| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Sano, K Mishima, E Koushi, K Orito, N Egashira, K Irie, K Takasaki, S Katsurabayashi, K Iwasaki, N Uchida, T Egawa, Y Kitamura, R Nishimura, M Fujiwar. Delta 9-tetrahydrocannabinol-induced catalepsy-like immobilization is mediated by decreased 5-HT neurotransmission in the nucleus accumbens due to the action of glutamate-containing neurons. Neuroscience. vol 151. issue 2. 2008-04-15. PMID:18083311. |
this thc-induced catalepsy was inhibited by serotonergic drugs such as 5-hydroxy-l-tryptophan (5-htp), a 5-ht precursor, and 5-methoxy-n,n-dimethyltryptamine (5-meodmt), a 5-ht receptor agonist, as well as by anti-glutamatergic drugs such as mk-801 and amantadine, an n-methyl-d-aspartate (nmda) receptor antagonist. |
2008-04-15 |
2023-08-12 |
rat |
| Kally O'Reilly, Sarah J Bailey, Michelle A Lan. Retinoid-mediated regulation of mood: possible cellular mechanisms. Experimental biology and medicine (Maywood, N.J.). vol 233. issue 3. 2008-04-15. PMID:18296731. |
we suggest that 13-cis-ra treatment may induce depression-related behaviors by decreasing adult neurogenesis and/or altering the expression of components of serotonergic neurotransmitter system, thereby leading to impaired serotonin signaling. |
2008-04-15 |
2023-08-12 |
mouse |
| Junko Yasufuku-Takano, Shigehiro Nakajima, Yasuko Nakajim. Morphological and physiological properties of serotonergic neurons in dissociated cultures from the postnatal rat dorsal raphe nucleus. Journal of neuroscience methods. vol 167. issue 2. 2008-04-11. PMID:17920133. |
serotonin immunocytochemistry revealed that 62% of cultured neurons were serotonergic. |
2008-04-11 |
2023-08-12 |
rat |
| Alessio Molfino, Maurizio Muscaritoli, Antonia Cascino, Francesca Fanfarillo, Alessandra Fava, Giuseppe Bertini, Gennaro Citro, Filippo Rossi Fanelli, Alessandro Lavian. Free tryptophan/large neutral amino acids ratios in blood plasma do not predict cerebral spinal fluid tryptophan concentrations in interleukin-1-induced anorexia. Pharmacology, biochemistry, and behavior. vol 89. issue 1. 2008-04-09. PMID:18045669. |
considering the possible role of the raised csf trp in influencing brain serotonin activity, it is postulated that increased serotonergic neurotransmission could be involved in il-1 induced anorexia. |
2008-04-09 |
2023-08-12 |
rat |
| Angela Müllner, Roman R Gonzenbach, Oli Weinmann, Lisa Schnell, Thomas Liebscher, Martin E Schwa. Lamina-specific restoration of serotonergic projections after Nogo-A antibody treatment of spinal cord injury in rats. The European journal of neuroscience. vol 27. issue 2. 2008-04-08. PMID:18215231. |
we studied the effect of 2 weeks of intrathecal nogo-a antibody application after partial thoracic spinal cord injury on the lamina-specific restitution of the serotonergic (5-ht) raphe-spinal projections to the mid-lumbar grey matter. |
2008-04-08 |
2023-08-12 |
rat |
| Simone M Smits, Cornelle W Noorlander, Martien J H Kas, Geert M J Ramakers, Marten P Smid. Alterations in serotonin signalling are involved in the hyperactivity of Pitx3-deficient mice. The European journal of neuroscience. vol 27. issue 2. 2008-04-08. PMID:18215235. |
serotonergic hyperinnervation was demonstrated by increased [3h]-citalopram autoradiographic binding specifically in the dorsal striatum of adult pitx3-deficient mice, indicating alterations in 5-ht transporter levels that correlated to da dysfunction in pitx3 deficiency. |
2008-04-08 |
2023-08-12 |
