| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Russel S Falck, Jichuan Wang, Robert G Carlso. Depressive symptomatology in young adults with a history of MDMA use: a longitudinal analysis. Journal of psychopharmacology (Oxford, England). vol 22. issue 1. 2008-05-22. PMID:18187532. |
research suggests that methylenedioxymethamphetamine (mdma)/;ecstasy' can cause serotonin depletion as well as serotonergic neurodegradation that may result in depression. |
2008-05-22 |
2023-08-12 |
Not clear |
| Machiko Matsumoto, Hiroko Togashi, Kohtaro Konno, Hiroyo Koseki, Riki Hirata, Takeshi Izumi, Taku Yamaguchi, Mitsuhiro Yoshiok. Early postnatal stress alters the extinction of context-dependent conditioned fear in adult rats. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18262260. |
these results suggest that exposure to early postnatal stress at the third week is responsible for attenuating extinction of contextual fear conditioning and is mediated by a serotonergic 5-ht(1a) receptor mechanism. |
2008-05-20 |
2023-08-12 |
rat |
| Manel J Barbanoj, Jordi Riba, S Clos, S Giménez, E Grasa, S Romer. Daytime Ayahuasca administration modulates REM and slow-wave sleep in healthy volunteers. Psychopharmacology. vol 196. issue 2. 2008-05-19. PMID:18030450. |
dmt interacts with serotonergic neurotransmission acting as a partial agonist at 5-ht(1a) and 5-ht(2a/2c) receptor sites. |
2008-05-19 |
2023-08-12 |
human |
| Astrid C E Linthorst, Cornelia Flachskamm, Johannes M H M Reu. Water temperature determines neurochemical and behavioural responses to forced swim stress: an in vivo microdialysis and biotelemetry study in rats. Stress (Amsterdam, Netherlands). vol 11. issue 2. 2008-05-16. PMID:17853068. |
comparing the serotonergic and core body temperature changes revealed that a combination of two different 5-ht and 5-hiaa responses seems to shape the neurotransmitter response. |
2008-05-16 |
2023-08-12 |
rat |
| F D Zepf, M Holtmann, C Stadler, L Demisch, M Schmitt, L Wöckel, F Poustk. Diminished serotonergic functioning in hostile children with ADHD: tryptophan depletion increases behavioural inhibition. Pharmacopsychiatry. vol 41. issue 2. 2008-05-13. PMID:18311686. |
serotonergic (5-ht) functioning has been shown to account for a variety of behavioural characteristics, in particular aggressive and impulsive behaviour. |
2008-05-13 |
2023-08-12 |
Not clear |
| Patrícia S Brocardo, Josiane Budni, Manuella P Kaster, Adair R S Santos, Ana Lúcia S Rodrigue. Folic acid administration produces an antidepressant-like effect in mice: evidence for the involvement of the serotonergic and noradrenergic systems. Neuropharmacology. vol 54. issue 2. 2008-05-12. PMID:18078962. |
overall, the results firstly indicate that folic acid produced an antidepressant-like effect in fst and in tst and that this effect appears to be mediated by an interaction with the serotonergic (5-ht(1a) and 5-ht(2a/2c) receptors) and noradrenergic (alpha(1)- and alpha(2)-adrenoceptors) systems. |
2008-05-12 |
2023-08-12 |
mouse |
| I C Ferraz, R Boerngen-Lacerd. Serotonin 5-HT2 receptor antagonist does not reverse established ethanol-induced sensitization but blocks its development and expression. Pharmacology, biochemistry, and behavior. vol 88. issue 4. 2008-05-08. PMID:17988724. |
serotonergic agents, including serotonin-2 (5-ht(2)) antagonists, reverse cocaine sensitization, but there is no evidence for the same effect with ethanol, although serotonin involvement in ethanol sensitization has been well reported. |
2008-05-08 |
2023-08-12 |
mouse |
| Rui Wang, Ying Xu, Hong-Li Wu, Ying-Bo Li, Yu-Hua Li, Jia-Bin Guo, Xue-Jun L. The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors. European journal of pharmacology. vol 578. issue 1. 2008-05-06. PMID:17942093. |
taken together, these results indicate that the antidepressant-like effect of curcumin in the forced swimming test is related to serotonergic system and may be mediated by, at least in part, an interaction with 5-ht(1a/1b) and 5-ht(2c) receptors. |
2008-05-06 |
2023-08-12 |
Not clear |
| Alicia K Smith, Irina Dimulescu, Virginia R Falkenberg, Supraja Narasimhan, Christine Heim, Suzanne D Vernon, Mangalathu S Rajeeva. Genetic evaluation of the serotonergic system in chronic fatigue syndrome. Psychoneuroendocrinology. vol 33. issue 2. 2008-05-06. PMID:18079067. |
the pathophysiology of cfs remains elusive, although abnormalities in the central nervous system (cns) have been implicated, particularly hyperactivity of the serotonergic (5-hydroxytryptamine; 5-ht) system and hypoactivity of the hypothalamic-pituitary-adrenal (hpa) axis. |
2008-05-06 |
2023-08-12 |
human |
| Alicia K Smith, Irina Dimulescu, Virginia R Falkenberg, Supraja Narasimhan, Christine Heim, Suzanne D Vernon, Mangalathu S Rajeeva. Genetic evaluation of the serotonergic system in chronic fatigue syndrome. Psychoneuroendocrinology. vol 33. issue 2. 2008-05-06. PMID:18079067. |
since alterations in 5-ht signaling can lead to physiologic and behavioral changes, a genetic evaluation of the 5-ht system was undertaken to identify serotonergic markers associated with cfs and potential mechanisms for cns abnormality. |
2008-05-06 |
2023-08-12 |
human |
