| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryo Kikuoka, Ikuko Miyazaki, Natsuki Kubota, Megumi Maeda, Daiki Kagawa, Masaaki Moriyama, Asuka Sato, Shinki Murakami, Yoshihisa Kitamura, Toshiaki Sendo, Masato Asanum. Mirtazapine exerts astrocyte-mediated dopaminergic neuroprotection. Scientific reports. vol 10. issue 1. 2021-03-18. PMID:33244123. |
mirtazapine, a noradrenergic and specific serotonergic antidepressant (nassa), is known to activate serotonin (5-ht) 1a receptor. |
2021-03-18 |
2023-08-13 |
mouse |
| Rafael Guimarães Dos Santos, José Carlos Bouso, Juliana Mendes Rocha, Giordano Novak Rossi, Jaime E Halla. The Use of Classic Hallucinogens/Psychedelics in a Therapeutic Context: Healthcare Policy Opportunities and Challenges. Risk management and healthcare policy. vol 14. 2021-03-13. PMID:33707976. |
psychedelics or serotonergic hallucinogens are a group of substances that share the agonism of serotonergic 5-ht |
2021-03-13 |
2023-08-13 |
Not clear |
| Ching-Yi Lin, Alexander Sparks, Yu-Shang Le. Improvement of lower urinary tract function by a selective serotonin 5-HT Experimental neurology. vol 332. 2021-03-09. PMID:32615138. |
experimental studies in animals have shown a dense innervation of serotonergic (5-ht) fibers and multiple 5-ht receptors in the spinal reflex circuits that control voiding function. |
2021-03-09 |
2023-08-13 |
rat |
| Karl-Jürgen Bär, Stefanie Köhler, Feliberto de la Cruz, Andy Schumann, Florian D Zepf, Gerd Wagne. Functional consequences of acute tryptophan depletion on raphe nuclei connectivity and network organization in healthy women. NeuroImage. vol 207. 2021-03-03. PMID:31743788. |
the aim was to perturb 5-ht synthesis and to detect its impact on brain functional connectivity (fc) of the upper serotonergic raphe nuclei, the amygdala and the ventromedial prefrontal cortex as well as on network organization using resting state fmri. |
2021-03-03 |
2023-08-13 |
human |
| Balasubramaniam Annamalai, Durairaj Ragu Varman, Rebecca E Horton, Lynette C Daws, Lankupalle D Jayanthi, Sammanda Ramamoorth. Histamine Receptors Regulate the Activity, Surface Expression, and Phosphorylation of Serotonin Transporters. ACS chemical neuroscience. vol 11. issue 3. 2021-03-03. PMID:31916747. |
reuptake and clearance of released serotonin (5-ht) are critical in serotonergic neurotransmission. |
2021-03-03 |
2023-08-13 |
Not clear |
| Gabriel Araújo Tavares, Larissa Cavalcanti do Amaral Almeida, Julliet Araújo de Souza, Felipe Leitão de Souza, Glauber Rudá Feitosa Braz, Bruna Times Silva, Andresa Mayara da Silva Santos, Cláudia Jacques Lagranha, Sandra Lopes de Souz. Early weaning modulates eating behavior and promotes hypofunction of the serotonergic (5HT) system in juvenile male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 80. issue 3. 2021-03-03. PMID:32083748. |
early weaning modulates eating behavior and promotes hypofunction of the serotonergic (5ht) system in juvenile male rats. |
2021-03-03 |
2023-08-13 |
rat |
| Hager Tabka, Amani Cheikh, Sonia Maatoug, Mohamed El Ayeb, Saïd Bendahhou, Rym Benkhalif. First Evidence of Kv3.1b Potassium Channel Subtype Expression during Neuronal Serotonergic 1C11 Cell Line Development. International journal of molecular sciences. vol 21. issue 19. 2021-03-01. PMID:33003279. |
to define the relationship between kv3.1 and serotonin receptors (sr) pharmacological modulation, we showed that 1c11, a serotonergic cell line, expresses different voltage gated potassium (vgk) channels subtypes in the presence (differentiated cells (1c11d)) or absence (not differentiated cells (1c11nd)) of induction. |