mouse |
| Peter M Haddad, Serdar M Dursu. Neurological complications of psychiatric drugs: clinical features and management. Human psychopharmacology. vol 23 Suppl 1. 2008-04-07. PMID:18098217. |
severe cases, termed serotonin syndrome, usually follow the co-prescription of drugs that increase serotonergic transmission by different pathways, for example a monoamine oxidase inhibitor (maoi) and a selective serotonin reuptake inhibitor (ssri). |
2008-04-07 |
2023-08-12 |
Not clear |
| Tilo Görnemann, Sven Jähnichen, Björn Schurad, Klaus Peter Latté, Reinhard Horowski, Johannes Tack, Miroslav Flieger, Heinz H Pert. Pharmacological properties of a wide array of ergolines at functional alpha(1)-adrenoceptor subtypes. Naunyn-Schmiedeberg's archives of pharmacology. vol 376. issue 5. 2008-04-03. PMID:18066532. |
in contrast to their affinity at serotonergic (5-ht) and dopaminergic receptor subtypes, only limited information is available concerning their interaction with alpha-adrenoceptor subtypes. |
2008-04-03 |
2023-08-12 |
rat |
| Samina Bano, Shazia Dawoo. Serotonergic mediation effects of St John's wort in rats subjected to swim stress. Pakistan journal of pharmaceutical sciences. vol 21. issue 1. 2008-04-03. PMID:18166522. |
it is concluded that sjw treatment alter stress induced augmented 5-ht levels by decreasing precursor availability to the brain and that serotonergic system is involve in the mechanism of action of the drug. |
2008-04-03 |
2023-08-12 |
rat |
| X Fang, S Liu, X-Y Wang, N Gao, H-Z Hu, G-D Wang, C H Cook, B J Needleman, D J Mikami, Y Xia, G-J Fei, G A Hicks, J D Woo. Neurogastroenterology of tegaserod (HTF 919) in the submucosal division of the guinea-pig and human enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 20. issue 1. 2008-04-01. PMID:17973634. |
actions of the 5-ht(4) serotonergic receptor partial agonist, tegaserod, were investigated on mucosal secretion in the guinea-pig and human small intestine and on electrophysiological behaviour of secretomotor neurons in the guinea-pig small intestinal submucosal plexus. |
2008-04-01 |
2023-08-12 |
human |
| Klas Nordlind, Efrain C Azmitia, Andrzej Slominsk. The skin as a mirror of the soul: exploring the possible roles of serotonin. Experimental dermatology. vol 17. issue 4. 2008-04-01. PMID:18177349. |
the interactions of 5-ht with these various proteins determines the nature, magnitude and duration of serotonergic responses. |
2008-04-01 |
2023-08-12 |
human |
| René Hurlemann, Andreas Matusch, Kai-Uwe Kuhn, Julia Berning, David Elmenhorst, Oliver Winz, Heike Kolsch, Karl Zilles, Michael Wagner, Wolfgang Maier, Andreas Baue. 5-HT2A receptor density is decreased in the at-risk mental state. Psychopharmacology. vol 195. issue 4. 2008-03-31. PMID:17899021. |
current perspectives on the pathophysiology of schizophrenia direct attention to serotonergic (serotonin, 5-ht) dysregulation in the prodrome or at-risk mental state (arms). |
2008-03-31 |
2023-08-12 |
Not clear |
| Christine Norra, Stefanie Becker, Sabine C Herpertz, Hanns Jürgen Kuner. Effects of experimental acute tryptophan depletion on acoustic startle response in females. European archives of psychiatry and clinical neuroscience. vol 258. issue 1. 2008-03-31. PMID:17902001. |
previous studies suggest an important role for serotonergic (5-ht) modulation of the acoustic startle reflex (asr) and prepulse inhibition (ppi). |
2008-03-31 |
2023-08-12 |
human |
