| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C H Sawyer, D K Clifto. Aminergic innervation of the hypothalamus. Federation proceedings. vol 39. issue 11. 1980-11-25. PMID:6997091. |
serotonergic (5-ht) neurons project largely from the raphe nuclei, but there are indications of some intrinsic 5-ht cells. |
1980-11-25 |
2023-08-12 |
Not clear |
| R S Sloviter, J D Connor, B P Damiano, E G Drus. Para-halogenated phenethylamines: similar serotonergic effects in rats by different mechanisms. Pharmacology, biochemistry, and behavior. vol 13. issue 2. 1980-11-24. PMID:6447879. |
the serotonin (5-ht) behavioral syndrome in rats served as a model to test for possible acute serotonergic effects of para-halogenated phenethylamines. |
1980-11-24 |
2023-08-12 |
rat |
| R S Sloviter, J D Connor, B P Damiano, E G Drus. Para-halogenated phenethylamines: similar serotonergic effects in rats by different mechanisms. Pharmacology, biochemistry, and behavior. vol 13. issue 2. 1980-11-24. PMID:6447879. |
pretreatment of rats with the 5-ht depletor p-chlorophenylalanine (pcpa)( prevented the serotonergic effects of both chloro-derivatives, and partially prevented the effects of bromo- and iodophenethylamine. |
1980-11-24 |
2023-08-12 |
rat |
| R S Sloviter, J D Connor, B P Damiano, E G Drus. Para-halogenated phenethylamines: similar serotonergic effects in rats by different mechanisms. Pharmacology, biochemistry, and behavior. vol 13. issue 2. 1980-11-24. PMID:6447879. |
similarly, zimelidine, a 5-ht uptake inhibitor, prevented the serotonergic behavioral effects of all compounds tested except p-fluorophenethylamine. |
1980-11-24 |
2023-08-12 |
rat |
| R S Sloviter, J D Connor, B P Damiano, E G Drus. Para-halogenated phenethylamines: similar serotonergic effects in rats by different mechanisms. Pharmacology, biochemistry, and behavior. vol 13. issue 2. 1980-11-24. PMID:6447879. |
taken as a group, para-halogenated phenethylamines are short-acting serotonergic compounds which, unlike p-chloroamphetamine, do not produce long-lasting depletion of brain 5-ht. |
1980-11-24 |
2023-08-12 |
rat |
| S Araneda, P Bobillier, M Buda, J F Pujo. Retrograde axonal transport following injection of [3H]serotonin in the olfactory bulb. I. Biochemical study. Brain research. vol 196. issue 2. 1980-10-24. PMID:6156739. |
a retrograde axonal transport from the serotonergic nerve terminals in the olfactory bulb (ob) to their parent cell bodies in the midbrain raphe nuclei has been demonstrated after stereotaxic injection of [2h]5-ht into the ob of rats pretreated with a monoamine oxidase (mao) inhibitor: at various time intervals thereafter (4-92 h) there was a preferential accumulation of radioactivity mainly in the raphe dorsalis nucleus (rdn). |
1980-10-24 |
2023-08-12 |
rat |
| S Araneda, P Bobillier, M Buda, J F Pujo. Retrograde axonal transport following injection of [3H]serotonin in the olfactory bulb. I. Biochemical study. Brain research. vol 196. issue 2. 1980-10-24. PMID:6156739. |
destruction of serotonergic nerve terminals by 5,6-dihydroxytryptamine or inhibiton of 5-ht uptake by fluoxetine decreased this retrograde accumulation whereas destruction of catecholaminergic nerve terminals by 6-hydroxydopamine was without effect. |
1980-10-24 |
2023-08-12 |
rat |
| S Araneda, P Bobillier, M Buda, J F Pujo. Retrograde axonal transport following injection of [3H]serotonin in the olfactory bulb. I. Biochemical study. Brain research. vol 196. issue 2. 1980-10-24. PMID:6156739. |
in conclusion, the retrograde axonal transport following [3h]5-ht injection in the serotonergic rdn-ob system occurs via an active process which depends on a colchicine-sensitive mechanism and is partially linked to a reserp ine-sensitive structure. |
1980-10-24 |
2023-08-12 |
rat |
| S Araneda, H Gamrani, C Font, A Calas, J F Pujol, P Bobillie. Retrograde axonal transport following injection of [3H]-serotonin into the olfactory bulb. II. Radioautographic study. Brain research. vol 196. issue 2. 1980-10-24. PMID:6156740. |
radioautography was used to study the intraneuronal distribution of [3h]-serotonin (5-ht) and/or its derivatives selectively taken up by the olfactory bulb (ob) serotonergic terminals and subsequently transported to their parent cell bodies in the midbrain raphe nuclei. |
1980-10-24 |
2023-08-12 |
rat |
| D M Kuhn, W A Wolf, W Lovenber. Pressor effects of electrical stimulation of the dorsal and median raphe nuclei in anesthetized rats. The Journal of pharmacology and experimental therapeutics. vol 214. issue 2. 1980-09-28. PMID:6104727. |
taken together, these data suggest that stimulation of the ascending serotonergic neuronal system produces a phasic pressor effect which is mediated, at least in part, by synaptic serotonin. |
