| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karl Ebner, Georg M Singewald, Nigel Whittle, Francesco Ferraguti, Nicolas Singewal. Neurokinin 1 receptor antagonism promotes active stress coping via enhanced septal 5-HT transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 8. 2008-09-02. PMID:17957216. |
this effect seems to be mediated by enhanced intraseptal serotonergic transmission via serotonin (5-ht)1a receptors since nk1r blockade reversed the swim stress-induced decrease to an increase in extracellular 5-ht efflux, and furthermore the behavioral effects of l-822429 were blocked by intraseptal 5-ht1a receptor antagonism. |
2008-09-02 |
2023-08-12 |
rat |
| Karl Ebner, Georg M Singewald, Nigel Whittle, Francesco Ferraguti, Nicolas Singewal. Neurokinin 1 receptor antagonism promotes active stress coping via enhanced septal 5-HT transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 8. 2008-09-02. PMID:17957216. |
a direct heterosynaptic regulation by nk1r on 5-ht release from serotonergic fibers was ruled out by immunocytochemistry at the light and electron microscopic level indicating involvement of gabaergic interneuron(s) in this interaction. |
2008-09-02 |
2023-08-12 |
rat |
| Zhiyuan Ma, Gongliang Zhang, Chris Jenney, Swapna Krishnamoorthy, Rui Ta. Characterization of serotonin-toxicity syndrome (toxidrome) elicited by 5-hydroxy-l-tryptophan in clorgyline-pretreated rats. European journal of pharmacology. vol 588. issue 2-3. 2008-09-02. PMID:18499101. |
patients are at high risk of developing serotonin-toxicity syndrome (toxidrome) when they take multiple serotonergic drugs, particularly co-administered with monoamine oxidase inhibitors or 5-hydroxytryptamine (5-ht) reuptake blockers. |
2008-09-02 |
2023-08-12 |
rat |
| João Paulo Capela, Marion Lautenschlager, Ulrich Dirnagl, Maria Lourdes Bastos, Félix Carvalho, Andreas Meise. 5,7-Dihydroxitryptamine toxicity to serotonergic neurons in serum free raphe cultures. European journal of pharmacology. vol 588. issue 2-3. 2008-09-02. PMID:18519135. |
these results indicate that the mechanism by which 5,7-dht-induces serotonergic neurotoxicity is, at least partially, dependent on the toxin uptake by the serotonin transporter. |
2008-09-02 |
2023-08-12 |
rat |
| Saloua Benmansour, Thierry Deltheil, Jonathan Piotrowski, Lorelei Nicolas, Christelle Reperant, Alain M Gardier, Alan Frazer, Denis J Davi. Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents. European journal of pharmacology. vol 587. issue 1-3. 2008-08-25. PMID:18474368. |
whereas ssris produce rapid blockade of the serotonin transporter (sert) in vitro and in vivo, the onset of an observable clinical effect takes longer to occur and a variety of pharmacological effects caused by antidepressants have been speculated to be involved either in initiating antidepressant effects and/or enhancing their effects on serotonergic transmission so as to cause clinical improvement. |
2008-08-25 |
2023-08-12 |
mouse |
| Laurent Monassier, Marc-André Laplante, Fabrice Jaffré, Pascal Bousquet, Luc Maroteaux, Jacques de Champlai. Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice. Hypertension (Dallas, Tex. : 1979). vol 52. issue 2. 2008-08-22. PMID:18591460. |
therefore, we measured the effects of serotonergic 5-ht(2b) receptor blockade on left-ventricular superoxide anion generation in 2 established pharmacological models of cardiac hypertrophy, ie, angiotensin ii and isoproterenol infusions in mice. |
2008-08-22 |
2023-08-12 |
mouse |
| Adhil Bhagwandin, Kjell Fuxe, Nigel C Bennett, Paul R Mange. Nuclear organization and morphology of cholinergic, putative catecholaminergic and serotonergic neurons in the brains of two species of African mole-rat. Journal of chemical neuroanatomy. vol 35. issue 4. 2008-08-21. PMID:18407460. |
the distribution, morphology and nuclear subdivisions of the cholinergic, putative catecholaminergic and serotonergic systems within the brains of two species of african mole-rat (cape dune mole-rat -bathyergus suillus; highveld mole-rat -cryptomys hottentotuspretoriae) were identified following immunohistochemistry for acetylcholinesterase, tyrosine hydroxylase and serotonin. |
2008-08-21 |
2023-08-12 |
rat |
| M Berner Hansen, A-B Witt. The role of serotonin in intestinal luminal sensing and secretion. Acta physiologica (Oxford, England). vol 193. issue 4. 2008-08-20. PMID:18462271. |
a transmembrane serotonin transporter terminates epithelial serotonergic signalling. |
2008-08-20 |
2023-08-12 |
Not clear |
| Enzo Emanuele, Natascia Brondino, Marco Bertona, Simona Re, Diego Gerold. Relationship between platelet serotonin content and rejections of unfair offers in the ultimatum game. Neuroscience letters. vol 437. issue 2. 2008-08-18. PMID:18448251. |
we hypothesize that serotonergic activity, as measured by platelet serotonin levels, will differentiate subjects who either reject or accept low ug offers. |
2008-08-18 |
2023-08-12 |
human |
| Christine Gerin, Jean-Rene Teilhac, Kristin Smith, Alain Priva. Motor activity induces release of serotonin in the dorsal horn of the rat lumbar spinal cord. Neuroscience letters. vol 436. issue 2. 2008-08-13. PMID:18400395. |
