Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
MaKenna Y Cealie, James C Douglas, Hannah K Swan, Erik D Vonkaenel, Matthew N McCall, Paul D Drew, Ania K Majewsk. Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum. Cells. vol 13. issue 5. 2024-03-13. PMID:38474350. |
developmental ethanol exposure impacts purkinje cells but not microglia in the young adult cerebellum. |
2024-03-13 |
2024-03-15 |
mouse |
MaKenna Y Cealie, James C Douglas, Hannah K Swan, Erik D Vonkaenel, Matthew N McCall, Paul D Drew, Ania K Majewsk. Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum. Cells. vol 13. issue 5. 2024-03-13. PMID:38474350. |
to determine how developmental ethanol exposure affects adult cerebellar microglia and purkinje cells, we used a human third-trimester binge exposure model in which mice received ethanol or saline from postnatal (p) days 4-9. |
2024-03-13 |
2024-03-15 |
mouse |
MaKenna Y Cealie, James C Douglas, Hannah K Swan, Erik D Vonkaenel, Matthew N McCall, Paul D Drew, Ania K Majewsk. Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum. Cells. vol 13. issue 5. 2024-03-13. PMID:38474350. |
in adolescence, cerebellar cranial windows were implanted and mice were aged to young adulthood for examination of microglia and purkinje cells in vivo with two-photon imaging or in fixed tissue. |
2024-03-13 |
2024-03-15 |
mouse |
MaKenna Y Cealie, James C Douglas, Hannah K Swan, Erik D Vonkaenel, Matthew N McCall, Paul D Drew, Ania K Majewsk. Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum. Cells. vol 13. issue 5. 2024-03-13. PMID:38474350. |
overall, developmental ethanol exposure had few effects on cerebellar microglia in young adulthood and purkinje cells appeared to be more susceptible to its effects. |
2024-03-13 |
2024-03-15 |
mouse |
Tsubasa Itoh, Mari Uehara, Shinnosuke Yura, Jui Chun Wang, Yukimi Fujii, Akiko Nakanishi, Takashi Shimizu, Masahiko Hib. Foxp- and Skor-family proteins control differentiation of Purkinje cells from Ptf1a and Neurogenin1-expressing progenitors in zebrafish. Development (Cambridge, England). 2024-03-08. PMID:38456494. |
cerebellar neurons, such as gabaergic purkinje cells (pcs), interneurons (ins), and glutamatergic granule cells (gcs) are differentiated from neural progenitors expressing proneural genes including ptf1a, neurogenin1, and atoh1a/b/c. |
2024-03-08 |
2024-03-10 |
zebrafish |
Mauliza Mauliza, Herlina Dimiati, Muslim Akmal, Imran Imra. Role of forkhead box protein 2 (FOXP2) in oral-motor abilities of preterm infants: A brief literature review. Narra J. vol 3. issue 2. 2024-03-07. PMID:38450264. |
the oral feeding development involves forkhead box protein 2 (foxp2)-expressing neurons that are found in the deep layers of the cortex, basal ganglia, parts of the thalamus and purkinje cells of the cerebellum. |
2024-03-07 |
2024-03-09 |
Not clear |
Qiong Wu, Qing-Yun Huang, Guo-He Ta. [Abnormalities in signal transduction of Purkinje cells in spinocerebellar ataxias: a review]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 1. 2024-03-06. PMID:38444133. |
purkinje neuronal degeneration and cerebellar atrophy are common pathological features among most sca subtypes. |
2024-03-06 |
2024-03-08 |
Not clear |
Qiong Wu, Qing-Yun Huang, Guo-He Ta. [Abnormalities in signal transduction of Purkinje cells in spinocerebellar ataxias: a review]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 1. 2024-03-06. PMID:38444133. |
the physiological functions of purkinje cells are regulated by multiple factors, and their dysfunction in signal transduction may lead to abnormal cerebellar motor control. |
