| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R N Hughe. Cholinergic and monoaminergic substrates of startle habituation. Life sciences. vol 34. issue 22. 1984-07-13. PMID:6727553. |
likewise, serotonergic drug effects do not favor the more recent view that startle habituation depends on brain serotonin, nor is there sufficient evidence for an essential role of either dopamine or noradrenaline . |
1984-07-13 |
2023-08-12 |
rat |
| b' J Culman, A Kiss, R Kvetnansk\\xc3\\xb. Serotonin and tryptophan hydroxylase in isolated hypothalamic and brain stem nuclei of rats exposed to acute and repeated immobilization stress. Experimental and clinical endocrinology. vol 83. issue 1. 1984-07-09. PMID:6539213.' |
the increased tryptophan hydroxylase activity observed without any changes in serotonin concentration in the locus coeruleus after the 7th immobilization may suggest an increased synthesis and release rate of serotonin in serotonergic nerve terminals in this area. |
1984-07-09 |
2023-08-12 |
rat |
| L E Lindblad, J T Shepherd, P M Vanhoutt. Cooling augments platelet-induced contraction of peripheral arteries of the dog. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 176. issue 2. 1984-06-18. PMID:6718355. |
norepinephrine, 5-hydroxytryptamine, and autologous aggregating platelets all caused contractions that were augmented by cooling the bath content from 37 to 24 degrees c. these contractions were inhibited, in a concentration-dependent manner, by the serotonergic antagonist ketanserin. |
1984-06-18 |
2023-08-12 |
dog |
| R Gervais, S Araneda, J F Pujo. Effect of local 5,6-dihydroxytryptamine on the rat olfactory bulb responsiveness during wakefulness and sleep. Electroencephalography and clinical neurophysiology. vol 57. issue 5. 1984-06-05. PMID:6201341. |
this study investigated a possible participation of the centrifugal serotonergic (5-ht) innervation of the olfactory bulb (ob) in the control of the multiunit mitral cell responsiveness in behaving rats. |
1984-06-05 |
2023-08-12 |
rat |
| M Smiałowska, A Ba. The effect of morphine on 5-hydroxytryptamine and catecholamine neurons in the rat brain. Histofluorescence studies. Journal of neural transmission. vol 59. issue 1. 1984-06-01. PMID:6716097. |
on serotonergic (5-ht) and catecholaminergic (ca) neurons in several areas of the rat brain was studied using the falck-hillarp histofluorescence method. |
1984-06-01 |
2023-08-12 |
rat |
| Y Nagatsuk. [The regulation of pituitary gonadotropin release of the frontal lobe neocortex. (II). In relation to serotonergic neurons]. Nihon Naibunpi Gakkai zasshi. vol 59. issue 12. 1984-05-30. PMID:6232156. |
these results suggest that serotonergic neurons ascending from the dorsal raphe nucleus are involved in the inhibition of lh secretion and ovulation caused by electrochemical stimulation of the anterior frontal lobe neocortex and that the secretion of serotonin is necessary for the inhibition of lh secretion. |
1984-05-30 |
2023-08-12 |
rat |
| W A Turski, S J Czuczwar, L Turski, M Sieklucka-Dziuba, Z Kleinro. Studies on the mechanism of wet dog shakes produced by carbachol in rats. Pharmacology. vol 28. issue 2. 1984-05-18. PMID:6200891. |
in an attempt to elucidate the mechanism of wet dog shakes (wds) produced by carbachol administered into the rat lateral brain ventricle, the effects of blockade of muscarinic and nicotinic receptors on shaking response and the effects of carbachol on central catecholaminergic, serotonergic (5-ht) and gabaergic functions were studied in rats. |
1984-05-18 |
2023-08-12 |
rat |
| J F McElroy, J M Miller, J S Meye. Fenfluramine, p-chloroamphetamine and p-fluoroamphetamine stimulation of pituitary-adrenocortical activity in rat: evidence for differences in site and mechanism of action. The Journal of pharmacology and experimental therapeutics. vol 228. issue 3. 1984-05-02. PMID:6323674. |
animals were pretreated with various serotonergic drugs before fen, pca or pfa in order to ascertain the role of 5-ht in mediating the pituitary-adrenocortical response to each compound. |
1984-05-02 |
2023-08-12 |
rat |
| J F McElroy, J M Miller, J S Meye. Fenfluramine, p-chloroamphetamine and p-fluoroamphetamine stimulation of pituitary-adrenocortical activity in rat: evidence for differences in site and mechanism of action. The Journal of pharmacology and experimental therapeutics. vol 228. issue 3. 1984-05-02. PMID:6323674. |
as expected, pca elevates corticosterone levels through a central serotonergic mechanism that requires the continued synthesis and storage of 5-ht. |
1984-05-02 |
2023-08-12 |
rat |
| L J Siever, D L Murphy, S Slater, E de la Vega, S Lippe. Plasma prolactin changes following fenfluramine in depressed patients compared to controls: an evaluation of central serotonergic responsivity in depression. Life sciences. vol 34. issue 11. 1984-04-26. PMID:6700367. |
in an attempt to evaluate the responsiveness of the serotonergic neurotransmitter system in depression, fenfluramine, a serotonin releasing agent, was administered to 18 depressed patients and 10 controls, and placebo was administered to 16 of the depressed patients in a double-blind paradigm. |
1984-04-26 |
