| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Płaźnik, W Kostowski, W Danys. The involvement of brain serotonin in the clonidine-induced hypothermia in rats. Polish journal of pharmacology and pharmacy. vol 35. issue 4. 1984-02-29. PMID:6320143. |
the effects of manipulation with brain serotonergic (5ht) activity on clonidine-induced hypothermia in rats were investigated. |
1984-02-29 |
2023-08-12 |
rat |
| N A Sharif, D R Burt, A C Towle, R A Mueller, G R Brees. Codepletion of serotonin and TRH induces apparent supersensitivity of spinal TRH receptors. European journal of pharmacology. vol 95. issue 3-4. 1984-02-15. PMID:6317416. |
lesions of these serotonergic projections by intracisternal injection of 5,7-dihydroxytryptamine (50 micrograms) in rat pups resulted in 93% and 65% decreases in 5-ht and trh content of adult rat spinal cords, respectively. |
1984-02-15 |
2023-08-12 |
rat |
| S Närväne. Role of 5-hydroxytryptamine (serotonin) in oral glucose intolerance. Scandinavian journal of clinical and laboratory investigation. Supplementum. vol 167. 1984-02-14. PMID:6581528. |
thrombocytes have a mechanism for 5-ht uptake analogous to the reuptake mechanism for 5-ht in the serotonergic nerve terminals. |
1984-02-14 |
2023-08-12 |
human |
| S B Koevary, R C McEvoy, E C Azmiti. Evidence for the presence of serotonergic perikarya in the fetal rat pancreas as demonstrated by the high affinity uptake of [3H] 5-HT. Brain research. vol 280. issue 2. 1984-02-14. PMID:6652497. |
evidence for the presence of serotonergic perikarya in the fetal rat pancreas as demonstrated by the high affinity uptake of [3h] 5-ht. |
1984-02-14 |
2023-08-12 |
rat |
| T Nishikawa, M Tanaka, A Tsuda, Y Kohno, N Nagasak. Serotonergic-catecholaminergic interactions and foot shock-induced jumping behavior in rats. European journal of pharmacology. vol 94. issue 1-2. 1984-02-14. PMID:6653659. |
the role of serotonergic neurons in foot shock-induced jumping behavior was evaluated by studying the effects of serotonin agonists and depletors under conditions of increasing activity of catecholaminergic neurons by combining different shock intensities with methamphetamine or clonidine pretreatment. |
1984-02-14 |
2023-08-12 |
rat |
| E H Lee, M A Geye. Similarities of the effects of apomorphine and 3-PPP on serotonin neurons. European journal of pharmacology. vol 94. issue 3-4. 1984-02-14. PMID:6653663. |
the differential effects of 3-ppp on the mesostriatal and mesolimbic serotonergic systems further confirm that the dorsal and median raphe nuclei constitute two anatomically and functionally distinct cell groups and the similarities of the effects of apo and 3-ppp indicate that dopamine autoreceptors may mediate the observed effects of apo on 5-ht neurons. |
1984-02-14 |
2023-08-12 |
Not clear |
| A Barbe. Properties of the serotonergic cerebral ganglion neurons of the gastropod mollusc, Philine aperta. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 76. issue 1. 1984-01-27. PMID:6139241. |
because they appear to contain serotonin, and since they probably also use serotonin as a neurotransmitter, these neurons were named the serotonergic cerebral neurons (scns). |
1984-01-27 |
2023-08-12 |
Not clear |
| G A Head, P I Korner, S L Lewis, E Badoe. Contribution of noradrenergic and serotonergic neurons to the circulatory effects of centrally acting clonidine and alpha-methyldopa in rabbits. Journal of cardiovascular pharmacology. vol 5. issue 6. 1984-01-27. PMID:6196566. |
neurochemical findings suggest that 6-ohda affected noradrenergic (na), dopaminergic (da), but not serotonergic (5ht) neurons, and that 5,6-dht affected 5ht but not na and da neurons. |
1984-01-27 |
2023-08-12 |
Not clear |
| M W Wessendorf, E G Anderso. Single unit studies of identified bulbospinal serotonergic units. Brain research. vol 279. issue 1-2. 1984-01-27. PMID:6315185. |
despite these differences, both groups of serotonergic units were found to be consistently inhibited by ach, ne and 5-ht. |
1984-01-27 |
2023-08-12 |
Not clear |
| O B Fasmer, O G Berge, B Walther, K Hol. Changes in nociception after intrathecal administration of 5,6-dihydroxytryptamine in mice. Neuropharmacology. vol 22. issue 10. 1984-01-27. PMID:6689057. |
intrathecal administration of 5,6-dihydroxytryptamine (5,6-dht) (5 micrograms) to mice selectively lesioned descending serotonergic pathways, reducing spinal levels of 5-hydroxytryptamine (5-ht) by 80%, without significantly changing the levels of noradrenaline. |
1984-01-27 |
2023-08-12 |
mouse |
| H Y Meltzer, B Uberkoman-Wiita, A Robertson, B J Tricou, M Low. Enhanced serum cortisol response to 5-hydroxytryptophan in depression and mania. Life sciences. vol 33. issue 25. 1984-01-26. PMID:6645813. |
in view of evidence for decreased brain serotonergic activity in depression and perhaps mania, the results suggest at least some serotonin receptors may be supersensitive in some patients with affective disorders. |
