| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Cudennec, D Duverger, T Nishikawa, A McRae-Degueurce, E T MacKenzie, B Scatto. Influence of ascending serotonergic pathways on glucose use in the conscious rat brain. I. Effects of electrolytic or neurotoxic lesions of the dorsal and/or median raphé nucleus. Brain research. vol 444. issue 2. 1988-06-02. PMID:3359293. |
two hypotheses are advanced for this lack of change: firstly, the chronic reduction of 5-hydroxytryptamine levels is accompanied by compensatory changes in this or other neurotransmitter systems; secondly, serotonergic neurones may exert a phasic--rather than tonic--influence on glucose use in the mammalian brain. |
1988-06-02 |
2023-08-11 |
rat |
| A Cudennec, D Duverger, A Serrano, B Scatton, E T MacKenzi. Influence of ascending serotonergic pathways on glucose use in the conscious rat brain. II. Effects of electrical stimulation of the rostral raphé nuclei. Brain research. vol 444. issue 2. 1988-06-02. PMID:3359294. |
the magnitude and pattern of the increases in glucose use could not always be correlated with the regional density of serotonergic innervation nor with the distribution of 5-hydroxytryptamine receptor subtypes in the adult brain. |
1988-06-02 |
2023-08-11 |
rat |
| A I Basbaum, K Zahs, B Lord, S Lako. The fiber caliber of 5-HT immunoreactive axons in the dorsolateral funiculus of the spinal cord of the rat and cat. Somatosensory research. vol 5. issue 3. 1988-05-13. PMID:3358043. |
although there is considerable evidence that the analgesic action of electrical brain stimulation is mediated in part by serotonergic (5-ht) axons in the dorsolateral funiculus (dlf) of the spinal cord, studies in the rat have questioned the existence of this pathway. |
1988-05-13 |
2023-08-11 |
rat |
| E H Jaffe, M Urbina, C Ayala, M E Chemell. Serotonin containing neurons in the retina of the teleost Eugerres plumieri. Vision research. vol 27. issue 12. 1988-05-13. PMID:3447354. |
this is the first direct evidence that serotonin is apparently present in amacrine cells of the retina of e. plumieri with a distribution of the serotonergic terminals similar to goldfish but somewhat different when compared to other species. |
1988-05-13 |
2023-08-11 |
Not clear |
| R A Glennon, M Titeler, R A Lyon, R M Slushe. N,N-di-n-propylserotonin: binding at serotonin binding sites and a comparison with 8-hydroxy-2-(di-n-propylamino)tetralin. Journal of medicinal chemistry. vol 31. issue 4. 1988-05-10. PMID:2965244. |
8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) is a serotonergic agonist with high affinity and selectivity for a particular population of central serotonin (5-ht) binding sites (i.e., 5-ht1a sites). |
1988-05-10 |
2023-08-11 |
rat |
| A L Ask, S B Ros. Inhibition of 5-hydroxytryptamine accumulation and deamination by substituted phenylalkylamines in hypothalamic synaptosomes from normal and reserpine-pretreated rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 6. 1988-05-03. PMID:2965308. |
in the present study the abilities of different compounds to inhibit mao inside and outside the serotonergic neurons, to inhibit the accumulation of 5-ht and to release 5-ht were separated by using different in vitro techniques. |
1988-05-03 |
2023-08-11 |
rat |
| A L Ask, S B Ros. Inhibition of 5-hydroxytryptamine accumulation and deamination by substituted phenylalkylamines in hypothalamic synaptosomes from normal and reserpine-pretreated rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 336. issue 6. 1988-05-03. PMID:2965308. |
most of the phenylalkylamines were slightly more potent as mao inhibitors outside serotonergic synaptosomes than as inhibitors of 5-ht accumulation in normal rats. |
1988-05-03 |
2023-08-11 |
rat |
| J Y Chang, J E Hardebo, C Owman, C Sahlin, N A Svendgaar. Nerves containing serotonin, its interaction with noradrenaline, and characterization of serotonin receptors in cerebral arteries of monkey. Journal of autonomic pharmacology. vol 7. issue 4. 1988-05-02. PMID:3443601. |
1 immunohistochemistry was applied to study the presence of 5-hydroxytryptamine (5-ht) and dopamine-beta-hydroxylase (dbh) in cerebrovascular nerves of monkeys, and serotonergic receptors were characterized in the vessels by in vitro pharmacology. |
1988-05-02 |
2023-08-11 |
monkey |
| K Drescher, L Hete. Influence of antipsychotics and serotonin antagonists on presynaptic receptors modulating the release of serotonin in synaptosomes of the nucleus accumbens of rats. Neuropharmacology. vol 27. issue 1. 1988-04-22. PMID:2895429. |
the experimental system (the k+-stimulated synaptosomal release of [3h]5-ht seems to be a suitable model for differentiating dopaminergic and/or serotonergic components of antipsychotics or other drugs on presynaptic receptors. |
1988-04-22 |
