| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hera Wu, DeVon Herr, Nancie J MacIver, Jeffrey C Rathmell, Valerie A Gerriet. CD4 T cells differentially express cellular machinery for serotonin signaling, synthesis, and metabolism. International immunopharmacology. vol 88. 2021-05-25. PMID:32866787. |
5-ht is well known as a neurotransmitter and recently has been recognized to play a role in the immune response; however, little is known about the immune cell type-specific expression of the serotonergic machinery and receptors. |
2021-05-25 |
2023-08-13 |
Not clear |
| Irmak Sah, Emel Hulya Yukseloglu, Nese Kocabasoglu, Burcu Bayoglu, Emre Cirakoglu, Mujgan Cengi. The effects of 5-HTTLPR/rs25531 serotonin transporter gene polymorphisms on antisocial personality disorder among criminals in a sample of the Turkish population. Molecular biology reports. vol 48. issue 1. 2021-05-25. PMID:33452587. |
it has been determined by previous studies that aspd may have a genetic origin and the human serotonin transporter gene (slc6a4) is one of the two serotonergic genes expected to be associated with this disorder. |
2021-05-25 |
2023-08-13 |
human |
| Omar Al-Radideh, Kok Hoe Chan, Shawn Gupta, Jihad Slim, Sharath Bellar. Concurrent Serotonin Syndrome and Prolong QT Interval Induced by Paroxetine Overdose With Isotretinoin. Cureus. vol 13. issue 4. 2021-05-20. PMID:34007750. |
the use of serotonergic drugs has increased in the last decade especially selective serotonin reuptake inhibitors (ssris) with increased indications. |
2021-05-20 |
2023-08-13 |
Not clear |
| Omar Al-Radideh, Kok Hoe Chan, Shawn Gupta, Jihad Slim, Sharath Bellar. Concurrent Serotonin Syndrome and Prolong QT Interval Induced by Paroxetine Overdose With Isotretinoin. Cureus. vol 13. issue 4. 2021-05-20. PMID:34007750. |
serotonin syndrome (ss) and qt prolongation are serious adverse reactions of ssri use, they usually occur with concomitant use of two or more serotonergic medication. |
2021-05-20 |
2023-08-13 |
Not clear |
| Subramanian Thangaleela, Durairaj Ragu Varman, Karunanithi Sivasangari, Koilmani Emmanuvel Raja. Inhibition of monoamine oxidase attenuates social defeat-induced memory impairment in goldfish, (Carassius auratus): A possible involvement of synaptic proteins and BDNF. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 239. 2021-05-19. PMID:32805442. |
taken together, our results suggest that mao is an essential component in the serotonergic system that finely tunes the level of 5-ht, which further regulates the molecules involving in synaptic transmission, synaptic plasticity and memory. |
2021-05-19 |
2023-08-13 |
Not clear |
| Simli Dey, Dayana Surendran, Oskar Engberg, Ankur Gupta, Sashaina E Fanibunda, Anirban Das, Barun Kumar Maity, Arpan Dey, Vicky Visvakarma, Mamata Kallianpur, Holger A Scheidt, Gilbert Walker, Vidita A Vaidya, Daniel Huster, Sudipta Mait. Altered Membrane Mechanics Provides a Receptor-Independent Pathway for Serotonin Action. Chemistry (Weinheim an der Bergstrasse, Germany). vol 27. issue 27. 2021-05-19. PMID:33502812. |
in the rn46a immortalized serotonergic neuronal cell line, extracellular serotonin enhances transferrin receptor endocytosis, even in the presence of broad-spectrum serotonin receptor and transporter inhibitors. |
2021-05-19 |
2023-08-13 |
Not clear |
| Tajana Ljubin-Golub, Suzana Uzun, Ninoslav Mimica, Oliver Kozumplik, Dubravka Kalinic, Zrnka Kovacic Petrovic, Petra Folnegovic Grosic, Nela Piva. Platelet serotonin concentration and trait aggression in veterans with post-traumatic stress disorder: a preliminary study. Stress (Amsterdam, Netherlands). 2021-05-19. PMID:34006175. |
