| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julliet Araújo de Souza, Matilde Cesiana da Silva, Fernanda Cicalese Ourem Costa, Rhowena Jane Barbosa de Matos, Renata Cristinny de Farias Campina, Larissa Cavalcanti do Amaral Almeida, Amanda Alves Marcelino da Silva, Taisy Cinthia Ferro Cavalcante, Gabriel Araújo Tavares, Sandra Lopes de Souz. Early life stress induced by maternal separation during lactation alters the eating behavior and serotonin system in middle-aged rat female offspring. Pharmacology, biochemistry, and behavior. vol 192. 2021-01-22. PMID:32199909. |
as this system modulates the feeding behavior, the present study aimed at investigating the effects of maternal separation-induced stress on both the feeding behavior and serotonergic system of the middle-aged female rats by manipulating this system using fluoxetine, a selective serotonin transporter inhibitor. |
2021-01-22 |
2023-08-13 |
rat |
| J J van der Zande, M Joling, I G Happach, C Vriend, Ph Scheltens, J Booij, A W Lemstr. Serotonergic deficits in dementia with Lewy bodies with concomitant Alzheimer's disease pathology: An NeuroImage. Clinical. vol 25. 2021-01-11. PMID:31790878. |
serotonergic deficits in dementia with lewy bodies with concomitant alzheimer's disease pathology: an to study the influence of concomitant alzheimer's disease (ad) pathology in dementia with lewy bodies (dlb) on dopamine transporter (dat) and serotonin transporter (sert) availability, using |
2021-01-11 |
2023-08-13 |
Not clear |
| Nina C Donner, Sofia M Davies, Stephanie D Fitz, Drake M Kienzle, Anantha Shekhar, Christopher A Lowr. Crh receptor priming in the bed nucleus of the stria terminalis (BNST) induces tph2 gene expression in the dorsomedial dorsal raphe nucleus and chronic anxiety. Progress in neuro-psychopharmacology & biological psychiatry. vol 96. 2021-01-04. PMID:31415826. |
since the bnst projects heavily to the dorsal raphe nucleus (dr), the main source of brain serotonin, we here tested the hypothesis that such repeated, anxiety-inducing activation of crh receptors in the bnst alters the expression of serotonergic genes in the dr, including tph2, the gene encoding the rate-limiting enzyme for brain serotonin synthesis, and slc6a4, the gene encoding the serotonin transporter (sert). |
2021-01-04 |
2023-08-13 |
rat |
| Mirko Grubor, Maja Zivkovic, Marina Sagud, Matea Nikolac Perkovic, Alma Mihaljevic-Peles, Nela Pivac, Dorotea Muck-Seler, Dubravka Svob Stra. International journal of molecular sciences. vol 21. issue 7. 2021-01-04. PMID:32231051. |
in addition to the dopaminergic system, serotonergic mechanisms, including serotonin (5-ht) receptors, might be involved in eps development. |
2021-01-04 |
2023-08-13 |
Not clear |
| Hatylas Azevedo, Marcos Ferreira, Alessandra Mascarello, Pavel Osten, Cristiano Ruch Werneck Guimarãe. The serotonergic and alpha-1 adrenergic receptor modulator ACH-000029 ameliorates anxiety-like behavior in a post-traumatic stress disorder model. Neuropharmacology. vol 164. 2020-12-31. PMID:31843397. |
the serotonergic (5-ht) and noradrenergic (ne) systems are deeply involved in the pathogenesis of ptsd. |
2020-12-31 |
2023-08-13 |
mouse |
| Briana K Chen, Indira Mendez-David, Victor M Luna, Charlène Faye, Alain M Gardier, Denis J David, Christine A Denn. Prophylactic efficacy of 5-HT Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 3. 2020-12-28. PMID:31600767. |
while we have shown that the selective 5-hydroxytryptamine (5-ht) (serotonin) reuptake inhibitor (ssri) fluoxetine (flx) is ineffective as a prophylactic, we hypothesized that other serotonergic compounds such as serotonin 4 receptor (5-ht |
