| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eszter Kirilly, Eszter Molnar, Brigitta Balogh, Sandor Kantor, Stefan R Hansson, Miklos Palkovits, Gyorgy Bagd. Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days. The international journal of neuropsychopharmacology. vol 11. issue 6. 2008-12-18. PMID:18261250. |
since there is evidence that serotonin regulates sleep, we have compared serotonergic markers parallel with detailed analysis of sleep patterns at three time-points within 180 d after a single dose of 15 mg/kg mdma in male dark agouti rats. |
2008-12-18 |
2023-08-12 |
human |
| D G H Kro. [Sexsomnia during treatment with a selective serotonin reuptake inhibitor]. Tijdschrift voor psychiatrie. vol 50. issue 11. 2008-12-18. PMID:18991234. |
the temporal relationship between the use of this selective serotonin reuptake inhibitor and the occurrence of the parasomnia suggests a causal relationship, possibly related to increased serotonergic neurotransmission in the raphe nucleus. |
2008-12-18 |
2023-08-12 |
Not clear |
| Maartje M L de Win, Gerry Jager, Jan Booij, Liesbeth Reneman, Thelma Schilt, Cristina Lavini, Sílvia D Olabarriaga, Gerard J den Heeten, Wim van den Brin. Sustained effects of ecstasy on the human brain: a prospective neuroimaging study in novel users. Brain : a journal of neurology. vol 131. issue Pt 11. 2008-12-12. PMID:18842607. |
neuroimaging included [(123)i]beta-carbomethoxy-3beta-(4-iodophenyl)tropane (cit) spect to measure serotonin transporter densities as indicators of serotonergic function; (1)h-mr spectroscopy ((1)h-mrs) to measure brain metabolites as indicators of neuronal damage; diffusion tensor imaging (dti) to measure the apparent diffusion coefficient and fractional anisotropy (fa) of the diffusional motion of water molecules in the brain as indicators of axonal integrity; and perfusion weighted imaging (pwi) to measure regional relative cerebral blood volume (rrcbv) which indicates brain perfusion. |
2008-12-12 |
2023-08-12 |
human |
| Norikazu Ezaki, Kazuhiko Nakamura, Yoshimoto Sekine, Ismail Thanseem, Ayyappan Anitha, Yasuhide Iwata, Masayoshi Kawai, Kiyokazu Takebayashi, Katsuaki Suzuki, Nori Takei, Masaomi Iyo, Toshiya Inada, Nakao Iwata, Mutsuo Harano, Tokutaro Komiyama, Mitsuhiko Yamada, Ichiro Sora, Hiroshi Ujike, Norio Mor. Short allele of 5-HTTLPR as a risk factor for the development of psychosis in Japanese methamphetamine abusers. Annals of the New York Academy of Sciences. vol 1139. 2008-12-09. PMID:18991848. |
prolonged map use, combined with the high frequency of 5-httlpr s-alleles, may lead to reduced 5-htt levels and 5-ht(1a) receptor-binding potential in the brain, resulting in the dysfunction of the serotonergic system. |
2008-12-09 |
2023-08-12 |
Not clear |
| Benicio N Frey, Pedro Rosa-Neto, Stuart Lubarsky, Mirko Diksi. Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: a combined alpha-[11C]MT and [18F]MPPF positron emission tomography study. NeuroImage. vol 42. issue 2. 2008-12-08. PMID:18583156. |
while most of what is known about serotonin comes from studies in animals, much less empirical evidence exists about the serotonergic system in the living human brain. |
2008-12-08 |
2023-08-12 |
human |
| Sunil Kumar, Ronald Szymusiak, Tariq Bashir, Natalia Suntsova, Seema Rai, Dennis McGinty, Md Noor Ala. Inactivation of median preoptic nucleus causes c-Fos expression in hypocretin- and serotonin-containing neurons in anesthetized rat. Brain research. vol 1234. 2008-12-08. PMID:18722360. |
