| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marika Paaver, Niklas Nordquist, Jüri Parik, Maarike Harro, Lars Oreland, Jaanus Harr. Platelet MAO activity and the 5-HTT gene promoter polymorphism are associated with impulsivity and cognitive style in visual information processing. Psychopharmacology. vol 194. issue 4. 2008-03-17. PMID:17628790. |
both low platelet monoamine oxidase (mao) activity and the short (s) allele of the serotonin transporter gene promoter region polymorphism (5-httlpr) are proposed to be markers of less efficient serotonergic functioning. |
2008-03-17 |
2023-08-12 |
Not clear |
| N G Hatcher, X Zhang, J N Stuart, L L Moroz, J V Sweedler, R Gillett. 5-HT and 5-HT-SO4, but not tryptophan or 5-HIAA levels in single feeding neurons track animal hunger state. Journal of neurochemistry. vol 104. issue 5. 2008-03-14. PMID:18036151. |
5-ht and related indole metabolites were measured in single, well-characterized serotonergic neurons of the feeding motor network of the predatory sea-slug pleurobranchaea californica. |
2008-03-14 |
2023-08-12 |
Not clear |
| Nadja Spitzer, Donald H Edwards, Deborah J Bar. Conservation of structure, signaling and pharmacology between two serotonin receptor subtypes from decapod crustaceans, Panulirus interruptus and Procambarus clarkii. The Journal of experimental biology. vol 211. issue Pt 1. 2008-03-13. PMID:18083737. |
the actions of 5-ht have been well characterized for several crustacean model circuits; however, a dissection of the serotonergic transduction cascades operating in these models has been hampered by the lack of pharmacological tools for invertebrate receptors. |
2008-03-13 |
2023-08-12 |
lobster |
| Stephen J Kish, Junchao Tong, Oleh Hornykiewicz, Ali Rajput, Li-Jan Chang, Mark Guttman, Yoshiaki Furukaw. Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease. Brain : a journal of neurology. vol 131. issue Pt 1. 2008-03-06. PMID:17956909. |
interest in serotonergic involvement in parkinson's disease (pd) has focussed recently on the possibility that the remaining serotonin neurons innervating striatum (caudate and putamen) might release dopamine as a 'false transmitter'--an action that could have both beneficial and harmful (e.g. |
2008-03-06 |
2023-08-12 |
Not clear |
| Stephen J Kish, Junchao Tong, Oleh Hornykiewicz, Ali Rajput, Li-Jan Chang, Mark Guttman, Yoshiaki Furukaw. Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease. Brain : a journal of neurology. vol 131. issue Pt 1. 2008-03-06. PMID:17956909. |
evidence for a brain serotonergic disturbance in pd is derived in large part from findings of decreased binding of different radioligands to the serotonin transporter (sert), one 'marker' of serotonin neurons. |
2008-03-06 |
2023-08-12 |
Not clear |
| Larry M Jordan, Jun Liu, Peter B Hedlund, Turgay Akay, Keir G Pearso. Descending command systems for the initiation of locomotion in mammals. Brain research reviews. vol 57. issue 1. 2008-03-05. PMID:17928060. |
neurons in the brainstem implicated in the initiation of locomotion include glutamatergic, noradrenergic (na), dopaminergic (da), and serotonergic (5-ht) neurons giving rise to descending tracts. |
2008-03-05 |
2023-08-12 |
mouse |
| Yoshihisa Kitamura, Kazuhiko Shibata, Kozue Akiyama, Shizue Kimoto, Yoshika Fujitani, Kouhei Kitagawa, Hirotaka Kanzaki, Mamoru Ouchida, Kenji Shimizu, Hiromu Kawasaki, Toshiaki Sendo, Yutaka Gomit. Increased DOI-induced wet-dog shakes in adrenocorticotropic hormone-treated rats are not affected by chronic imipramine treatment: possible involvement of enhanced 5-HT(2A)-receptor expression in the frontal cortex. Journal of pharmacological sciences. vol 106. issue 1. 2008-03-04. PMID:18187923. |
