Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yong Li, Qian Jiao, Xixun Du, Mingxia Bi, Shuaishuai Han, Lingling Jiao, Hong Jian. Investigation of Behavioral Dysfunctions Induced by Monoamine Depletions in a Mouse Model of Parkinson's Disease. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30135645. |
in addition to the loss of dopaminergic (daergic) neurons, progressive degenerations of noradrenergic (na) and serotonergic (5-ht) neurons were also observed. |
2020-09-30 |
2023-08-13 |
mouse |
Valerie D Phi Van, E Tobias Krause, Loc Phi-Va. Modulation of Fear and Arousal Behavior by Serotonin Transporter (5-HTT) Genotypes in Newly Hatched Chickens. Frontiers in behavioral neuroscience. vol 12. 2020-09-30. PMID:30524254. |
the serotonin transporter (5-htt) plays a key role in regulating serotonergic transmission via removal of serotonin (5-hydroxytryptamine, 5-ht) from synaptic clefts. |
2020-09-30 |
2023-08-13 |
Not clear |
Yashika Bansal, Raghunath Singh, Ishwar Parhar, Anurag Kuhad, Tomoko Sog. Quinolinic Acid and Nuclear Factor Erythroid 2-Related Factor 2 in Depression: Role in Neuroprogression. Frontiers in pharmacology. vol 10. 2020-09-30. PMID:31164818. |
however, due to delayed and/or poor performance of selective serotonin reuptake inhibitors in treating depressive symptoms, the role of the serotonergic system in depression has been recently questioned further. |
2020-09-30 |
2023-08-13 |
Not clear |
Yanan Yang, Dongdong Lin, Chenchang Bao, Huiyang Huang, Haihui Y. Serotonergic Mechanisms of Oocyte Germinal Vesicle Breakdown in the Mud Crab, Frontiers in physiology. vol 10. 2020-09-30. PMID:31275175. |
serotonergic mechanisms of oocyte germinal vesicle breakdown in the mud crab, the mechanism of serotonin (5-ht)-induced oocyte germinal vesicle breakdown (gvbd) in the mud crab, |
2020-09-30 |
2023-08-13 |
Not clear |
Motohiro Okada, Kouji Fukuyama, Ruri Okubo, Takashi Shiroyama, Yuto Ued. Lurasidone Sub-Chronically Activates Serotonergic Transmission via Desensitization of 5-HT1A and 5-HT7 Receptors in Dorsal Raphe Nucleus. Pharmaceuticals (Basel, Switzerland). vol 12. issue 4. 2020-09-30. PMID:31590422. |
these results indicate that acutely lurasidone fails to affect 5-ht release, but chronically enhances serotonergic transmission by desensitizing both 5-ht1ar and 5-ht7r. |
2020-09-30 |
2023-08-13 |
Not clear |
Michelle Hernandez, Michael Walsh, Trilok Stead, Anines Quinones, Latha Gant. Serotonin Syndrome in the Emergency Department. Cureus. vol 11. issue 12. 2020-09-30. PMID:31938599. |
with the widespread use of serotonergic agents including many antidepressants, antiemetics, illicit drugs, and even some herbal supplements, serotonin syndrome is a condition seen more frequently. |
2020-09-30 |
2023-08-13 |
Not clear |
William H. Theodor. Does Serotonin Play a Role in Epilepsy? Epilepsy currents. vol 3. issue 5. 2020-09-29. PMID:15346169. |
studies in experimental models have suggested a potential role for serotonergic transmission in epilepsy, and interest in this research has been increased by the development of positron emission tomography (pet) ligands that can be used to study 5-hydroxytryptamine (5-ht) receptors and transporters. |
2020-09-29 |
2023-08-12 |
Not clear |
Naoko Yamaguchi, Noriaki Nakajima, Shoshiro Okada, Kazunari Yur. Effects of aging on stress-related responses of serotonergic neurons in the dorsal raphe nucleus of male rats. Neurobiology of stress. vol 3. 2020-09-29. PMID:27981176. |
it is known that serotonin, a stress-related transmitter, is closely related with the regulation of stress responses in the brain and that serotonergic function is modulated by various factors, including estrogen, in both sexes. |
2020-09-29 |
2023-08-13 |
rat |
Yuki Higuchi, Tomoko Soga, Ishwar S Parha. Regulatory Pathways of Monoamine Oxidase A during Social Stress. Frontiers in neuroscience. vol 11. 2020-09-29. PMID:29163009. |
social stress has a high impact on many biological systems in the brain, including serotonergic (5-ht) system-a major drug target in the current treatment for depression. |
2020-09-29 |
2023-08-13 |
Not clear |
Jan Rillich, Paul A Stevenso. Serotonin Mediates Depression of Aggression After Acute and Chronic Social Defeat Stress in a Model Insect. Frontiers in behavioral neuroscience. vol 12. 2020-09-29. PMID:30349464. |
we show how 5ht influences aggression in male crickets, before, and after single and multiple defeats using serotonergic drugs, at dosages that had no obvious deleterious effect on general motility: the 5ht synthesis inhibitor alpha-methyltryptophan (amtp), the 5ht |
2020-09-29 |
2023-08-13 |
Not clear |
Yuki C Saito, Natsuko Tsujino, Manabu Abe, Maya Yamazaki, Kenji Sakimura, Takeshi Sakura. Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture. Frontiers in neuroscience. vol 12. 2020-09-29. PMID:30555297. |
