| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Nagai, S Narumi, Y Saji, Y Nagaw. [A TRH analog (DN-1417). Anti-reserpine action in electroconvulsive threshold and involvement of serotonergic (5-HT) mechanism in mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 85. issue 4. 1985-08-21. PMID:3924796. |
anti-reserpine action in electroconvulsive threshold and involvement of serotonergic (5-ht) mechanism in mice]. |
1985-08-21 |
2023-08-11 |
mouse |
| L S Brady, J E Barret. Effects of serotonin receptor antagonists on punished responding maintained by stimulus-shock termination or food presentation in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 234. issue 1. 1985-08-20. PMID:4009495. |
these findings confirm the involvement of serotonergic pathways in punishment-suppressed operant behavior and suggest that different populations of 5-ht receptors modulate punished behavior maintained by different types of consequent events (i.e., stimulus-shock termination or food). |
1985-08-20 |
2023-08-11 |
monkey |
| M Wielos. Increased sensitivity to serotonergic agonists after repeated electroconvulsive shock in rats. Pharmacology, biochemistry, and behavior. vol 22. issue 5. 1985-08-09. PMID:2989938. |
the effect of single and repeated electroconvulsive shock (ecs) (once daily for 7 days) on head twitches produced by 5-ht agonists (licl, 5-hydroxytryptophan; 5-htp and 5-methoxytryptamine; 5-mt) was investigated 1 hr, 24 hr, 5 days and 10 days after the last ecs, while locomotor activity induced by serotonergic agonists (fenfluramine, 3-chlorophenylpiperazine; m-cpp) and antagonists (metergoline, cyproheptadine) was only investigated after 24 hr. |
1985-08-09 |
2023-08-11 |
rat |
| R King, K F Faull, S M Stahl, I N Mefford, S Thiemann, J D Barchas, P A Berge. Serotonin and schizophrenia: correlations between serotonergic activity and schizophrenic motor behavior. Psychiatry research. vol 14. issue 3. 1985-07-23. PMID:2408290. |
serotonin and schizophrenia: correlations between serotonergic activity and schizophrenic motor behavior. |
1985-07-23 |
2023-08-11 |
Not clear |
| J M Lakoski, G K Aghajania. Effects of ketanserin on neuronal responses to serotonin in the prefrontal cortex, lateral geniculate and dorsal raphe nucleus. Neuropharmacology. vol 24. issue 4. 1985-07-09. PMID:3158835. |
in the dorsal raphe nucleus of animals anesthetized with chloral hydrate, ketanserin neither attenuated nor potentiated the inhibition of serotonergic neurons by 5-ht. |
1985-07-09 |
2023-08-11 |
rat |
| C Lau, A Pylypiw, L L Ros. Development of serotonergic and adrenergic receptors in the rat spinal cord: effects of neonatal chemical lesions and hyperthyroidism. Brain research. vol 351. issue 1. 1985-06-25. PMID:2986790. |
the sympathetic preganglionic neurons in the spinal cord receive dense serotonergic (5-ht) and catecholaminergic (ca) afferent inputs from the descending supraspinal pathways. |
1985-06-25 |
2023-08-11 |
human |
| C Lau, A Pylypiw, L L Ros. Development of serotonergic and adrenergic receptors in the rat spinal cord: effects of neonatal chemical lesions and hyperthyroidism. Brain research. vol 351. issue 1. 1985-06-25. PMID:2986790. |
to determine whether the 5-ht and ca receptors in the developing spinal cord are also subject to such transsynaptic regulation, we examined the ontogeny of serotonergic receptors and alpha- and beta-adrenergic receptors in thoracolumbar spinal cord of rats given neurotoxins which destroy serotonergic (5,7-dihydroxytryptamine (5,7-dht)) or noradrenergic (6-hydroxydopamine (6-ohda)) nerve terminals. |
1985-06-25 |
2023-08-11 |
human |
| S F Sawyer, J M Tepper, S J Young, P M Grove. Antidromic activation of dorsal raphe neurons from neostriatum: physiological characterization and effects of terminal autoreceptor activation. Brain research. vol 332. issue 1. 1985-06-25. PMID:3873268. |
in conjunction with these antidromic activation studies, the neurophysiological consequences of serotonergic terminal autoreceptor activation were examined by measuring changes in the excitability of serotonergic terminal fields in the neostriatum following administration of the serotonin autoreceptor agonist, 5-methoxy-n,n-dimethyltryptamine (5-meodmt). |
1985-06-25 |
2023-08-11 |
rat |
| H K Kimelberg, D M Kat. High-affinity uptake of serotonin into immunocytochemically identified astrocytes. Science (New York, N.Y.). vol 228. issue 4701. 1985-06-24. PMID:3890180. |
the results indicate that mammalian astrocytes can take up serotonin by a sodium-dependent, high-affinity system previously thought to be the exclusive property of serotonergic nerve endings. |
1985-06-24 |
2023-08-11 |
rat |
| F C Zhou, E C Azmiti. The effect of adrenalectomy and corticosterone on homotypic collateral sprouting of serotonergic fibers in hippocampus. Neuroscience letters. vol 54. issue 2-3. 1985-06-20. PMID:3991054. |
lesioning of serotonergic (5-ht) fibers using 5,7-dihydroxytryptamine (5,7-dht) in one of the two median raphe-hippocampal pathways induced homotypic sprouting from the other. |
