Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Luciana S Dorelle, Rodrigo H Da Cuña, Daniela E Sganga, Graciela Rey Vázquez, Laura López Greco, Fabiana L Lo Nostr. Fluoxetine exposure disrupts food intake and energy storage in the cichlid fish Cichlasoma dimerus (Teleostei, Cichliformes). Chemosphere. vol 238. 2020-01-01. PMID:31524604. |
the antidepressant fluoxetine (flx) exerts its effect by inhibiting serotonin (5-ht) reuptake at the presynaptic membrane, thus increasing brain serotonergic activity. |
2020-01-01 |
2023-08-13 |
human |
Nataliya Gorinski, Monika Bijata, Sonal Prasad, Alexander Wirth, Dalia Abdel Galil, Andre Zeug, Daria Bazovkina, Elena Kondaurova, Elizabeth Kulikova, Tatiana Ilchibaeva, Monika Zareba-Koziol, Francesco Papaleo, Diego Scheggia, Gaga Kochlamazashvili, Alexander Dityatev, Ian Smyth, Adam Krzystyniak, Jakub Wlodarczyk, Diethelm W Richter, Tatyana Strekalova, Stephan Sigrist, Claudia Bang, Lisa Hobuß, Jan Fiedler, Thomas Thum, Vladimir S Naumenko, Ghanshyam Pandey, Evgeni Ponimaski. Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors. Nature communications. vol 10. issue 1. 2019-12-30. PMID:31477731. |
the serotonergic system and in particular serotonin 1a receptor (5-ht1ar) are implicated in major depressive disorder (mdd). |
2019-12-30 |
2023-08-13 |
human |
Ottavia Dipasquale, Pierluigi Selvaggi, Mattia Veronese, Anthony S Gabay, Federico Turkheimer, Mitul A Meht. Receptor-Enriched Analysis of functional connectivity by targets (REACT): A novel, multimodal analytical approach informed by PET to study the pharmacodynamic response of the brain under MDMA. NeuroImage. vol 195. 2019-12-20. PMID:30953835. |
this approach enriches the resting state (rs-)fmri analysis with the molecular information about the distribution density of serotonin receptors in the brain, given the serotonergic action of mdma. |
2019-12-20 |
2023-08-13 |
human |
Dino Luethi, Robert Widmer, Daniel Trachsel, Marius C Hoener, Matthias E Liecht. Monoamine receptor interaction profiles of 4-aryl-substituted 2,5-dimethoxyphenethylamines (2C-BI derivatives). European journal of pharmacology. vol 855. 2019-12-20. PMID:31063768. |
many ring-substituted phenethylamines exert psychedelic effects that are thought to be primarily mediated by interactions with serotonergic 5-hydroxytryptamine 2 (5-ht |
2019-12-20 |
2023-08-13 |
Not clear |
Toshinori Hirai, Yutori Ishikawa, Yuya Kawagoe, Yukari Ogawa, Ryuichi Ogawa, Toshimasa Ito. Relationship between Recurrent Falls and Medication Use during Acute-Care Hospitalization: A Retrospective Descriptive Study. Biological & pharmaceutical bulletin. vol 42. issue 7. 2019-12-19. PMID:31257294. |
multivariate logistic regression analysis revealed that selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and noradrenergic and specific serotonergic antidepressants were associated with recurrent falls (odds ratio = 5.98, 95% confidence interval: 1.38-25.9, p = 0.02). |
2019-12-19 |
2023-08-13 |
Not clear |
Toshinori Hirai, Yutori Ishikawa, Yuya Kawagoe, Yukari Ogawa, Ryuichi Ogawa, Toshimasa Ito. Relationship between Recurrent Falls and Medication Use during Acute-Care Hospitalization: A Retrospective Descriptive Study. Biological & pharmaceutical bulletin. vol 42. issue 7. 2019-12-19. PMID:31257294. |
additionally, selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and noradrenergic and specific serotonergic antidepressants were significant risk factors for recurrent falls in women and those aged > 80 years. |
2019-12-19 |
2023-08-13 |
Not clear |
