| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Richard M Stewart, Janice W Y Wong, Simone Mahfouda, Hugo A E Morandini, Pradeep Rao, Kevin C Runions, Florian D Zep. Acute Tryptophan Depletion Moja-De: A Method to Study Central Nervous Serotonin Function in Children and Adolescents. Frontiers in psychiatry. vol 10. 2020-09-28. PMID:32210845. |
the role of central nervous 5-ht function underlying these processes can be examined through serotonergic challenge methodologies. |
2020-09-28 |
2023-08-13 |
Not clear |
| Fereshteh Farajdokht, Saeed Sadigh-Eteghad, Alireza Majdi, Fariba Pashazadeh, Seyyed Mehdi Vatandoust, Mojtaba Ziaee, Fatemeh Safari, Pouran Karimi, Javad Mahmoud. Serotonergic system modulation holds promise for L-DOPA-induced dyskinesias in hemiparkinsonian rats: A systematic review. EXCLI journal. vol 19. 2020-09-28. PMID:32327954. |
the results revealed ten different categories of serotonergic agents, including but not limited to 5-ht |
2020-09-28 |
2023-08-13 |
rat |
| Awanish Mishra, Rajesh Kumar Goe. Modulatory Effect of Serotonergic System in Pentylenetetrazole-Induced Seizures and Associated Memory Deficit: Role of 5-HT Journal of epilepsy research. vol 9. issue 2. 2020-09-28. PMID:32509547. |
modulatory effect of serotonergic system in pentylenetetrazole-induced seizures and associated memory deficit: role of 5-ht recent studies have recognised the memory deficit as one of the most common psychiatric issues in the patients with epilepsy, which severely affects the quality of life. |
2020-09-28 |
2023-08-13 |
Not clear |
| Meagan A Quinlan, Matthew J Robson, Ran Ye, Kristie L Rose, Kevin L Schey, Randy D Blakel. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32581705. |
the presynaptic, high-affinity 5-ht transporter (sert) tightly regulates 5-ht clearance after release from serotonergic neurons in the brain and enteric nervous systems, among other sites. |
2020-09-28 |
2023-08-13 |
human |
| Skirmantas Janušonis, Nils Detering, Ralf Metzler, Thomas Vojt. Serotonergic Axons as Fractional Brownian Motion Paths: Insights Into the Self-Organization of Regional Densities. Frontiers in computational neuroscience. vol 14. 2020-09-28. PMID:32670042. |
specifically, we use supercomputing simulations to model fibers as fbm-paths in two-dimensional brain-like domains and demonstrate that the resultant steady state distributions approximate the fiber distributions in physical brain sections immunostained for the serotonin transporter (a marker for serotonergic axons in the adult brain). |
2020-09-28 |
2023-08-13 |
Not clear |
| Georg A Petroianu, Dietrich E Lork. The Role of Serotonin in Singultus: A Review. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32765206. |
both afferent and efferent vagal activity and the central integration of the xth cranial nerve function are modulated, inter alia, via serotonergic mechanisms; beneficial (therapeutic) effects for hiccup are to be expected from serotonin (5-ht) receptor subtype ligands that enhance vagal activity. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jate Bernard, Abigail Greenhalgh, Oscar Istas, Nicole T Marguerite, Robin L Coope. The Effect of Bacterial Endotoxin LPS on Serotonergic Modulation of Glutamatergic Synaptic Transmission. Biology. vol 9. issue 8. 2020-09-28. PMID:32781679. |
since antidepressants related to the serotonergic system have been shown to have a positive outcome for septicemic conditions impacting the central nervous system, the actions of serotonin (5-ht) on neurons also exposed to lps were investigated. |
2020-09-28 |
2023-08-13 |
Not clear |
| Bruno Campos, Claudia Rivetti, Roma Tauler, Benjamin Piña, Carlos Barat. Tryptophan hydroxylase (TRH) loss of function mutations in Daphnia deregulated growth, energetic, serotoninergic and arachidonic acid metabolic signalling pathways. Scientific reports. vol 9. issue 1. 2020-09-24. PMID:30842467. |