2021-03-01 |
2023-08-13 |
Not clear |
| Chen Li, Nicholas McCloskey, Jared Phillips, Steven J Simmons, Lynn G Kirb. CRF-5-HT interactions in the dorsal raphe nucleus and motivation for stress-induced opioid reinstatement. Psychopharmacology. vol 238. issue 1. 2021-02-26. PMID:33231727. |
our previous data show that stressors can inhibit 5-ht neuronal activity and release by stimulating the release of the stress neurohormone corticotropin-releasing factor (crf) within the serotonergic dorsal raphe nucleus (drn). |
2021-02-26 |
2023-08-13 |
Not clear |
| Anna Kwaśniewska, Krzysztof Miazga, Henryk Majczyński, Larry M Jordan, Małgorzata Zawadzka, Urszula Sławińsk. Noradrenergic Components of Locomotor Recovery Induced by Intraspinal Grafting of the Embryonic Brainstem in Adult Paraplegic Rats. International journal of molecular sciences. vol 21. issue 15. 2021-02-22. PMID:32752261. |
intraspinal grafting of serotonergic (5-ht) neurons was shown to restore plantar stepping in paraplegic rats. |
2021-02-22 |
2023-08-13 |
rat |
| Jessica L Armstrong, Austen B Casey, Tanishka S Saraf, Munmun Mukherjee, Raymond G Booth, Clinton E Cana. ( ACS pharmacology & translational science. vol 3. issue 3. 2021-02-21. PMID:32566916. |
serotonergic neurons directly innervate and modulate the activity of neurobiological circuits altered in both disorders, providing a rationale for investigating serotonin receptors (5-htrs) as targets for fxs and asd drug discovery. |
2021-02-21 |
2023-08-13 |
Not clear |
| Dieu Hien Phan, Eun-Joo Shin, Naveen Sharma, Tran Phi Hoang Yen, Duy-Khanh Dang, Yong Sup Lee, Yu Jeung Lee, Seung-Yeol Nah, Jae Hoon Cheong, Ji Hoon Jeong, Hyoung-Chun Ki. 5-HT Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 141. 2021-02-19. PMID:32437895. |
5-ht p-chloroamphetamine (pca), an amphetamine derivative, has been shown to induce serotonergic toxicity. |
2021-02-19 |
2023-08-13 |
Not clear |
| Mariana M Marquez, Maurice J Chacro. Serotonin modulates optimized coding of natural stimuli through increased neural and behavioural responses via enhanced burst firing. The Journal of physiology. vol 598. issue 8. 2021-02-15. PMID:32011728. |
the function of serotonergic fibres onto sensory areas remains poorly understood we show that serotonin application enhances sensory neural and behavioural responses to second order stimuli enhanced neural responses most likely occurred because of increased burst firing changes in neural sensitivity due to burst firing were the best predictor of changes in behavioural sensitivity our results suggest that serotonin optimizes coding of stimuli encountered during aggression. |
2021-02-15 |
2023-08-13 |
Not clear |
| Concepció Marin, Mercè Bonastre, Mireya Fuentes, Joaquim Mullo. Lack of correlation between dyskinesia and pallidal serotonin transporter expression-induced by L-Dopa and Pramipexole in hemiparkinsonian rats. Pharmacology, biochemistry, and behavior. vol 197. 2021-02-08. PMID:32750392. |
the role of pallidal serotonergic terminals in the development of l-dopa-induced dyskinesias (lids) in parkinson's disease (pd) has been recently highlighted correlating pallidal serotonin transporter (sert) expression levels with dyskinesias severity. |
2021-02-08 |
2023-08-13 |
rat |
| Concepció Marin, Mercè Bonastre, Mireya Fuentes, Joaquim Mullo. Lack of correlation between dyskinesia and pallidal serotonin transporter expression-induced by L-Dopa and Pramipexole in hemiparkinsonian rats. Pharmacology, biochemistry, and behavior. vol 197. 2021-02-08. PMID:32750392. |