2024-03-06 |
2024-03-08 |
Not clear |
Zi-Hao Li, Bin Li, Xiao-Yang Zhang, Jing-Ning Zh. Neuropeptides and Their Roles in the Cerebellum. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38397008. |
moreover, cerebellar neuropeptides have also been revealed to be involved in the neurogenetic and developmental regulation of the developing cerebellum, including survival, migration, differentiation, and maturation of the purkinje cells and granule cells in the cerebellar cortex. |
2024-02-24 |
2024-02-26 |
Not clear |
Igor Gonçalves de Oliveira, Letícia Yoshitome Queiroz, Carla Cristiane Soares da Silva, Sabrina Carvalho Cartágenes, Luanna Melo Pereira Fernandes, Fábio José Coelho de Souza-Junior, Leonardo Oliveira Bittencourt, Rafael Rodrigues Lima, Manoela Domingues Martins, Tuany Rafaeli Schmidt, Enéas Andrade Fontes-Junior, Cristiane do Socorro Ferraz Mai. Ethanol binge drinking exposure during adolescence displays long-lasting motor dysfunction related to cerebellar neurostructural damage even after long-term withdrawal in female Wistar rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 173. 2024-02-23. PMID:38394853. |
our findings demonstrate that the adolescent binge drinking exposure paradigm induced cerebellar cell loss in all stages evaluated, measured through the reduction of purkinje's cell density and granular layer neurons. |
2024-02-23 |
2024-02-26 |
rat |
Ping He, Shuting Zhong, Shuaijun Lin, Zhiyan Xia, Liqing Wang, Yuhe Han, Di Xu, Shuping Hu, Xiaokun Li, Peijun Li, Cong Wan. FGF9 is required for Purkinje cell development and function in the cerebellum. iScience. vol 27. issue 2. 2024-02-14. PMID:38352230. |
together, the data demonstrate that neuronal fgf9 is required for the development and function of purkinje cells in the cerebellum. |
2024-02-14 |
2024-02-16 |
Not clear |
Maxime Beau, David J Herzfeld, Francisco Naveros, Marie E Hemelt, Federico D'Agostino, Marlies Oostland, Alvaro Sánchez-López, Young Yoon Chung, Michael Maibach, Hannah N Stabb, M Gabriela Martínez Lopera, Agoston Lajko, Marie Zedler, Shogo Ohmae, Nathan J Hall, Beverley A Clark, Dana Cohen, Stephen G Lisberger, Dimitar Kostadinov, Court Hull, Michael Häusser, Javier F Medin. A deep-learning strategy to identify cell types across species from high-density extracellular recordings. bioRxiv : the preprint server for biology. 2024-02-14. PMID:38352514. |
we combine optogenetic activation and pharmacology using the cerebellum as a testbed to generate a curated ground-truth library of electrophysiological properties for purkinje cells, molecular layer interneurons, golgi cells, and mossy fibers. |
2024-02-14 |
2024-02-16 |
Not clear |
Sung Won Hur, Karen Safaryan, Long Yang, Hugh T Blair, Sotiris C Masmanidis, Paul J Mathews, Daniel Aharoni, Peyman Golshan. Correlated signatures of social behavior in cerebellum and anterior cingulate cortex. eLife. vol 12. 2024-02-13. PMID:38345922. |
during social behavior, we recorded the spike timing of multiple single units in cerebellar right crus i (rcrus i) purkinje cells (pcs) or dentate nucleus (dn) neurons while synchronously imaging calcium transients in contralateral acc neurons. |
2024-02-13 |
2024-02-15 |
mouse |
Amira El-Helaly, Amoura M Abou-El-Naga, Khulud M Alshehri, Mai Alaa El-Dei. Miracle Tree ( Pakistan journal of biological sciences : PJBS. vol 26. issue 12. 2024-02-09. PMID:38334155. |
<b>conclusion:</b> histological and ultrastructural examinations confirmed the recuperating effects of <i>m. oleifera</i> on mothers' cerebellar tissue intoxicated with fluoride indicated by intact folia and restored purkinje cells number and architecture. |
