| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miranda L Groft, Marigny C Normann, Paige R Nicklas, Julia E Jagielo-Miller, Peter J McLaughli. Biphasic effects of 5-HT Naunyn-Schmiedeberg's archives of pharmacology. vol 392. issue 11. 2020-08-20. PMID:31289857. |
biphasic effects of 5-ht the serotonergic 5-ht |
2020-08-20 |
2023-08-13 |
Not clear |
| Florian Javelle, Amit Lampit, Wilhelm Bloch, Peter Häussermann, Sheri L Johnson, Philipp Zimme. Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis. Nutrition reviews. vol 78. issue 1. 2020-08-20. PMID:31504850. |
serotonergic dysfunction, including reduced central serotonin levels, is associated with different psychiatric syndromes, including depression. |
2020-08-20 |
2023-08-13 |
Not clear |
| Shaoping Hou, Tatiana M Saltos, Eugene Mironets, Cameron T Trueblood, Theresa M Connors, Veronica J To. Grafting Embryonic Raphe Neurons Reestablishes Serotonergic Regulation of Sympathetic Activity to Improve Cardiovascular Function after Spinal Cord Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 6. 2020-08-17. PMID:31896670. |
to determine the specific role of reestablishing serotonergic regulation of hemodynamics, we implanted serotonergic (5-ht |
2020-08-17 |
2023-08-13 |
Not clear |
| Eric W Prouty, Daniel J Chandler, Wen-Jun Gao, Barry D Waterhous. Selective vulnerability of dorsal raphe-medial prefrontal cortex projection neurons to corticosterone-induced hypofunction. The European journal of neuroscience. vol 50. issue 1. 2020-08-14. PMID:30687960. |
glucocorticoids regulate the function of serotonergic neurons in the dorsal raphe nucleus (dr), which are the major source of 5-ht to the forebrain. |
2020-08-14 |
2023-08-13 |
rat |
| Eric W Prouty, Daniel J Chandler, Wen-Jun Gao, Barry D Waterhous. Selective vulnerability of dorsal raphe-medial prefrontal cortex projection neurons to corticosterone-induced hypofunction. The European journal of neuroscience. vol 50. issue 1. 2020-08-14. PMID:30687960. |
our results suggest that the serotonergic regulation of cognitive and emotional networks in the mpfc may be more sensitive to the effects of glucocorticoid excess than visual sensory circuits in the lgn and that reduced 5-ht transmission in the mpfc may underlie the association between glucocorticoid excess and depression. |
2020-08-14 |
2023-08-13 |
rat |
| L Holper, D Ben-Shachar, J J Man. Psychotropic and neurological medication effects on mitochondrial complex I and IV in rodent models. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 9. 2020-08-07. PMID:31320210. |
potential contributions to the drug effects were found to be related to the drugs' neurotransmitter receptor profiles with adrenergic (α1b), dopaminergic (d1/2), glutaminergic (nmda1,3), histaminergic (h1), muscarinic (m1,3), opioid (op1-3), serotonergic (5-ht |
2020-08-07 |
2023-08-13 |
Not clear |
| Jin Zhang, Yong Wang, Yi Na Sun, Li Bo Li, Li Zhang, Yuan Guo, Tao Wang, Lu Yao, Li Chen, Jian Li. Blockade of calcium-permeable AMPA receptors in the lateral habenula produces increased antidepressant-like effects in unilateral 6-hydroxydopamine-lesioned rats compared to sham-lesioned rats. Neuropharmacology. vol 157. 2020-07-21. PMID:31251995. |
our findings indicate that blockade of lhb cp-ampars produces antidepressant-like effects, which attribute to decreased firing activity of lhb neurons and increased levels of dopamine and serotonin in the mpfc, and provide further evidence that lhb cp-ampars regulate the firing activity of pvta dopaminergic neurons and mrn serotonergic neurons indirectly via the rmtg. |
2020-07-21 |
2023-08-13 |
rat |
| H J Cassaday, K E Thu. Intraperitoneal 8-OH-DPAT reduces competition from contextual but not discrete conditioning cues. Pharmacology, biochemistry, and behavior. vol 187. 2020-07-21. PMID:31669833. |
the effects of the serotonergic (5-hydroxytryptamine, 5-ht) agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat; 0.2 and 0.4 mg/kg i.p.) |
2020-07-21 |
2023-08-13 |
rat |
| Talia Zeppelin, Lucy Kate Ladefoged, Steffen Sinning, Birgit Schiøt. Substrate and inhibitor binding to the serotonin transporter: Insights from computational, crystallographic, and functional studies. Neuropharmacology. vol 161. 2020-07-14. PMID:30807752. |
sert is essential for regulating serotonergic signaling by the reuptake of serotonin from the synaptic cleft back into the presynaptic neuron. |
2020-07-14 |
2023-08-13 |
Not clear |
| Ameya Sanjay Kasture, Daniela Bartel, Thomas Steinkellner, Sonja Sucic, Thomas Hummel, Michael Freissmut. Distinct contribution of axonal and somatodendritic serotonin transporters in drosophila olfaction. Neuropharmacology. vol 161. 2020-07-14. PMID:30851308. |
the serotonin transporter (sert) regulates serotonergic neurotransmission by retrieving released serotonin and replenishing vesicular stores. |
2020-07-14 |
2023-08-13 |
human |
