| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M D Gershon, K P Liu, S E Karpiak, H Tami. Storage of serotonin in vivo as a complex with serotonin-binding protein in central and peripheral serotonergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 3. issue 10. 1983-11-23. PMID:6619916. |
storage of serotonin in vivo as a complex with serotonin-binding protein in central and peripheral serotonergic neurons. |
1983-11-23 |
2023-08-12 |
rat |
| M W Yogman, S H Zeise. Diet and sleep patterns in newborn infants. The New England journal of medicine. vol 309. issue 19. 1983-11-23. PMID:6621660. |
sleep behavior is modulated by serotonergic neurons within the brain, and the synthesis and release of serotonin by such neurons is thought to be influenced by the availability of tryptophan, the amino acid precursor of serotonin. |
1983-11-23 |
2023-08-12 |
Not clear |
| M Quik, E Azmiti. Selective destruction of the serotonergic fibers of the fornix-fimbria and cingulum bundle increases 5-HT1 but not 5-HT2 receptors in rat midbrain. European journal of pharmacology. vol 90. issue 4. 1983-10-08. PMID:6884427. |
selected and localized lesions of serotonergic (5-ht) neurons were made by microinjection of 5,7-dihydroxytryptamine (5,7-dht), after pretreatment with desipramine, into the cingulum bundle and fornix-fimbria; these are the major serotonergic hippocampal inputs from the median raphe nucleus. |
1983-10-08 |
2023-08-12 |
rat |
| M Quik, E Azmiti. Selective destruction of the serotonergic fibers of the fornix-fimbria and cingulum bundle increases 5-HT1 but not 5-HT2 receptors in rat midbrain. European journal of pharmacology. vol 90. issue 4. 1983-10-08. PMID:6884427. |
these experiments demonstrate that a selective lesion of the serotonergic system can increase 5-ht1 receptors in the midbrain, which contains the serotonin cell bodies. |
1983-10-08 |
2023-08-12 |
rat |
| N Barden, M Daigle, V Picard, T Di Paol. Perturbation of rat brain serotonergic systems results in an inverse relation between substance P and serotonin concentrations measured in discrete nuclei. Journal of neurochemistry. vol 41. issue 3. 1983-09-23. PMID:6192216. |
perturbation of rat brain serotonergic systems results in an inverse relation between substance p and serotonin concentrations measured in discrete nuclei. |
1983-09-23 |
2023-08-12 |
rat |
| T F Murray, W McGill, D L Chene. A comparison of the analgesic activities of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) and 6-chloro-2[1-piperazinyl]pyrazine (MK 212). European journal of pharmacology. vol 90. issue 2-3. 1983-09-23. PMID:6873180. |
moreover, gaba and serotonin appear to be able to modulate opioid-mediated analgesia in an opposing manner with gabaergic mechanisms facilitating and serotonergic mechanisms inhibiting morphine-induced antinociception. |
1983-09-23 |
2023-08-12 |
mouse |
| B L Jacobs, J Heym, K Rasmusse. Raphe neurons: firing rate correlates with size of drug response. European journal of pharmacology. vol 90. issue 2-3. 1983-09-23. PMID:6873185. |
these data are discussed in terms of an hypothesis which accounts for both the rate of spontaneous activity of serotonergic neurons and the magnitude of their response to serotonin agonist drugs in terms of autoreceptor density on individual neurons. |
1983-09-23 |
2023-08-12 |
Not clear |
| G Gaudin-Chazal, P Portalier, J J Puizillout, D Vigie. Simultaneous visualization of aortic and [3H]5-hydroxytryptamine-accumulating cell bodies in the nodose ganglion of the cat. The Journal of physiology. vol 337. 1983-09-23. PMID:6875933. |
these results show that most aortic neurones are able to take up exogenous serotonin and may be serotonergic neurones. |
1983-09-23 |
2023-08-12 |
cat |
| P Soubrie, C Blas, A Ferron, J Glowinsk. Chlordiazepoxide reduces in vivo serotonin release in the basal ganglia of encéphale isolé but not anesthetized cats: evidence for a dorsal raphe site of action. The Journal of pharmacology and experimental therapeutics. vol 226. issue 2. 1983-09-20. PMID:6410048. |
furthermore, the superfusion of serotonergic nerve terminals of the substantia nigra or the caudate nucleus with chlordiazepoxide (10(-5) m) never altered the local release of [3h]serotonin. |
1983-09-20 |
2023-08-12 |
cat |
| J Behar, P Biancan. Neural control of the sphincter of Oddi. A physiological role of 5-hydroxytryptamine in the regulation of basal sphincter of Oddi motor activity in the cat. The Journal of clinical investigation. vol 72. issue 2. 1983-09-20. PMID:6874956. |
5-ht blockade or depletion resulted in a significant reduction in basal tonic pressures and in the amplitude of phasic contractions, which suggested that serotonergic neurons may play a physiologic role in the regulation of basal so motor activity. |
1983-09-20 |
2023-08-12 |
cat |
