| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming-Ming Tang, Wen-Juan Lin, Yu-Qin Pan, Ying-Cong L. Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30135647. |
it was found that fgf2 infusions reversed the lps-induced depressive-like behaviors and inhibited the hippocampal microglia activation. |
2020-09-30 |
2023-08-13 |
rat |
| Tsuyoshi Hashizume, Bo-Kyung Son, Sakiko Taniguchi, Koichi Ito, Yoshihiro Noda, Tamao Endo, Michiko Nanao-Hamai, Sumito Ogawa, Masahiro Akishit. Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction. Scientific reports. vol 9. issue 1. 2020-09-30. PMID:30858535. |
iba1/mhcii-double-positive microglia activation was also seen in the hippocampus, suggesting that vascular inflammation drives neuroinflammation and subsequent cognitive dysfunction. |
2020-09-30 |
2023-08-13 |
mouse |
| Yulia V Dobryakova, Maria N Volobueva, Anna O Manolova, Tatiana M Medvedeva, Alexey A Kvichansky, Natalia V Gulyaeva, Vlamidir A Markevich, Mikhail Yu Stepanichev, Alexey P Bolshako. Cholinergic Deficit Induced by Central Administration of 192IgG-Saporin Is Associated With Activation of Microglia and Cell Loss in the Dorsal Hippocampus of Rats. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:30930730. |
cholinergic deficit induced by central administration of 192igg-saporin is associated with activation of microglia and cell loss in the dorsal hippocampus of rats. |
2020-09-30 |
2023-08-13 |
rat |
| Yulia V Dobryakova, Maria N Volobueva, Anna O Manolova, Tatiana M Medvedeva, Alexey A Kvichansky, Natalia V Gulyaeva, Vlamidir A Markevich, Mikhail Yu Stepanichev, Alexey P Bolshako. Cholinergic Deficit Induced by Central Administration of 192IgG-Saporin Is Associated With Activation of Microglia and Cell Loss in the Dorsal Hippocampus of Rats. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:30930730. |
one and a half months after injection, we studied the histopathology of the hippocampus and the responses of microglia and astrocytes using immunohistochemistry and neuroglial gene expression. |
2020-09-30 |
2023-08-13 |
rat |
| Tanya Miladinovic, Manu Sharma, Andy Phan, Hana Geres, Robert G Ungard, Katja Linher-Melville, Gurmit Sing. Activation of hippocampal microglia in a murine model of cancer-induced pain. Journal of pain research. vol 12. 2020-09-30. PMID:30936739. |
activation of hippocampal microglia in a murine model of cancer-induced pain. |
2020-09-30 |
2023-08-13 |
mouse |
| Raul Chavez-Valdez, Amin Mottahedin, Linnea Stridh, Tracylyn R Yellowhair, Lauren L Jantzie, Frances J Northington, Carina Mallar. Evidence for Sexual Dimorphism in the Response to TLR3 Activation in the Developing Neonatal Mouse Brain: A Pilot Study. Frontiers in physiology. vol 10. 2020-09-30. PMID:30971945. |
a second group of pups were killed at 24 h (p9) or 7 days (p15) after poly i:c to assess astrocytic (gfap) and microglia (iba1) activation in the hippocampus, thalamus and cortex using immunohistochemistry, and gene and protein expression of cytokines/chemokines using real time rt-pcr and msd, respectively (4-6/group). |
2020-09-30 |
2023-08-13 |
mouse |
| Sylvia J Wowro, Giang Tong, Jana Krech, Nele Rolfs, Felix Berger, Katharina R L Schmit. Combined Cyclosporin A and Hypothermia Treatment Inhibits Activation of BV-2 Microglia but Induces an Inflammatory Response in an Ischemia/Reperfusion Hippocampal Slice Culture Model. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31293389. |
combined cyclosporin a and hypothermia treatment inhibits activation of bv-2 microglia but induces an inflammatory response in an ischemia/reperfusion hippocampal slice culture model. |
2020-09-30 |
2023-08-13 |
Not clear |
