| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jasminka Stefulj, Andreas Büttner, Milovan Kubat, Peter Zill, Melita Balija, Wolfgang Eisenmenger, Brigitta Bondy, Branimir Jerne. 5HT-2C receptor polymorphism in suicide victims. Association studies in German and Slavic populations. European archives of psychiatry and clinical neuroscience. vol 254. issue 4. 2004-10-04. PMID:15309390. |
based on the association of suicide and serotonergic dysfunction, it was proposed that genetic mechanisms affecting suicidal behaviour could be related to the alterations of the genes encoding the elements of 5ht synapse. |
2004-10-04 |
2023-08-12 |
Not clear |
| René Hummerich, Gerald Reischl, Walter Ehrlichmann, Hans-Jürgen Machulla, Andreas Heinz, Patrick Schlos. DASB -in vitro binding characteristics on human recombinant monoamine transporters with regard to its potential as positron emission tomography (PET) tracer. Journal of neurochemistry. vol 90. issue 5. 2004-09-30. PMID:15312176. |
the efficiency of serotonergic signal transduction is controlled by the density of serotonegic synapses and by the activity of the serotonin transporter (sert), which selectively clears the synaptic cleft of the neurotransmitter. |
2004-09-30 |
2023-08-12 |
human |
| Srividya Subramanian, Regis R Vollme. Fenfluramine-induced hypothermia is associated with cutaneous dilation in conscious rats. Pharmacology, biochemistry, and behavior. vol 77. issue 2. 2004-09-28. PMID:14751464. |
moreover, the effects of fenfluramine on t(tail) and t(core) depended on the uptake of fenfluramine into serotonergic neurons because these effects were markedly attenuated by pretreatment with the selective serotonin re-uptake inhibitor, fluoxetine. |
2004-09-28 |
2023-08-12 |
rat |
| C P Müller, H Thönnessen, M A De Souza Silva, H Fink, B Bert, R J Carey, J P Husto. Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223299. |
the nucleus accumbens (nac) is an important structure for cocaine-induced hyperactivity and receives a dense serotonergic (5-ht) innervation. |
2004-09-28 |
2023-08-12 |
rat |
| Luiz F Takase, Maria Ines Nogueira, Michael Baratta, Sondra T Bland, Linda R Watkins, Steven F Maier, Casimir A Fornal, Barry L Jacob. Inescapable shock activates serotonergic neurons in all raphe nuclei of rat. Behavioural brain research. vol 153. issue 1. 2004-09-27. PMID:15219724. |
using immunohistochemical double labeling for c-fos activation and serotonin, we examined the effects of delivering 100 inescapable tailshocks to rats on serotonergic neuronal activation throughout the brainstem raphe system. |
2004-09-27 |
2023-08-12 |
human |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
furthermore, in a different model of serotonergic and noradrenergic degeneration, bdnf protein levels were similarly increased in response to depletions in hippocampal serotonin and norepinephrine caused by the chemical neurotoxin 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-nh2-mptp). |
2004-09-24 |
2023-08-12 |
mouse |
| Andrew H Kemp, Marcus A Gray, Richard B Silberstein, Stuart M Armstrong, Pradeep J Natha. Augmentation of serotonin enhances pleasant and suppresses unpleasant cortical electrophysiological responses to visual emotional stimuli in humans. NeuroImage. vol 22. issue 3. 2004-09-16. PMID:15219580. |
the serotonergic system is one of the major systems targeted in the pharmacological treatment of a wide range of mood disorders including depression; however, little is known about the neurophysiological mechanisms underlying the effects of serotonin (5-ht) on affective phenomena including emotional behaviours, mood and emotional processing. |
2004-09-16 |
2023-08-12 |
human |
| Jean-Claude Béïque, Brian Campbell, Paul Perring, Mark W Hamblin, Paul Walker, Ljiljana Mladenovic, Rodrigo Andrad. Serotonergic regulation of membrane potential in developing rat prefrontal cortex: coordinated expression of 5-hydroxytryptamine (5-HT)1A, 5-HT2A, and 5-HT7 receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 20. 2004-09-10. PMID:15152041. |
serotonergic regulation of membrane potential in developing rat prefrontal cortex: coordinated expression of 5-hydroxytryptamine (5-ht)1a, 5-ht2a, and 5-ht7 receptors. |
2004-09-10 |
2023-08-12 |
rat |
| Jean-Claude Béïque, Brian Campbell, Paul Perring, Mark W Hamblin, Paul Walker, Ljiljana Mladenovic, Rodrigo Andrad. Serotonergic regulation of membrane potential in developing rat prefrontal cortex: coordinated expression of 5-hydroxytryptamine (5-HT)1A, 5-HT2A, and 5-HT7 receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 20. 2004-09-10. PMID:15152041. |
the developing prefrontal cortex receives a dense serotonergic innervation, yet little is known about the actions of serotonin [5-hydroxytryptamine (5-ht)] in this region during development. |
2004-09-10 |
2023-08-12 |
rat |
| Xiaohua Li, Wawa Zhu, Myoung-Sun Roh, Ari B Friedman, Kelley Rosborough, Richard S Jop. In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 8. 2004-09-08. PMID:15039769. |
this indicates that serotonergic regulation of the phosphorylation of gsk3beta is achieved by a balance between the opposing actions of these 5ht receptor subtypes. |
2004-09-08 |
2023-08-12 |
mouse |
