| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A D Levy, P A Rittenhouse, Q Li, J E Kerr, T M Cabrera, G Battaglia, L D Van de Ka. Cocaine-induced suppression of renin secretion is partially mediated by serotonergic mechanisms. Pharmacology, biochemistry, and behavior. vol 42. issue 3. 1992-11-18. PMID:1409781. |
to determine whether serotonergic neurons mediate this effect, male sprague-dawley rats received the serotonin (5-ht) neurotoxin 5,7-dihydroxytryptamine (75 micrograms/side, icv) 2 weeks prior to cocaine injections (3.75-15 mg/kg, ip). |
1992-11-18 |
2023-08-11 |
rat |
| B Poeschla, J Gibbs, K J Simansky, G P Smit. The 5-HT1A agonist 8-OH-DPAT attenuates the satiating action of cholecystokinin. Pharmacology, biochemistry, and behavior. vol 42. issue 3. 1992-11-18. PMID:1409788. |
to investigate the dependence of the satiating action of cholecystokinin (cck) on serotonergic action at central 5-ht receptors, we examined the effect of systemic pretreatment with 8-oh-dpat (a 5-ht1a agonist that decreases central 5-ht synthesis and release via an action at somatodendritic autoreceptors in the brainstem raphe) on the suppression of food intake induced by systemic administration of cholecystokinin octapeptide (ckk-8). |
1992-11-18 |
2023-08-11 |
Not clear |
| J W Boja, W M Mitchell, A Patel, T A Kopajtic, F I Carroll, A H Lewin, P Abraham, M J Kuha. High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain. Synapse (New York, N.Y.). vol 12. issue 1. 1992-11-12. PMID:1411961. |
conversely, serotonin uptake inhibitors blocked the binding of [125i]rti-55 in brain areas rich in serotonergic neurons. |
1992-11-12 |
2023-08-11 |
rat |
| M Yoshioka, M Matsumoto, H Togashi, C B Smith, H Sait. Effect of clonidine on the release of serotonin from the rat hippocampus as measured by microdialysis. Neuroscience letters. vol 139. issue 1. 1992-11-06. PMID:1383883. |
these results suggest that the inhibitory effect of clonidine on serotonin release from the hippocampus might reflect the activation of alpha 2-adrenoceptors which are localized on the serotonergic nerve terminals. |
1992-11-06 |
2023-08-11 |
rat |
| J P Tassi. NE/DA interactions in prefrontal cortex and their possible roles as neuromodulators in schizophrenia. Journal of neural transmission. Supplementum. vol 36. 1992-10-22. PMID:1356142. |
the monoaminergic innervation of the rat prefrontal cortex arises from well-defined mesencephalic nuclei, with noradrenergic (ne) neurons located in the locus coeruleus, dopaminergic (da) neurons located in the ventral tegmental area, and serotonergic (5-ht) neurons originating in the raphe nuclei. |
1992-10-22 |
2023-08-11 |
rat |
| V Conde López, M Martínez Roi. [Azaspirodecanodiones in clinical psychiatry]. Actas luso-espanolas de neurologia, psiquiatria y ciencias afines. vol 20. issue 4. 1992-10-22. PMID:1356293. |
buspirone--the only one available--is a novel nonbenzodiazepine anxiolytic that shows affinity for the serotonin 1a receptor subtype, acting as a partial agonist in the serotonergic system. |
1992-10-22 |
2023-08-11 |
Not clear |
| E A Engleman, J M Murphy, F C Zhou, J N Hingtge. Response suppression induced with selective 5-HT agonists can be differentially blocked with LY53857 in an animal model of depression. Neurochemical research. vol 17. issue 5. 1992-10-22. PMID:1388251. |
to further investigate the serotonergic mechanisms involved in this effect, we decided to test the capacity of ly53857 to block response suppression induced with two selective 5-ht agonists. |
1992-10-22 |
2023-08-11 |
rat |
| T Hisamitsu, M Fujishita, S Asamoto, A Nakamura, C Takeshig. Serotonergic neurons in the brainstem modulate animal hypnosis. Brain research bulletin. vol 29. issue 2. 1992-10-22. PMID:1525669. |
the involvement of serotonergic neurons in this area of animal hypnosis was investigated by microinjection of serotonin into these regions. |
1992-10-22 |
2023-08-11 |
rabbit |
| R W Fulle. Effects of p-chloroamphetamine on brain serotonin neurons. Neurochemical research. vol 17. issue 5. 1992-10-22. PMID:1528354. |
pca can also be used as a neurotoxic agent to deplete brain serotonin in functional studies, apparently by destroying some serotonergic nerve terminals. |
1992-10-22 |
2023-08-11 |
Not clear |
| S D Mendelso. A review and reevaluation of the role of serotonin in the modulation of lordosis behavior in the female rat. Neuroscience and biobehavioral reviews. vol 16. issue 3. 1992-10-22. PMID:1528523. |
in order to shed light on the physiological significance of effects of serotonergic drugs on lordosis, there is also a review of what is known of changes in levels of serotonergic activity and densities of 5-ht receptors in the female rat brain that take place through the estrous cycle and in response to administration of behaviorally effective doses of gonadal steroids. |
1992-10-22 |
2023-08-11 |
rat |