2024-02-09 |
2024-02-11 |
rat |
Ken-Ichi Dewa, Nariko Arimura, Wataru Kakegawa, Masayuki Itoh, Toma Adachi, Satoshi Miyashita, Yukiko U Inoue, Kento Hizawa, Kei Hori, Natsumi Honjoya, Haruya Yagishita, Shinichiro Taya, Taisuke Miyazaki, Chika Usui, Shoji Tatsumoto, Akiko Tsuzuki, Hirotomo Uetake, Kazuhisa Sakai, Kazuhiro Yamakawa, Takuya Sasaki, Jun Nagai, Yoshiya Kawaguchi, Masaki Sone, Takayoshi Inoue, Yasuhiro Go, Noritaka Ichinohe, Kozo Kaibuchi, Masahiko Watanabe, Schuichi Koizumi, Michisuke Yuzaki, Mikio Hoshin. Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation. Nature communications. vol 15. issue 1. 2024-02-01. PMID:38302444. |
here, we report that down syndrome cell adhesion molecule (dscam) in purkinje cells controls synapse formation and function in the developing cerebellum. |
2024-02-01 |
2024-02-04 |
mouse |
Debananda Sahoo, Anupam Dey, Anil Dash, Arpita Das. Ovarian mass Presenting as Paraneoplastic cerebellar degeneration with peripheral neuropathy and anti-Yo antibody. BMJ case reports. vol 17. issue 1. 2024-01-25. PMID:38272525. |
an immune-mediated attack on the cerebellar purkinje cells and consequent cerebellar symptoms define paraneoplastic cerebellar degeneration(pcd), a subtype of the pns. |
2024-01-25 |
2024-01-28 |
Not clear |
Samar M Ez Elarab, Mohamed A M Alsafy, Samir A A El-Gendy, Neveen E R El-Bakary, Ahmed Elsayed Noreldin, Ahmed M Rashwa. Investigating the role of Purkinje fibers and synaptic connectivity in balance regulation through comprehensive ultrastructural and immunohistochemical analysis of the donkey's (Equus asinus) cerebellum. Journal of experimental zoology. Part A, Ecological and integrative physiology. 2024-01-17. PMID:38229259. |
investigating the role of purkinje fibers and synaptic connectivity in balance regulation through comprehensive ultrastructural and immunohistochemical analysis of the donkey's (equus asinus) cerebellum. |
2024-01-17 |
2024-01-19 |
Not clear |
Samar M Ez Elarab, Mohamed A M Alsafy, Samir A A El-Gendy, Neveen E R El-Bakary, Ahmed Elsayed Noreldin, Ahmed M Rashwa. Investigating the role of Purkinje fibers and synaptic connectivity in balance regulation through comprehensive ultrastructural and immunohistochemical analysis of the donkey's (Equus asinus) cerebellum. Journal of experimental zoology. Part A, Ecological and integrative physiology. 2024-01-17. PMID:38229259. |
the purkinje cells were situated in the intermediate zone of the cerebellum cortex, known as the purkinje cell layer. |
2024-01-17 |
2024-01-19 |
Not clear |
Alexander Atamian, Marcella Birtele, Negar Hosseini, Tuan Nguyen, Anoothi Seth, Ashley Del Dosso, Sandeep Paul, Neil Tedeschi, Ryan Taylor, Marcelo P Coba, Ranmal Samarasinghe, Carlos Lois, Giorgia Quadrat. Human cerebellar organoids with functional Purkinje cells. Cell stem cell. vol 31. issue 1. 2024-01-05. PMID:38181749. |
human cerebellar organoids with functional purkinje cells. |
2024-01-05 |
2024-01-08 |
human |
Robijanto Soetedjo, Gregory D Horwit. Closed-loop optogenetic perturbation of macaque oculomotor cerebellum: evidence for an internal saccade model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-01-05. PMID:38182420. |
to investigate the role of the cerebellum in these two aspects of saccade production, we delivered saccade-triggered light pulses to channelrhodopsin-2-expressing purkinje cells in the oculomotor vermis (omv) of two male macaque monkeys. |
2024-01-05 |
2024-01-08 |
monkey |