bi-allelic mutants, lacking serotonin, presented the serotonergic synapse and arachidonic acid metabolic pathways down-regulated while the tryptophan to kynurenine was upregulated, thus indicating a cross-talk between the serotonergic and arachidonic acid metabolic pathways. |
2020-09-24 |
2023-08-13 |
Not clear |
| Chirag Upreti, Edward Konstantinov, Stefan R Kassabov, Craig H Bailey, Eric R Kande. Serotonin Induces Structural Plasticity of Both Extrinsic Modulating and Intrinsic Mediating Circuits In Vitro in Aplysia Californica. Cell reports. vol 28. issue 11. 2020-09-16. PMID:31509754. |
to test this idea, we added a bona fide serotonergic modulatory neuron, the metacerebral cell (mcc), to sensory-motor neuron co-cultures and examined the modulating presynaptic varicosities of mccs before and after repeated pulses of serotonin (5-ht) that induced long-term facilitation (ltf). |
2020-09-16 |
2023-08-13 |
aplysia |
| Chirag Upreti, Edward Konstantinov, Stefan R Kassabov, Craig H Bailey, Eric R Kande. Serotonin Induces Structural Plasticity of Both Extrinsic Modulating and Intrinsic Mediating Circuits In Vitro in Aplysia Californica. Cell reports. vol 28. issue 11. 2020-09-16. PMID:31509754. |
we observed robust growth of new serotonergic varicosities that were positive for serotonin and capable of synaptic recycling. |
2020-09-16 |
2023-08-13 |
aplysia |
| Zhuo-Ying Tao, Pei-Xing Wang, Si-Qi Wei, Richard J Traub, Jin-Feng Li, Dong-Yuan Ca. The Role of Descending Pain Modulation in Chronic Primary Pain: Potential Application of Drugs Targeting Serotonergic System. Neural plasticity. vol 2019. 2020-09-15. PMID:31933624. |
in this review, we summarize the possible underlying descending pain regulation mechanisms in cpp and the role of serotonin, thus providing evidence for potential application of analgesic medications based on the serotonergic system in cpp patients. |
2020-09-15 |
2023-08-13 |
Not clear |
| José Ángel García-Pedraza, Mónica García-Domingo, Miriam Gómez-Roso, Laura Ruiz-Remolina, Alicia Rodríguez-Barbero, María Luisa Martín, Asunción Morá. Hypertension exhibits 5-HT Hypertension research : official journal of the Japanese Society of Hypertension. vol 42. issue 5. 2020-09-14. PMID:30696976. |
we investigated the influence of in vivo 5-ht by characterizing the implicated serotonergic receptors on the mesenteric sympathetic outflow in rats with n-nitro-l-arginine methyl ester (l-name)-induced hypertension. |
2020-09-14 |
2023-08-13 |
rat |
| Margaret W Lieb, Magdalena Weidner, Mathew R Arnold, Kelsey M Loupy, Kadi T Nguyen, James E Hassell, K'Loni S Schnabel, Raphael Kern, Heidi E W Day, Klaus-Peter Lesch, Jonas Waider, Christopher A Lowr. Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice. Behavioural brain research. vol 373. 2020-09-14. PMID:31319134. |
serotonergic genes studied included tph2, the high-affinity, low-capacity, sodium-dependent serotonin transporter (slc6a4), the serotonin type 1a receptor (htr1a), and the corticosterone-sensitive, low-affinity, high-capacity sodium-independent serotonin transporter, organic cation transporter 3 (slc22a3). |
2020-09-14 |
2023-08-13 |
mouse |
| Wen-Jun Zou, Yun-Long Song, Min-Yi Wu, Xiang-Tian Chen, Qiang-Long You, Qian Yang, Zheng-Yi Luo, Lang Huang, Yin Kong, Jing Feng, Dong-Xiang Fang, Xiao-Wen Li, Jian-Ming Yang, Lin Mei, Tian-Ming Ga. A discrete serotonergic circuit regulates vulnerability to social stress. Nature communications. vol 11. issue 1. 2020-09-14. PMID:32839452. |
we identified a distinct, anatomically and functionally defined serotonergic subpopulation in the dr that projects to the vta (5-ht |
2020-09-14 |
2023-08-13 |
Not clear |
| J Gendron, C Colace-Sauty, N Beaume, H Cartonnet, J Guegan, D Ulveling, C Pardanaud-Glavieux, I Moszer, H Cheval, P Ravassar. Long non-coding RNA repertoire and open chromatin regions constitute midbrain dopaminergic neuron - specific molecular signatures. Scientific reports. vol 9. issue 1. 2020-09-11. PMID:30723217. |