these findings suggest that chronic treatment with acth acts to increase 5-ht(2a)-receptor synthesis through increased gene transcription, without modulating presynaptic serotonergic neurotransmission. |
2008-03-04 |
2023-08-12 |
rat |
| Roberto Mandrioli, Maria Augusta Ragg. Electrodriven methods for the enantioseparation of second-generation antidepressant drugs: an update. Electrophoresis. vol 29. issue 1. 2008-02-28. PMID:18040994. |
in particular, the focus has been put on selective serotonin reuptake inhibitors such as citalopram and sertraline, noradrenergic and specific serotonergic antidepressants, such as mirtazapine and tetracyclic antidepressants such as mianserin, as well as on multianalyte methods. |
2008-02-28 |
2023-08-12 |
Not clear |
| Jean-Pol Tassi. Uncoupling between noradrenergic and serotonergic neurons as a molecular basis of stable changes in behavior induced by repeated drugs of abuse. Biochemical pharmacology. vol 75. issue 1. 2008-02-26. PMID:17686465. |
later on, it was shown that not only noradrenergic but also serotonergic systems, through 5-ht(2a) receptors, were controlling behavioral effects of drugs of abuse. |
2008-02-26 |
2023-08-12 |
mouse |
| Jean-Pol Tassi. Uncoupling between noradrenergic and serotonergic neurons as a molecular basis of stable changes in behavior induced by repeated drugs of abuse. Biochemical pharmacology. vol 75. issue 1. 2008-02-26. PMID:17686465. |
more recently, experiments performed in animals knockout for alpha1b-adrenergic or 5-ht(2a) receptors indicated that noradrenergic and serotonergic neurons, besides their activating effects, inhibit each other by means of the stimulation of alpha1b-adrenergic and 5-ht(2a) receptors and that this mutual inhibition vanishes in wild type mice with repeated injections of psychostimulants, opiates or alcohol. |
2008-02-26 |
2023-08-12 |
mouse |
| Bankole A Johnso. Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings. Biochemical pharmacology. vol 75. issue 1. 2008-02-26. PMID:17880925. |
serotonergic agents such as selective serotonin reuptake inhibitors and the serotonin-3 receptor antagonist, ondansetron, appear to be efficacious only among certain genetic subtypes of alcoholic. |
2008-02-26 |
2023-08-12 |
Not clear |
| Jean-Martin Beaulieu, Xiaodong Zhang, Ramona M Rodriguiz, Tatyana D Sotnikova, Michael J Cools, William C Wetsel, Raul R Gainetdinov, Marc G Caro. Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 4. 2008-02-25. PMID:18212115. |
despite treatment of these conditions with serotonergic drugs, the molecular mechanisms by which 5-ht is involved in the regulation of aberrant emotional behaviors are poorly understood. |
2008-02-25 |
2023-08-12 |
mouse |
| Sébastien Zanella, Françoise Watrin, Saïda Mebarek, Fabienne Marly, Michel Roussel, Catherine Gire, Gwenaëlle Diene, Maïté Tauber, Françoise Muscatelli, Gérard Hilair. Necdin plays a role in the serotonergic modulation of the mouse respiratory network: implication for Prader-Willi syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 7. 2008-02-25. PMID:18272695. |
because serotonin is known to contribute to cns development and to affect maturation and function of the brainstem respiratory network, we also investigated the serotonergic system with hplc, immunohistochemistry, rabies virus tracing approaches, and primary culture experiments. |
2008-02-25 |
2023-08-12 |
mouse |
| Sébastien Zanella, Françoise Watrin, Saïda Mebarek, Fabienne Marly, Michel Roussel, Catherine Gire, Gwenaëlle Diene, Maïté Tauber, Françoise Muscatelli, Gérard Hilair. Necdin plays a role in the serotonergic modulation of the mouse respiratory network: implication for Prader-Willi syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 7. 2008-02-25. PMID:18272695. |