orexin neurons send excitatory projections to serotonergic neurons in the dr, which express both subtypes of orexin receptors (mieda et al., 2011), while serotonin (5-ht) potently inhibits orexin neurons through activation of 5ht |
2020-09-29 |
2023-08-13 |
Not clear |
Kai Lin Cham, Tomoko Soga, Ishwar S Parha. Expression of RING Finger Protein 38 in Serotonergic Neurons in the Brain of Nile Tilapia, Frontiers in neuroanatomy. vol 12. 2020-09-29. PMID:30574074. |
expression of ring finger protein 38 in serotonergic neurons in the brain of nile tilapia, serotonin (5-hydroxytryptamine, 5-ht) is one of the major neurotransmitters, modulating diverse behaviours and physiological functions. |
2020-09-29 |
2023-08-13 |
Not clear |
Dubravka Svob Strac, Gordana Nedic Erjavec, Matea Nikolac Perkovic, Korona Nenadic-Sviglin, Marcela Konjevod, Mirko Grubor, Nela Piva. The association between Neuropsychiatric disease and treatment. vol 15. 2020-09-29. PMID:30774345. |
serotonergic changes have been associated with alcoholism, while serotonin receptors type 1b (5-ht1b) play an important role in regulating serotonergic neurotransmission. |
2020-09-29 |
2023-08-13 |
Not clear |
Sang-Seo Park, Tae-Woon Kim, Chang-Ju Kim, Seo-Youn Hong, Bo-Kyun Kim, Young-Je Sim, Mal-Soon Shi. Effect of sildenafil citrate on brain central fatigue after exhaustive swimming exercise in rats. Journal of exercise rehabilitation. vol 15. issue 5. 2020-09-29. PMID:31723552. |
immunohistochemistry for 5-ht, tryptophan hydroxylase (tph), and western blot for serotonergic type 1a (5-ht1 |
2020-09-29 |
2023-08-13 |
rat |
William L Hasle. Newest Drugs for Chronic Unexplained Nausea and Vomiting. Current treatment options in gastroenterology. vol 14. issue 4. 2020-09-28. PMID:27726068. |
recently approved drugs with antiemetic capability include serotonin antagonists with novel modes of delivery and neurokinin antagonists with or without additional serotonergic blocking capabilities. |
2020-09-28 |
2023-08-13 |
Not clear |
Ana P S Dornellas, Valter T Boldarine, Amanda P Pedroso, Lorenza O T Carvalho, Iracema S de Andrade, Tânia M Vulcani-Freitas, Carla C C Dos Santos, Cláudia M da Penha Oller do Nascimento, Lila M Oyama, Eliane B Ribeir. High-Fat Feeding Improves Anxiety-Type Behavior Induced by Ovariectomy in Rats. Frontiers in neuroscience. vol 12. 2020-09-28. PMID:30233288. |
regarding components of hypothalamic serotonergic system, both ovariectomy alone or combined with the fish diet increased 5-ht |
2020-09-28 |
2023-08-13 |
rat |
Michelle Ngai, Douglas A Shoue, Zoe Loh, Mary Ann McDowel. The pharmacological and functional characterization of the serotonergic system in Anopheles gambiae and Aedes aegypti: influences on flight and blood-feeding behavior. Scientific reports. vol 9. issue 1. 2020-09-28. PMID:30872615. |
the serotonergic (5-ht) system has been documented to impact physiological mechanisms involved in disease transmission, suggesting its potential as a new mode of action target for future insecticide development. |
2020-09-28 |
2023-08-13 |
human |
Nissar A Darmani, Denise A Henry, Weixia Zhong, Seetha Chebol. Ultra-low doses of the transient receptor potential vanilloid 1 agonist, resiniferatoxin, prevents vomiting evoked by diverse emetogens in the least shrew (Cryptotis parva). Behavioural pharmacology. vol 31. issue 1. 2020-09-28. PMID:31503071. |
in the current study, we investigated the broad-spectrum antiemetic potential of very low nonemetic doses of rtx against a diverse group of specific emetogens including selective and nonselective agonists of serotonergic 5-hydroxytrptamine (5-ht3) receptor (5-ht and 2-me-5-ht), dopaminergic d2 receptor (apomorphine and quinpirole), cholinergic m1 receptor (pilocarpine and mcn-a-343), as well as the selective substance p neurokinin nk1 receptor agonist gr73632, the selective l-type calcium channel agonist fpl64176, and the sarcoplasmic endoplasmic reticulum calcium atpase (serca) inhibitor thapsigargin. |
2020-09-28 |
2023-08-13 |
Not clear |
Andrey V Bocharov, Alexander N Savostyanov, Sergey S Tamozhnikov, Alexander E Saprigyn, Ekaterina A Proshina, Tatiana N Astakhova, Gennady G Knyaze. Impact of Polymorphisms in the Serotonin Transporter Gene on Oscillatory Dynamics during Inhibition of Planned Movement in Children. Brain sciences. vol 9. issue 11. 2020-09-28. PMID:31698879. |
the serotonin transporter plays an important role in serotonergic neuromodulation. |
2020-09-28 |
2023-08-13 |
human |
Young-Min Par. The Hypothesis on the Prediction of Treatment Response with Buspirone Augmentation along with Serotonergic Antidepressant in Patients with Major Depressive Disorder Using Loudness Dependence of Auditory Evoked Potentials: Two Cases and Review of the Literature for Evidence. Psychiatry investigation. vol 17. issue 3. 2020-09-28. PMID:32151126. |
thus ldaep will be a biological marker for prediction of treatment response with buspirone augmentation with ssri because it can measure central serotonergic activity such as serotonin depletion. |
2020-09-28 |
2023-08-13 |
Not clear |