| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Cohe. Inhibition of adrenergic neurotransmission in canine tibial artery after exposure to 5-hydroxytryptamine in vitro. The Journal of pharmacology and experimental therapeutics. vol 242. issue 2. 1987-09-23. PMID:3039118. |
the inhibition of [3h]norepinephrine release after exposure to 5-hydroxytryptamine, was blocked by the serotonergic antagonist, methiothepin, but not by the alpha adrenergic antagonist, phentolamine, suggesting that serotonergic receptors mediate the inhibition. |
1987-09-23 |
2023-08-11 |
dog |
| Y F Chen, H K Jin, R Gist, S Opari. Blunted responsiveness of posterior hypothalamic norepinephrine to quinpirole in DOCA/NaCl hypertensive rats. Brain research bulletin. vol 18. issue 4. 1987-09-03. PMID:2440528. |
to examine the hypothesis that the responsiveness of the central noradrenergic and serotonergic systems to quinpirole treatment is altered in doca/nacl rats, the norepinephrine (ne), serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) contents of hypothalamic and brainstem areas were measured in 4-week doca/nacl hypertensive and h2o control rats 15 minutes after the intravenous administration of quinpirole (1 mg/kg). |
1987-09-03 |
2023-08-11 |
rat |
| P M Whitaker-Azmitia, J M Lauder, A Shemmer, E C Azmiti. Postnatal changes in serotonin receptors following prenatal alterations in serotonin levels: further evidence for functional fetal serotonin receptors. Brain research. vol 430. issue 2. 1987-09-01. PMID:2955853. |
furthermore, since 5-ht has a dual role in neuronal development, these receptors must be functional both in the region of the serotonergic cell body (brainstem) and in projection areas (forebrain). |
1987-09-01 |
2023-08-11 |
rat |
| D Wirtshafter, M A Klitenick, K E Asi. Evidence against serotonin involvement in the hyperactivity produced by injections of muscimol into the median raphe nucleus. Pharmacology, biochemistry, and behavior. vol 27. issue 1. 1987-08-28. PMID:2441421. |
furthermore, hyperactivity could not be produced by intra-median raphe injections of serotonin or of fenfluramine, compounds which would be expected to inhibit serotonergic raphe cells. |
1987-08-28 |
2023-08-11 |
rat |
| F C Zhou, S Auerbach, E Azmiti. Denervation of serotonergic fibers in the hippocampus induced a trophic factor which enhances the maturation of transplanted serotonergic neurons but not norepinephrine neurons. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037093. |
the trophic effects of specific denervation on the growth and survival of fetal serotonergic (5-ht) or norepinephrinergic (ne) neurons grafted into the hippocampus were assessed by means of two transplantation paradigms. |
1987-08-11 |
2023-08-11 |
Not clear |
| R B Innis, D S Charney, G R Heninge. Differential 3H-imipramine platelet binding in patients with panic disorder and depression. Psychiatry research. vol 21. issue 1. 1987-08-10. PMID:3037580. |
because 3h-imi binding is associated with the serotonin reuptake site in platelet and brain membranes, these findings give further support to abnormalities in serotonergic function in patients with major depression. |
1987-08-10 |
2023-08-11 |
human |
| A Pazos, A Probst, J M Palacio. Serotonin receptors in the human brain--III. Autoradiographic mapping of serotonin-1 receptors. Neuroscience. vol 21. issue 1. 1987-08-05. PMID:2955249. |
the anatomical distribution of serotonin-1a and serotonin-1c receptors is discussed taking into account the distribution of serotonergic neurons and fibres, the central functions in which serotonin appears to be involved and the characteristics of the neurological and psychiatric disorders where changes in brain serotonin-1 receptors have been reported. |
1987-08-05 |
2023-08-11 |
human |
| J G Bernstei. Induction of obesity by psychotropic drugs. Annals of the New York Academy of Sciences. vol 499. 1987-07-30. PMID:2886102. |
because many antidepressants, including trazodone and amitriptyline, the neuroleptic, chlorpromazine, and the mood stabilizer, lithium, may all, under some circumstances, inhibit serotonin reuptake mechanisms and may simultaneously block serotonin receptor sites, their effects on appetite and weight gain may represent a balance between serotonergic and antiserotonin activities. |
1987-07-30 |
2023-08-11 |
Not clear |
| H W Steinbusch, A Beek, A L Frankhuyzen, J A Tonnaer, F H Gage, A Björklun. Functional activity of raphe neurons transplanted to the hippocampus and caudate-putamen. An immunohistochemical and neurochemical analysis in adult and aged rats. Annals of the New York Academy of Sciences. vol 495. 1987-07-29. PMID:3474940. |
results showed that after a survival time of 10 weeks, the serotonergic innervation of the hippocampus was greatly restored and, moreover, that the k+-induced ca2+-dependent release of 5-ht amounted to about 80% of normal values. |
1987-07-29 |
2023-08-11 |
rat |
| H W Steinbusch, A Beek, A L Frankhuyzen, J A Tonnaer, F H Gage, A Björklun. Functional activity of raphe neurons transplanted to the hippocampus and caudate-putamen. An immunohistochemical and neurochemical analysis in adult and aged rats. Annals of the New York Academy of Sciences. vol 495. 1987-07-29. PMID:3474940. |
