| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Sapun-Malcolm, J M Farah, G P Muelle. Evidence for serotonergic stimulation of pituitary beta-endorphin release: preferential release from the anterior lobe in vivo. Life sciences. vol 33. issue 1. 1983-08-11. PMID:6306375. |
together, these findings indicate that serotonergic drugs predominantly influence the release of beta-end-li resembling beta-lph and further suggest that serotonin neurons preferentially regulate the release of beta-end-li from al corticotrophs in vivo. |
1983-08-11 |
2023-08-12 |
rat |
| C Fornal, M Radulovack. Sleep suppressant action of fenfluramine in rats. I. Relation to postsynaptic serotonergic stimulation. The Journal of pharmacology and experimental therapeutics. vol 225. issue 3. 1983-08-11. PMID:6683311. |
the increase in serotonergic activity produced by fenfluramine may result from the drug-induced release of 5-ht with subsequent stimulation of postsynaptic 5-ht receptors. |
1983-08-11 |
2023-08-12 |
rat |
| M E Reith, H Sershen, D L Allen, A Lajth. A portion of [3H]cocaine binding in brain is associated with serotonergic neurons. Molecular pharmacology. vol 23. issue 3. 1983-08-11. PMID:6865907. |
only the serotonin neurotoxins decreased the binding of [3h]cocaine in the rat cerebral cortex, but to a lower extent than the binding of [3]imipramine, which is known to be associated with serotonergic terminals. |
1983-08-11 |
2023-08-12 |
mouse |
| E C Degli Uberti, G Trasforini, A R Margutti, C A Rotola, M Bianconi, P Pansin. Effect of ketanserin, an inhibitor of 5-HT2 receptors, on the aldosterone-stimulating action of metoclopramide. Hormone research. vol 17. issue 3. 1983-07-15. PMID:6343215. |
to estimate the possible involvement of a peripheral serotonergic pathway in the mechanism of the aldosterone-stimulating effect of metoclopramide (m) the plasma aldosterone (pa), renin activity (pra) and prolactin (prl) response to m was studied in 6 normal subjects before and after administration of ketanserin (k), a pure, specific, and selective blocking agent of 5-hydroxytryptamine type 2 (5-ht2) receptors. |
1983-07-15 |
2023-08-12 |
human |
| Y Takeuchi, Y San. Immunohistochemical demonstration of serotonin-containing nerve fibers in the inferior olivary complex of the rat, cat and monkey. Cell and tissue research. vol 231. issue 1. 1983-07-15. PMID:6850794. |
in the rat, the overall density of serotonin fibers was sparser than that in the other two species; the highest concentration of varicose serotonergic fibers was noted in the lateral portion of the dorsal accessory olive. |
1983-07-15 |
2023-08-12 |
rat |
| G Racagni, I Mocchetti, G Calderini, A Battistella, N Brunell. Temporal sequence of changes in central noradrenergic system of rat after prolonged antidepressant treatment: receptor desensitization and neurotransmitter interactions. Neuropharmacology. vol 22. issue 3 Spec No. 1983-07-08. PMID:6304559. |
since [3h]-imi and [3h]-dmi recognition sites have been shown to be located on serotonergic (5-ht) and noradrenergic neurones respectively, the interactions between ne and 5-ht neurones could represent possible mechanisms implicated in receptor desensitization. |
1983-07-08 |
2023-08-12 |
rat |
| G Racagni, I Mocchetti, G Calderini, A Battistella, N Brunell. Temporal sequence of changes in central noradrenergic system of rat after prolonged antidepressant treatment: receptor desensitization and neurotransmitter interactions. Neuropharmacology. vol 22. issue 3 Spec No. 1983-07-08. PMID:6304559. |
the experiments presented involving lesions of 5-ht neurones have clearly demonstrated that ne release in rat cerebral cortex is under a tonic serotonergic influence. |
1983-07-08 |
2023-08-12 |
rat |
| A H Neufeld, S E Ledgard, B K Yoz. Changes in responsiveness of the beta-adrenergic and serotonergic pathways of the rabbit corneal epithelium. Investigative ophthalmology & visual science. vol 24. issue 5. 1983-06-10. PMID:6132896. |
topical serotonin causes decreased responsiveness of the serotonergic pathway. |
1983-06-10 |
2023-08-12 |
rabbit |
| J Feigenbaum, J Yanai, H L Klawans, R Chatterto. The combined effect of quipazine and haloperidol on plasma prolactin release. The International journal of neuroscience. vol 18. issue 1-2. 1983-06-10. PMID:6840980. |
the possible dopaminergic properties of the central serotonergic agonist quipazine was examined using plasma prolactin release as a model to determine whether quipazine exerts an agonist effect on only serotonin receptors or on dopamine receptors as well. |
1983-06-10 |
2023-08-12 |
Not clear |
| H J Cooke, M Montakhab, P R Wade, J D Woo. Transmural fluxes of 5-hydroxytryptamine in guinea pig ileum. The American journal of physiology. vol 244. issue 4. 1983-05-27. PMID:6837747. |
the data are not consistent with the hypothesis of a "tissue barrier" that functions to prevent 5-ht from reaching serotonergic receptors on enteric ganglion cells or enteroendocrine cells. |
1983-05-27 |
2023-08-12 |
Not clear |
