| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Claudia Francesca Gasparini, Robert Anthony Smith, Lyn Robyn Griffith. Genetic and biochemical changes of the serotonergic system in migraine pathobiology. The journal of headache and pain. vol 18. issue 1. 2017-04-13. PMID:28194570. |
in this review we present the biology of the serotonergic system and metabolic routes for serotonin and discuss results of biochemical studies with regard to alterations in serotonin in brain, cerebrospinal fluid, saliva, platelets, plasma and urine of migraine patients. |
2017-04-13 |
2023-08-13 |
Not clear |
| Yuko Yoshimura, Chihiro Ishikawa, Haruki Kasegai, Tomoyuki Masuda, Masaaki Yoshikawa, Takashi Shig. Roles of 5-HT Neuroscience research. vol 115. 2017-04-11. PMID:27702575. |
roles of 5-ht the possible interactions between serotonergic and glutamatergic systems during neural development and under the pathogenesis of depression remain unclear. |
2017-04-11 |
2023-08-13 |
Not clear |
| Danilo De Gregorio, Stefano Comai, Luca Posa, Gabriella Gobb. d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology. International journal of molecular sciences. vol 17. issue 11. 2017-03-30. PMID:27886063. |
lsd's mechanism of action is pleiotropic, primarily mediated by the serotonergic system in the dorsal raphe, binding the 5-ht |
2017-03-30 |
2023-08-13 |
Not clear |
| N K Popova, T V Ilchibaeva, V S Naumenk. Neurotrophic Factors (BDNF and GDNF) and the Serotonergic System of the Brain. Biochemistry. Biokhimiia. vol 82. issue 3. 2017-03-22. PMID:28320272. |
the serotonergic (5-ht) system is another major factor in the development and neuroplasticity of the brain. |
2017-03-22 |
2023-08-13 |
Not clear |
| Edoardo Spina, Vincenza Santor. Drug interactions with vortioxetine, a new multimodal antidepressant. Rivista di psichiatria. vol 50. issue 5. 2017-03-21. PMID:26489070. |
like other antidepressants enhancing serotonergic activity, vortioxetine is associated with a potential risk of serotonin syndrome when used in combination with other serotonergic agents. |
2017-03-21 |
2023-08-13 |
human |
| Candice Bailey, Craig Ruaux, Bernadette V Stang, Beth A Valentin. Expression of serotonin, chromogranin-A, serotonin receptor-2B, tryptophan hydroxylase-1, and serotonin reuptake transporter in the intestine of dogs with chronic enteropathy. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. vol 28. issue 3. 2017-03-13. PMID:27026108. |
the objective of our study was to compare expression of several components of the serotonergic system [serotonin (5-ht), serotonin reuptake transporter protein (sert), tryptophan hydroxylase-1 (tph-1), 5-ht receptor2b (5-ht2b)] and the enterochromaffin cell marker chromogranin-a (cga) in the intestinal mucosa between dogs with chronic enteropathy and healthy controls. |
2017-03-13 |
2023-08-13 |
human |
| Kristian Gaarn du Jardin, Heidi Kaastrup Müller, Connie Sanchez, Gregers Wegener, Betina Elfvin. A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex. European journal of pharmacology. vol 786. 2017-03-10. PMID:27235984. |
here, we investigate the effects of ketamine and vortioxetine on gene expression related to serotonergic and glutamatergic neurotransmission as well as neuroplasticity and compare them to those of the selective serotonin reuptake inhibitor fluoxetine. |
2017-03-10 |
2023-08-13 |
rat |
| O Greg Deardorff, Talha Khan, Gaurav Kulkarni, Richard Doisy, Colleen Loeh. Serotonin Syndrome: Prophylactic Treatment With Cyproheptadine. The primary care companion for CNS disorders. vol 18. issue 4. 2017-03-07. PMID:27828700. |
despite the numerous advantages of linezolid therapy, one disadvantage continuing to hinder its use is the risk of serotonin syndrome when coadministered with other serotonergic agents. |
2017-03-07 |
2023-08-13 |
Not clear |
| Ilya Ayzenberg, Ilias Nastos, Katrin Strassburger-Krogias, Mark Obermann, Ralf Gold, Christos Krogia. Hypoechogenicity of brainstem raphe nuclei is associated with increased attack frequency in episodic migraine. Cephalalgia : an international journal of headache. vol 36. issue 8. 2017-03-02. PMID:26566936. |
postulating that migraine may constitute a "chronic low serotonin syndrome," we aimed to evaluate the echogenicity of midbrain structures, including serotonergic brn in episodic migraine. |
2017-03-02 |
2023-08-13 |
Not clear |
| Estelle Ayme-Dietrich, Gaëlle Aubertin-Kirch, Luc Maroteaux, Laurent Monassie. Cardiovascular remodeling and the peripheral serotonergic system. Archives of cardiovascular diseases. vol 110. issue 1. 2017-02-21. PMID:28017279. |
besides the effect of endogenous serotonin, many drugs targeting serotonergic receptors are widely used in the general population (antiobesity agents, antidepressants, antipsychotics, antimigraine agents), and may enhance the cardiovascular risk. |
2017-02-21 |
2023-08-13 |
human |
| Andrea Scharf, Karl-Heinz Gührs, Anna von Mikec. Anti-amyloid compounds protect from silica nanoparticle-induced neurotoxicity in the nematode C. elegans. Nanotoxicology. vol 10. issue 4. 2017-02-13. PMID:26444998. |