| A J Giannini, S Castellani, A E Dvoredsk. Anxiety states: relationship to atmospheric cations and serotonin. The Journal of clinical psychiatry. vol 44. issue 7. 1983-08-26. PMID:6190795. |
the therapeutic response and reduction in serum serotonin after treatment with methysergide and/or removal from the high-cation environment support a serotonergic basis of the anxiety. |
1983-08-26 |
2023-08-12 |
Not clear |
| J A Wallace, J M Laude. Development of the serotonergic system in the rat embryo: an immunocytochemical study. Brain research bulletin. vol 10. issue 4. 1983-08-26. PMID:6344960. |
the development of central serotonergic neurons has been examined immunocytochemically utilizing an antiserum to serotonin (5-ht). |
1983-08-26 |
2023-08-12 |
rat |
| C M Leone, J C de Aguiar, F G Graef. Role of 5-hydroxytryptamine in amphetamine effects on punished and unpunished behaviour. Psychopharmacology. vol 80. issue 1. 1983-08-26. PMID:6408676. |
in order to assess the contribution of serotonergic (5-ht) mechanisms in the suppressant effect of amphetamine on punished responding, dose-effect curves of amphetamine on key-pecking behaviour of pigeons maintained by food presentation and punished by electric-shock were determined before and after pretreatment with methergoline, a potent and specific 5-ht receptor blocker in the central nervous system. |
1983-08-26 |
2023-08-12 |
Not clear |
| R A Browning, J K Smith, M T Brando. Comparison of regional brain 5-HT and 5-HIAA content in flexor and extensor rats. Pharmacology, biochemistry, and behavior. vol 18. issue 4. 1983-08-11. PMID:6191344. |
we have tested the hypothesis that the increased resistance of flexor rats to mes-induced hle is due to elevated serotonergic levels in some region(s) of the cns by examining 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels in 8 regions of the cns in rats classified by mes as either flexors or extensors. |
1983-08-11 |
2023-08-12 |
rat |
| R A Browning, J K Smith, M T Brando. Comparison of regional brain 5-HT and 5-HIAA content in flexor and extensor rats. Pharmacology, biochemistry, and behavior. vol 18. issue 4. 1983-08-11. PMID:6191344. |
no differences in 5-ht, 5-hiaa or 5-htp synthesis rate were detected between flexor and extensor rats for any of the regions examined, suggesting that enhanced serotonergic levels are not responsible for the unusual resistance of flexor rats to hle. |
1983-08-11 |
2023-08-12 |
rat |
| J J Feigenbaum, J Yanai, H L Klawan. Possible dopamine agonist properties of quipazine maleate. The International journal of neuroscience. vol 18. issue 3-4. 1983-08-11. PMID:6222999. |
though quipazine is widely regarded as a relatively pure serotonergic (5-ht) agonist and has been reported to have no dopamine (da) agonist properties, it has produced stereotyped behavior (sb) associated with da agonist arousal of striatal da mechanisms. |
1983-08-11 |
2023-08-12 |
Not clear |
| C Fornal, M Radulovack. Sleep suppressant action of fenfluramine in rats. II. Evidence against the involvement of presynaptic serotonergic mechanism. The Journal of pharmacology and experimental therapeutics. vol 225. issue 3. 1983-08-11. PMID:6223135. |
the present study investigated the involvement of presynaptic serotonergic mechanisms in the sleep suppressant action of fenfluramine, an indirect serotonin (5-ht) receptor agonist. |
1983-08-11 |
2023-08-12 |
rat |
| C Fornal, M Radulovack. Sleep suppressant action of fenfluramine in rats. II. Evidence against the involvement of presynaptic serotonergic mechanism. The Journal of pharmacology and experimental therapeutics. vol 225. issue 3. 1983-08-11. PMID:6223135. |
however, chemical analyses showed that fluoxetine pretreatment completely prevented the depletion of brain 5-ht produced by fenfluramine, suggesting that fenfluramine did not gain entry into serotonergic neurons. |
1983-08-11 |
2023-08-12 |
rat |
| F Moos, P Richar. Serotonergic control of oxytocin release during suckling in the rat: opposite effects in conscious and anesthetized rats. Neuroendocrinology. vol 36. issue 4. 1983-08-11. PMID:6223233. |
5-ht and 5-htp (5-ht precursor) did not affect the milk ejection reflex, whereas serotonergic antagonists and pcpa had an inhibitory effect. |
1983-08-11 |
2023-08-12 |
rat |
| L Valzelli, S Bernasconi, M Dalessandr. Time-courses of p-CPA-induced depletion of brain serotonin and muricidal aggression in the rat. Pharmacological research communications. vol 15. issue 4. 1983-08-11. PMID:6223323. |
with regard to the substance's relatively time-limited effect on brain serotonergic system, the neurochemical activity of p-cpa on tryptophan, serotonin and 5-hydroxyindoleacetic acid on seven discrete areas of the rat brain is studied in parallel to the time-course of muricidal aggression induced by the drug. |
1983-08-11 |
2023-08-12 |
rat |