| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masayuki Uchida, Orie Kobayash. Novel effect of α-lactalbumin on the yohimbine-induced hot flush increase of the tail skin temperature in ovariectomized rats. Bioscience, biotechnology, and biochemistry. vol 82. issue 5. 2020-05-25. PMID:29504865. |
then, to clarify the relation between serotonergic and adrenergic nervous systems on the mechanism of hot flush, the effect of paroxetine, 5-ht reuptake inhibitor (ssri) was evaluated on the yohimbine-induced hot flush increase of tail skin temperature in ovariectomized female rats. |
2020-05-25 |
2023-08-13 |
rat |
| Andrew Del Colle, Narek Israelyan, Kara Gross Margoli. Novel aspects of enteric serotonergic signaling in health and brain-gut disease. American journal of physiology. Gastrointestinal and liver physiology. vol 318. issue 1. 2020-05-04. PMID:31682158. |
this review summarizes the current data focusing on the important roles that serotonin plays in ens development and motility, with a focus on novel aspects of serotonergic signaling in medical conditions in which cns and ens co-morbidities are common, including autism spectrum disorders and depression. |
2020-05-04 |
2023-08-13 |
Not clear |
| Motohiro Okada, Ruri Okubo, Kouji Fukuyam. Vortioxetine Subchronically Activates Serotonergic Transmission via Desensitization of Serotonin 5-HT International journal of molecular sciences. vol 20. issue 24. 2020-04-27. PMID:31835640. |
vortioxetine subchronically activates serotonergic transmission via desensitization of serotonin 5-ht vortioxetine is a novel, multimodal antidepressant with unique targets, including the inhibition of the serotonin transporter (set), of serotonin 5-ht |
2020-04-27 |
2023-08-13 |
Not clear |
| Renkai Ge, Ke Chen, Yi Cheng, Yue Da. Morphological and electrophysiological properties of serotonin neurons with NMDA modulation in the mesencephalic locomotor region of neonatal ePet-EYFP mice. Experimental brain research. vol 237. issue 12. 2020-04-24. PMID:31720812. |
this study provided insight into the distribution and properties of 5-ht neurons in the mlr and interaction between serotonergic and glutamatergic modulations. |
2020-04-24 |
2023-08-13 |
mouse |
| Srinivasan Tupal, Carl L Faingol. Fenfluramine, a serotonin-releasing drug, prevents seizure-induced respiratory arrest and is anticonvulsant in the DBA/1 mouse model of SUDEP. Epilepsia. vol 60. issue 3. 2020-04-14. PMID:30719703. |
the serotonin hypothesis of sudep is based on findings that treatments which modify serotonergic function significantly alter susceptibility to seizure-induced sudden death in several epilepsy models, including dba/1 mice. |
2020-04-14 |
2023-08-13 |
mouse |
| Srinivasa P Kommajosyula, Carl L Faingol. Neural activity in the periaqueductal gray and other specific subcortical structures is enhanced when a selective serotonin reuptake inhibitor selectively prevents seizure-induced sudden death in the DBA/1 mouse model of sudden unexpected death in epilepsy. Epilepsia. vol 60. issue 6. 2020-04-10. PMID:31056750. |
the serotonin hypothesis for sudep proposes that modifying serotonergic function significantly alters susceptibility to seizure-induced respiratory arrest (s-ira). |
2020-04-10 |
2023-08-13 |
mouse |
| Srinivasa P Kommajosyula, Carl L Faingol. Neural activity in the periaqueductal gray and other specific subcortical structures is enhanced when a selective serotonin reuptake inhibitor selectively prevents seizure-induced sudden death in the DBA/1 mouse model of sudden unexpected death in epilepsy. Epilepsia. vol 60. issue 6. 2020-04-10. PMID:31056750. |
agents that enhance serotonergic function, including a selective serotonin reuptake inhibitor, fluoxetine, selectively prevent s-ira in dba/1 mice. |
2020-04-10 |
2023-08-13 |
mouse |
| Jianzheng He, Franziska Hommen, Nina Lauer, Sophia Balmert, Henrike Schol. Serotonin transporter dependent modulation of food-seeking behavior. PloS one. vol 15. issue 1. 2020-04-10. PMID:31978073. |
these results provide insights into how serotonin signaling in two serotonergic neurons selectively regulates the behavioral response to key odorants during food seeking. |
2020-04-10 |
2023-08-13 |
drosophila_melanogaster |
| Jo Sourbron, Michèle Partoens, Chloë Scheldeman, Yifan Zhang, Lieven Lagae, Peter de Witt. Drug repurposing for Dravet syndrome in scn1Lab Epilepsia. vol 60. issue 2. 2020-04-08. PMID:30663052. |
it was recently shown that pharmacological modulation of three serotonergic (5-ht) receptors (5-ht |
2020-04-08 |
2023-08-13 |
human |
| Vaughn L Culbertson, Shaikh Emdadur Rahman, Grayson C Bosen, Matthew L Caylor, Dong X. Use of a Bioinformatics-Based Toxicity Scoring System to Assess Serotonin Burden and Predict Population-Level Adverse Drug Events from Concomitant Serotonergic Drug Therapy. Pharmacotherapy. vol 39. issue 2. 2020-03-25. PMID:30620414. |
use of a bioinformatics-based toxicity scoring system to assess serotonin burden and predict population-level adverse drug events from concomitant serotonergic drug therapy. |
2020-03-25 |
2023-08-13 |
Not clear |