| Akinori Y Sato, Keisuke Tsunoda, Ryo Mizuyama, Satoshi Shimeg. Serotonin improves behavioral contrast sensitivity of freely moving rats. PloS one. vol 15. issue 3. 2020-06-23. PMID:32191757. |
serotonin (5-ht) is a neuromodulator secreted from serotonergic neurons located in the pons and upper brain stem in a behavioral context-dependent manner. |
2020-06-23 |
2023-08-13 |
rat |
| Louisa J. Steinberg, Mark D. Underwood, Mihran J. Bakalian, Suham A. Kassir, J. John Mann, Victoria Arang. 5-HT1A receptor, 5-HT2A receptor and serotonin transporter binding in the human auditory cortex in depression Journal of psychiatry & neuroscience : JPN. vol 44. issue 5. 2020-06-22. PMID:31120232. |
5-ht1a receptor, 5-ht2a receptor and serotonin transporter binding in the human auditory cortex in depression serotonergic system abnormalities are implicated in many psychiatric disorders, including major depression. |
2020-06-22 |
2023-08-13 |
human |
| Mark A Oyama, Chad Elliott, Kerry A Loughran, Alexander P Kossar, Estibaliz Castillero, Robert J Levy, Giovanni Ferrar. Comparative pathology of human and canine myxomatous mitral valve degeneration: 5HT and TGF-β mechanisms. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. vol 46. 2020-06-22. PMID:32006823. |
one such mechanism involves the neurotransmitter serotonin (5ht), which has been linked to development of valvulopathy in a variety of settings, including valvulopathy induced by serotonergic drugs, serotonin-producing carcinoid tumors, and development of valvulopathy in laboratory animals exposed to high levels of serotonin. |
2020-06-22 |
2023-08-13 |
human |
| Jakob Näslund, Erik Studer, Staffan Nilsson, Elias Eriksso. Expression of 22 serotonin-related genes in rat brain after sub-acute serotonin depletion or reuptake inhibition. Acta neuropsychiatrica. 2020-06-19. PMID:32063244. |
although the assessment of expression of serotonin-related genes in experimental animals has become a common strategy to shed light on variations in brain serotonergic function, it remains largely unknown to what extent the manipulation of serotonin levels causes detectable changes in gene expression. |
2020-06-19 |
2023-08-13 |
rat |
| Hannah C Kinney, Robin L Hayne. The Serotonin Brainstem Hypothesis for the Sudden Infant Death Syndrome. Journal of neuropathology and experimental neurology. vol 78. issue 9. 2020-06-18. PMID:31397480. |
we conclude that an important subset of sids infants has serotonergic abnormalities resulting from a "core lesion" in the medullary reticular formation comprised of nuclei that contain serotonin neurons. |
2020-06-18 |
2023-08-13 |
Not clear |
| C Sevoz-Couche, B H Machado, M Hamon, R Laguzz. The Key Role of Medullary 5-HT3 Receptors in the Serotonin-Mediated Neural Control of Cardiovascular Function. Current neuropharmacology. vol 3. issue 3. 2020-06-18. PMID:32550629. |
in particular, a large body of evidence indicates that serotonin plays a modulatory role in the central control of blood pressure, especially at the level of the nts, which is innervated by both central and peripheral serotonergic fibres. |
2020-06-18 |
2023-08-13 |
Not clear |
| Anna Sophie Thue Hvilsom, Thea P Lillethorup, Peter Iversen, Doris J Doudet, Gregers Wegener, Anne M Landa. Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 4. 2020-06-17. PMID:30826156. |
the serotonergic system plays an important role in depression and alterations in the serotonin transporter (sert) are seen both in depression and response to antidepressant pharmacotherapies. |
2020-06-17 |
2023-08-13 |
rat |
| Xueliang Zuo, Zhiqiang Chen, Juan Cai, Wen Gao, Yao Zhang, Guoyong Han, Liyong Pu, Zhengshan Wu, Wei You, Jianjie Qin, Xinzheng Dai, Hongbing Shen, Jindao Wu, Xuehao Wan. 5-Hydroxytryptamine Receptor 1D Aggravates Hepatocellular Carcinoma Progression Through FoxO6 in AKT-Dependent and Independent Manners. Hepatology (Baltimore, Md.). vol 69. issue 5. 2020-06-15. PMID:30561038. |
nevertheless, the contributions of 5-hydroxytryptamine 1d (5-ht1d), an indispensable member of the serotonergic system, to hepatocellular carcinoma (hcc) remain unknown. |
2020-06-15 |
2023-08-13 |
Not clear |
| Simin Afshar, Siamak Shahidi, Ali Haeri Rohani, Sara Soleimani Asl, Alireza Komak. Protective effects of 5-HT Journal of chemical neuroanatomy. vol 96. 2020-06-15. PMID:30684605. |
involvement of serotonergic systems in ad has been supposed and it is suggested that serotonin receptors modulation may provide a novel therapeutic target for ad. |
2020-06-15 |
2023-08-13 |
Not clear |
| Derya Sargin, Ha-Seul Jeoung, Nathalie M Goodfellow, Evelyn K Lamb. Serotonin Regulation of the Prefrontal Cortex: Cognitive Relevance and the Impact of Developmental Perturbation. ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:31259523. |
extremes of serotonergic modulation alter mood regulation in vulnerable individuals, yet the impact of serotonin under more typical physiological parameters remains unclear. |
2020-06-11 |
2023-08-13 |
Not clear |