serotonergic (5-ht) dysfunction is associated with post-traumatic stress disorder (ptsd), but also with increased aggression and impulsivity, hallmarks of ptsd. |
2021-05-19 |
2023-08-13 |
human |
| Yu Miyahara, Hideki Funahashi, Rumi Naono-Nakayama, Ayaka Haruta-Tsukamoto, Chiyo Muroi, Yoichiro Kogoh, Toshikazu Nishimori, Yasushi Ishid. Serotonin and noradrenaline modulate chronic itch processing in mice. European journal of pharmacology. vol 883. 2021-05-18. PMID:32619678. |
a pretreatment with milnacipran, a serotonin and noradrenaline reuptake inhibitor, and mirtazapine, a noradrenergic and specific serotonergic antidepressant, attenuated the induction of spontaneous scratching behavior in mice with chronic itch. |
2021-05-18 |
2023-08-13 |
mouse |
| Elizabeth K Unger, Jacob P Keller, Michael Altermatt, Ruqiang Liang, Aya Matsui, Chunyang Dong, Olivia J Hon, Zi Yao, Junqing Sun, Samba Banala, Meghan E Flanigan, David A Jaffe, Samantha Hartanto, Jane Carlen, Grace O Mizuno, Phillip M Borden, Amol V Shivange, Lindsay P Cameron, Steffen Sinning, Suzanne M Underhill, David E Olson, Susan G Amara, Duncan Temple Lang, Gary Rudnick, Jonathan S Marvin, Luke D Lavis, Henry A Lester, Veronica A Alvarez, Andrew J Fisher, Jennifer A Prescher, Thomas L Kash, Vladimir Yarov-Yarovoy, Viviana Gradinaru, Loren L Looger, Lin Tia. Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning. Cell. vol 183. issue 7. 2021-05-18. PMID:33333022. |
existing drugs have limited efficacy; creation of improved versions will require better understanding of serotonergic circuitry, which has been hampered by our inability to monitor serotonin release and transport with high spatial and temporal resolution. |
2021-05-18 |
2023-08-13 |
mouse |
| Hanne Demant Hansen, Ulrich Lindberg, Brice Ozenne, Patrick MacDonald Fisher, Annette Johansen, Claus Svarer, Sune Høgild Keller, Adam Espe Hansen, Gitte Moos Knudse. Visual stimuli induce serotonin release in occipital cortex: A simultaneous positron emission tomography/magnetic resonance imaging study. Human brain mapping. vol 41. issue 16. 2021-05-17. PMID:32813903. |
endogenous serotonin (5-ht) release can be measured noninvasively using positron emission tomography (pet) imaging in combination with certain serotonergic radiotracers. |
2021-05-17 |
2023-08-13 |
Not clear |
| Mala Ananth, Elizabeth A Bartlett, Christine DeLorenzo, Xuejing Lin, Laura Kunkel, Nehal P Vadhan, Greg Perlman, Michala Godstrey, Daniel Holzmacher, R Todd Ogden, Ramin V Parsey, Chuan Huan. Prediction of lithium treatment response in bipolar depression using 5-HTT and 5-HT European journal of nuclear medicine and molecular imaging. vol 47. issue 10. 2021-05-14. PMID:32055965. |
prediction of lithium treatment response in bipolar depression using 5-htt and 5-ht lithium, one of the few effective treatments for bipolar depression (bpd), has been hypothesized to work by enhancing serotonergic transmission. |
2021-05-14 |
2023-08-13 |
Not clear |
| Andreia Morais, Tzu-Ting Liu, Tao Qin, Homa Sadhegian, Ilknur Ay, Damla Yagmur, Rosangela Mendes da Silva, David Chung, Bruce Simon, Rubem Guedes, Shih-Pin Chen, Shuu-Jiun Wang, Jiin-Cherng Yen, Cenk Ayat. Vagus nerve stimulation inhibits cortical spreading depression exclusively through central mechanisms. Pain. vol 161. issue 7. 2021-05-14. PMID:32142015. |
supporting a role for both norepinephrine and serotonin, csd suppression by nvns was inhibited by more than 50% after abrogating norepinephrinergic or serotonergic neurotransmission alone using specific neurotoxins; abrogating both completely blocked the nvns effect. |
