| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Bell, X N Zhang, P M Whitaker-Azmiti. 5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents. Brain research. vol 571. issue 2. 1992-07-24. PMID:1535269. |
previously, we have found that the regulation of development of ascending serotonergic neurons is through the balance of two serotonin receptors. |
1992-07-24 |
2023-08-11 |
rat |
| J Bell, X N Zhang, P M Whitaker-Azmiti. 5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents. Brain research. vol 571. issue 2. 1992-07-24. PMID:1535269. |
our results show that agents stimulating the 5-ht1a receptor (8-oh-dpat) or the 5-ht1b receptor (tfmpp) or substances which release serotonin (fenfluramine) had no effect on the development of spinal serotonergic pathways. |
1992-07-24 |
2023-08-11 |
rat |
| J H Haring, L Meyerson, T L Hoffma. Effects of para-chloroamphetamine upon the serotonergic innervation of the rat hippocampus. Brain research. vol 577. issue 2. 1992-07-23. PMID:1606500. |
the ability of hippocampal serotonergic (5-ht) axons to proliferate in response to damage by para-chloroamphetamine (pca) was examined in this study. |
1992-07-23 |
2023-08-11 |
rat |
| A Weizman, A Mandel, Y Barber, R Weitz, A Cohen, R Mester, M Rehav. Decreased platelet imipramine binding in Tourette syndrome children with obsessive-compulsive disorder. Biological psychiatry. vol 31. issue 7. 1992-07-14. PMID:1318082. |
the decreased density of the platelet serotonin "transporter" might implicate the involvement of the serotonergic system in the pathophysiology of ocd in ts patients, but not in ts per se. |
1992-07-14 |
2023-08-11 |
human |
| D Marazziti, E Hollander, P Lensi, S Ravagli, G B Cassan. Peripheral markers of serotonin and dopamine function in obsessive-compulsive disorder. Psychiatry research. vol 42. issue 1. 1992-07-13. PMID:1603880. |
in an attempt to clarify the possible role of a serotonergic and dopaminergic dysfunction in obsessive-compulsive disorder (ocd), we measured platelet 3h-imipramine (3h-imi) binding, serotonin uptake, and platelet sulfotransferase activity in 17 drug-free ocd patients and an equal number of healthy controls. |
1992-07-13 |
2023-08-11 |
Not clear |
| D Marazziti, E Hollander, P Lensi, S Ravagli, G B Cassan. Peripheral markers of serotonin and dopamine function in obsessive-compulsive disorder. Psychiatry research. vol 42. issue 1. 1992-07-13. PMID:1603880. |
serotonin uptake and 3h-imi binding sites in platelets have been shown to constitute peripheral markers of those present in presynaptic serotonergic neurons. |
1992-07-13 |
2023-08-11 |
Not clear |
| E H Lee, W R Lin, H Y Chen, W H Shiu, K C Lian. Fluoxetine and 8-OH-DPAT in the lateral septum enhances and impairs retention of an inhibitory avoidance response in rats. Physiology & behavior. vol 51. issue 4. 1992-07-01. PMID:1534416. |
immediately after training, the septal serotonergic function was manipulated by pharmacological agents selectively blocking 5ht reuptake (fluoxetine and zimelidine), antagonizing 5ht2 receptors (ketanserin and ritanserin), or activating 5ht1a receptors, respectively. |
1992-07-01 |
2023-08-11 |
rat |
| M P Johnson, X M Huang, D E Nichol. Serotonin neurotoxicity in rats after combined treatment with a dopaminergic agent followed by a nonneurotoxic 3,4-methylenedioxymethamphetamine (MDMA) analogue. Pharmacology, biochemistry, and behavior. vol 40. issue 4. 1992-06-30. PMID:1726189. |
there is increasing evidence linking dopamine (da) to the long-term serotonergic (5-ht) neurotoxic effects of certain substituted amphetamines such as 3,4-methylenedioxymethamphetamine (mdma). |
1992-06-30 |
2023-08-11 |
rat |
| R A Glennon, M Duka. Serotonin receptors and their ligands: a lack of selective agents. Pharmacology, biochemistry, and behavior. vol 40. issue 4. 1992-06-30. PMID:1816555. |
there is presently available an abundance of serotonergic agents; however, these agents are only semiselective, and none can be considered truly selective for a particular population of 5-ht receptors. |
1992-06-30 |
2023-08-11 |
Not clear |
| Q P Ma, G F Yin, M K Ai, J S Ha. Serotonergic projections from the nucleus raphe dorsalis to the amygdala in the rat. Neuroscience letters. vol 134. issue 1. 1992-06-24. PMID:1815148. |
in the present study, horseradish peroxidase (hrp) retrograde tracing was used in combination with serotonin (5-ht) immunocytochemical staining in an attempt to search for serotonergic projections from the nrd to the amygdala. |
1992-06-24 |
2023-08-11 |
rat |
| L P Morin, J Blanchar. Depletion of brain serotonin by 5,7-DHT modifies hamster circadian rhythm response to light. Brain research. vol 566. issue 1-2. 1992-06-23. PMID:1814534. |
serotonin immunohistochemistry showed an approximate 90% loss of cells from the dorsal raphe nucleus and decreased density of the serotonergic terminal field in the scn and igl. |
1992-06-23 |
2023-08-11 |
Not clear |