2023-08-11 |
rat |
| N W Hoffman, A A Gerall, P W Kaliva. Sexual refractoriness and locomotion effects on brain monoamines in the male rat. Physiology & behavior. vol 41. issue 6. 1988-04-18. PMID:2450382. |
the results suggest that the mpoa is a forebrain target for inhibitory influences on male rat sexual behavior of ascending serotonergic fibers and that increased mfb 5-ht and mpoa da may be associated with general activity. |
1988-04-18 |
2023-08-11 |
rat |
| M Davis, J V Cassella, J H Kehn. Serotonin does not mediate anxiolytic effects of buspirone in the fear-potentiated startle paradigm: comparison with 8-OH-DPAT and ipsapirone. Psychopharmacology. vol 94. issue 1. 1988-04-18. PMID:2894698. |
taken together, the data do not support the hypothesis that buspirone's anxiolytic effects are mediated by actions at 5-ht 1a receptors and more generally indicate that serotonergic neurons do not play an important role in fear-potentiated startle. |
1988-04-18 |
2023-08-11 |
Not clear |
| W J Brooks, M F Jarvis, G C Wagne. Attenuation of MPTP-induced dopaminergic neurotoxicity by a serotonin uptake blocker. Journal of neural transmission. vol 71. issue 2. 1988-04-18. PMID:3258013. |
in keeping with its demonstrated ability to inhibit uptake into serotonergic neurons and serotonin uptake into astrocytes, fluoxetine pretreatment resulted in a significant attenuation of mptp-induced depletions of striatal dopamine and serotonin concentration. |
1988-04-18 |
2023-08-11 |
Not clear |
| J Y Chang, C Owman, H W Steinbusc. Evidence for coexistence of serotonin and noradrenaline in sympathetic nerves supplying brain vessels of guinea pig. Brain research. vol 438. issue 1-2. 1988-04-18. PMID:3345430. |
small intensive fluorescent cells with positive immunoreaction for 5-ht and dbh, respectively, were located in clusters within the ganglion, which showed no immunohistochemical evidence for the presence of serotonergic neurons. |
1988-04-18 |
2023-08-11 |
Not clear |
| J Y Chang, C Owman, H W Steinbusc. Evidence for coexistence of serotonin and noradrenaline in sympathetic nerves supplying brain vessels of guinea pig. Brain research. vol 438. issue 1-2. 1988-04-18. PMID:3345430. |
it is concluded that 5-ht is probably not synthesized in truly serotonergic fibers but rather taken up and stored together with noradrenaline in cerebrovascular sympathetic nerves originating in the superior cervical ganglia. |
1988-04-18 |
2023-08-11 |
Not clear |
| D L Armstrong, M Hay, D M Terria. Modulation of cerebellar granule cell activity by iontophoretic application of serotonergic agents. Brain research bulletin. vol 19. issue 6. 1988-04-15. PMID:2894237. |
the variable effects of serotonin on spontaneous activity suggests the presence of more than one type of serotonergic receptor in the cerebellar granule cell layer. |
1988-04-15 |
2023-08-11 |
rat |
| L R Levine, S Rosenblatt, J Bosomwort. Use of a serotonin re-uptake inhibitor, fluoxetine, in the treatment of obesity. International journal of obesity. vol 11 Suppl 3. 1988-04-12. PMID:3501994. |
fluoxetine is a specific inhibitor of serotonin re-uptake with very minimal affinity for serotonergic or other receptors. |
1988-04-12 |
2023-08-11 |
Not clear |
| A Berger, A J Ramire. Hypotensive spinal serotonergic effect. Are S1 or S2 receptors involved? Hypertension (Dallas, Tex. : 1979). vol 11. issue 2 Pt 2. 1988-04-11. PMID:3346054. |
the results showed that the dose-dependent decrease in mean blood pressure induced by serotonin administered at the t6-l3 level was prevented by giving the serotonergic s2 antagonist ritanserin intravenously. |
1988-04-11 |
2023-08-11 |
rat |
| A Berger, A J Ramire. Hypotensive spinal serotonergic effect. Are S1 or S2 receptors involved? Hypertension (Dallas, Tex. : 1979). vol 11. issue 2 Pt 2. 1988-04-11. PMID:3346054. |
the results suggest that the hypotensive effect obtained after the spinal serotonergic activation involves serotonin receptors of the s2 type. |
1988-04-11 |
2023-08-11 |
rat |
| G E DeLander, C J Hopkin. Interdependence of spinal adenosinergic, serotonergic and noradrenergic systems mediating antinociception. Neuropharmacology. vol 26. issue 12. 1988-04-07. PMID:3437941. |
interactions observed when serotonergic and adenosinergic agents were coadministered suggest that antinociception induced by serotonin (i.t.) |
1988-04-07 |
2023-08-11 |
mouse |
| U Traversa, P Puppini, C Florio, R Vertu. Effects of an atypical barbiturate (valofan) on spontaneous and stimulated locomotor activity and on brain serotonin metabolism in mice. Il Farmaco; edizione scientifica. vol 42. issue 10. 1988-03-25. PMID:2449358. |
some serotonergic agents were employed in order to evaluate the possible involvement of serotonin on its mechanism of action. |
1988-03-25 |
2023-08-11 |
mouse |