| Shaun Jordan, Vuk Koprivica, Robert Dunn, Katsura Tottori, Tetsuro Kikuchi, C Anthony Alta. In vivo effects of aripiprazole on cortical and striatal dopaminergic and serotonergic function. European journal of pharmacology. vol 483. issue 1. 2004-09-07. PMID:14709325. |
together, these data provide in vivo evidence of aripiprazole-induced changes in forebrain dopaminergic and serotonergic function that may reflect its partial agonist activity at presynaptic dopamine d(2) and 5-ht(1a) receptors and antagonist activity at 5-ht(2a) receptors. |
2004-09-07 |
2023-08-12 |
rat |
| Lori L Davis, Michele E Jewell, Sandra Ambrose, Jason Farley, Brett English, Al Bartolucci, Frederick Pett. A placebo-controlled study of nefazodone for the treatment of chronic posttraumatic stress disorder: a preliminary study. Journal of clinical psychopharmacology. vol 24. issue 3. 2004-09-07. PMID:15118483. |
nefazodone is a unique serotonergic antidepressant that acts as both a presynaptic serotonin reuptake inhibitor and a postsynaptic 5-hydroxytryptamine 2a receptor antagonist. |
2004-09-07 |
2023-08-12 |
Not clear |
| Wim J Riedel, Sjacko Sobczak, Jeroen A J Schmit. Tryptophan modulation and cognition. Advances in experimental medicine and biology. vol 527. 2004-09-02. PMID:15206734. |
the interest in the function of the serotonergic system in relation to cognition stems from three sources: (1) the association of depression, cognitive dysfunction and 5-ht dysregulation; (2) the association of drug-induced 5-ht dysregulation and cognitive dysfunction; and (3) the association of cognitive performance and serotonergic function per se. |
2004-09-02 |
2023-08-12 |
human |
| Toshimi Owashi, Shuji Iritani, Kazuhiro Niizato, Kenji Ikeda, Kunitoshi Kamijim. The distribution of serotonin transporter immunoreactivity in hippocampal formation in monkeys and rats. Brain research. vol 1010. issue 1-2. 2004-09-01. PMID:15126130. |
to elucidate the anatomical distribution of the serotonergic neurotransmitter system, we identified serotonin transporter (5-htt) in the hippocampus of rats and monkeys by immunohistochemistry. |
2004-09-01 |
2023-08-12 |
rat |
| P C Hubbard, R J Balment, C R McCroha. Inhibitory effect of 5-hydroxytryptamine receptor activation on caudal neurosecretory cells of the flounder, Platichthys flesus. Journal of neuroendocrinology. vol 9. issue 7. 2004-08-25. PMID:15305575. |
in contrast to the findings in type 1 cells, cells identified as 'type 2' (putative urotensin ii-secreting) did not respond to either 5-ht or 5-ct, suggesting that the serotonergic input into the cnss plays no role in the modulation of activity of this sub-population of neuroendocrine cells. |
2004-08-25 |
2023-08-12 |
Not clear |
| Laszlo G Harsing, Ibolya Prauda, Jozsef Barkoczy, Peter Matyus, Zsolt Jurany. A 5-HT7 heteroreceptor-mediated inhibition of [3H]serotonin release in raphe nuclei slices of the rat: evidence for a serotonergic-glutamatergic interaction. Neurochemical research. vol 29. issue 8. 2004-08-19. PMID:15260125. |
they also suggest that 5-ht7 receptors are probably not located on serotonergic neurons and thus may serve as heteroreceptors in regulation of 5-ht release in the raphe nuclei. |
2004-08-19 |
2023-08-12 |
rat |
| Philip L Johnson, Stafford L Lightman, Christopher A Lowr. A functional subset of serotonergic neurons in the rat ventrolateral periaqueductal gray implicated in the inhibition of sympathoexcitation and panic. Annals of the New York Academy of Sciences. vol 1018. 2004-08-18. PMID:15240352. |
the origin of endogenous 5-ht in the dlpag and rvlm seems to be a subpopulation of serotonergic neurons within the ventrolateral pag, a region implicated in "freezing" or "no go" behaviors. |
2004-08-18 |
2023-08-12 |
rat |
| Seiichiro Shimazu, Hiroko Tsunekawa, Fumio Yoneda, Hiroshi Katsuki, Akinori Akaike, Aaron Janowsk. Transporter-mediated actions of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane. European journal of pharmacology. vol 482. issue 1-3. 2004-08-16. PMID:14659999. |
r-(-)-1-(benzofuran-2-yl)-2-propylaminopentane [(-)-bpap] is a catecholaminergic and serotonergic activity enhancer that increases impulse-evoked catecholamine and serotonin release from nerve terminals, and is a candidate for symptomatic treatment of early parkinson's disease. |
2004-08-16 |
2023-08-12 |
human |
| Seiichiro Shimazu, Hiroko Tsunekawa, Fumio Yoneda, Hiroshi Katsuki, Akinori Akaike, Aaron Janowsk. Transporter-mediated actions of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane. European journal of pharmacology. vol 482. issue 1-3. 2004-08-16. PMID:14659999. |
we conclude that (-)-bpap is not only catecholaminergic and serotonergic activity enhancer, but also a norepinephrine and dopamine uptake inhibitor and a weak serotonin uptake inhibitor that does not possess a tyramine-like action on catecholamine release, and is an inhibitor of tyramine-induced release of norepinephrine. |
2004-08-16 |
2023-08-12 |
human |
| Motoko Honda, Mitsuo Tanabe, Hideki On. Serotonergic depression of spinal monosynaptic transmission is mediated by 5-HT1B receptors. European journal of pharmacology. vol 482. issue 1-3. 2004-08-16. PMID:14660017. |
these results suggest that serotonergic depression of monosynaptic reflex transmission is mediated by 5-ht(1b) receptors. |
2004-08-16 |
2023-08-12 |
rat |