| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sladjana Dronjak, Natasa Spasojevic, Ljubica Gavrilovic, Vladislav Varagi. Effects of noradrenaline and serotonin reuptake inhibitors on pituitary-adrenocortical and sympatho-adrenomedullar system of adult rats. Neuro endocrinology letters. vol 28. issue 5. 2008-02-11. PMID:17984940. |
to estimate the influence of long-term treatment with noradrenergic and serotonergic reuptake inhibitors on activity of pituitary-adrenocortical and sympatho-adrenomedullar systems in animals, we compared the effects of maprotiline (a selective inhibitor of noradrenaline reuptake) and fluxilan (a selective inhibitor of serotonin reuptake) on plasma noradrenaline (na), adrenaline (a), adrenocorticotropic hormone (acth) and corticosterone (cort) levels in unstressed control and rats exposed to chronic unpredictable mild stress (cums). |
2008-02-11 |
2023-08-12 |
rat |
| Jong-Ju Lee, Eu-Teum Hahm, Choong-Hyun Lee, Young-Wuk Ch. Serotonergic modulation of GABAergic and glutamatergic synaptic transmission in mechanically isolated rat medial preoptic area neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17392733. |
serotonergic inhibition of mipsc frequency was mimicked by (+/-)-8-hydroxy-2-dipropylaminotetralin hydrobromide, a specific 5-ht(1a) receptor agonist, and blocked by 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl] piperazine hydrobromide, a specific 5-ht(1a) receptor antagonist. |
2008-02-06 |
2023-08-12 |
rat |
| Jong-Ju Lee, Eu-Teum Hahm, Choong-Hyun Lee, Young-Wuk Ch. Serotonergic modulation of GABAergic and glutamatergic synaptic transmission in mechanically isolated rat medial preoptic area neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17392733. |
serotonergic inhibition of mepsc frequency was mimicked by cgs 12066b, a specific 5-ht(1b) receptor agonist, and blocked by sb 216641, a specific 5-ht(1b) receptor antagonist. |
2008-02-06 |
2023-08-12 |
rat |
| Rainald Mössner, Nicole Döring, André Scherag, Helmut Schäfer, Beate Herpertz-Dahlmann, Helmut Remschmidt, Eberhard Schulz, Tobias Renner, Christoph Wewetzer, Andreas Warnke, Klaus-Peter Lesch, Susanne Walitz. Transmission disequilibrium analysis of the functional 5-HT3A receptor variant C178T in early-onset obsessive compulsive-disorder. Journal of psychopharmacology (Oxford, England). vol 21. issue 8. 2008-01-29. PMID:17259209. |
apart from the standard treatment with serotonin reuptake inhibitors and behavioural therapy, a 5-ht(3) receptor antagonist has recently been shown to benefit some ocd patients, suggesting the 5-ht(3) receptor as a serotonergic candidate gene in the polygenic aetiology of ocd. |
2008-01-29 |
2023-08-12 |
Not clear |
| Vincent J Aloyo, Kuldip D Dav. Behavioral response to emotional stress in rabbits: role of serotonin and serotonin2A receptors. Behavioural pharmacology. vol 18. issue 7. 2008-01-29. PMID:17912049. |
reduction of central 5-ht levels after treatment with the serotonergic neurotoxin 5,7-dht significantly decreased novelty-elicited head bobs by 40% compared with those in sham-lesioned rabbits, indicating that 5-ht mediates, in part, this behavior. |
2008-01-29 |
2023-08-12 |
dog |
| Marcel D Waldinge. Premature ejaculation: state of the art. The Urologic clinics of North America. vol 34. issue 4. 2008-01-29. PMID:17983899. |
a meta-analysis of all selective serotonin reuptake inhibitors (ssris) and clomipramine studies, which were performed according to current standards of evidence-based medicine, demonstrated a similar efficacy for the daily treatment with the serotonergic antidepressants paroxetine hemihydrate, clomipramine, sertraline, and fluoxetine, with paroxetine hemihydrate exerting the strongest effect on ejaculation. |
2008-01-29 |
2023-08-12 |
Not clear |
| George I Papakostas, Michael E Thase, Maurizio Fava, J Craig Nelson, Richard C Shelto. Are antidepressant drugs that combine serotonergic and noradrenergic mechanisms of action more effective than the selective serotonin reuptake inhibitors in treating major depressive disorder? A meta-analysis of studies of newer agents. Biological psychiatry. vol 62. issue 11. 2008-01-28. PMID:17588546. |
are antidepressant drugs that combine serotonergic and noradrenergic mechanisms of action more effective than the selective serotonin reuptake inhibitors in treating major depressive disorder? |
2008-01-28 |
2023-08-12 |
Not clear |
| Jan Croonenberghs, Annick Wauters, Dirk Deboutte, Robert Verkerk, Simon Scharpe, Michael Mae. Central serotonergic hypofunction in autism: results of the 5-hydroxy-tryptophan challenge test. Neuro endocrinology letters. vol 28. issue 4. 2008-01-24. PMID:17693983. |
in order to assess the central serotonergic turnover in autism, this study examines the cortisol and prolactin responses to administration of l-5-hydroxy-tryptophan (5-htp), the direct precursor of 5-ht in 18 male, post-pubertal, caucasian autistic patients (age 13-19 y.; i.q.>55) and 22 matched healthy volunteers. |
2008-01-24 |
2023-08-12 |
human |
| T Celeste Napier, Erik D Istr. Methamphetamine-induced sensitization includes a functional upregulation of ventral pallidal 5-HT2A/2C receptors. Synapse (New York, N.Y.). vol 62. issue 1. 2008-01-22. PMID:17957734. |
methamphetamine (meth) causes the release of serotonin (5-ht), but little is known about how repeated exposure to meth modifies serotonergic receptor function, especially in the ventral pallidum (vp), a brain region highly innervated by serotonin inputs. |