the hypocretinergic (hcrt) neurons of the perifornical-lateral hypothalamic area (pf-lha) and serotonergic (5-ht) neurons of the dorsal raphe nucleus (drn) are mostly active during waking and have been implicated in the regulation of arousal. |
2008-12-08 |
2023-08-12 |
rat |
| Christine H Huang, Susan L Santangel. Autism and serotonin transporter gene polymorphisms: a systematic review and meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18286633. |
the serotonin transporter gene (5-htt) plays a crucial role in serotonergic neurotransmission and has been found to be associated, with varying degrees of significance, with many diseases, including autism. |
2008-12-04 |
2023-08-12 |
Not clear |
| L J C A Smarius, G E Jacobs, D H M Hoeberechts-Lefrandt, M L de Kam, J P van der Post, R de Rijk, J van Pelt, R C Schoemaker, F G Zitman, J M A van Gerven, H J Gijsma. Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa. Journal of psychopharmacology (Oxford, England). vol 22. issue 4. 2008-12-03. PMID:18308795. |
5-hydroxytryptophan (5-htp) is a direct 5-hydroxytryptamine (5-ht) precursor used to assess central serotonergic function. |
2008-12-03 |
2023-08-12 |
human |
| Elodie Pradines, Damien Loubet, Benoît Schneider, Jean-Marie Launay, Odile Kellermann, Sophie Mouillet-Richar. CREB-dependent gene regulation by prion protein: impact on MMP-9 and beta-dystroglycan. Cellular signalling. vol 20. issue 11. 2008-12-03. PMID:18718863. |
by exploiting the properties of the 1c11 neuroectodermal cell line, able to convert into 1c11(5-ht) serotonergic or 1c11(ne) noradrenergic neuronal cells, we assigned a signaling function to prp(c). |
2008-12-03 |
2023-08-12 |
Not clear |
| Antón Barreiro-Iglesias, Verona Villar-Cerviño, Ramón Anadón, María Celina Rodici. Development and organization of the descending serotonergic brainstem-spinal projections in the sea lamprey. Journal of chemical neuroanatomy. vol 36. issue 2. 2008-12-01. PMID:18602462. |
the organization and development of the descending spinal projections from serotonergic rhombencephalic neurons in the larval sea lamprey were investigated by double labeling, tract-tracing methods and immunocytochemistry against serotonin. |
2008-12-01 |
2023-08-12 |
Not clear |
| Rocchina Colucci, Corrado Blandizzi, Massimo Bellini, Narcisa Ghisu, Marcello Tonini, Mario Del Tacc. The genetics of the serotonin transporter and irritable bowel syndrome. Trends in molecular medicine. vol 14. issue 7. 2008-11-26. PMID:18550438. |
abnormalities in serotonin reuptake can alter enteric serotonergic signalling, leading to sensory, motor and secretory gut dysfunctions, which contribute to the pathophysiology of irritable bowel syndrome (ibs). |
2008-11-26 |
2023-08-12 |
human |
| Y Dempsie, M R MacLea. Pulmonary hypertension: therapeutic targets within the serotonin system. British journal of pharmacology. vol 155. issue 4. 2008-11-25. PMID:18536742. |
these are indirect serotonergic agonists and serotonin transporter substrates. |
2008-11-25 |
2023-08-12 |
Not clear |
| Dan J Stein, Antti A Ahokas, Christian de Bodina. Efficacy of agomelatine in generalized anxiety disorder: a randomized, double-blind, placebo-controlled study. Journal of clinical psychopharmacology. vol 28. issue 5. 2008-11-24. PMID:18794654. |
agomelatine is a novel agent that acts on melatonergic (mt(1), mt(2)) receptors and serotonergic (5-ht(2c)) receptors. |
2008-11-24 |
2023-08-12 |
Not clear |
| G Troy Smith, Nicole Comb. Serotonergic activation of 5HT1A and 5HT2 receptors modulates sexually dimorphic communication signals in the weakly electric fish Apteronotus leptorhynchus. Hormones and behavior. vol 54. issue 1. 2008-11-18. PMID:18336816. |
