| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Consolo, H Ladinsky, G L Forloni, P Gromb. Modulation of the hippocampal alpha-adrenoceptor population by lesion of the serotonergic raphe-hippocampal pathway in rats. Life sciences. vol 30. issue 13. 1982-07-08. PMID:6281602. |
electrolytic lesion of the ascending serotonergic fibers in the median raphe nucleus or in both the median raphe nucleus and dorsal raphe nucleus caused after 18 days more than 80% depletion of serotonin in the hippocampus and frontal cortex, respectively, without affecting norepinephrine and acetylcholine contents. |
1982-07-08 |
2023-08-12 |
rat |
| S Auerbach, P Lipto. Vasopressin augments depolarization-induced release and synthesis of serotonin in hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 4. 1982-06-24. PMID:7069467. |
the rat hippocampal slice contains serotonergic nerve terminals but not cell bodies; we studied the effect of vasopressin on the synthesis and release of serotonin from these nerve terminals during depolarization. |
1982-06-24 |
2023-08-12 |
rat |
| M D Gersho. Serotonergic neurotransmission in the gut. Scandinavian journal of gastroenterology. Supplement. vol 71. 1982-06-21. PMID:6122260. |
a specific, high-affinity uptake mechanism for 5-ht is another feature of enteric serotonergic neurons and probably serves as an inactivating mechanism for the amine. |
1982-06-21 |
2023-08-12 |
Not clear |
| T Segawa, M Uehar. Effect of methiothepin on imipramine- or mianserin- induced subsensitivity of serotonergic receptors. Life sciences. vol 30. issue 10. 1982-06-21. PMID:7070196. |
it is suggested that the elevated intrasynaptic 5-ht levels could contribute to potentiation effect of methiothepin on imipramine- or mianserin-induced down regulation of serotonergic receptors. |
1982-06-21 |
2023-08-12 |
rat |
| J Heym, W E Gladfelte. Serotonergic innervation of the lateral hypothalamus: evidence from synaptosomal uptake studies. Brain research bulletin. vol 8. issue 2. 1982-06-14. PMID:6978168. |
fluoxetine, a selective inhibitor of uptake into serotonergic neurons, was a potent inhibitor of serotonin uptake into lateral hypothalamic synaptosomes. |
1982-06-14 |
2023-08-12 |
rat |
| J Heym, W E Gladfelte. Serotonergic innervation of the lateral hypothalamus: evidence from synaptosomal uptake studies. Brain research bulletin. vol 8. issue 2. 1982-06-14. PMID:6978168. |
damage to the ascending serotonergic system, by either electrolytic lesion of the dorsal or median raphe nucleus, or by 5,7 dihydroxytryptamine injections into the midbrain serotonergic pathways, significantly reduced the uptake of serotonin by lateral hypothalamic synaptosomes. |
1982-06-14 |
2023-08-12 |
rat |
| T P Rothman, M D Gersho. Phenotypic expression in the developing murine enteric nervous system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 3. 1982-05-27. PMID:7062117. |
synthesis of [3h] acetylcholine ([3h]ach) from [3h]choline and acetylcholinesterase histochemistry were used as phenotypic markers for cholinergic neurons, while the radioautographic detection of the specific uptake of [3h]serotonin (5-[3h]ht) and immunocytochemical staining with antiserum to 5-ht marked serotonergic neurons. |
1982-05-27 |
2023-08-12 |
mouse |
| L L Martin, R L Bouchal, D J Smit. Ketamine inhibits serotonin uptake in vivo. Neuropharmacology. vol 21. issue 2. 1982-05-21. PMID:6460944. |
these data support the contention that the primary direct effect of ketamine on serotonergic systems is the blockade of 5-ht uptake and that blockade of 5-ht uptake may mediate some of the behavioral effects of ketamine, such as analgesia. |
1982-05-21 |
2023-08-12 |
Not clear |
| J M Murphy, W J McBride, L Lumeng, T K L. Regional brain levels of monoamines in alcohol-preferring and -nonpreferring lines of rats. Pharmacology, biochemistry, and behavior. vol 16. issue 1. 1982-04-12. PMID:6173885. |
in the hy and hip, the 5-ht levels of the p and np animals diverged significantly in opposite directions from those of the stock group, possibly suggesting an involvement of these regional serotonergic systems in alcohol preference. |
1982-04-12 |
2023-08-12 |
rat |
| M Lesiecka, J Cytaw. The effect of intrahypothalamic serotonin reinforcement on directional preference in rats. Acta neurobiologiae experimentalis. vol 41. issue 5. 1982-03-26. PMID:7325021. |
the results did not definitely prove either positive or negative reinforcement produced by the central serotonergic stimulation, although the rats modified their behavior in the maze in the response to intrahypothalamic serotonin. |