literature highlights that serotonergic descending pathways are implicated in somatosensory functions in the spinal cord and that serotonin (5-ht) in the dorsal horn might play a role in motor function through proprioceptive feedback. |
2008-08-13 |
2023-08-12 |
rat |
| Cécile Fligny, Yves Fromes, Philippe Bonnin, Michèle Darmon, Elisa Bayard, Jean-Marie Launay, Francine Côté, Jacques Mallet, Guilan Vodjdan. Maternal serotonin influences cardiac function in adult offspring. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 22. issue 7. 2008-08-12. PMID:18267982. |
these findings show that cardiac function, through the plasma 5-ht concentration, is influenced by the maternal serotonergic status. |
2008-08-12 |
2023-08-12 |
mouse |
| Yael Dvir, Patrick Smallwoo. Serotonin syndrome: a complex but easily avoidable condition. General hospital psychiatry. vol 30. issue 3. 2008-08-11. PMID:18433663. |
serotonin syndrome is a potentially life-threatening adverse drug reaction caused by excessive serotonergic agonism in central and peripheral nervous system serotonergic receptors (boyer ew, shannon m. the serotonin syndrome. |
2008-08-11 |
2023-08-12 |
Not clear |
| Yael Dvir, Patrick Smallwoo. Serotonin syndrome: a complex but easily avoidable condition. General hospital psychiatry. vol 30. issue 3. 2008-08-11. PMID:18433663. |
the etiology is often the result of therapeutic drug use, intentional overdosing of serotonergic agents or complex interactions between drugs that directly or indirectly modulate the serotonin system (boyer ew, shannon m. the serotonin syndrome. |
2008-08-11 |
2023-08-12 |
Not clear |
| Yael Dvir, Patrick Smallwoo. Serotonin syndrome: a complex but easily avoidable condition. General hospital psychiatry. vol 30. issue 3. 2008-08-11. PMID:18433663. |
due to the increasing availability of agents with serotonergic activity, physicians need to more aware of serotonin syndrome. |
2008-08-11 |
2023-08-12 |
Not clear |
| Ozlem Dogan, Nevzat Yuksel, Mehmet Ali Ergun, Akin Yilmaz, Mustafa N Ilhan, Hatice Ersin Karslioglu, Aysegul Koc, Adnan Menevs. Serotonin transporter gene polymorphisms and sertraline response in major depression patients. Genetic testing. vol 12. issue 2. 2008-08-11. PMID:18452396. |
the serotonin transporter (5-htt) gene is a particularly important candidate for genetic involvement in md disorders owing to its key role in the regulation of serotonergic transmission and is therefore considered to be an interesting candidate in the mechanism of antidepressant drugs. |
2008-08-11 |
2023-08-12 |
human |
| Guillaume Lucas, Vladimir V Rymar, Abbas F Sadikot, Guy Debonne. Further evidence for an antidepressant potential of the selective sigma1 agonist SA 4503: electrophysiological, morphological and behavioural studies. The international journal of neuropsychopharmacology. vol 11. issue 4. 2008-08-08. PMID:18364064. |
we focused more specifically on the influence of sa 4503 on central serotonergic (5-ht) transmission, and on hippocampal cell proliferation. |
2008-08-08 |
2023-08-12 |
Not clear |
| Matthias Vömel, Christian Wegene. Neuroarchitecture of aminergic systems in the larval ventral ganglion of Drosophila melanogaster. PloS one. vol 3. issue 3. 2008-08-08. PMID:18365004. |
we here used gal4-driven marker gene expression and immunocytochemistry to map presumed serotonergic (5-ht), dopaminergic, and tyraminergic/octopaminergic neurons in the thoracic and abdominal neuromeres of the drosophila larval ventral ganglion relying on fasciclin2-immunoreactive tracts as three-dimensional landmarks. |
2008-08-08 |
2023-08-12 |
drosophila_melanogaster |
| Supriya Srinivasan, Leila Sadegh, Ida C Elle, Anne G L Christensen, Nils J Faergeman, Kaveh Ashraf. Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms. Cell metabolism. vol 7. issue 6. 2008-08-07. PMID:18522834. |
we investigated serotonin signaling in c. elegans as a paradigm for neural regulation of energy balance and found that serotonergic regulation of fat is molecularly distinct from feeding regulation. |
2008-08-07 |
2023-08-12 |
caenorhabditis_elegans |
| Kerstin Malmberg, Hanna-Linn Wargelius, Paul Lichtenstein, Lars Oreland, Jan-Olov Larsso. ADHD and Disruptive Behavior scores - associations with MAO-A and 5-HTT genes and with platelet MAO-B activity in adolescents. BMC psychiatry. vol 8. 2008-08-06. PMID:18430257. |
we have, in a population-based sample, studied associations between dimensions of the adhd/dbd phenotype and monoamine oxidase b (mao-b) activity in platelets and polymorphisms in two serotonergic genes: the monoamine oxidase a variable number of tandem repeats (mao-a vntr) and the 5-hydroxytryptamine transporter gene-linked polymorphic region (5-htt lpr). |
2008-08-06 |
2023-08-12 |
Not clear |
| Sevda Ozkardesler, Tugba Gurpinar, Mert Akan, Ugur Koca, Huriye Sarikaya, Tulay Olmez, Zahide Ela. A possible perianesthetic serotonin syndrome related to intrathecal fentanyl. Journal of clinical anesthesia. vol 20. issue 2. 2008-08-04. PMID:18410872. |
serotonin syndrome occurs with selective serotonin reuptake inhibitors, opioids, and other serotonergic agents. |
2008-08-04 |
2023-08-12 |
Not clear |