5ht(1a) and 5ht(1b) receptors mediate many serotonergic effects on social behavior, but other receptors, including 5ht(2) receptors, may also contribute. |
2008-11-18 |
2023-08-12 |
Not clear |
| G Troy Smith, Nicole Comb. Serotonergic activation of 5HT1A and 5HT2 receptors modulates sexually dimorphic communication signals in the weakly electric fish Apteronotus leptorhynchus. Hormones and behavior. vol 54. issue 1. 2008-11-18. PMID:18336816. |
these results suggest that serotonergic inhibition of chirping may be mediated by 5ht(2) receptors, but that serotonergic activation of 5ht(1a) receptors specifically increases the production of high-frequency chirps. |
2008-11-18 |
2023-08-12 |
Not clear |
| Stephanie Collins Reed, Frances R Levin, Suzette M Evan. Changes in mood, cognitive performance and appetite in the late luteal and follicular phases of the menstrual cycle in women with and without PMDD (premenstrual dysphoric disorder). Hormones and behavior. vol 54. issue 1. 2008-11-18. PMID:18413151. |
an altered serotonergic system in women with pmdd may be the underlying mechanism for the observed symptoms; correspondingly, treatment with specific serotonin reuptake inhibitors (ssris) remains the preferred treatment at this time. |
2008-11-18 |
2023-08-12 |
human |
| Eveline Strackx, Daniël L A van den Hove, Hellen P Steinbusch, Jos Prickaerts, Johan S H Vles, Carlos E Blanco, Harry W M Steinbusch, A W Danilo Gavilane. Fetal asphyxia leads to a decrease in dorsal raphe serotonergic neurons. Developmental neuroscience. vol 30. issue 5. 2008-11-18. PMID:18784408. |
anxiety-related behavior was tested in an open field, and design-based stereology was used for counting serotonergic (5-hydroxytryptamine/serotonin, 5-ht) neurons in the dorsal raphe nucleus (drn). |
2008-11-18 |
2023-08-12 |
rat |
| Brian J Mickey, Francesca Ducci, Colin A Hodgkinson, Scott A Langenecker, David Goldman, Jon-Kar Zubiet. Monoamine oxidase A genotype predicts human serotonin 1A receptor availability in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 44. 2008-11-18. PMID:18971477. |
the serotonergic system, including the serotonin 1a (5-ht(1a)) receptor, has been implicated in the pathophysiology of a number of neuropsychiatric disorders. |
2008-11-18 |
2023-08-12 |
human |
| Shirley A Hesketh, Adrian K Brennan, David S Jessop, David P Fin. Effects of chronic treatment with citalopram on cannabinoid and opioid receptor-mediated G-protein coupling in discrete rat brain regions. Psychopharmacology. vol 198. issue 1. 2008-11-17. PMID:18084745. |
there is growing interest in investigating the mechanisms of action of selective serotonin reuptake inhibitors (ssris), beyond their association with the serotonergic system, due to their wide therapeutic potential for disorders including depression, pain and addiction. |
2008-11-17 |
2023-08-12 |
rat |
| Patrícia de Souza Villa, José Vanderlei Menani, Gabriela Maria Pavan de Arruda Camargo, Luiz Antônio de Arruda Camargo, Wilson Abrão Saa. Activation of the serotonergic 5-HT1A receptor in the paraventricular nucleus of the hypothalamus inhibits water intake and increases urinary excretion in water-deprived rats. Regulatory peptides. vol 150. issue 1-3. 2008-11-14. PMID:18556076. |
the aim of this study was to investigate the role of serotonergic 5-ht(1a) receptors in the lateral-medial posterior magnocellular region of the pvn in the water intake and diuresis induced by 24 h of water deprivation. |
2008-11-14 |
2023-08-12 |
rat |