however, the role of external globus pallidus (gpe, gp in rodents) serotonergic function in lids is still controversial since several studies have shown no differences in gpe serotonin (ser) and sert levels between dyskinetic and non-dyskinetic pd patients. |
2021-02-08 |
2023-08-13 |
rat |
| Angel Carvajal-Oliveros, Jorge M Campusan. Studying the Contribution of Serotonin to Neurodevelopmental Disorders. Can This Fly? Frontiers in behavioral neuroscience. vol 14. 2021-01-30. PMID:33510625. |
it has been proposed that given the complex and numerous actions of serotonin, animal models could better serve to study the complexity of serotonin actions, while providing insights on how hindering serotonergic signaling could contribute to brain disorders. |
2021-01-30 |
2023-08-13 |
Not clear |
| Gholamali Dorooshi, Shafeajafar Zoofaghari, Rokhsareh Meama. Serotonin Toxicity Following Suicide with Citalopram and Lamotrigine: A Rare Case Report and Literature Review. Journal of research in pharmacy practice. vol 9. issue 3. 2021-01-26. PMID:33489986. |
in most cases, a combination of two or more serotonergic drugs can cause serotonin syndrome. |
2021-01-26 |
2023-08-13 |
Not clear |
| Gholamali Dorooshi, Shafeajafar Zoofaghari, Rokhsareh Meama. Serotonin Toxicity Following Suicide with Citalopram and Lamotrigine: A Rare Case Report and Literature Review. Journal of research in pharmacy practice. vol 9. issue 3. 2021-01-26. PMID:33489986. |
lamotrigine, especially in combination with other serotonergic drugs, should be considered a cause of serotonin toxicity. |
2021-01-26 |
2023-08-13 |
Not clear |
| S Schreiber, C G Pic. Trazodone and mirtazapine: A possible opioid involvement in their use (at low dose) for sleep? Medical hypotheses. vol 136. 2021-01-25. PMID:31759303. |
the mostly prescribed antidepressants for sleep are trazodone (a weak, but specific inhibitor of the synaptosomal uptake of serotonin, that also binds to alpha-1 and alpha-2 adrenoreceptor sites) and mirtazapine (a postsynaptic drug which enhances noradrenergic and 5-ht1a-mediated serotonergic neurotransmission via antagonism of central alpha-2-auto- and hetero-adrenoreceptors). |
2021-01-25 |
2023-08-13 |
mouse |
| S Schreiber, C G Pic. Trazodone and mirtazapine: A possible opioid involvement in their use (at low dose) for sleep? Medical hypotheses. vol 136. 2021-01-25. PMID:31759303. |
summing up the various interactions of trazodone and mirtazapine with opioid, noradrenergic and serotonergic agonists and antagonists, we found that the antinociceptive effect of trazodone is influenced by the opioid receptor subtypes mu and delta (and a clear 5-ht mechanism of antinociception), while the antinociceptive effect of mirtazapine is mainly influenced by kappa and mu opioid receptor subtype (combined with both serotonergic and noradrenergic receptors). |
2021-01-25 |
2023-08-13 |
mouse |
| J M Carpenter, H E Gordon, H D Ludwig, J J Wagner, D A Harn, T Norberg, N M Filipo. Neurochemical and neuroinflammatory perturbations in two Gulf War Illness models: Modulation by the immunotherapeutic LNFPIII. Neurotoxicology. vol 77. 2021-01-22. PMID:31866310. |
serotonergic (5-ht) and dopaminergic (da) dyshomeostasis caused by gwi chemicals was apparent in multiple brain regions, primarily in the nucleus accumbens (5-ht) and hippocampus (5-ht, da) for both models. |
2021-01-22 |
2023-08-13 |
mouse |