| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E C Hwang, M H Van Woer. p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus. Neurology. vol 28. issue 10. 1979-05-23. PMID:311446. |
drugs that enhance brain serotonergic activity reduced p,p'-ddt-induced myoclonus, and serotonin antagonists invariably aggravated this syndrome. |
1979-05-23 |
2023-08-11 |
mouse |
| P Bernd, M D Gershon, E A Nunez, H Tami. Localization of a highly specific neuronal protein, serotonin binding protein, in thyroid parafollicular cells. The Anatomical record. vol 193. issue 2. 1979-05-23. PMID:426298. |
a highly specific serotonin binding protein (sbp) has been found in serotonergic neurons in both brain and gut. |
1979-05-23 |
2023-08-11 |
Not clear |
| K Ajika, J Och. Serotonergic projections to the suprachiasmatic nucleus and the median eminence of the rat: identification by fluorescence and electron microscope. Journal of anatomy. vol 127. issue Pt 3. 1979-05-23. PMID:744749. |
the present study suggests that the serotonergic terminals exert their influence on the anterior pituitary function, not only at the level of the suprachiasmatic nucleus, but also at the level of the perivascular region of the median eminence, either through the axo-axonic synapses with the axons containing the releasing hormone or by the direct release of 5-ht into the portal vessels. |
1979-05-23 |
2023-08-11 |
rat |
| M T Li. Effects of specific inhibitors of 5-hydroxytryptamine uptake on thermoregulation in rats. The Journal of physiology. vol 284. 1979-03-28. PMID:310457. |
the data suggest that an increase in serotonergic receptor activity or in functional serotonin in brain decreases heat production and/or increases heat loss and leads to hypothermia in rats. |
1979-03-28 |
2023-08-11 |
rat |
| V J Massari, Y Tizabi, D M Jacobowit. Potential noradrenergic regulation of serotonergic neurons in the median raphe nucleus. Experimental brain research. vol 34. issue 1. 1979-03-28. PMID:759225. |
serotonin levels in the median raphe nucleus were significantly reduced by 40%, but levels of serotonin were unaffected in the dorsal raphe nucleus and 8 serotonergic terminal regions. |
1979-03-28 |
2023-08-11 |
rat |
| N M Bhakthan, S Chi. Deranged diurnal feeding pattern and altered brain serotonin turnover in heroin-dependent rats. Archives internationales de pharmacodynamie et de therapie. vol 235. issue 2. 1979-03-24. PMID:570026. |
the results obtained in this study indicate that whereas the perturbed diurnal feeding activity cannot be ascribed exclusively to altered central serotonergic mechanism, chronic heroin treatment appears to decrease the rate of serotonin via a negative feedback loop. |
1979-03-24 |
2023-08-11 |
rat |
| F A Curro, S Greenberg, T J Verbeuren, P M Vanhoutt. Interaction between alpha adrenergic and serotonergic activation of canine saphenous veins. The Journal of pharmacology and experimental therapeutics. vol 207. issue 3. 1979-03-13. PMID:215746. |
these findings suggest that serotonin does not contract canine saphenous veins by stimulation of typical serotonergic receptors. |
1979-03-13 |
2023-08-11 |
Not clear |
| H J Haigle. Morphine: effects on serotonergic neurons and neurons in areas with a serotonergic input. European journal of pharmacology. vol 51. issue 4. 1979-01-26. PMID:710510. |
the hypothesis that morphine acts on the serotonergic system to produce analgesia is based on the previous observations that (1) lesions and stimulation of midbrain raphe nuclei after the threshold to nociceptive stimuli; (2) morphine alters the turnover of serotonin (5-hydroxytryptamine; 5-ht). |
1979-01-26 |
2023-08-11 |
Not clear |
| H J Haigle. Morphine: effects on serotonergic neurons and neurons in areas with a serotonergic input. European journal of pharmacology. vol 51. issue 4. 1979-01-26. PMID:710510. |
microiontophoretic experiments were carried out to determine if morphine affected the firing rate of cells in five areas of the serotonergic system consisting of 5-ht containing neurons in the midbrain raphe nuclei (dorsal raphe and median raphe) or neurons in three areas (amygdala, optic tectum and subiculum) which are thought to receive a 5-ht input from the raphe nuclei. |
1979-01-26 |
2023-08-11 |
Not clear |
| H J Haigle. Morphine: effects on serotonergic neurons and neurons in areas with a serotonergic input. European journal of pharmacology. vol 51. issue 4. 1979-01-26. PMID:710510. |
it is concluded that (1) the analgesic effect of morphine is not related to an effect on neurons in the midbrain raphe nuclei and three areas which receive an identified 5-ht input; and (2) the effect of morphine on neurons in these five areas of the serotonergic system is not a specific narcotic effect. |
1979-01-26 |
2023-08-11 |
Not clear |
| D J Goldberg, J H Schwartz, A A Sherban. Kinetic properties of normal and perturbed axonal transport of serotonin in a single identified axon. The Journal of physiology. vol 281. 1978-12-27. PMID:81302. |
