| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pilar A Saiz, Maria P García-Portilla, Begoña Paredes, Celso Arango, Blanca Morales, Victoria Alvarez, Eliecer Coto, Maria-Teresa Bascaran, Manuel Bousoño, Julio Bobe. Association between the A-1438G polymorphism of the serotonin 2A receptor gene and nonimpulsive suicide attempts. Psychiatric genetics. vol 18. issue 5. 2008-11-14. PMID:18797395. |
to investigate the association between four serotonergic polymorphisms [a-1438g (rs6311) and t102c (rs6313) of the serotonin 2a receptor gene, and stin2 vntr and 5-httlpr of the slc6a4 gene] and suicidal behavior. |
2008-11-14 |
2023-08-12 |
Not clear |
| Lin Jia, Yuan-Yuan Shang, Yu-Yuan L. Effect of antidepressants on body weight, ethology and tumor growth of human pancreatic carcinoma xenografts in nude mice. World journal of gastroenterology. vol 14. issue 27. 2008-11-13. PMID:18666329. |
to investigate the effects of mirtazapine and fluoxetine, representatives of the noradrenergic and specific serotonergic antidepressant (nassa) and selective serotonin reuptake inhibitor (ssri) antidepressant respectively, on body weight, ingestive behavior, locomotor activity and tumor growth of human pancreatic carcinoma xenografts in nude mice. |
2008-11-13 |
2023-08-12 |
mouse |
| Lydia Günther, Sabine Liebscher, Monika Jähkel, Jochen Oehle. Effects of chronic citalopram treatment on 5-HT1A and 5-HT2A receptors in group- and isolation-housed mice. European journal of pharmacology. vol 593. issue 1-3. 2008-11-12. PMID:18657534. |
a 2-3 week delay in the onset of effects is caused by adaptive mechanisms, probably at the serotonergic (5-ht) receptor level. |
2008-11-12 |
2023-08-12 |
mouse |
| Gerardo Florez, Pilar Saiz, Paz Garcia-Portilla, Sandra Alvarez, Luis Nogueíras, Blanca Morales, Victoria Alvarez, Eliecer Coto, Julio Bobe. Association between the Stin2 VNTR polymorphism of the serotonin transporter gene and treatment outcome in alcohol-dependent patients. Alcohol and alcoholism (Oxford, Oxfordshire). vol 43. issue 5. 2008-11-07. PMID:18552399. |
the aim of this study was to investigate the potential association between functional polymorphisms of dopaminergic [dopamine receptor d2 (drd2), dopamine receptor d3 (drd3) and dopamine transporter (slc6a3)] and serotonergic [serotonin 2a receptor (htr2a) and serotonin transporter (slc6a4)] genes and treatment outcome in alcohol-dependent patients. |
2008-11-07 |
2023-08-12 |
Not clear |
| Megumi Higuchi, Yuichi Suzuki, Yumi Yatani, Yutaka Kitagawa, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kanek. Augmentation of serotonin release by sustained exposure to MDMA and methamphetamine in rat organotypic mesencephalic slice cultures containing raphe serotonergic neurons. Journal of neurochemistry. vol 106. issue 6. 2008-11-07. PMID:18662325. |
augmentation of serotonin release by sustained exposure to mdma and methamphetamine in rat organotypic mesencephalic slice cultures containing raphe serotonergic neurons. |
2008-11-07 |
2023-08-12 |
rat |
| Megumi Higuchi, Yuichi Suzuki, Yumi Yatani, Yutaka Kitagawa, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kanek. Augmentation of serotonin release by sustained exposure to MDMA and methamphetamine in rat organotypic mesencephalic slice cultures containing raphe serotonergic neurons. Journal of neurochemistry. vol 106. issue 6. 2008-11-07. PMID:18662325. |
sustained mdma exposure augmented mdma-induced serotonin release in a concentration-dependent manner, indicating serotonergic sensitization. |
2008-11-07 |
2023-08-12 |
rat |
| Kevin C F Fone, M Veronica Porkes. Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders. Neuroscience and biobehavioral reviews. vol 32. issue 6. 2008-11-05. PMID:18423591. |