2020-12-28 |
2023-08-13 |
Not clear |
| Yuri Nishimura, Kaori Mabuchi, Natsumi Omura, Ayako Igarashi, Megumi Miura, Nanako Mima, Hiroko Negishi, Keiko Morimoto, Akira Takamat. Fluoxetine Mimics the Anorectic Action of Estrogen and Its Regulation of Circadian Feeding in Ovariectomized Female Rats. Nutrients. vol 12. issue 3. 2020-12-28. PMID:32235766. |
here, we hypothesized that serotonergic neurons in the central nervous system (cns), which have anorectic action and play a role in regulating circadian rhythm, mediate the light phase-specific anorectic action of estrogen, and that selective serotonin reuptake inhibitors (ssris) mimic the hypophagic action of estrogen. |
2020-12-28 |
2023-08-13 |
rat |
| Natalia M Biserova, Janetta V Korneva, Tatiana A Polyakov. The brain structure of selected trypanorhynch tapeworms. Journal of morphology. vol 281. issue 8. 2020-12-10. PMID:32603536. |
highly developed serotonergic neuropils are present in the anterior and lateral lobes; numerous 5-ht neurons are found in the brain lobes including the central unpaired lobe. |
2020-12-10 |
2023-08-13 |
Not clear |
| M G Marrero, S L Field, A L Skibiel, B Dado-Senn, J P Driver, J Laport. Increasing serotonin bioavailability alters gene expression in peripheral leukocytes and lymphoid tissues of dairy calves. Scientific reports. vol 10. issue 1. 2020-12-08. PMID:32546841. |
we hypothesized that increased serotonin bioavailability promotes serotonergic signaling and modulates the expression of immune related genes in peripheral leukocytes and immune-related tissues of dairy calves. |
2020-12-08 |
2023-08-13 |
human |
| Aleyda M San Hernandez, Chetana Singh, Danel J Valero, Javariya Nisar, Jose I Trujillo Ramirez, Karisma K Kothari, Sasank Isola, Domonick K Gordo. Multiple Sclerosis and Serotonin: Potential Therapeutic Applications. Cureus. vol 12. issue 11. 2020-12-07. PMID:33274166. |
due to a high prevalence of psychiatric comorbidities and proven abnormalities in serotonin (5-ht) levels among ms patients, they are usually on drugs that modify the serotonergic system. |
2020-12-07 |
2023-08-13 |
human |
| Monica Lima-Maximino, Maryana Pereira Pyterson, Rhayra Xavier do Carmo Silva, Gabriela Cristini Vidal Gomes, Sueslene Prado Rocha, Anderson Manoel Herculano, Denis Broock Rosemberg, Caio Maximin. Phasic and tonic serotonin modulate alarm reactions and post-exposure behavior in zebrafish. Journal of neurochemistry. vol 153. issue 4. 2020-10-28. PMID:32031241. |
this paradoxical, dual role of 5-ht suggests that a serotonergic tone inhibits fear responses, while an acute increase in 5-ht would produce anxiety-like behavior. |
2020-10-28 |
2023-08-13 |
zebrafish |
| Dehuti Pandya, My Tran, Monica Verduzco-Gutierre. Clinical Relevance of Pharmacogenetics in Serotonin Syndrome. Case reports in psychiatry. vol 2020. 2020-10-28. PMID:33101751. |
serotonin syndrome is a predictable life-threatening condition that is caused by serotonergic stimulation of the central and peripheral nervous systems. |
2020-10-28 |
2023-08-13 |
Not clear |
| Dehuti Pandya, My Tran, Monica Verduzco-Gutierre. Clinical Relevance of Pharmacogenetics in Serotonin Syndrome. Case reports in psychiatry. vol 2020. 2020-10-28. PMID:33101751. |
his medication list consisted of low-dose serotonergic agents, which is unusual as most cases of serotonin syndrome involve higher doses. |
2020-10-28 |
2023-08-13 |
Not clear |
| Dehuti Pandya, My Tran, Monica Verduzco-Gutierre. Clinical Relevance of Pharmacogenetics in Serotonin Syndrome. Case reports in psychiatry. vol 2020. 2020-10-28. PMID:33101751. |