1980-09-28 |
2023-08-12 |
rat |
| D M Kuhn, W A Wolf, W Lovenber. Review of the role of the central serotonergic neuronal system in blood pressure regulation. Hypertension (Dallas, Tex. : 1979). vol 2. issue 3. 1980-09-28. PMID:6446522. |
the ability of brain serotonin to modulate arterial blood pressure may be mediated by the influences of the serotonergic neuronal systems on efferent sympathetic activity. |
1980-09-28 |
2023-08-12 |
rat |
| R S Ehsanulla. Uptake of 5-hydroxytryptamine and dopamine into platelets from depressed patients and normal subjects--influence of clomipramine, desmethylclomipramine and maprotiline. Postgraduate medical journal. vol 56 Suppl 1. 1980-09-23. PMID:7393826. |
clomipramine potently inhibits platelet uptake of da as well as 5-ht, its antidepressant action cannot be attributed to 5-ht alone, while the observation that maprotiline has no effect on 5-ht uptake shows that its antidepressant action is not based on a serotonergic mechanism. |
1980-09-23 |
2023-08-12 |
human |
| K Andreas, C Dude, G Dud. Interaction of morphine and 5-hydroxytryptamine in the raphe-hippocampus system. Polish journal of pharmacology and pharmacy. vol 31. issue 5. 1980-08-25. PMID:547279. |
in order to describe the interaction of morphine and 5-hydroxytryptamine (5-ht) in the raphe-hippocampus system we tested the influence on the antinocifensive effect of topic administrations of morphine and serotonergic substances into the dorsal hippocampus and the median raphe nucleus in rats. |
1980-08-25 |
2023-08-11 |
rat |
| M S Salles, K S Salle. Behavioral effect of selective and non-selective lesions of median raphe nucleus in the rat. The Japanese journal of physiology. vol 30. issue 1. 1980-08-15. PMID:7382190. |
the role of the serotonergic (5-ht) system in the regulation of locomotor activity and consummatory behaviors was studied. |
1980-08-15 |
2023-08-12 |
rat |
| K Tsurumi, K Yasuda, E Maki, H Fujimur. [Effect of spasmolytics on cathartic activity of pilocarpine, 5-HT and prostaglandlin E2 in mice (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 75. issue 8. 1980-07-12. PMID:544395. |
it is suggested that 5-ht has dual sites of actions and there are less cholinergic and specific serotonergic actions. |
1980-07-12 |
2023-08-11 |
mouse |
| J P Huidobro-Toro, B Fore. Dual agonist-antagonist effects of 5-hydroxytryptamine (5-HT) in the guinea pig ileum: evidence for a selective receptor desensitization effect. European journal of pharmacology. vol 61. issue 4. 1980-07-12. PMID:6102916. |
the auto-blockade of the 5-ht responses was selective to drugs acting on serotonergic receptors. |
1980-07-12 |
2023-08-12 |
Not clear |
| E J Catapane, E D Collins, J A Marcano, G B Stefan. Denervation produces supersensitivity of a serotonergically innervated structure. European journal of pharmacology. vol 62. issue 1. 1980-07-12. PMID:7371719. |
lateral ciliary activity which is under excitatory serotonergic control displayed an increased response to superfusion with serotonin after both treatment, as compared to controls. |
1980-07-12 |
2023-08-12 |
Not clear |
| E Chung Hwang, M H Van Woer. Comparative effects of substituted phenylethylamines on brain serotonergic mechanisms. The Journal of pharmacology and experimental therapeutics. vol 213. issue 2. 1980-06-27. PMID:6965983. |
the ability of phenylethylamine derivatives to release preferentially [3h]serotonin in vitro without damaging serotonergic neurons and to consistently and rapidly produce the serotonin syndrome in vivo should make these compounds useful pharmacological tools for investigating brain serotonin metabolism. |
1980-06-27 |
2023-08-12 |
mouse |
| A R Gintzler, T P Rothman, M D Gersho. Ontogeny of opiate mechanisms in relation to the sequential development of neurons known to be components of the guinea pig's enteric nervous system. Brain research. vol 189. issue 1. 1980-06-25. PMID:6244879. |
neuronal precursors, however, are probably present prior to 25 days and putative serotonergic precursors were recognizable by their uptake of [3h]5-ht into cell bodies as early as day 20. |
1980-06-25 |
2023-08-12 |
Not clear |
| B Oderfeld-Nowak, J R Simon, L Chang, M H Apriso. Interactions of the cholinergic and serotonergic systems: re-evaluation of conditions for inhibition of acetylcholinesterase by serotonin and evidence for a new inhibitor derived from this natural indoleamine. General pharmacology. vol 11. issue 1. 1980-06-25. PMID:7364202. |
interactions of the cholinergic and serotonergic systems: re-evaluation of conditions for inhibition of acetylcholinesterase by serotonin and evidence for a new inhibitor derived from this natural indoleamine. |
1980-06-25 |
2023-08-12 |
Not clear |