these alterations are associated with hyperfunction of mesolimbic dopaminergic systems, enhanced presynaptic dopamine (da) and serotonergic (5-ht) function in the nucleus accumbens (nacc), hypofunction of mesocortical da and attenuated 5-ht function in the prefrontal cortex and hippocampus. |
2008-11-05 |
2023-08-12 |
rat |
| Neil Upton, Tsu Tshen Chuang, Ann J Hunter, David J Virle. 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 5. issue 3. 2008-11-05. PMID:18625457. |
because of the extensive serotonergic denervation that has been observed in the ad brain and the important role played by serotonin (5-ht) in both cognition and behavioral control, this neurotransmitter system has become a focus of concerted research efforts to identify new treatments for ad. |
2008-11-05 |
2023-08-12 |
Not clear |
| Lee A Dawson, Steve M Bromidg. 5-HT1 receptor augmentation strategies as enhanced efficacy: therapeutics for psychiatric disorders. Current topics in medicinal chemistry. vol 8. issue 12. 2008-10-27. PMID:18691129. |
since the initial observations linking 5-ht to psychiatric illness, evidence for a role of 5-ht and, in particular, a decreased brain serotonergic function in the pathology of a plethora of related disorders, has grown. |
2008-10-27 |
2023-08-12 |
Not clear |
| Lee A Dawson, Steve M Bromidg. 5-HT1 receptor augmentation strategies as enhanced efficacy: therapeutics for psychiatric disorders. Current topics in medicinal chemistry. vol 8. issue 12. 2008-10-27. PMID:18691129. |
thus enhanced serotonergic neurotransmission has become one of the unifying mechanisms of action of modern day antidepressants/anxiolytics such as monoamine oxidase inhibitors, tricyclic antidepressants, and serotonin reuptake inhibitors. |
2008-10-27 |
2023-08-12 |
Not clear |
| Lee A Dawson, Steve M Bromidg. 5-HT1 receptor augmentation strategies as enhanced efficacy: therapeutics for psychiatric disorders. Current topics in medicinal chemistry. vol 8. issue 12. 2008-10-27. PMID:18691129. |
the postulated reason for this is the need for temporal neuroplastic changes in the control of serotonergic neurotransmission, and more specifically changes in 5-ht(1) autoreceptor function. |
2008-10-27 |
2023-08-12 |
Not clear |
| Laura Saenz del Burgo, Roser Cortes, Guadalupe Mengod, Jon Zarate, Enrique Echevarria, Joan Salle. Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain. The Journal of comparative neurology. vol 510. issue 6. 2008-10-27. PMID:18698588. |
we also analyze the co-expression of girk subunits with the 5-ht(1a) receptor and cell markers of glutamatergic, gamma-aminobutyric acid (gaba)ergic, cholinergic, and serotonergic neurons in different brain areas by double-label in situ hybridization. |
2008-10-27 |
2023-08-12 |
human |
| Kentaro Murakami, Yoshihiro Miyake, Satoshi Sasaki, Keiko Tanaka, Tetsuji Yokoyama, Yukihiro Ohya, Wakaba Fukushima, Chikako Kiyohara, Yoshio Hirot. Dietary glycemic index and load and the risk of postpartum depression in Japan: the Osaka Maternal and Child Health Study. Journal of affective disorders. vol 110. issue 1-2. 2008-10-24. PMID:18192024. |
given suggestions that postpartum depression may be due to the sudden fall in insulin levels occurring after delivery via a decrease in serotonergic function, this condition might be alleviated by a high-glycemic index (gi) diet, which would stimulate the secretion of insulin and thereby facilitate the transport of tryptophan, the precursor of serotonin, in the brain. |
2008-10-24 |
2023-08-12 |
Not clear |