| Sylvia J Wowro, Giang Tong, Jana Krech, Nele Rolfs, Felix Berger, Katharina R L Schmit. Combined Cyclosporin A and Hypothermia Treatment Inhibits Activation of BV-2 Microglia but Induces an Inflammatory Response in an Ischemia/Reperfusion Hippocampal Slice Culture Model. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31293389. |
therefore, we investigated whether the combination of hypothermia and treatment with csa has neuroprotective effects in an oxygen-glucose deprivation/reperfusion (ogd/r) injury model in neuronal and bv-2 microglia monocultures, as well as in an organotypic hippocampal slice culture (ohsc). |
2020-09-30 |
2023-08-13 |
Not clear |
| Kyung-Ok Cho, Joo Youn Kim, Kyoung Hoon Jeong, Mun-Yong Lee, Seong Yun Ki. Increased expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 after pilocarpine-induced status epilepticus in mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 23. issue 4. 2020-09-30. PMID:31297012. |
at 1 day after se, hippocampal astrocytes and microglia were activated. |
2020-09-30 |
2023-08-13 |
mouse |
| Kyung-Ok Cho, Joo Youn Kim, Kyoung Hoon Jeong, Mun-Yong Lee, Seong Yun Ki. Increased expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 after pilocarpine-induced status epilepticus in mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 23. issue 4. 2020-09-30. PMID:31297012. |
however, at 4 days and 7 days after se, both vegfr-3 and vegf-c immunoreactivities were observed mainly in astrocytes and in some microglia of the stratum radiatum and lacunosum-moleculare of the hippocampus, respectively. |
2020-09-30 |
2023-08-13 |
mouse |
| Kyung-Ok Cho, Joo Youn Kim, Kyoung Hoon Jeong, Mun-Yong Lee, Seong Yun Ki. Increased expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 after pilocarpine-induced status epilepticus in mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 23. issue 4. 2020-09-30. PMID:31297012. |
these data indicate that vegf-c and vegfr-3 can be upregulated in hippocampal astrocytes and microglia after pilocarpine-induced se, providing basic information about vegf-c and vegfr-3 expression patterns following acute seizures. |
2020-09-30 |
2023-08-13 |
mouse |
| Christa Løth Myhre, Camilla Thygesen, Birgitte Villadsen, Jeanette Vollerup, Laura Ilkjær, Katrine Tækker Krohn, Manuela Grebing, Shuainan Zhao, Asif Manzoor Khan, Lasse Dissing-Olesen, Morten Skovgaard Jensen, Alicia A Babcock, Bente Finse. Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31417357. |
microglia express insulin-like growth factor-1 in the hippocampus of aged app insulin-like growth factor-1 (igf-1) is a pleiotropic molecule with neurotrophic and immunomodulatory functions. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ai-Ling Xu, Guan-Yi Zheng, Hui-Ying Ye, Xiao-Dong Chen, Qiong Jian. Characterization of astrocytes and microglial cells in the hippocampal CA1 region after transient focal cerebral ischemia in rats treated with Ilexonin A. Neural regeneration research. vol 15. issue 1. 2020-09-30. PMID:31535655. |
the results of the present study suggest that ilexonin a has a neuroprotective effect in the hippocampus after ischemia/reperfusion, probably through regulating astrocytes and microglia activation, promoting neuronal stem cell proliferation and reducing the levels of pro-inflammatory factors. |
2020-09-30 |
2023-08-13 |
rat |
| Caroline Büttner, Maxi Heer, Jasmin Traichel, Martin Schwemmle, Bernd Heimric. Zika Virus-Mediated Death of Hippocampal Neurons Is Independent From Maturation State. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31551711. |
zikv infection of hippocampal tissue was accompanied by both a profound astrocyte reaction indicating tissue injury and a microglia response suggesting phagocytotic activity. |