1984-01-26 |
2023-08-12 |
Not clear |
| J B Long, W W Youngblood, J S Kize. Effects of castration and adrenalectomy on in vitro rates of tryptophan hydroxylation and levels of serotonin in microdissected brain nuclei of adult male rats. Brain research. vol 277. issue 2. 1984-01-07. PMID:6605782. |
furthermore, the dissociation between serum and brain tryptophan concentrations and changes in rates of 5-htp synthesis argue against tryptophan availability as being a primary determinant of 5-ht biosynthesis and for a direct endocrine central nervous system interaction with serotonergic neurons. |
1984-01-07 |
2023-08-12 |
rat |
| S Ichida, H Tokunaga, Y Oda, N Fujita, A Hirata, T Hat. Increase of serotonin receptors in rat uterus induced by estradiol. The Journal of biological chemistry. vol 258. issue 22. 1984-01-07. PMID:6643435. |
cinanserin, mianserin, metergoline (which are serotonergic antagonists), and serotonin (5-ht) inhibited the [3h]spiroperidol binding with apparent ki values of 21.2, 14.1, 14.1, and 176.5 microm, respectively. |
1984-01-07 |
2023-08-12 |
rat |
| E G Ezrailson, M L Entman, A J Garbe. Adrenergic and serotonergic regulation of skeletal muscle metabolism in rat. I. The effects of adrenergic and serotonergic antagonists on the regulation of muscle amino acid release, glycogenolysis, and cyclic nucleotide levels. The Journal of biological chemistry. vol 258. issue 20. 1983-12-17. PMID:6313662. |
in contrast, serotonergic antagonists such as methysergide (10(-8)-10(-6) m) and cyproheptadine (10(-8)-10(-6) m) blocked the inhibition of alanine and glutamine release, the stimulations of muscle camp levels and phosphorylase a formation, and the decreased muscle glycogen content effected by serotonin but not by epinephrine. |
1983-12-17 |
2023-08-12 |
rat |
| M L Cohen, R W Fuller, K D Kur. LY53857, a selective and potent serotonergic (5-HT2) receptor antagonist, does not lower blood pressure in the spontaneously hypertensive rat. The Journal of pharmacology and experimental therapeutics. vol 227. issue 2. 1983-12-17. PMID:6313898. |
ly53857 was a potent antagonist of vascular contraction to serotonin, which is mediated by serotonergic (5-ht2) receptors, with a dissociation constant in vitro of 5.4 x 10(-11) m. unlike several other serotonin antagonists, ly53857 showed minimal affinity for vascular alpha adrenergic receptors (dissociation constant of 1.4 x 10(-5) m). |
1983-12-17 |
2023-08-12 |
rat |
| R D Hall, J P Leahy, W M Robertso. Hyposensitivity to serotonergic stimulation in protein malnourished rats. Physiology & behavior. vol 31. issue 2. 1983-12-17. PMID:6579573. |
in the present study we asked whether the elevated 5-ht levels of associated with any changes in sensitivity to serotonergic stimulation. |
1983-12-17 |
2023-08-12 |
rat |
| C H Bailey, R D Hawkins, M C Che. Uptake of [3H]serotonin in the abdominal ganglion of Aplysia californica. Further studies on the morphological and biochemical basis of presynaptic facilitation. Brain research. vol 272. issue 1. 1983-11-23. PMID:6193837. |
in the present study we have used the specific uptake [3h]serotonin ([3h]5-ht) and electron-microscopic autoradiography in combination with horseradish peroxidase-labeling of identified neurons to characterize the fine structure of aplysia serotonergic terminals and to examine more directly the transmitter biochemistry of the l29 neurons. |
1983-11-23 |
2023-08-12 |
aplysia |
| H Tamir, W J Kupsky, Y L Huang, M D Gersho. Serotonin-binding glycoprotein of rat platelets. Journal of cell science. vol 62. 1983-11-23. PMID:6352718. |
platelets, because of their ability to take up serotonin, are often considered as models of serotonergic neurons. |
1983-11-23 |
2023-08-12 |
rat |
| E C Azmitia, P M Whitake. Formation of a glial scar following microinjection of fetal neurons into the hippocampus or midbrain of the adult rat: an immunocytochemical study. Neuroscience letters. vol 38. issue 2. 1983-11-23. PMID:6353282. |
the transplanted serotonergic cells, identified by immunocytochemical staining with a primary antibody to serotonin, appeared at the edge of the border but not beyond. |
1983-11-23 |
2023-08-12 |
rat |
| J J Feigenbaum, J Yanai, H L Klawan. The comparative roles of dopaminergic and serotonergic mechanisms in mediating quipazine induced increases in locomotor activity. Journal of neural transmission. vol 57. issue 1-2. 1983-11-23. PMID:6619829. |
though quipazine is generally considered to be a relatively pure serotonergic agonist, its effects on locomotor activity were inhibited by small doses of a centrally acting da receptor blocking agent (haloperidol), while three different serotonergic (5-ht) antagonists were without effect on this behavior. |
1983-11-23 |
2023-08-12 |
rat |