a review of his pharmacogenetic profile is presented to retrospectively evaluate the additive risk for serotonin syndrome and implications on resuming serotonergic agents. |
2020-10-28 |
2023-08-13 |
Not clear |
| Meiju Zhu, Hongzhu Zhu, Xiaomin Ding, Shaosheng Liu, Yuanhua Zo. Analysis of the anti-fatigue activity of polysaccharides from Spirulina platensis: role of central 5-hydroxytryptamine mechanisms. Food & function. vol 11. issue 2. 2020-10-19. PMID:32057057. |
this study evaluated the effects of polysaccharides from spirulina platensis (psp) on endurance during treadmill exercise; levels of some biochemical indicators including hemoglobin (hb), lactic acid (la), creatine kinase (ck), and blood urea nitrogen (bun); concentrations of 5-hydroxytryptamine (5-ht); and expressions of second isoforms of tryptophan hydroxylase (tph2) and serotonergic type 1b inhibitory autoreceptor (5-ht1b) in the caudate putamen of exercising rats. |
2020-10-19 |
2023-08-13 |
rat |
| Verena Buchecker, Ann-Marie Waldron, R Maarten van Dijk, Ines Koska, Matthias Brendel, Barbara von Ungern-Sternberg, Simon Lindner, Franz Josef Gildehaus, Sibylle Ziegler, Peter Bartenstein, Heidrun Potschk. [ EJNMMI research. vol 10. issue 1. 2020-10-16. PMID:32990819. |
[ stress exposure can significantly affect serotonergic signaling with a particular impact on 5-ht |
2020-10-16 |
2023-08-13 |
Not clear |
| Chun-Hsien Chu, Jia-Shing Chen, Pei-Chin Chuang, Chia-Hao Su, Ya-Ling Chan, Ying-Ju Yang, Yu-Ting Chiang, Yu-Ya Su, Po-Wu Gean, H Sunny Su. TIAM2S as a novel regulator for serotonin level enhances brain plasticity and locomotion behavior. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 2. 2020-10-06. PMID:31908036. |
moreover, tiam2s overexpressing tg mice show increased number and length of serotonergic fibers at early postnatal stage, results in higher serotonin levels at both the serum and brain regions, and higher neuroplasticity and hyperlocomotion in latter adulthood. |
2020-10-06 |
2023-08-13 |
mouse |
| Bart A Ellenbroek, Caren August, Jiun You. Does Prenatal Valproate Interact with a Genetic Reduction in the Serotonin Transporter? A Rat Study on Anxiety and Cognition. Frontiers in neuroscience. vol 10. 2020-10-01. PMID:27708559. |
given that vpa significantly impacts on the serotonergic system, and serotonin has strong biochemical and genetic links to asd, we aimed to investigate the interaction between genetic reduction in the serotonin transporter and prenatal valproate administration. |
2020-10-01 |
2023-08-13 |
mouse |
| Dipen Dineshkumar Patel, David Galarnea. Serotonin Syndrome With Fluoxetine: Two Case Reports. The Ochsner journal. vol 16. issue 4. 2020-10-01. PMID:27999518. |
serotonin syndrome is a rare but serious complication of treatment with serotonergic agents. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ryoko Hiroi, Giulia Weyrich, Stephanie V Koebele, Sarah E Mennenga, Joshua S Talboom, Lauren T Hewitt, Courtney N Lavery, Perla Mendoza, Ambra Jordan, Heather A Bimonte-Nelso. Benefits of Hormone Therapy Estrogens Depend on Estrogen Type: 17β-Estradiol and Conjugated Equine Estrogens Have Differential Effects on Cognitive, Anxiety-Like, and Depressive-Like Behaviors and Increase Tryptophan Hydroxylase-2 mRNA Levels in Dorsal Raphe Nucleus Subregions. Frontiers in neuroscience. vol 10. 2020-10-01. PMID:28008302. |
serotonergic neurons in the dorsal raphe nucleus (drn) are a major source of 5-ht in the forebrain and play a critical role in regulation of stress-related disorders. |
2020-10-01 |
2023-08-13 |
rat |