2021-05-14 |
2023-08-13 |
rat |
| E S Lansk. Novel harmala-ocudelic tuning (HOT) for ocular disorders. Medical hypotheses. vol 143. 2021-05-14. PMID:32498006. |
the eye contains serotonin, and possesses serotonergic receptors and modulators. |
2021-05-14 |
2023-08-13 |
Not clear |
| E S Lansk. Novel harmala-ocudelic tuning (HOT) for ocular disorders. Medical hypotheses. vol 143. 2021-05-14. PMID:32498006. |
the hypothesized mechanism for this extraordinary action is tuning of the serotonergic receptors in the eye in their binding affinity for serotonin, a putative neurochemical "ocudelic" homologue to the psychedelic phenomenon, likely potentiated, according to clinical experience with classical hallucinogens, by therapeutic music, positive psychological "set," and conducive environmental "setting." |
2021-05-14 |
2023-08-13 |
Not clear |
| Raphael R Perim, Mohamed El-Chami, Elisa J Gonzalez-Rothi, Gordon S Mitchel. Baseline Arterial CO Frontiers in physiology. vol 12. 2021-05-13. PMID:33716760. |
maih-induced pltf is initiated by activation of spinally-projecting raphe serotonergic neurons during hypoxia and subsequent serotonin release near phrenic motor neurons. |
2021-05-13 |
2023-08-13 |
Not clear |
| Anna Åstrand, Davide Guerrieri, Svante Vikingsson, Robert Kronstrand, Henrik Gree. In vitro characterization of new psychoactive substances at the μ-opioid, CB1, 5HT Forensic science international. vol 317. 2021-05-12. PMID:33160102. |
in this study 60 nps and metabolites belonging to opioids, cannabinoids and serotonergic hallucinogens classes were screened for in vitro activation of the μ-opioid, cb1, 5-ht |
2021-05-12 |
2023-08-13 |
Not clear |
| Michaela Herz, Klaus Breh. Serotonin stimulates Echinococcus multilocularis larval development. Parasites & vectors. vol 14. issue 1. 2021-05-11. PMID:33407815. |
although several studies have focused on the serotonergic nervous system in parasitic flatworms, little is known on the role of serotonin in flatworm development. |
2021-05-11 |
2023-08-13 |
Not clear |
| K Koleva, O Pavlov, R Nikolov, R Beh. Deep brain stimulation as a possible treatment of hyperthermia in patients with serotonin syndrome. Medical hypotheses. vol 139. 2021-05-10. PMID:32251940. |
ss is a potentially life-threatening clinical condition that occurs as a result of a drug-induced increase in the intrasynaptic serotonin (5-hydroxytryptamine, 5-ht) levels due to overdose of a single drug or due to interaction between two or more drugs with serotonergic mechanism of action. |
2021-05-10 |
2023-08-13 |
Not clear |
| Burak Yaman, Ramazan Ba. Pindolol potentiates the antidepressant effect of venlafaxine by inhibiting 5-HT1A receptor in DRN neurons of mice. The International journal of neuroscience. 2021-05-10. PMID:32677492. |
antidepressants increase the level of 5-ht in the somatodendritic region of the serotonergic dorsal raphe nucleus (drn) neurons in the first few days of their usage, which, in turn, inhibits the serotonergic neurons locally. |
2021-05-10 |
2023-08-13 |
mouse |
| Durairaj Ragu Varman, Lankupalle D Jayanthi, Sammanda Ramamoorth. Glycogen synthase kinase-3ß supports serotonin transporter function and trafficking in a phosphorylation-dependent manner. Journal of neurochemistry. vol 156. issue 4. 2021-05-04. PMID:32797733. |
serotonin (5-ht) transporter (sert) plays a crucial role in serotonergic transmission in the central nervous system, and any aberration causes serious mental illnesses. |
2021-05-04 |
2023-08-13 |
mouse |