Toshinori Hirai, Yutori Ishikawa, Yuya Kawagoe, Yukari Ogawa, Ryuichi Ogawa, Toshimasa Ito. Relationship between Recurrent Falls and Medication Use during Acute-Care Hospitalization: A Retrospective Descriptive Study. Biological & pharmaceutical bulletin. vol 42. issue 7. 2019-12-19. PMID:31257294. |
selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and noradrenergic and specific serotonergic antidepressants were associated with an increased risk of recurrent falls during hospitalization in an acute-care setting. |
2019-12-19 |
2023-08-13 |
Not clear |
Toshinori Hirai, Yutori Ishikawa, Yuya Kawagoe, Yukari Ogawa, Ryuichi Ogawa, Toshimasa Ito. Relationship between Recurrent Falls and Medication Use during Acute-Care Hospitalization: A Retrospective Descriptive Study. Biological & pharmaceutical bulletin. vol 42. issue 7. 2019-12-19. PMID:31257294. |
clinicians should pay attention to patients receiving selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and noradrenergic and specific serotonergic antidepressants, especially women and aged > 80 years old. |
2019-12-19 |
2023-08-13 |
Not clear |
Liang Xie, Jin Chen, Yong-Min Ding, Xian-Wei Gui, Lan-Xiang Wu, Sheng Tian, Wei W. MicroRNA-26a-2 maintains stress resiliency and antidepressant efficacy by targeting the serotonergic autoreceptor HTR1A. Biochemical and biophysical research communications. vol 511. issue 2. 2019-12-16. PMID:30808545. |
previous research on serotonergic (5-ht) neurons identified microrna-26a (mir-26a) targeting of the serotonin autoreceptor, 5-ht receptor 1a (htr1a). |
2019-12-16 |
2023-08-13 |
mouse |
Miłosz Gołyszny, Ewa Obuchowic. Are neuropeptides relevant for the mechanism of action of SSRIs? Neuropeptides. vol 75. 2019-12-16. PMID:30824124. |
their primary mechanism of action is via influence of the serotonergic (5-ht) system, but a growing amount of data provides evidence for other non-monoaminergic players in ssri effects. |
2019-12-16 |
2023-08-13 |
Not clear |
Giuseppe Romeo, Loredana Salerno, Valeria Pittalà, Marialuisa Candido, Sebastiano Intagliata, Emanuele Amata, Mario Salmona, Alfredo Cagnotto, Antonio Rescifina, Giuseppe Floresta, Maria Nunziata Modic. [1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT European journal of medicinal chemistry. vol 183. 2019-12-16. PMID:31526973. |
[1]benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-ht the present paper describes the synthesis and the binding properties for the serotonergic 5-ht |
2019-12-16 |
2023-08-13 |
Not clear |
Denis A Nikishin, Nina M Alyoshina, Maria L Semenova, Yuri B Shmukle. Analysis of Expression and Functional Activity of Aromatic L-Amino Acid Decarboxylase (DDC) and Serotonin Transporter (SERT) as Potential Sources of Serotonin in Mouse Ovary. International journal of molecular sciences. vol 20. issue 12. 2019-11-29. PMID:31234589. |
the origin of serotonin in the ovary is the key question for understanding mechanisms of serotonergic regulation of reproductive function. |
2019-11-29 |
2023-08-13 |
mouse |
Yoshida, Kobayash. Modulation of the buccal muscle contraction by identified serotonergic and peptidergic neurons in the snail Achatina fulica The Journal of experimental biology. vol 198. issue Pt 3. 2019-11-20. PMID:9318489. |
the serotonergic cerebral neuron v-cdn enhanced b10-evoked contraction of the radula protractor, and it is suggested that this effect is mediated postsynaptically by serotonin released from the v-cdn terminals. |
2019-11-20 |
2023-08-12 |
Not clear |