the analysis of a reporter worm for serotonergic neural cells revealed that silica np-induced protein aggregation likewise occurs in axons of hsn neurons, where presynaptic accumulation of serotonin, e.g. |
2017-02-13 |
2023-08-13 |
caenorhabditis_elegans |
| Mohammad Hosein Farzaei, Roodabeh Bahramsoltani, Roja Rahimi, Faezeh Abbasabadi, Mohammad Abdollah. A Systematic Review of Plant-Derived Natural Compounds for Anxiety Disorders. Current topics in medicinal chemistry. vol 16. issue 17. 2017-02-01. PMID:26845556. |
the involved mechanisms include interaction with γ-aminobutyric acid (gaba)a receptors at benzodiazepine (bzd) and non-bzd sites with various affinity to different subunits, serotonergic 5-hydrodytryptamine (5-ht)1a and 5-ht2a/c receptors, noradrenergic and dopaminergic systems, glycine and glutamate receptors, and κ-opioid receptor as well as cannabinoid (cb)1 and cb2 receptors. |
2017-02-01 |
2023-08-13 |
human |
| Chang-Hong Wang, Cong Liu, En-Zhao Cong, Gai-Ling Xu, Ting-Ting Lv, Ying-Li Zhang, Qiu-Fen Ning, Ji-Kang Wang, Hui-Yao Nie, Yan L. Association of tryptophan hydroxylase-2 polymorphisms with oppositional defiant disorder in a Chinese Han population. Behavioral and brain functions : BBF. vol 12. issue 1. 2017-01-23. PMID:27871272. |
the enzyme tryptophan hydroxylase-2 (tph-2) synthesizes 5-ht in serotonergic neurons of the midbrain raphe. |
2017-01-23 |
2023-08-13 |
Not clear |
| Ning-Ning Song, Yun-Fang Jia, Lei Zhang, Qiong Zhang, Ying Huang, Xiao-Zhen Liu, Ling Hu, Wei Lan, Ling Chen, Klaus-Peter Lesch, Xiaoyan Chen, Lin Xu, Yu-Qiang Din. Reducing central serotonin in adulthood promotes hippocampal neurogenesis. Scientific reports. vol 6. 2017-01-16. PMID:26839004. |
we used tamoxifen (tm)-induced cre in pet1-creer(t2) mice to either deplete central serotonergic (5-htergic) neurons or inactivate 5-ht synthesis in adulthood and explore the role of central 5-ht in adult hippocampal neurogenesis. |
2017-01-16 |
2023-08-13 |
mouse |
| Nilima Deepak Shah, Ajay B Jai. Serotonin syndrome presenting as pulmonary edema. Indian journal of pharmacology. vol 48. issue 1. 2017-01-09. PMID:26997733. |
serotonin syndrome (ss) is a potentially life-threatening condition resulting from excessive central and peripheral serotonergic activity. |
2017-01-09 |
2023-08-13 |
Not clear |
| Karin E Borgmann-Winter, Hoau-Yan Wang, Rabindranath Ray, Brooke R Willis, Paul J Moberg, Nancy E Rawson, Raquel E Gur, Bruce I Turetsky, Chang-Gyu Hah. Altered G Protein Coupling in Olfactory Neuroepithelial Cells From Patients With Schizophrenia. Schizophrenia bulletin. vol 42. issue 2. 2017-01-02. PMID:26373539. |
increased g protein activation in response to da and 5ht may suggest increased postreceptor da or 5ht signaling as an additional mechanism of dopaminergic or serotonergic dysregulation in schizophrenia. |
2017-01-02 |
2023-08-13 |
human |
| Mary Gemmel, Ine Rayen, Tiffany Lotus, Eva van Donkelaar, Harry W Steinbusch, Sonsoles De Lacalle, Nikolaos Kokras, Christina Dalla, Jodi L Pawlusk. Developmental fluoxetine and prenatal stress effects on serotonin, dopamine, and synaptophysin density in the PFC and hippocampus of offspring at weaning. Developmental psychobiology. vol 58. issue 3. 2017-01-02. PMID:26477449. |
selective serotonin reuptake inhibitor medication exposure during the perinatal period can have a long term impact in adult offspring on neuroplasticity and the serotonergic system, but the impact of these medications during early development is poorly understood. |
2017-01-02 |
2023-08-13 |
rat |
| Peter J Gagolewicz, Hans C Dringenber. Age-Dependent Switch of the Role of Serotonergic 5-HT1A Receptors in Gating Long-Term Potentiation in Rat Visual Cortex In Vivo. Neural plasticity. vol 2016. 2016-12-30. PMID:27247804. |
the rodent primary visual cortex (v1) is densely innervated by serotonergic axons and previous in vitro work has shown that serotonin (5-ht) can modulate plasticity (e.g., long-term potentiation (ltp)) at v1 synapses. |
2016-12-30 |
2023-08-13 |
rat |
| Laura Steenbergen, Bryant J Jongkees, Roberta Sellaro, Lorenza S Colzat. Tryptophan supplementation modulates social behavior: A review. Neuroscience and biobehavioral reviews. vol 64. 2016-12-27. PMID:26987640. |
trp supplementation can increase 5-ht levels in the brain and for this reason numerous studies have investigated whether administration of trp can positively influence social behavior that relies on serotonergic function. |
2016-12-27 |
2023-08-13 |
Not clear |
| Chi-Shun Wu, Show-Hwa Tong, Cheung-Ter Ong, Sheng-Feng Sun. Serotonin Syndrome Induced by Combined Use of Mirtazapine and Olanzapine Complicated with Rhabdomyolysis, Acute Renal Failure, and Acute Pulmonary Edema-A Case Report. Acta neurologica Taiwanica. vol 24. issue 4. 2016-12-23. PMID:27333965. |
serotonin syndrome is a potentially life-threatening complication of serotonergic agents. |
2016-12-23 |
2023-08-13 |
Not clear |