1982-03-26 |
2023-08-12 |
rat |
| M Sypniewska, E Przegalińsk. The effect of pyrazidol on the central serotonergic system. Polish journal of pharmacology and pharmacy. vol 33. issue 3. 1982-03-22. PMID:7322945. |
therefore, prz shows characteristics of an agent potentiating serotonergic transmission most probably as the consequence of the inhibition of 5-hydroxytryptamine uptake. |
1982-03-22 |
2023-08-12 |
rat |
| L Valzelli, S Bernasconi, S Garattin. p-Chlorophenylalanine-induced muricidal aggression in male and female laboratory rats. Neuropsychobiology. vol 7. issue 6. 1982-02-25. PMID:6171754. |
judging from the data obtained, the minimal impairment of serotonergic inhibitory control required to induce consistent muricidal aggression in rats of both sexes of the strains considered, corresponds to a brain serotonin depletion of about 55-60%. |
1982-02-25 |
2023-08-12 |
rat |
| D J Goldberg, R T Ambro. Two rates of fast axonal transport of [3H]glycoprotein in an identified invertebrate neuron. Brain research. vol 229. issue 2. 1982-02-22. PMID:6171330. |
recently, the kinetics of fast axonal transport of a single type of organelle, the serotonergic storage vesicle, was described in an identified axon of aplysia using a pulsing technique combined with intracellular injection of [3h]serotonin. |
1982-02-22 |
2023-08-12 |
aplysia |
| E F Zimmerman, E L Wee, N Phillips, N Robert. Presence of serotonin in the palate just prior to shelf elevation. Journal of embryology and experimental morphology. vol 64. 1982-02-22. PMID:7310303. |
since serotonin and its antagonists affect shelf rotation in mouse embryo culture, experiments were carried out to determine whether a serotonergic system is present in the palate. |
1982-02-22 |
2023-08-12 |
mouse |
| R Takahashi, T Tateishi, H Yoshida, H Nagayama, K H Tachik. Serotonin metabolism of animal model of depression. Advances in experimental medicine and biology. vol 133. 1982-02-12. PMID:6172020. |
all results presented here would indicate that serotonin plays an important role in animal behavior such as locomotor depression and that, taking into consideration the effects of antidepressants on 5-ht receptor activity as well as recent biochemical findings of human depression, some forms of human depression could be induced by a cerebral serotonergic receptor hyperactivity contrary to a conventional theory of serotonin deficiency in the synaptic cleft in the brain. |
1982-02-12 |
2023-08-12 |
human |
| G Curzo. Influence of plasma tryptophan on brain 5HT synthesis and serotonergic activity. Advances in experimental medicine and biology. vol 133. 1982-02-12. PMID:7315602. |
influence of plasma tryptophan on brain 5ht synthesis and serotonergic activity. |
1982-02-12 |
2023-08-12 |
human |
| M D Gershon, H Tami. Serotonin binding protein: role in transmitter storage in central and peripheral serotonergic neurons. Advances in experimental medicine and biology. vol 133. 1982-02-12. PMID:7315606. |
serotonin binding protein: role in transmitter storage in central and peripheral serotonergic neurons. |
1982-02-12 |
2023-08-12 |
Not clear |
| R M Bowker, K N Westlund, J D Coulte. Origins of serotonergic projections to the spinal cord in rat: an immunocytochemical-retrograde transport study. Brain research. vol 226. issue 1-2. 1982-01-20. PMID:7028211. |
these findings indicate that the descending serotonin inputs to the spinal cord originate not only from the serotonergic neurons located in the medullary raphe complex, but also from other new sources located in the central gray and reticular formation of the midbrain. |
1982-01-20 |
2023-08-12 |
rat |
| M A Rogawski, G K Aghajania. Serotonin autoreceptors on dorsal raphe neurons: structure-activity relationships of tryptamine analogs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 1. issue 10. 1981-12-21. PMID:6793698. |
the serotonin autoreceptor or so-called "s2 receptor" mediating the inhibition of raphe serotonergic neurons was found to exhibit a high degree of structural specificity among the closely related tryptamine analogs. |
1981-12-21 |
2023-08-12 |
rat |
| T Shimiz. [Effects of peripheral electric stimulation on the central 5-hydroxytryptamine in mice: relation to the peripheral stimulation-produced analgesia (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 77. issue 4. 1981-12-15. PMID:6974679. |
thus, 5-ht neurons are probably excited functionally by the pes, and the mechanisms of analgesia produced by the pes involve both endogenous opiate systems and central serotonergic mechanisms. |
1981-12-15 |
2023-08-12 |
mouse |