2008-01-22 |
2023-08-12 |
rat |
| Cassandra M Miller-Butterworth, Jay R Kaplan, M Michael Barmada, Stephen B Manuck, Robert E Ferrel. The serotonin transporter: sequence variation in Macaca fascicularis and its relationship to dominance. Behavior genetics. vol 37. issue 5. 2008-01-18. PMID:17605101. |
specific genotypes of the rhesus monkey and human serotonin transporter gene (sert) promoter region are associated with personality traits and serotonergic activity. |
2008-01-18 |
2023-08-12 |
human |
| Luigi M Pavone, Simona Tafuri, Vincenzo Mastellone, Rossella Della Morte, Pietro Lombardi, Luigi Avallone, Veeramani Maharajan, Norma Staiano, Gaetano Scal. Expression of the serotonin transporter (SERT) in the choroid plexuses from buffalo brain. Anatomical record (Hoboken, N.J. : 2007). vol 290. issue 12. 2008-01-17. PMID:17957753. |
the serotonin transporter (sert) regulates the entire serotonergic system, including serotonin receptors by means of modulation of serotonin concentration in the extracellular fluid. |
2008-01-17 |
2023-08-12 |
Not clear |
| Joseph A Saveika, Jean E Shelto. Cyproheptadine for pediatric intrathecal baclofen withdrawal: a case report. American journal of physical medicine & rehabilitation. vol 86. issue 12. 2008-01-14. PMID:18090440. |
its origin is postulated as an independent form of a serotonergic syndrome occurring from loss of gamma-aminobutyric acid b receptor-mediated inhibition of serotonin. |
2008-01-14 |
2023-08-12 |
Not clear |
| Daniel K Mulkey, Diane L Rosin, Gavin West, Ana C Takakura, Thiago S Moreira, Douglas A Bayliss, Patrice G Guyene. Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 51. 2008-01-14. PMID:18094252. |
coexistence of serotonin and substance p in terminals within rtn confirmed that lower medullary serotonergic neurons innervate rtn. |
2008-01-14 |
2023-08-12 |
Not clear |
| Daniel K Mulkey, Diane L Rosin, Gavin West, Ana C Takakura, Thiago S Moreira, Douglas A Bayliss, Patrice G Guyene. Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 51. 2008-01-14. PMID:18094252. |
thus, rtn neurons presumably contribute to the respiratory stimulation caused by serotonergic neurons, but serotonin seems without effect on the cellular mechanism by which rtn neurons detect ph. |
2008-01-14 |
2023-08-12 |
Not clear |
| E Hame. Serotonin and migraine: biology and clinical implications. Cephalalgia : an international journal of headache. vol 27. issue 11. 2008-01-10. PMID:17970989. |
amongst the many neurotransmitters in the brain, the serotonergic (serotonin, 5-ht) system from the brainstem raphe nucleus has been most convincingly implicated in migraine pathophysiology. |
2008-01-10 |
2023-08-12 |
Not clear |
| E Hame. Serotonin and migraine: biology and clinical implications. Cephalalgia : an international journal of headache. vol 27. issue 11. 2008-01-10. PMID:17970989. |
the documented changes in 5-ht metabolism and in the processing of central 5-ht-mediated responses during and in between migraine attacks have led to the suggestion that migraine is a consequence of a central neurochemical imbalance that involves a low serotonergic disposition. |
2008-01-10 |
2023-08-12 |
Not clear |
| E Hame. Serotonin and migraine: biology and clinical implications. Cephalalgia : an international journal of headache. vol 27. issue 11. 2008-01-10. PMID:17970989. |
although the exact cascade of events that link abnormal serotonergic neurotransmission to the manifestation of head pain and the accompanying symptoms has yet to be fully understood, recent evidence suggests that a low 5-ht state facilitates activation of the trigeminovascular nociceptive pathway, as induced by cortical spreading depression. |
2008-01-10 |
2023-08-12 |
Not clear |
| Andreas Reif, Michael Rösler, Christine M Freitag, Marc Schneider, Andrea Eujen, Christian Kissling, Denise Wenzler, Christian P Jacob, Petra Retz-Junginger, Johannes Thome, Klaus-Peter Lesch, Wolfgang Ret. Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 11. 2008-01-09. PMID:17342170. |
the present study aimed at investigating the contribution of polymorphisms shown to moderate transcription of two genes involved in serotonergic neurotransmission (serotonin transporter, 5htt, and monoamine oxidase a, maoa) to the development of violence and to test for gene-environment interactions relating to adverse childhood environment. |
2008-01-09 |
2023-08-12 |
human |
| N Müller, M J Schwar. The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression. Molecular psychiatry. vol 12. issue 11. 2008-01-09. PMID:17457312. |
an enhanced consumption of serotonin and its precursor tryptophan through ido activation could well explain the reduced availability of serotonergic neurotransmission in md. |
2008-01-09 |
2023-08-12 |
Not clear |
| Kohtarou Konno, Machiko Matsumoto, Hiroko Togashi, Taku Yamaguchi, Takeshi Izumi, Masahiko Watanabe, Toshihiko Iwanaga, Mitsuhiro Yoshiok. Early postnatal stress affects the serotonergic function in the median raphe nuclei of adult rats. Brain research. vol 1172. 2008-01-09. PMID:17825274. |
recent studies have focused on the serotonergic mechanism mediated via serotonin (5-ht) receptors underlying regulation of emotional stress during the developmental period. |
2008-01-09 |
2023-08-12 |
rat |