| Tamás Balázsa, Judit Bíró, Nóra Gullai, Catherine Ledent, Beáta Sperlág. CB1-cannabinoid receptors are involved in the modulation of non-synaptic [3H]serotonin release from the rat hippocampus. Neurochemistry international. vol 52. issue 1-2. 2008-05-05. PMID:17719142. |
relatively selective degeneration of fine serotonergic axons by the neurotoxin parachloramphetamine (pca) reduced significantly the tritium uptake and the evoked [3h]5-ht release. |
2008-05-05 |
2023-08-12 |
mouse |
| Tamás Balázsa, Judit Bíró, Nóra Gullai, Catherine Ledent, Beáta Sperlág. CB1-cannabinoid receptors are involved in the modulation of non-synaptic [3H]serotonin release from the rat hippocampus. Neurochemistry international. vol 52. issue 1-2. 2008-05-05. PMID:17719142. |
our data suggest that a subpopulation of non-synaptic serotonergic afferents express cb1 receptors and activation of these cb1 receptors leads to a decrease in 5-ht release. |
2008-05-05 |
2023-08-12 |
mouse |
| Margus Tõnissaar, Tanel Mällo, Marika Eller, Riina Häidkind, Kadri Kõiv, Jaanus Harr. Rat behavior after chronic variable stress and partial lesioning of 5-HT-ergic neurotransmission: effects of citalopram. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17826880. |
deficits in serotonergic (5-ht-ergic) neurotransmission and stressful life events have been implicated in affective disorders, and chronic variable stress (cvs) can elicit behavioral changes reminiscent of increased emotionality, anxiety and atypical depression after partial 5-ht depletion. |
2008-05-02 |
2023-08-12 |
rat |
| Bankole A Johnson, Martin A Javors, John D Roache, Chamindi Seneviratne, Susan E Bergeson, Nassima Ait-Daoud, Michael A Dawes, Jennie Z M. Can serotonin transporter genotype predict serotonergic function, chronicity, and severity of drinking? Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 1. 2008-05-02. PMID:17950969. |
can serotonin transporter genotype predict serotonergic function, chronicity, and severity of drinking? |
2008-05-02 |
2023-08-12 |
human |
| Hai-Tao Wang, Bin Luo, Yi-Na Huang, Ke-Qing Zhou, Lin Che. Sodium salicylate suppresses serotonin-induced enhancement of GABAergic spontaneous inhibitory postsynaptic currents in rat inferior colliculus in vitro. Hearing research. vol 236. issue 1-2. 2008-05-02. PMID:18222054. |
since serotonin (5-hydroxytryptamine, 5-ht) containing fibers preferentially innervate inhibitory gaba neurons, there exists a possibility that ss causes the imbalance between inhibition and excitation through influencing serotonergic modulation of the gabaergic synaptic transmission. |
2008-05-02 |
2023-08-12 |
rat |
| Anupom Borah, Kochupurackal P Mohanakuma. Long-term L-DOPA treatment causes indiscriminate increase in dopamine levels at the cost of serotonin synthesis in discrete brain regions of rats. Cellular and molecular neurobiology. vol 27. issue 8. 2008-05-01. PMID:17934805. |
in the present study we investigated 5-hydroxytryptamine (5-ht) and dopamine concentrations in serotonergic and dopaminergic nuclei following chronic administration of l-dopa to find whether the neurotransmitter synthesis in these brain areas are compensated. |
2008-05-01 |
2023-08-12 |
rat |
| Anupom Borah, Kochupurackal P Mohanakuma. Long-term L-DOPA treatment causes indiscriminate increase in dopamine levels at the cost of serotonin synthesis in discrete brain regions of rats. Cellular and molecular neurobiology. vol 27. issue 8. 2008-05-01. PMID:17934805. |
(4) the present results suggest that long-term l-dopa treatment results in significant loss of 5-ht in serotonergic and dopaminergic regions of the brain. |
2008-05-01 |
2023-08-12 |
rat |
| Gabi Koller, Peter Zill, Thomas Skoruppa, Brigitta Bondy, Ulrich W Preuss, Michael Soyk. Low level of harm avoidance is associated with serotonin transporter functional haplotype in alcohol-dependent individuals. Psychiatric genetics. vol 18. issue 2. 2008-04-28. PMID:18349696. |
the serotonin transporter gene (slc6a4) encodes a trans-membrane protein (5-htt) that plays an important role in regulating serotonergic neurotransmission, which is known to be involved in many psychiatric disorders. |
2008-04-28 |
2023-08-12 |
Not clear |
| Sarika Dwarika, Busisiwe C Maseko, Amadi O Ihunwo, Kjell Fuxe, Paul R Mange. Distribution and morphology of putative catecholaminergic and serotonergic neurons in the brain of the greater canerat, Thryonomys swinderianus. Journal of chemical neuroanatomy. vol 35. issue 1. 2008-04-22. PMID:17884333. |
the distribution, morphology and nuclear subdivisions of the putative catecholaminergic and serotonergic systems within the brain of the greater canerat (sometimes spelt cane rat) were identified following immunohistochemistry for tyrosine hydroxylase and serotonin. |
2008-04-22 |
2023-08-12 |
rat |
| L Chen, K K L Yung, Y S Chan, W H Yun. 5-HT excites globus pallidus neurons by multiple receptor mechanisms. Neuroscience. vol 151. issue 2. 2008-04-15. PMID:18082329. |
anatomical and neurochemical studies indicated that the globus pallidus receives serotonergic innervation from raphe nuclei but the membrane effects of 5-ht on globus pallidus neurons are not entirely clear. |
2008-04-15 |
2023-08-12 |
rat |