| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew K Evans, Niels Reinders, Katie A Ashford, Isabel N Christie, Jonathan B Wakerley, Christopher A Lowr. Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex. European journal of pharmacology. vol 590. issue 1-3. 2008-10-14. PMID:18577382. |
however, serotonin synthesis and tonic autoregulation of serotonergic neuronal firing rates are impaired in in vitro preparations lacking tryptophan. |
2008-10-14 |
2023-08-12 |
rat |
| S Rojas Vega, T Abel, R Lindschulten, W Hollmann, W Bloch, H K Strüde. Impact of exercise on neuroplasticity-related proteins in spinal cord injured humans. Neuroscience. vol 153. issue 4. 2008-10-08. PMID:18440711. |
the augmented prl concentration suggests that a possible mechanism by which exercise promotes neuroplasticity might be the activation of neural serotonergic pathways as 5-ht is the main prl releasing factor. |
2008-10-08 |
2023-08-12 |
human |
| Renato Leonardo Freitas, Gabriel Shimizu Bassi, Ana Maria de Oliveira, Norberto Cysne Coimbr. Serotonergic neurotransmission in the dorsal raphe nucleus recruits in situ 5-HT(2A/2C) receptors to modulate the post-ictal antinociception. Experimental neurology. vol 213. issue 2. 2008-10-08. PMID:18671968. |
serotonergic neurotransmission in the dorsal raphe nucleus recruits in situ 5-ht(2a/2c) receptors to modulate the post-ictal antinociception. |
2008-10-08 |
2023-08-12 |
rat |
| Renato Leonardo Freitas, Gabriel Shimizu Bassi, Ana Maria de Oliveira, Norberto Cysne Coimbr. Serotonergic neurotransmission in the dorsal raphe nucleus recruits in situ 5-HT(2A/2C) receptors to modulate the post-ictal antinociception. Experimental neurology. vol 213. issue 2. 2008-10-08. PMID:18671968. |
ketanserin is an antagonist with large affinity for 5-ht(2a/2c) serotonergic receptors, which, in this case, caused a significant decrease in the tail-flick latencies in seizing animals, compared to controls after the first 20 min following tonic-clonic convulsive reactions. |
2008-10-08 |
2023-08-12 |
rat |
| Valentina Ruggieri, Giovanni Vitale, Luigi Alberto Pini, Maurizio Sandrin. Differential involvement of opioidergic and serotonergic systems in the antinociceptive activity of N-arachidonoyl-phenolamine (AM404) in the rat: comparison with paracetamol. Naunyn-Schmiedeberg's archives of pharmacology. vol 377. issue 3. 2008-09-30. PMID:18404260. |
am404 did not change serotonergic activity, while paracetamol decreased serotonin turnover. |
2008-09-30 |
2023-08-12 |
rat |
| Dallas R Donohoe, Thang Phan, Kathrine Weeks, Eric J Aamodt, Donard S Dwye. Antipsychotic drugs up-regulate tryptophan hydroxylase in ADF neurons of Caenorhabditis elegans: role of calcium-calmodulin-dependent protein kinase II and transient receptor potential vanilloid channel. Journal of neuroscience research. vol 86. issue 11. 2008-09-30. PMID:18438926. |
consistent with the increase in serotonin in the adf neurons induced by the drugs, drug withdrawal after 24-hr treatment was accompanied by a rebound in the number of turns/reversals, which demonstrates behavioral adaptation in serotonergic systems. |
2008-09-30 |
2023-08-12 |
caenorhabditis_elegans |
| Shu-chi Hsiung, Adrianne Tin, Hadassah Tamir, Thomas F Franke, Kuo-peing Li. Inhibition of 5-HT1A receptor-dependent cell survival by cAMP/protein kinase A: role of protein phosphatase 2A and Bax. Journal of neuroscience research. vol 86. issue 10. 2008-09-30. PMID:18459133. |
serotonergic 5-ht(1a) receptor signaling leading to nuclear factor-kappab (nf-kappab) activation appears to be critical for cell survival. |