| H G Westenberg, H M van Praag, J T de Jong, J H Thijsse. Postsynaptic serotonergic activity in depressive patients: evaluation of the neuroendocrine strategy. Psychiatry research. vol 7. issue 3. 1983-04-15. PMID:6984515. |
the possible occurrence of hypersensitive postsynaptic serotonin (5-hydroxytryptamine; 5-ht) receptors in depressive patients was investigated using a neuroendocrine strategy: determination of neuroendocrine parameters after activation of the serotonergic system. |
1983-04-15 |
2023-08-12 |
human |
| H G Westenberg, H M van Praag, J T de Jong, J H Thijsse. Postsynaptic serotonergic activity in depressive patients: evaluation of the neuroendocrine strategy. Psychiatry research. vol 7. issue 3. 1983-04-15. PMID:6984515. |
since administration of 5-ht precursors caused no significant change in the hormone concentrations, evaluation of neuroendocrine function after stimulation with 5-ht precursors does not appear to provide a reliable index of human postsynaptic serotonergic activity. |
1983-04-15 |
2023-08-12 |
human |
| T S Jensen, D F Smit. Role of 5-HT and NA in spinal dopaminergic analgesia. European journal of pharmacology. vol 86. issue 1. 1983-04-07. PMID:6297926. |
however, pretreatment of intact rats with the serotonergic (5-ht) receptor antagonist methysergide, the noradrenergic (na) receptor antagonist phentolamine or the two antagonists together led to a dose-dependent analgesia following apomorphine. |
1983-04-07 |
2023-08-12 |
rat |
| Y Takeuchi, H Kimura, T Matsuura, T Yonezawa, Y San. Distribution of serotonergic neurons in the central nervous system: a peroxidase-antiperoxidase study with anti-serotonin antibodies. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 31. issue 1A Suppl. 1983-04-07. PMID:6338102. |
serotonergic neuronal somata are organized according to certain basic patterns, but there are interspecific differences with regard to the distribution of 5-ht fibers. |
1983-04-07 |
2023-08-12 |
cattle |
| B S Beltz, E A Kravit. Mapping of serotonin-like immunoreactivity in the lobster nervous system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 3. issue 3. 1983-04-07. PMID:6338162. |
to begin the examination of the role of serotonin in lobsters at a cellular level, we have used immunohistochemical methods to search for presumptive serotonergic neurons, their central and peripheral projections, and their terminal fields of arborization. |
1983-04-07 |
2023-08-12 |
lobster |
| A A Larso. Nociception is enhanced by the intrathecal injection of 5-methoxy-N,N-dimethyltryptamine in the rat. Neuroscience letters. vol 33. issue 3. 1983-04-07. PMID:7162694. |
the ability of 5-meodmt to mimic the facilitatory (hyperalgesic) effect on nociception of similar doses of tryptamine, in contrast to the antinociceptive (analgesic) effect of serotonin, suggests an interaction of 5-meodmt with tryptaminergic rather than serotonergic receptors in the spinal cord. |
1983-04-07 |
2023-08-12 |
rat |
| P I Korner, G A Hea. Cardiovascular functions of central noradrenergic and serotonergic neurons in conscious rabbits. Their contributions to the central actions of clonidine. Chest. vol 83. issue 2 Suppl. 1983-03-24. PMID:6401613. |
synaptic release of transmitter from central noradrenergic (na) and serotonergic (5ht) neurons was studied in intact and pontine decerebrate unanesthetized rabbits, following intracisternal injections of the selective neurotoxic drugs 6-hydroxydopamine (6-ohda) and 5,6-dihydroxytryptamine (5,6-dht). |
1983-03-24 |
2023-08-12 |
Not clear |
| P M Vanhoutte, J M Van Nueten, J Symoens, P A Jansse. Antihypertensive properties of ketanserin (R 41 468). Federation proceedings. vol 42. issue 2. 1983-03-17. PMID:6295821. |
the serotonergic receptor antagonist 3-(2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl)-2,4-[1h, 3h] quinazolinedione (ketanserin) causes dose-dependent inhibition of the effects of 5-hydroxytryptamine (5-ht) on 5-ht2-serotonergic receptors. |
1983-03-17 |
2023-08-12 |
Not clear |
| J M Van Nuete. 5-hydroxytryptamine and precapillary vessels. Federation proceedings. vol 42. issue 2. 1983-03-17. PMID:6295823. |
the vasodilator component of the response to 5-ht can be unmasked in the presence of serotonergic blockade, provided the antagonist used has no partial agonistic properties. |
1983-03-17 |
2023-08-12 |
Not clear |
| G Luscombe, P Jenner, C D Marsde. Tryptamine-induced myoclonus in guinea-pigs pretreated with a monoamine oxidase inhibitor indicates pre- and post-synaptic actions of tryptamine upon central indoleamine systems. Neuropharmacology. vol 21. issue 12. 1983-03-11. PMID:6130489. |
manipulation of presynaptic function of 5-hydroxytryptamine (5ht) by tryptophan hydroxylase inhibition with p-chlorophenylalanine to produce depletion of cerebral 5ht, or by an l-tryptophan load to elevate 5ht in brain, suggested that the functional integrity of serotonergic neurones is required for the expression of myoclonus induced by tryptamine plus pargyline. |
1983-03-11 |
2023-08-12 |
Not clear |