most of them were not found in hindbrain serotonergic (5-ht) neurons, indicating a high degree of cell-specificity. |
2020-09-11 |
2023-08-13 |
mouse |
| Ting-Ren Chen, Hui-Chuan Huang, Jer-Hwa Hsu, Wen-Chen Ouyang, Kuan-Chia Li. Pharmacological and psychological interventions for generalized anxiety disorder in adults: A network meta-analysis. Journal of psychiatric research. vol 118. 2020-09-08. PMID:31494377. |
the results showed that all pharmacological treatments except for serotonin modulators and second-generation antipsychotics had greater effects than placebo: norepinephrine-dopamine reuptake inhibitors (standardized mean difference (smd) -1.84, 95% credible interval -3.05 to -0.62), noradrenergic and specific serotonergic antidepressants (-0.91, -1.62 to -0.20), melatonergic receptor agonists (-0.68, -1.15 to -0.21), selective serotonin reuptake inhibitors (ssris; -0.67, -0.90 to -0.43), azapirones (-0.58, -1.00 to -0.17), anticonvulsants (-0.56, -0.85 to -0.28), serotonin-norepinephrine reuptake inhibitors (snris; -0.54, -0.79 to -0.30), and benzodiazepines (bzds; -0.40, -0.65 to -0.15). |
2020-09-08 |
2023-08-13 |
human |
| Marcel van de Wouw, Roman M Stilling, Veronica L Peterson, Feargal J Ryan, Alan E Hoban, Fergus Shanahan, Gerard Clarke, Marcus J Claesson, Timothy G Dinan, John F Cryan, Harriët Schelleken. Host Microbiota Regulates Central Nervous System Serotonin Receptor 2C Editing in Rodents. ACS chemical neuroscience. vol 10. issue 9. 2020-08-31. PMID:31415146. |
one aspect of the serotonergic system that has been left unexplored in relation to the microbiota is the unique ability of the serotonin receptor 2c (5-ht |
2020-08-31 |
2023-08-13 |
Not clear |
| Melissa J Maguire, Cerian F Jackson, Anthony G Marson, Sarah J Nevit. Treatments for the prevention of Sudden Unexpected Death in Epilepsy (SUDEP). The Cochrane database of systematic reviews. vol 4. 2020-08-31. PMID:32239759. |
preventative strategies for sudep include reducing the occurrence of gtcs by timely referral for presurgical evaluation in people with lesional epilepsy and advice on lifestyle measures; detecting cardiorespiratory distress through clinical observation and seizure, respiratory, and heart rate monitoring devices; preventing airway obstruction through nocturnal supervision and safety pillows; reducing central hypoventilation through physical stimulation and enhancing serotonergic mechanisms of respiratory regulation using selective serotonin reuptake inhibitors (ssris); and reducing adenosine and endogenous opioid-induced brain and brainstem depression. |
2020-08-31 |
2023-08-13 |
Not clear |
| Clare E Howard, Chin-Lin Chen, Tanya Tabachnik, Rick Hormigo, Pavan Ramdya, Richard S Man. Serotonergic Modulation of Walking in Drosophila. Current biology : CB. vol 29. issue 24. 2020-08-24. PMID:31786064. |
these multifaceted roles of serotonin in locomotion are differentially mediated by a family of serotonergic receptors with distinct activities and expression patterns. |
2020-08-24 |
2023-08-13 |
drosophila_melanogaster |
| Angela Maria Casaril, Micaela Domingues, Darling de Andrade Lourenço, Paloma Taborda Birmann, Nathalia Padilha, Beatriz Vieira, Karine Begnini, Fabiana Kommling Seixas, Tiago Collares, Eder João Lenardão, Lucielli Savegnag. Depression- and anxiogenic-like behaviors induced by lipopolysaccharide in mice are reversed by a selenium-containing indolyl compound: Behavioral, neurochemical and computational insights involving the serotonergic system. Journal of psychiatric research. vol 115. 2020-08-20. PMID:31082651. |
considering these pharmacological properties and the structural similarities between tryptophan, serotonin and cmi, the aim of the present study was to investigate whether cmi ameliorates depression- and anxiogenic-like behavior induced by lipopolysaccharide (lps) in swiss male mice by modulating the serotonergic system and reducing neuroinflammation. |
2020-08-20 |
2023-08-13 |
mouse |