2008-09-30 |
2023-08-12 |
Not clear |
| Małgorzata Lehner, Ewa Taracha, Danuta Turzyńska, Alicja Sobolewska, Adam Hamed, Paulina Kołomańska, Anna Skórzewska, Piotr Maciejak, Janusz Szyndler, Andrzej Bidziński, Adam Płaźni. The role of the dorsomedial part of the prefrontal cortex serotonergic innervation in rat responses to the aversively conditioned context: behavioral, biochemical and immunocytochemical studies. Behavioural brain research. vol 192. issue 2. 2008-09-30. PMID:18499280. |
local administration of serotonergic neurotoxin (5,7-dihydroxytryptamine) to the dorsomedial part of the prefrontal cortex caused a very strong, structure and neurotransmitter selective depletion of serotonin concentration. |
2008-09-30 |
2023-08-12 |
rat |
| Ismo Makkonen, Raili Riikonen, Hannu Kokki, Mauno M Airaksinen, Jyrki T Kuikk. Serotonin and dopamine transporter binding in children with autism determined by SPECT. Developmental medicine and child neurology. vol 50. issue 8. 2008-09-26. PMID:18754896. |
the low sert binding reported here and the low serotonin synthesis capacity shown elsewhere may indicate maturation of a lesser number of serotonergic nerve terminals in individuals with autism. |
2008-09-26 |
2023-08-12 |
Not clear |
| Shikha Snigdha, Joanna C Neil. Improvement of phencyclidine-induced social behaviour deficits in rats: involvement of 5-HT1A receptors. Behavioural brain research. vol 191. issue 1. 2008-09-24. PMID:18453008. |
these findings suggest that the beneficial effects of drugs such as aripiprazole and fluoxetine on pcp-induced social behaviour deficits, a potential model of negative symptoms of schizophrenia, may be a consequence of modifications of the serotonergic system, in particular through an interaction with 5-ht(1a) receptors. |
2008-09-24 |
2023-08-12 |
rat |
| Andréy Mazarati, Prabha Siddarth, Roger A Baldwin, Don Shin, Rochelle Caplan, Raman Sanka. Depression after status epilepticus: behavioural and biochemical deficits and effects of fluoxetine. Brain : a journal of neurology. vol 131. issue Pt 8. 2008-09-15. PMID:18559371. |
biochemical studies revealed compromised serotonergic transmission in the raphe-hippocampal serotonergic pathway: decrease of serotonin (5-ht) concentration and turnover in the hippocampus, measured by high performance liquid chromatography, and decrease of 5-ht release from the hippocampus in response to raphe stimulation, measured by fast cyclic voltammetry. |
2008-09-15 |
2023-08-12 |
rat |
| Mark S Yeoman, Bhavik A Patel, Martin Arundell, Kim Parker, Danny O'Har. Synapse-specific changes in serotonin signalling contribute to age-related changes in the feeding behaviour of the pond snail, Lymnaea. Journal of neurochemistry. vol 106. issue 4. 2008-09-12. PMID:18565208. |
analysis of the serotonergic cerebral giant cell (cgc) input to the protraction motor neurone (b1) demonstrated that fluoxetine (10-100 nm) increased the amplitude/duration of the evoked epsp in both young and middle aged but not in old neurones, suggesting an age-related attenuation of the serotonin transporter. |
2008-09-12 |
2023-08-12 |
Not clear |
| Malcolm K Horne, Joohyung Lee, Feng Chen, Katherine Lanning, Doris Tomas, Andrew J Lawrenc. Long-term administration of cocaine or serotonin reuptake inhibitors results in anatomical and neurochemical changes in noradrenergic, dopaminergic, and serotonin pathways. Journal of neurochemistry. vol 106. issue 4. 2008-09-12. PMID:18624911. |
the anatomical and neurochemical changes in serotonergic fibers following cocaine or ssri treatment may be explained by attenuated 5-ht(1a) autoreceptor function in the raphe. |