2020-09-30 |
2023-08-13 |
mouse |
| Xiujing Feng, Yuan Zhao, Tianyuan Yang, Manyu Song, Chaoran Wang, Yujie Yao, Honggang Fa. Glucocorticoid-Driven NLRP3 Inflammasome Activation in Hippocampal Microglia Mediates Chronic Stress-Induced Depressive-Like Behaviors. Frontiers in molecular neuroscience. vol 12. 2020-09-30. PMID:31555091. |
glucocorticoid-driven nlrp3 inflammasome activation in hippocampal microglia mediates chronic stress-induced depressive-like behaviors. |
2020-09-30 |
2023-08-13 |
rat |
| Xiujing Feng, Yuan Zhao, Tianyuan Yang, Manyu Song, Chaoran Wang, Yujie Yao, Honggang Fa. Glucocorticoid-Driven NLRP3 Inflammasome Activation in Hippocampal Microglia Mediates Chronic Stress-Induced Depressive-Like Behaviors. Frontiers in molecular neuroscience. vol 12. 2020-09-30. PMID:31555091. |
however, the mechanism of nlrp3 inflammasome activation in hippocampal microglia and its role in depressive-like behaviors remain poorly understood. |
2020-09-30 |
2023-08-13 |
rat |
| Dinesh Upadhya, Maheedhar Kodali, Daniel Gitai, Olagide W Castro, Gabriele Zanirati, Raghavendra Upadhya, Sahithi Attaluri, Eeshika Mitra, Bing Shuai, Bharathi Hattiangady, Ashok K Shett. A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology. Aging and disease. vol 10. issue 5. 2020-09-30. PMID:31595192. |
besides, the model showed many neuropathological features of chronic tle, which include a partial loss of inhibitory interneurons, reduced neurogenesis with persistent aberrant migration of newly born neurons, chronic neuroinflammation typified by hypertrophied astrocytes and rod-shaped microglia, and a significant aberrant mossy fiber sprouting in the hippocampus. |
2020-09-30 |
2023-08-13 |
human |
| Ju Zeng, Bin Cheng, Yan Huang, Xiaorui Zhang, Chen Wang, Na Sun, Gang Liu, Xiaorui Cheng, Yongxiang Zhang, Wenxia Zho. Active Fraction Combination from Liuwei Dihuang Decoction (LW-AFC) Alleviated the LPS-Induced Long-Term Potentiation Impairment and Glial Cells Activation in Hippocampus of Mice by Modulating Immune Responses. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-09-30. PMID:31636681. |
the pretreatment with lw-afc had an antipyretic effect on fever and improved the impaired ltp induced by lps, alleviated the microglia and astrocytes activation in the hippocampus, regulated the abnormal t-lymphocyte subpopulation in the spleen and blood caused by lps, and reduced the aberrant secretion of cytokines in the brain and plasma. |
2020-09-30 |
2023-08-13 |
mouse |
| Tianpao Hao, Xiaohong Du, Shen Yang, Yang Zhang, Feiyu Lian. Astrocytes-induced neuronal inhibition contributes to depressive-like behaviors during chronic stress. Life sciences. vol 258. 2020-09-30. PMID:32682917. |
taken together, these results indicate that neuronal inhibition by astrocytes in the mpfc and hippocampus contributed to depressive-like behaviors mediated by activated microglia. |
2020-09-30 |
2023-08-13 |
mouse |
| Alline C Campos, Manoela V Fogaça, Franciele F Scarante, Sâmia R L Joca, Amanda J Sales, Felipe V Gomes, Andreza B Sonego, Naielly S Rodrigues, Ismael Galve-Roperh, Francisco S Guimarãe. Plastic and Neuroprotective Mechanisms Involved in the Therapeutic Effects of Cannabidiol in Psychiatric Disorders. Frontiers in pharmacology. vol 8. 2020-09-29. PMID:28588483. |
for example, cbd attenuates the decrease in hippocampal neurogenesis and dendrite spines density induced by chronic stress and prevents microglia activation and the decrease in the number of parvalbumin-positive gaba neurons in a pharmacological model of schizophrenia. |
2020-09-29 |
2023-08-13 |
Not clear |