| B R Noga, H Bras, E Jankowsk. Transmission from group II muscle afferents is depressed by stimulation of locus coeruleus/subcoeruleus, Kölliker-Fuse and raphe nuclei in the cat. Experimental brain research. vol 88. issue 3. 1992-06-19. PMID:1316845. |
since field potentials at these locations are preferentially depressed by ionophoretic application of serotonin and noradrenaline (bras et al., 1990), and since the locus coeruleus/subcoeruleus, kölliker-fuse and raphe nuclei are interconnected, the study leads to the conclusion that both noradrenergic and serotonergic descending pathways can be activated by stimuli applied within either of them. |
1992-06-19 |
2023-08-11 |
cat |
| J Liu, J M Laude. Serotonin promotes region-specific glial influences on cultured serotonin and dopamine neurons. Glia. vol 5. issue 4. 1992-06-19. PMID:1350272. |
to test the hypothesis that glia mediate interactions between embryonic serotonergic (5-ht) neurons and dopamine neurons, we studied the effects of 5-ht in co-cultures of e14 raphe neurons of mesencephalic dopamine neurons and radial glia/astrocytes derived from the same (homotypic) or opposite (heterotypic) brain region using a dose (10(-5) m) that would produce 5-ht uptake into glial cells as well as activate 5-ht receptors. |
1992-06-19 |
2023-08-11 |
Not clear |
| B T Butler, G Silvey, D M Houston, D R Borcherding, V L Vaughn, A T McPhail, D M Radzik, H Wynberg, W ten Hoeve, E van Echte. The resolution, isolation, and pharmacological characterization of the enantiomers of a benzamide containing a chiral sulfoxide. Chirality. vol 4. issue 3. 1992-06-19. PMID:1586586. |
rac-ml-1035 (mdl 201,035: 4-amino-5-chloro-2-[2-(methylsulfinyl)ethoxy]-n-[2-(diethylamino)ethyl] benzamide hydrochloride) is a racemic gastroprokinetic with serotonergic (5-hydroxytryptamine, 5-ht) activity and a novel chiral sulfoxide substituent. |
1992-06-19 |
2023-08-11 |
rat |
| C M Chaturvedi, A B Sing. Suppression of annual testicular development in Indian Palm squirrel, Funambulus pennanti by 8 hr temporal relationship of serotonin and dopamine precursor drugs. Journal of neural transmission. General section. vol 88. issue 1. 1992-06-10. PMID:1575953. |
results indicate that induced suppression of gonadal function in a fashion similar to seasonal regression leading to non-breeding condition is the consequence of specific phase relationship (8 hr) between serotonergic and dopaminergic activities and not due to serotonin or dopamine alone. |
1992-06-10 |
2023-08-11 |
Not clear |
| P Ekström, T Ostholm, S O Ebbesso. A morphometric study of age-related changes in serotonin-immunoreactive cell groups in the brain of the coho salmon, Oncorhynchus kisutch Walbaum. Experimental neurology. vol 116. issue 2. 1992-06-10. PMID:1577128. |
these increases may be due to reorganization of the central serotonergic system, changes in serotonin turnover, or both. |
1992-06-10 |
2023-08-11 |
Not clear |
| S Winberg, G E Nilsson, K H Olsé. Changes in brain serotonergic activity during hierarchic behavior in Arctic charr (Salvelinus alpinus L.) are socially induced. Journal of comparative physiology. A, Sensory, neural, and behavioral physiology. vol 170. issue 1. 1992-05-29. PMID:1374127. |
further, we found that previous subordinate experience inhibited aggressive behavior, an effect which, in the light of available information on stress and 5-ht, could be related to the increase in brain serotonergic activity. |
1992-05-29 |
2023-08-11 |
Not clear |
| R Tao, S Hjort. Alpha 2-adrenoceptor modulation of rat ventral hippocampal 5-hydroxytryptamine release in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 345. issue 2. 1992-05-22. PMID:1349158. |
the putative existence of a functional alpha 2-adrenoceptor-mediated modulation of 5-ht release in vivo from serotonergic neuronal terminals in the ventral hippocampus was investigated using intracerebral microdialysis in chloral hydrate-anaesthetised rats. |
1992-05-22 |
2023-08-11 |
rat |
| R Tao, S Hjort. Alpha 2-adrenoceptor modulation of rat ventral hippocampal 5-hydroxytryptamine release in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 345. issue 2. 1992-05-22. PMID:1349158. |
the results demonstrate that the release of 5-ht from serotonergic nerve terminals in rat ventral hippocampus in vivo is modulated by alpha 2-adrenoceptors, probably both by heteroreceptors on the axon terminals of the serotonergic neurones and by other alpha 2-adrenoceptor sites situated pre- and/or postsynaptic to the noradrenergic terminals. |
1992-05-22 |
2023-08-11 |
rat |
| P I Markowit. Effect of fluoxetine on self-injurious behavior in the developmentally disabled: a preliminary study. Journal of clinical psychopharmacology. vol 12. issue 1. 1992-04-30. PMID:1552036. |
based on the assumption that this maladaptive behavior may be related to central nervous system serotonergic imbalance or dysfunction, an open trial with a serotonin uptake inhibitor was conducted. |
1992-04-30 |
2023-08-11 |
Not clear |