we report first that necdin-deficiency in mice induces central respiratory deficits reminiscent of prader-willi syndrome (irregular rhythm, frequent apneas, and blunted respiratory regulations), second that necdin is expressed by medullary serotonergic neurons, and third that necdin deficiency alters the serotonergic metabolism, the morphology of serotonin vesicles in medullary serotonergic neurons but not the number of these cells. |
2008-02-25 |
2023-08-12 |
mouse |
| S Haider, S Khaliq, S P Ahmed, D J Halee. Long-term tryptophan administration enhances cognitive performance and increases 5HT metabolism in the hippocampus of female rats. Amino acids. vol 31. issue 4. 2008-02-19. PMID:16699826. |
it has been shown in various studies that increase in serotonergic neurotransmission is associated with increased memory consolidation whereas low brain 5ht impairs memory performance. |
2008-02-19 |
2023-08-12 |
rat |
| b' Philippe Ducrott\\xc3\\xa. [Irritable bowel syndrome: current treatment options]. Presse medicale (Paris, France : 1983). vol 36. issue 11 Pt 2. 2008-02-19. PMID:17490849.' |
among the serotonergic drugs, serotonin 5-ht4 receptors agonists (tegaserod) may be available soon, but the development of 5-ht3 antagonists (alosetron, cilansetron) has been stopped for safety reasons (ischemic colitis and severe constipation). |
2008-02-19 |
2023-08-12 |
Not clear |
| Georg Juckel, Ulrich Hegerl, Ina Giegling, Paraskevi Mavrogiorgou, Jürgen Gallinat, Holger Augustin, Christoph Mulert, Oliver Pogarell, Dan Rujesc. Loudness dependence of auditory evoked potentials is not associated with polymorphisms or haplotypes in the serotonin transporter gene in a community-based sample of German healthy volunteers. Psychiatry research. vol 153. issue 2. 2008-02-19. PMID:17629953. |
three previous studies found an association between the loudness dependence (ld) of the auditory evoked potential n1/p2 component, an indicator of central serotonergic neurotransmission, and a functional variation in the promoter region of the 5-hydroxytryptamine transporter (5-htt) gene (rs4795541 ins/del). |
2008-02-19 |
2023-08-12 |
human |
| Henrik Dam, Erling T Mellerup, Per Plenge, Rosa Winther, Gitta Wörtwei. The serotonin transporter and 5HT2A receptor in rat brain after localized lesions. Neurological research. vol 29. issue 7. 2008-02-19. PMID:17711618. |
the development of depression may include the serotonergic system because selective serotonin reuptake inhibitors (ssris) can be used to treat the depression. |
2008-02-19 |
2023-08-12 |
rat |
| François Dubé, Pascal Amireaul. Local serotonergic signaling in mammalian follicles, oocytes and early embryos. Life sciences. vol 81. issue 25-26. 2008-02-15. PMID:18023821. |
additional serotonergic players, including the 5-ht transporter (sert or slc6a4) expressed in oocytes and embryos, and the 5-ht-producing enzyme tryptophan hydroxylase-1 (tph1) expressed in cumulus cells, now make up a complete and autonomous local serotonergic network. |
2008-02-15 |
2023-08-12 |
mouse |
| François Dubé, Pascal Amireaul. Local serotonergic signaling in mammalian follicles, oocytes and early embryos. Life sciences. vol 81. issue 25-26. 2008-02-15. PMID:18023821. |
this local regulation of reproductive processes by 5-ht in mammals might have derived from better-known, and possibly ancestral, serotonergic networks similarly at play in several primitive animals, and potential implications for human reproduction may also be foreseen. |
2008-02-15 |
2023-08-12 |
mouse |