| S D Mendelso. A review and reevaluation of the role of serotonin in the modulation of lordosis behavior in the female rat. Neuroscience and biobehavioral reviews. vol 16. issue 3. 1992-10-22. PMID:1528523. |
because of a lack of consistent or compelling evidence of effects of ovarian hormones on serotonergic activity or 5-ht receptors in critical areas of the brain, it is stated that there is at present no basis to conclude that the effects of pharmacological manipulations of serotonergic activity on lordosis reflect an important, physiological role of 5-ht in the modulation of lordosis behavior in the female rat. |
1992-10-22 |
2023-08-11 |
rat |
| L Staner, C Kempenaers, M P Simonnet, L Fransolet, J Mendlewic. 5-HT2 receptor antagonism and slow-wave sleep in major depression. Acta psychiatrica Scandinavica. vol 86. issue 2. 1992-10-20. PMID:1529736. |
specific sleep disturbances such as reduced slow-wave sleep (sws) and decreased serotonergic (5-ht) activity have been observed in depressive disorders. |
1992-10-20 |
2023-08-11 |
human |
| L C Reis, M J Ramalho, J Antunes-Rodrigue. Central serotonergic modulation of drinking behavior induced by water deprivation: effect of a serotonergic agonist (MK-212) administered intracerebroventricularly. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 23. issue 12. 1992-10-07. PMID:2136566. |
the present study was carried out to evaluate the participation of the serotonergic system (5-ht) in the modulation of the drinking response induced by water deprivation. |
1992-10-07 |
2023-08-11 |
rat |
| L C Reis, M J Ramalho, J Antunes-Rodrigue. Central serotonergic modulation of drinking behavior induced by angiotensin II and carbachol in normally hydrated rats: effect of intracerebroventricular injection of MK-212. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 23. issue 12. 1992-10-07. PMID:2136567. |
the objective of the present study was to evaluate the role of the central serotonergic (5-ht) system in the modulation of drinking behavior induced by angiotensin ii (ang ii) and carbachol. |
1992-10-07 |
2023-08-11 |
rat |
| D Metodiewa, H B Dunfor. Peroxidase-promoted oxidation and peroxidation of the serotonergic neurotoxin 5,7-dihydroxytryptamine. A new pathway for its metabolic degradation. Molecular and cellular biochemistry. vol 112. issue 1. 1992-10-01. PMID:1513333. |
the one-electron peroxidatic oxidation of this serotonergic neurotoxin, responsible for the selective degeneration of central (5-hydroxytryptamine) neurons, is a fast process requiring measurement on the ms time scale. |
1992-10-01 |
2023-08-11 |
Not clear |
| B Olivier, J Mo. Rodent models of aggressive behavior and serotonergic drugs. Progress in neuro-psychopharmacology & biological psychiatry. vol 16. issue 6. 1992-09-30. PMID:1513929. |
by and large, male and female rats react similarly to treatment with serotonergic drugs stressing the consistent role of 5-ht in different forms of aggression. |
1992-09-30 |
2023-08-11 |
rat |
| L Hernádi, L Hiripi, A Vehovszky, G Kemenes, K Rózs. Ultrastructural, biochemical and electrophysiological changes induced by 5,6-dihydroxytryptamine in the CNS of the snail Helix pomatia L. Brain research. vol 578. issue 1-2. 1992-09-25. PMID:1324760. |
neurotoxin-induced structural alterations were found in neuronal processes and cell bodies of the serotonergic metacerebral giant cells injected intracellularly with horseradish peroxidase and in serotonin immunoreactive axons. |
1992-09-25 |
2023-08-11 |
Not clear |
| D L Sparks, J C Hunsaker, J T Slevin, S T DeKosky, R J Kryscio, W R Markesber. Monoaminergic and cholinergic synaptic markers in the nucleus basalis of Meynert (nbM): normal age-related changes and the effect of heart disease and Alzheimer's disease. Annals of neurology. vol 31. issue 6. 1992-09-25. PMID:1355334. |
the reduction of 5-ht and 5-hiaa content and [3h]spiperone binding in individuals with ad of all ages suggests a loss of functional serotonergic innervation of the nbm. |
1992-09-25 |
2023-08-11 |
human |
| U V Berger, R Grzanna, M E Mollive. The neurotoxic effects of p-chloroamphetamine in rat brain are blocked by prior depletion of serotonin. Brain research. vol 578. issue 1-2. 1992-09-25. PMID:1511276. |
systemic administration of p-chloroamphetamine (pca) causes degeneration of serotonergic (5-ht) axons, but recent data indicate that this drug itself is not neurotoxic when applied directly to 5-ht axons. |
1992-09-25 |
2023-08-11 |
rat |
| A D Levy, P A Rittenhouse, Q Li, A M Bonadonna, M C Alvarez Sanz, J E Kerr, C L Bethea, L D van de Ka. Repeated injections of cocaine inhibit the serotonergic regulation of prolactin and renin secretion in rats. Brain research. vol 580. issue 1-2. 1992-09-23. PMID:1504817. |
alterations in serotonergic function following repeated cocaine injections were examined using neuroendocrine responses to a serotonin (5-ht) releaser and 5-ht agonists. |
1992-09-23 |
2023-08-11 |
rat |