2023-08-12 |
Not clear |
| M K Stachowiak, J P Bruno, A M Snyder, E M Stricker, M J Zigmon. Apparent sprouting of striatal serotonergic terminals after dopamine-depleting brain lesions in neonatal rats. Brain research. vol 291. issue 1. 1984-04-25. PMID:6199080. |
this effect was associated with an increase in in vitro high affinity 5-ht uptake, suggesting that proliferation of new serotonergic terminals had occurred within the striatum. |
1984-04-25 |
2023-08-12 |
rat |
| R M Clemmons, K M Meyer. Acquisition and aggregation of canine blood platelets: basic mechanisms of function and differences because of breed origin. American journal of veterinary research. vol 45. issue 1. 1984-04-24. PMID:6422804. |
irreversible aggregation to serotonin was associated with release of 3h-serotonin and thromboxane b2 formation, indicating that a couple between the serotonergic receptor and arachidonic acid metabolism may exist. |
1984-04-24 |
2023-08-12 |
Not clear |
| D W Gallager, J M Lakoski, S F Gonsalves, S L Rauc. Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity. Nature. vol 308. issue 5954. 1984-04-12. PMID:6322004. |
we present here electrophysiological evidence for decreased postsynaptic sensitivity to gaba following chronic benzodiazepine administration as measured by the direct iontophoretic application of gaba and serotonin onto serotonergic cells in the midbrain dorsal raphe nucleus (drn), known to receive gabaergic input. |
1984-04-12 |
2023-08-12 |
rat |
| M Bineau-Thurotte, F Godefroy, J Weil-Fugazza, J M Besso. The effect of morphine on the potassium evoked release of tritiated 5-hydroxytryptamine from spinal cord slices in the rat. Brain research. vol 291. issue 2. 1984-03-27. PMID:6697192. |
these results demonstrating a specific and dose-dependent increase in the potassium evoked release of [3h]5-ht from spinal dorsal cord slices after systemic administration of morphine, emphasize the role of serotonergic systems in such analgesia. |
1984-03-27 |
2023-08-12 |
rat |
| T Matsuura, Y San. distribution of monoamine-containing nerve fibers in the pineal organ of untreated and sympathectomized dogs. Fluorescence- and immunohistochemical studies. Cell and tissue research. vol 234. issue 3. 1984-03-23. PMID:6362886. |
these findings suggest that 1) the sympathetic noradrenergic fibers in the pineal organ of the dog take up serotonin which is released from the pinealocytes, and 2) this organ receives a dual monoamine innervation via peripheral noradrenergic and central serotonergic nerve fibers. |
1984-03-23 |
2023-08-12 |
dog |
| R M Bowker, K N Westlund, M C Sullivan, J F Wilber, J D Coulte. Descending serotonergic, peptidergic and cholinergic pathways from the raphe nuclei: a multiple transmitter complex. Brain research. vol 288. issue 1-2. 1984-03-14. PMID:6198030. |
the similar distributions of the descending serotonergic and peptidergic neurons in the raphe nuclei as well as quantitative data on their relative numbers suggest that a large fraction of raphe-spinal neurons contain serotonin co-existing with one or more peptides in the same cell. |
1984-03-14 |
2023-08-12 |
Not clear |
| D J Minnema, J A Rosecran. Amphetamine and LSD as discriminative stimuli: alterations following neonatal monoamine reductions. Pharmacology, biochemistry, and behavior. vol 20. issue 1. 1984-03-14. PMID:6420809. |
these data suggest that: (1) lsd and d-amphetamine discrimination stimuli are not mediated and/or influenced via the compromised aspects of the 5ht systems (other central mechanisms may have compromised for these 5ht deficits); (2) the lsd ds is mediated or influenced both by serotonergic and dopaminergic mechanisms; and (3) the d-amphetamine ds is mediated by certain aspects of the dopaminergic system with little evidence for the involvement of 5ht systems. |
1984-03-14 |
2023-08-12 |
rat |
| C P Vandermaelen, G K Aghajania. Electrophysiological and pharmacological characterization of serotonergic dorsal raphe neurons recorded extracellularly and intracellularly in rat brain slices. Brain research. vol 289. issue 1-2. 1984-03-12. PMID:6140982. |
these presumed serotonergic dr neurons were inhibited by lsd and serotonin. |
1984-03-12 |
2023-08-12 |
rat |
| P D Hrdin. Antidepressant binding: implications for the mode of action and the biology of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 7. issue 4-6. 1984-03-08. PMID:6320297. |
in the hippocampus of rats with a lesion of serotonergic nerve terminals produced by neonatal administration of 5,7-dht, the depletion of serotonin was paralleled by a decrease in (3h)imipramine recognition sites. |
1984-03-08 |
2023-08-12 |
rat |
| C de Montign. Electroconvulsive shock treatments enhance responsiveness of forebrain neurons to serotonin. The Journal of pharmacology and experimental therapeutics. vol 228. issue 1. 1984-02-29. PMID:6319668. |
inasmuch as long-term tricyclic antidepressant drug administration has been shown to produce a similar sensitization to serotonin, the present results suggest that enhancement of serotonergic neurotransmission might mediate the therapeutic effect of both types of treatment in major depression. |
1984-02-29 |
2023-08-12 |
rat |