the axonal transport of pulses of [3h]serotonin was studied in an axon of the serotonergic giant cerebral neurone (gcn) of aplysia californica. |
1978-12-27 |
2023-08-11 |
aplysia |
| M Ogaw. Interaction between noradrenergic and serotonergic mechanisms on the central regulation of blood pressure in the rat: a study using experimental central hypertension produced by chemical lesions of the locus coeruleus. Japanese circulation journal. vol 42. issue 5. 1978-12-27. PMID:151755. |
the results of these experiments demonstrate that (1) lc hypertension is probably due to a specific lesion of the lc with 6-ohda, (2) lc hypertension is accompanied by an increase of 5-ht turnover in the cortex and especially in the spinal cord, which may participate in a depressor function in lc hypertension, (3) ablation of bulbospinal serotonergic neurons produce mild elevation in blood pressure. |
1978-12-27 |
2023-08-11 |
rat |
| R F Martin, L M Jordan, W D Willi. Differential projections of cat medullary raphe neurons demonstrated by retrograde labelling following spinal cord lesions. The Journal of comparative neurology. vol 182. issue 1. 1978-12-27. PMID:701490. |
the serotonergic (5ht) fibers described by dahlström and fuxe ('65) to terminate in the dorsal horn, intermediolateral cell column, and ventral horn are likely to coincide with the raphe-spinal projections documented in this work. |
1978-12-27 |
2023-08-11 |
cat |
| R Bessone, L Segu, A Cala. Radioautographic identification of serotonergic neurones in Aplysia. Experientia. vol 34. issue 8. 1978-12-20. PMID:700018. |
radioautography shows that 3h 5-ht specifically labels metacerebral and 2 other serotonergic cell bodies in aplysia cerebroid ganglia as well as 5-ht terminals in close contact with giant neurone membrane in buccal ganglia. |
1978-12-20 |
2023-08-11 |
aplysia |
| J P Chalmers, L M Win. Central serotonergic neurons and experimental neurogenic and renal hypertension in the rabbit. Clinical science and molecular medicine. Supplement. vol 2. 1978-12-02. PMID:1077778. |
rabbits received intracisternal injections of 5,6-dihydroxytryptamine (5,6-dht) in order to ablate central serotonergic nerves and deplete central serotonin stores. |
1978-12-02 |
2023-08-11 |
rabbit |
| R B Rastogi, R L Singha. The effect of thyroid hormone on serotonergic neurones: depletion of serotonin in discrete brain areas of developing hypothyroid rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 304. issue 1. 1978-11-29. PMID:692746. |
the effect of thyroid hormone on serotonergic neurones: depletion of serotonin in discrete brain areas of developing hypothyroid rats. |
1978-11-29 |
2023-08-11 |
rat |
| S K Bhattacharya, P R Keshary, A K Sanya. Immobilisation stress-induced antinociception in rats: possible role of serotonin and prostaglandins. European journal of pharmacology. vol 50. issue 1. 1978-10-18. PMID:150334. |
antinociception induced by 4 h immobilisation was significantly inhibited after pretreatment by drugs known to inhibit synthesis of serotonin, induce degeneration of serotonergic neurones and inhibit prostaglandin synthesis. |
1978-10-18 |
2023-08-11 |
rat |
| J S Meyer, N S Buckholtz, W O Bogga. Serotonergic stimulation of pituitary-adrenal activity in the mouse. Neuroendocrinology. vol 26. issue 5. 1978-10-18. PMID:150549. |
it is concluded that (1) 5-htp stimulates pituitary-adrenal activity in mice by being converted to 5-ht and acting on 1 or more groups of serotonergic receptors; (2) these receptors are located either in an area of the brain outside of the blood-brain barrier such as the median eminence or in a peripheral tissue(s); (3) tryptophan-derived 5-ht can stimulate these receptors, but only if allowed to accumulate by inhibiting its catabolism; and (4) it is not yet clear whether pituitary-adrenal responses to quipazine and 6-meo-thbc are mediated by a serotonergic mechanism. |
1978-10-18 |
2023-08-11 |
mouse |
| G S Omenn, L T Smit. A common uptake system for serotonin and dopamine in human platelets. The Journal of clinical investigation. vol 62. issue 2. 1978-09-15. PMID:670392. |
uptake of serotonin into platelets closely resembles reuptake of serotonin into serotonergic neurons. |
1978-09-15 |
2023-08-11 |
human |
| J D Lane, M H Apriso. The flux of radioactive label through components of the serotonergic system following the injection of [3H]tryptophan: product--precursor anomalies providing evidence that serotonin exists in multiple pools. Journal of neurochemistry. vol 30. issue 4. 1978-07-26. PMID:650211. |
the flux of radioactive label through components of the serotonergic system following the injection of [3h]tryptophan: product--precursor anomalies providing evidence that serotonin exists in multiple pools. |
1978-07-26 |
2023-08-11 |
Not clear |