2008-09-12 |
2023-08-12 |
rat |
| Florian Gerstl, Christian Windischberger, Markus Mitterhauser, Wolfgang Wadsak, Alexander Holik, Kurt Kletter, Ewald Moser, Siegfried Kasper, Rupert Lanzenberge. Multimodal imaging of human early visual cortex by combining functional and molecular measurements with fMRI and PET. NeuroImage. vol 41. issue 2. 2008-09-09. PMID:18420427. |
here, we assessed the relationship between the distribution of the major inhibitory serotonergic neurotransmitter receptor, the 5-ht(1a) subtype, and the functional organization within early visual cortex defined by retinotopic mapping. |
2008-09-09 |
2023-08-12 |
human |
| Maria A Siracusa, Loredana Salerno, Maria N Modica, Valeria Pittalà, Giuseppe Romeo, Maria E Amato, Mateusz Nowak, Andrzej J Bojarski, Ilario Mereghetti, Alfredo Cagnotto, Tiziana Mennin. Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands. Journal of medicinal chemistry. vol 51. issue 15. 2008-09-08. PMID:18598015. |
they were tested in radioligand binding experiments to evaluate their affinity for 5-ht 1a and 5-ht 2a serotonergic, alpha 1 adrenergic, d1, and d2 dopaminergic receptors. |
2008-09-08 |
2023-08-12 |
Not clear |
| Pu-Yuan Chang, Chia-Hsin Chuang, Jin-Chung Chen, Che-Se Tun. Behavioral and biochemical effects of amperozide and serotonin agents on nigrostriatal and mesolimbic dopamine systems. The Chinese journal of physiology. vol 51. issue 2. 2008-09-08. PMID:18666714. |
the evidence that serotonergic system could modulate these two pathways suggests that serotonin (5-ht) and related agents may possess potential therapeutic values against certain mental or motor disorders caused by dopamine malfunction. |
2008-09-08 |
2023-08-12 |
rat |
| L Hernádi, L Hiripi, J Gyori, Henriette Szabó, Agnes Vehovszk. The terrestrial snail, Helix pomatia, adapts to environmental conditions by the modulation of central arousal. Acta biologica Hungarica. vol 59 Suppl. 2008-09-05. PMID:18652371. |
in isolated cns preparations from aestivated animals the highest firing activity and serotonin sensitivity of the serotonergic (rpas) heart modulator neurons are recorded during rainy weather and the lowest parameters are observed in dry conditions. |
2008-09-05 |
2023-08-12 |
Not clear |
| Hisayo Sadamoto, Z Serfozo, E It. Localization of serotonin transporter mRNA in the CNS of Lymnaea stagnalis. Acta biologica Hungarica. vol 59 Suppl. 2008-09-05. PMID:18652373. |
the serotonin transporter, sert, is reported as a key molecule that regulates serotonergic neurotransmission. |
2008-09-05 |
2023-08-12 |
Not clear |
| Bing Mo, Na Feng, Kenneth Renner, Gina Forste. Restraint stress increases serotonin release in the central nucleus of the amygdala via activation of corticotropin-releasing factor receptors. Brain research bulletin. vol 76. issue 5. 2008-09-04. PMID:18534257. |
decreases in serotonergic activity in the central nucleus of the amygdala reduce responses to stressors, suggesting an important role for serotonin in this region of the amygdala in stress reactivity. |
2008-09-04 |
2023-08-12 |
rat |
| Raymond A Lorenz, Amy M Vandenberg, Elizabeth A Canep. Serotonergic antidepressants and linezolid: a retrospective chart review and presentation of cases. International journal of psychiatry in medicine. vol 38. issue 1. 2008-09-03. PMID:18624020. |
to report the results from a retrospective chart review looking at the combination of linezolid and serotonergic antidepressants and to report two cases of serotonin syndrome which were identified at our hospital. |
2008-09-03 |
2023-08-12 |
Not clear |