| Oliver Pogarell, Walter Koch, Nadine Schaaff, Gabriele Pöpperl, Christoph Mulert, Georg Juckel, Hans-Jürgen Möller, Ulrich Hegerl, Klaus Tatsc. [123I] ADAM brainstem binding correlates with the loudness dependence of auditory evoked potentials. European archives of psychiatry and clinical neuroscience. vol 258. issue 1. 2008-03-31. PMID:17990053. |
the loudness dependence of auditory evoked potentials (ld) has been proposed as an indirect indicator of cortical serotonergic activity, whereas single photon emission computed tomography (spect) and [123i]adam allow the selective assessment of brain serotonin transporters (sert). |
2008-03-31 |
2023-08-12 |
human |
| Xiaoqun Zhang, Per E Andren, Paul Greengard, Per Svenningsso. Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 6. 2008-03-31. PMID:18256188. |
there is a strong serotonin innervation of the striatum by serotonergic neurons that remains relatively preserved in pd. |
2008-03-31 |
2023-08-12 |
mouse |
| Kristofer Thorslund, Klas Nordlin. Serotonergic drugs--a possible role in the treatment of psoriasis? Drug news & perspectives. vol 20. issue 8. 2008-03-27. PMID:18080039. |
5-ht 1a receptor-positive mast cells, and 5-ht 2a receptor and serotonin reuptake transporter (sert)-positive t lymphocytes may be targets for therapy with serotonergic drugs in psoriasis. |
2008-03-27 |
2023-08-12 |
Not clear |
| Jessica E Tanis, James J Moresco, Robert A Lindquist, Michael R Koell. Regulation of serotonin biosynthesis by the G proteins Galphao and Galphaq controls serotonin signaling in Caenorhabditis elegans. Genetics. vol 178. issue 1. 2008-03-27. PMID:18202365. |
to analyze mechanisms that modulate serotonin signaling, we investigated how caenorhabditis elegans regulates the function of serotonergic motor neurons that stimulate egg-laying behavior. |
2008-03-27 |
2023-08-12 |
caenorhabditis_elegans |
| João Manuel Braz, Allan I Basbau. Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits. The Journal of comparative neurology. vol 507. issue 6. 2008-03-27. PMID:18273889. |
despite the evidence for a significant contribution of brainstem serotonergic (5ht) systems to the control of spinal cord "pain" transmission neurons, attention has turned recently to the influence of nonserotonergic neurons, including the facilitatory and inhibitory controls that originate from so-called "on" and "off" cells of the rostroventral medulla (rvm). |
2008-03-27 |
2023-08-12 |
Not clear |
| W Otten, E Kanitz, M Tuchscherer, K-P Brüssow, G Nürnber. Repeated administrations of adrenocorticotropic hormone during late gestation in pigs: maternal cortisol response and effects on fetal HPA axis and brain neurotransmitter systems. Theriogenology. vol 69. issue 3. 2008-03-20. PMID:17983648. |
however, in hippocampus, serotonergic activity was increased in fetuses from acth-treated mothers as shown by significantly elevated 5-hydroxytryptamine (5-ht) levels. |
2008-03-20 |
2023-08-12 |
Not clear |
| Christine Norra, Stefanie Becker, Anno Bröcheler, Wolfram Kawohl, Hanns Jürgen Kunert, Helmut Buchne. Loudness dependence of evoked dipole source activity during acute serotonin challenge in females. Human psychopharmacology. vol 23. issue 1. 2008-03-18. PMID:17868194. |
direct challenge of cortical serotonergic (5-hydroxytryptamine, 5-ht) availability by tryptophan depletion test (tdt) was used to assess the hypothesized inverse relationship between central 5-ht function and loudness dependence of auditory evoked potentials (ldaeps). |
2008-03-18 |
2023-08-12 |
Not clear |