there appeared to be a striking similarity between the immunohistochemical and neurochemical data regarding the increase in the number of newly formed serotonergic fibers, the increase of the release of radiolabeled 5-ht, and the extent of the outgrowth in the hippocampus. |
1987-07-29 |
2023-08-11 |
rat |
| F J Miñano, M Sancibrián, J S Serran. Hypothermic effect of GABA in conscious restrained rats and its modification by monoaminergic blocking drugs. Methods and findings in experimental and clinical pharmacology. vol 9. issue 4. 1987-07-29. PMID:3600097. |
injection of gaba could be due to release of serotonin by activation of bicuculline-insensitive gaba receptors located on central serotonergic neurons. |
1987-07-29 |
2023-08-11 |
rat |
| C J Schmid. Acute administration of methylenedioxymethamphetamine: comparison with the neurochemical effects of its N-desmethyl and N-ethyl analogs. European journal of pharmacology. vol 136. issue 1. 1987-07-24. PMID:2885204. |
the effects of the latter two drugs were correlated with a significant decrease in whole brain synaptosomal [3h]5ht uptake indicating serotonergic nerve terminal damage. |
1987-07-24 |
2023-08-11 |
rat |
| L O Wilkinson, E D Abercrombie, K Rasmussen, B L Jacob. Effect of buspirone on single unit activity in locus coeruleus and dorsal raphe nucleus in behaving cats. European journal of pharmacology. vol 136. issue 1. 1987-07-24. PMID:3595712. |
the effects of administration of the non-benzodiazepine anxiolytic buspirone on the spontaneous and sensory evoked single unit activity of serotonergic (5-ht) neurons in the dorsal raphe nucleus and noradrenergic (ne) neurons in the locus coeruleus were examined in freely moving cats. |
1987-07-24 |
2023-08-11 |
Not clear |
| R J D'Amato, M E Blue, B L Largent, D R Lynch, D J Ledbetter, M E Molliver, S H Snyde. Ontogeny of the serotonergic projection to rat neocortex: transient expression of a dense innervation to primary sensory areas. Proceedings of the National Academy of Sciences of the United States of America. vol 84. issue 12. 1987-07-17. PMID:3473503. |
the development of serotonergic innervation to rat cerebral cortex was characterized by immunohistochemical localization of serotonin combined with autoradiographic imaging of serotonin-uptake sites. |
1987-07-17 |
2023-08-11 |
rat |
| E H Lee, F B Wang, Y P Tang, M A Geye. Gabaergic interneurons in the dorsal raphe mediate the effects of apomorphine on serotonergic system. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:2438015. |
apomorphine (apo) has been shown to elevate the concentrations of serotonin (5-ht) and its major metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the mesostriatal but not the mesolimbic serotonergic systems. |
1987-07-16 |
2023-08-11 |
Not clear |
| I Hilakivi, T Kovala, A Leppävuori, A Shvalof. Effects of serotonin and noradrenaline uptake blockers on wakefulness and sleep in cats. Pharmacology & toxicology. vol 60. issue 3. 1987-07-16. PMID:3473457. |
the aim of the study was to examine the role of serotonergic (5-ht) and noradrenergic mechanisms in the regulation of wakefulness and sleep. |
1987-07-16 |
2023-08-11 |
Not clear |
| V M Altan, N Yildizoğlu, Y Oztür. Decreased gastro-intestinal responses to certain agonists in streptozotocin- and alloxan-diabetic rats in vitro. Pharmacology. vol 34. issue 2-3. 1987-07-08. PMID:3035586. |
nevertheless, the experiments performed on the rat duodenum and gastric fundus strips with salbutamol and serotonin showed that the beta-adrenergic and serotonergic receptor activities of the gastro-intestinal tract decreased significantly in alloxan- and streptozotocin-induced diabetes. |
1987-07-08 |
2023-08-11 |
rat |
| H Francès, R Raisman, P Simon, I Struc. Lesions of the serotonergic system impair the facilitation of but not the tolerance to the effects of chronic clenbuterol administration. Psychopharmacology. vol 91. issue 4. 1987-06-30. PMID:2438713. |
to investigate the function of serotonin in tolerance and facilitation, lesions of the serotonergic system were performed by intracerebroventricular administration of the neurotoxin 5,7 dihydroxytryptamine (5,7-dht). |
1987-06-30 |
2023-08-11 |
mouse |
| M N Parisi, M L Vitale, M J Villar, F E Estivariz, S R Chiocchio, J H Tramezzan. Serotonergic terminals in the anterior hypothalamic nucleus involved in the prolactin release during suckling. Endocrinology. vol 120. issue 6. 1987-06-25. PMID:2436899. |
in order to investigate causal effect between the altered 5-ht neuronal activity in the rnha and the suckling-induced prl release, serotonergic neurotoxin was bilaterally injected in the rnha on day 1 of lactation. |
1987-06-25 |
2023-08-11 |
rat |
| S J Offord, R O Warwic. Differential effects of nialamide and clomipramine on serotonin efflux and autoreceptors. Pharmacology, biochemistry, and behavior. vol 26. issue 3. 1987-06-17. PMID:2437597. |
the 5-ht motor syndrome was used as an index of in vivo serotonergic function. |
1987-06-17 |
2023-08-11 |
rat |