1985-06-20 |
2023-08-11 |
rat |
| G Boschi, N Launa. Differential effects of neuroleptic and serotonergic drugs on amphetamine-induced hypothermia in mice. Neuropharmacology. vol 24. issue 2. 1985-06-19. PMID:2859540. |
pretreatment with the serotonergic (5-ht) receptor blocker cyproheptadine also potentiated the hypothermia. |
1985-06-19 |
2023-08-11 |
mouse |
| K A Stauderman, D J Jone. Characterization of sodium-dependent, high-affinity serotonin uptake in rat spinal cord synaptosomes. Brain research. vol 330. issue 1. 1985-06-18. PMID:3872698. |
it is concluded that sodium-dependent [3h]serotonin accumulation reflects uptake into spinal serotonergic nerve terminals while sodium-independent accumulation probably reflects a temperature-sensitive binding to membrane fragments. |
1985-06-18 |
2023-08-11 |
rat |
| O Puciłowski, A Płaźnik, W Kostowsk. Aggressive behavior inhibition by serotonin and quipazine injected into the amygdala in the rat. Behavioral and neural biology. vol 43. issue 1. 1985-06-18. PMID:4039562. |
the effects on aggressive behavior, open-field activity, and pain threshold of bilateral microinjections of serotonin (20 micrograms) and quipazine (20 micrograms), the direct serotonergic receptor agonist, into the cortico-medial amygdala were investigated in wistar rats. |
1985-06-18 |
2023-08-11 |
rat |
| R F Payette, M D Gershon, E A Nune. Serotonergic elements of the mammalian pituitary. Endocrinology. vol 116. issue 5. 1985-05-30. PMID:3987625. |
the neural elements reactive with antisera to 5-ht or which labeled with [3h]5-ht differed in their distribution from neurites that labeled with [3h]dopamine or [3h]norepinephrine; moreover, lesioning of catecholaminergic neurites with 6-hydroxydopamine had no effect on the serotonergic structures. |
1985-05-30 |
2023-08-11 |
mouse |
| R Lalonde, V Vikis-Freiberg. Manipulations of 5-HT activity and memory in the rat. Pharmacology, biochemistry, and behavior. vol 22. issue 3. 1985-05-29. PMID:3873076. |
a non-specific inhibitor of 5-ht reuptake, imipramine, did not produce this amnesic effect, nor did the combination of fenfluramine with the maoi tranylcypromine, although it produced, as expected, the "serotonergic syndrome." |
1985-05-29 |
2023-08-11 |
rat |
| G Clementi, M Amico-Roxas, E Rapisarda, A Caruso, A Prato, S Trombadore, G Priolo, U Scapagnin. The analgesic activity of calcitonin and the central serotonergic system. European journal of pharmacology. vol 108. issue 1. 1985-05-15. PMID:3979435. |
the results obtained confirm that the analgesic activity of sct may involve central serotonergic pathway(s), and that the midbrain raphe nuclei 5-ht content is an important focus for this activity. |
1985-05-15 |
2023-08-11 |
rat |
| E Tempesta, L Janiri, C Pirrongell. Stereospecific effects of acetylcarnitine on the spontaneous activity of brainstem neurones and their responses to acetylcholine and serotonin. Neuropharmacology. vol 24. issue 1. 1985-05-10. PMID:2858832. |
l-acetylcarnitine increased both excitatory and inhibitory responses to 5-ht and its effect on the increase in firing rate induced by serotonergic drugs was reduced by dihydro-beta-erythroidine, but not by atropine. |
1985-05-10 |
2023-08-11 |
rat |
| S E Robinson, M J Austin, D M Gibben. The role of serotonergic neurons in dorsal raphe, median raphe and anterior hypothalamic pressor mechanisms. Neuropharmacology. vol 24. issue 1. 1985-05-10. PMID:3982602. |
the role of serotonergic neurons in the dorsal raphe and median raphe in the pressor response to electrical stimulation of these areas, and the contribution of these neurons to the pressor response to serotonin (5-ht) in the anterior hypothalamus-preoptic area (ah/po) have been studied by the use of local injections of 5,7-dihydroxytryptamine (5,7-dht), a neurotoxin selective for 5-hydroxytryptamine (5-ht). |
1985-05-10 |
2023-08-11 |
rat |
| F De Clerck, J M van Nueten, R S Renema. Platelet-vessel wall interactions: implication of 5-hydroxytryptamine. A review. Agents and actions. vol 15. issue 5-6. 1985-05-08. PMID:6397984. |
by interacting with 5-ht2 serotonergic receptors, 5-ht, directly or through amplification, activates platelets, endothelial and vascular smooth muscle cells producing platelet aggregation, vascular permeability increase and large vessel constriction. |
1985-05-08 |
2023-08-12 |
Not clear |
| E T Mellerup, P Plenge, M Nielse. Size determination of binding polymers for [3H]imipramine and [3H]paroxetine in human platelet membranes. European journal of pharmacology. vol 106. issue 2. 1985-04-26. PMID:6099278. |
imipramine and paroxetine both inhibit the transport of serotonin in serotonergic neurons and in platelets; furthermore specific high affinity binding sites for [3h]imipramine and [3h]paroxetine are located in these two cell types, probably on the serotonin transport mechanism. |
1985-04-26 |
2023-08-12 |
human |