidiol Modulates Fear Memory Formation Through Interactions with Serotonergic Transmission in the Mesolimbic System. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 12. 2017-09-11. PMID:27296152. |
cbd has been reported to functionally interact with both the mesolimbic dopamine (da) and serotonergic (5-ht) receptor systems. |
2017-09-11 |
2023-08-13 |
rat |
| Christopher Norris, Michael Loureiro, Cecilia Kramar, Jordan Zunder, Justine Renard, Walter Rushlow, Steven R Laviolett. Cannabidiol Modulates Fear Memory Formation Through Interactions with Serotonergic Transmission in the Mesolimbic System. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 12. 2017-09-11. PMID:27296152. |
these effects were challenged with daergic, cannabinoid cb1 receptor, and serotonergic (5-ht |
2017-09-11 |
2023-08-13 |
rat |
| Andrew F Leuchter, Aimee M Hunter, Felipe A Jain, Molly Tartter, Caroline Crump, Ian A Coo. Escitalopram but not placebo modulates brain rhythmic oscillatory activity in the first week of treatment of Major Depressive Disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27770740. |
serotonin modulates brain oscillatory activity, and serotonergic projections to the thalamus and cortex modulate the frequency of prefrontal rhythmic oscillations. |
2017-09-11 |
2023-08-13 |
human |
| Maarja Haugas, Laura Tikker, Kaia Achim, Marjo Salminen, Juha Partane. Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Development (Cambridge, England). vol 143. issue 23. 2017-09-11. PMID:27789623. |
the newly born serotonergic precursors are segregated into distinct subpopulations expressing vesicular glutamate transporter 3 (vglut3) or serotonin transporter (sert). |
2017-09-11 |
2023-08-13 |
mouse |