| Vita Dolzan, Alessandro Serretti, Laura Mandelli, Jure Koprivsek, Matej Kastelic, Blanka Kores Plesnica. Acute antipyschotic efficacy and side effects in schizophrenia: association with serotonin transporter promoter genotypes. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 6. 2008-10-22. PMID:18573584. |
the serotonin transporter (5-htt) plays an important role in serotonergic neurotransmission. |
2008-10-22 |
2023-08-12 |
Not clear |
| Luis Galindo-Charles, Salvador Hernandez-Lopez, Elvira Galarraga, Dagoberto Tapia, José Bargas, Julieta Garduño, Carmen Frías-Dominguez, René Drucker-Colin, Stefan Mihailesc. Serotoninergic dorsal raphe neurons possess functional postsynaptic nicotinic acetylcholine receptors. Synapse (New York, N.Y.). vol 62. issue 8. 2008-10-20. PMID:18512214. |
in this study, we asked if functional nachrs are present in serotonergic (5-ht) and nonserotonergic (non-5-ht) neurons of the dorsal raphe nucleus (drn). |
2008-10-20 |
2023-08-12 |
rat |
| b' L Cicin-Sain, S Simaga, A Froebe, M Abrami\\xc4\\x8. Central aminopeptidase and serotonin system activities: possible relationship. Neuropeptides. vol 42. issue 4. 2008-10-20. PMID:18547641.' |
the co-localization of serotonin (5-hydroxytryptamine, 5ht) and neuroactive peptides in the same neuron points to the importance of interactions between serotonergic and peptidergic systems in maintaining body homeostasis. |
2008-10-20 |
2023-08-12 |
rat |
| Xiaoying Lu, Brendon Ross, Manuel Sanchez-Alavez, Eric P Zorrilla, Tamas Bartfa. Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests. Neuropeptides. vol 42. issue 4. 2008-10-20. PMID:18554714. |
we have previously shown that chronic antidepressant treatments increase the binding of a galr2-preferring ligand, galanin (2-11), to the dorsal raphe nucleus (drn) of the rat, which, along with the finding that intra-drn infusion of galanin (2-11) increases the release of serotonin in the hippocampus, suggests that galr2 signaling might exert antidepressant-like actions by modulating ascending serotonergic outflow. |
2008-10-20 |
2023-08-12 |
mouse |
| Therese M Eriksson, Nather Madjid, Elin Elvander-Tottie, Oliver Stiedl, Per Svenningsson, Sven Ove Ogre. Blockade of 5-HT 1B receptors facilitates contextual aversive learning in mice by disinhibition of cholinergic and glutamatergic neurotransmission. Neuropharmacology. vol 54. issue 7. 2008-10-14. PMID:18394658. |
serotonergic (5-ht) neurotransmission plays a role in learning and memory processes, but the physiological role of various receptor subtypes is not well characterised. |
2008-10-14 |
2023-08-12 |
mouse |
| Aude'marie Limacher, Adhil Bhagwandin, Kjell Fuxe, Paul R Mange. Nuclear organization and morphology of cholinergic, putative catecholaminergic and serotonergic neurons in the brain of the Cape porcupine (Hystrix africaeaustralis): increased brain size does not lead to increased organizational complexity. Journal of chemical neuroanatomy. vol 36. issue 1. 2008-10-14. PMID:18472246. |
the distribution, morphology and nuclear organization of the cholinergic, putative catecholaminergic and serotonergic systems within the brain of the cape porcupine (hystrix africaeaustralis) were identified following immunohistochemistry for choline acetyltransferase, tyrosine hydroxylase and serotonin. |
2008-10-14 |
2023-08-12 |
rat |
| Andrew K Evans, Niels Reinders, Katie A Ashford, Isabel N Christie, Jonathan B Wakerley, Christopher A Lowr. Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex. European journal of pharmacology. vol 590. issue 1-3. 2008-10-14. PMID:18577382. |
evidence suggests that 5-hydroxytryptamine 1a (5-ht(1a)) receptor-mediated autoregulation of serotonergic neuronal firing rates is impaired in stress-related neuropsychiatric disorders. |
2008-10-14 |
2023-08-12 |
rat |