| Vaughn L Culbertson, Shaikh Emdadur Rahman, Grayson C Bosen, Matthew L Caylor, Dong X. Use of a Bioinformatics-Based Toxicity Scoring System to Assess Serotonin Burden and Predict Population-Level Adverse Drug Events from Concomitant Serotonergic Drug Therapy. Pharmacotherapy. vol 39. issue 2. 2020-03-25. PMID:30620414. |
numerous medications interact at serotonin (5-hydroxytryptamine [5-ht]) receptors directly or through off-target interactions, causing mild to severe serotonergic adverse drug events (ades), particularly among older adults. |
2020-03-25 |
2023-08-13 |
Not clear |
| Deepthi D'Souza, Monika Sadanand. Stressor during Early Adolescence in Hyperreactive Female Wistar Kyoto Rats Induces a 'Double Hit' Manifested by Variation in Neurobehaviors and Brain Monoamines. Neuroscience. vol 414. 2020-03-13. PMID:31279049. |
medial prefrontal cortex, a still maturing brain area, exhibited increased serotonin (5-ht) metabolite (p < 0.01) and turnover rates (p < 0.01) indicative of altered/maladaptive serotonergic functioning. |
2020-03-13 |
2023-08-13 |
rat |
| Dariusz Zurawek, Piotr Gruca, Lucyna Antkiewicz-Michaluk, Marta Dziedzicka-Wasylewsk. Resilient Phenotype in Chronic Mild Stress Paradigm Is Associated with Altered Expression Levels of miR-18a-5p and Serotonin 5-HT Molecular neurobiology. vol 56. issue 11. 2020-03-12. PMID:31098953. |
resilient phenotype in chronic mild stress paradigm is associated with altered expression levels of mir-18a-5p and serotonin 5-ht disturbed serotonergic signaling in the hippocampus observed in many individuals vulnerable to stress has been suggested as one of the primary factors contributing to the development of depression. |
2020-03-12 |
2023-08-13 |
human |
| Dariusz Zurawek, Piotr Gruca, Lucyna Antkiewicz-Michaluk, Marta Dziedzicka-Wasylewsk. Resilient Phenotype in Chronic Mild Stress Paradigm Is Associated with Altered Expression Levels of miR-18a-5p and Serotonin 5-HT Molecular neurobiology. vol 56. issue 11. 2020-03-12. PMID:31098953. |
all these molecular features may contribute to serotonergic homeostatic balance at the level of serotonin turnover observed in hippocampi of resilient but not stress-vulnerable rats. |
2020-03-12 |
2023-08-13 |
human |
| Chunchen Xiang, Shaojiang Liu, Yutong Fan, Xinyue Wang, Yunbo Jia, Liang Li, Shuyan Cong, Fang Ha. Single nucleotide polymorphisms, variable number tandem repeats and allele influence on serotonergic enzyme modulators for aggressive and suicidal behaviors: A review. Pharmacology, biochemistry, and behavior. vol 180. 2020-03-10. PMID:30928299. |
95 published papers (49 papers for aggression and 46 for suicide) were reviewed to summarize the impact of snps, vntrs, and alleles of tryptophan hydroxylase (tph, the rate-limiting enzyme in serotonin [5-ht] synthesis), 5-ht transporter (5-htt), serotonergic receptors, monoamine oxidase (an enzyme that catalyzes 5-ht degradation) on aggression and suicidal behaviors. |
2020-03-10 |
2023-08-13 |
Not clear |
| Jacob E Montgomery, Sarah Wahlstrom-Helgren, Timothy D Wiggin, Brittany M Corwin, Christina Lillesaar, Mark A Masin. Intraspinal serotonergic signaling suppresses locomotor activity in larval zebrafish. Developmental neurobiology. 2020-03-06. PMID:29923318. |
in the larval zebrafish, intraspinal serotonergic neurons (isns) are a source of spinal 5ht that, despite the availability of numerous genetic and optical tools, has not yet been directly shown to affect the spinal locomotor network. |
2020-03-06 |
2023-08-13 |
zebrafish |
| Silvia Hoirisch-Clapauch, Antonio E Nard. Antidepressants: bleeding or thrombosis? Thrombosis research. vol 181 Suppl 1. 2020-03-03. PMID:31477223. |
there is evidence that serotonergic antidepressants (selective serotonin reuptake inhibitors and serotonin and noradrenaline reuptake inhibitors) restore the fibrinolytic profile. |
2020-03-03 |
2023-08-13 |
Not clear |
| Krishna C Vadodaria, Yuan Ji, Michelle Skime, Apua C Paquola, Timothy Nelson, Daniel Hall-Flavin, Kelly J Heard, Callie Fredlender, Yalin Deng, James Elkins, Komal Dani, Amy T Le, Maria C Marchetto, Richard Weinshilboum, Fred H Gag. Altered serotonergic circuitry in SSRI-resistant major depressive disorder patient-derived neurons. Molecular psychiatry. vol 24. issue 6. 2020-03-02. PMID:30903001. |
disrupted serotonergic neurotransmission has long been implicated in major depressive disorder (mdd), for which selective serotonin reuptake inhibitors (ssris) are the first line of treatment. |
2020-03-02 |
2023-08-13 |
Not clear |
| Florence Evelyne Perrin, Harun Najib Noristan. Serotonergic mechanisms in spinal cord injury. Experimental neurology. vol 318. 2020-03-02. PMID:31085200. |
numerous studies suggest that a chronic increase in serotonergic neurotransmission promotes 5-ht axon sprouting in the intact cns. |
2020-03-02 |
2023-08-13 |
Not clear |
| Florence Evelyne Perrin, Harun Najib Noristan. Serotonergic mechanisms in spinal cord injury. Experimental neurology. vol 318. 2020-03-02. PMID:31085200. |
we then present a comprehensive overview of changes in serotonergic axons after cns damage, and discuss their plasticity upon altered 5-ht neurotransmitter levels. |
2020-03-02 |
2023-08-13 |
Not clear |