Kuwasawa, Hil. Evidence for cholinergic inhibitory and serotonergic excitatory neuromuscular transmission in the heart of the bivalve Mercenaria mercenaria The Journal of experimental biology. vol 200. issue Pt 15. 2019-11-20. PMID:9320037. |
this study provides direct electrophysiological evidence for serotonergic ejps and cholinergic ijps, plus immunocytochemical evidence for neural processes containing serotonin, in the myocardium. |
2019-11-20 |
2023-08-12 |
Not clear |
Ursin, Bjorvatn, Sommerfelt, Neckelmann, Bjørku. Studies on sleep/wake effects of serotonin reuptake inhibitors and receptor subtype involvement. Journal of sleep research. vol 1. issue 3. 2019-11-20. PMID:10607045. |
the complex sleep/wake effects following the serotonin uptake inhibitors may result from simultaneous induction of incompatible serotonergic effects. |
2019-11-20 |
2023-08-12 |
rat |
R. Jaffard, E. Mocaer, J-C. Poignant, J. Micheau, A. Marighetto, M. Meunier, D. Béracoché. Effects of tianeptine on spontaneous alternation, simple and concurrent spatial discrimination learning and on alcohol-induced alternation deficits in mice. Behavioural pharmacology. vol 2. issue 1. 2019-11-20. PMID:11224046. |
these data are discussed in light of the effects of tianeptine on serotonergic transmission and of the role of serotonin and acetylcholine in learning and memory processes. |
2019-11-20 |
2023-08-12 |
mouse |
K. Kimura, T. Akai, K. Nakamura, M. Yamaguchi, H. Nakagawa, N. Oshin. Dual activation by lisuride of central serotonin 5-HT(1A) and dopamine D(2) receptor sites: drug discrimination and receptor binding studies. Behavioural pharmacology. vol 2. issue 2. 2019-11-20. PMID:11224054. |
to investigate central serotonergic (5-ht) and dopaminergic (da) actions of lisuride, the discriminative properties of lisuride (0.05mg/kg, i.p.) |
2019-11-20 |
2023-08-12 |
rat |
M. Yamaguchi, K. Kimura-Iwasaki, T. Akai, Y. Nakada, H. Nakagaw. Terguride, a dopamine D(2) partial agonist, as a discriminative stimulus in rats. Behavioural pharmacology. vol 2. issue 3. 2019-11-20. PMID:11224067. |
drug discrimination training with terguride, a 9, 10-transdihydrogenated derivative of lisuride, was carried out using a two-lever food-reinforced procedure (fr 10) in rats, to investigate its influence on central dopaminergic (da) and serotonergic (5-ht) functions. |
2019-11-20 |
2023-08-12 |
rat |
J. Bruhwyler, J.F. Liégeois, E. Chleide, F. Rogister, J. Damas, J. Delarge, M. Mercie. Comparative study of typical neuroleptics, clozapine and newly synthesized clozapine-analogues: correlations between neurochemistry and behaviour. Behavioural pharmacology. vol 3. issue 6. 2019-11-20. PMID:11224158. |
affinity for dopaminergic (d1,d2), serotonergic (5-ht(2)) and cholinergic (muscarinic) receptors were measured and the ratios of these different binding affinities were determined and correlated with the behavioural effects of the drugs in a complex temporal regulation task in the dog. |
2019-11-20 |
2023-08-12 |
dog |
C. Sánche. Effect of serotonergic drugs on footshock-induced ultrasonic vocalization in adult male rats. Behavioural pharmacology. vol 4. issue 3. 2019-11-20. PMID:11224195. |
the effects of 5-ht(1a) receptor agonists with different intrinsic activities and the role of other 5-ht(1) receptor subtypes, and of 5-ht(2) and 5-ht(3) receptors, in mediation of ultrasonic vocalization were studied, as were the effects of increasing serotonergic activity by administration of the 5-ht releaser fenfluramine or the 5-ht precursor 1-5 htp. |
2019-11-20 |
2023-08-12 |
rat |