| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas Chaaya, Angela Jacques, Arnauld Belmer, Kate Beecher, Syed A Ali, Fatemeh Chehrehasa, Andrew R Battle, Luke R Johnson, Selena E Bartlet. Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31139053. |
contextual fear conditioning alter microglia number and morphology in the rat dorsal hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Nicholas Chaaya, Angela Jacques, Arnauld Belmer, Kate Beecher, Syed A Ali, Fatemeh Chehrehasa, Andrew R Battle, Luke R Johnson, Selena E Bartlet. Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31139053. |
the current study was designed to evaluate how two different contextual fear memories alter amygdala and hippocampus microglia, brain derived neurotrophic factor (bdnf), and phosphorylated cyclic-amp response element binding (pcreb). |
2020-10-01 |
2023-08-13 |
rat |
| Nicholas Chaaya, Angela Jacques, Arnauld Belmer, Kate Beecher, Syed A Ali, Fatemeh Chehrehasa, Andrew R Battle, Luke R Johnson, Selena E Bartlet. Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31139053. |
the unpaired fear conditioning procedure (whereby non-reinforced and non-overlapping auditory tones were provided at random intervals during conditioning), despite producing equivalent levels of fear as the standard procedure, did not alter microglia, bdnf or pcreb number in any dorsal hippocampus or lateral amygdala brain regions. |
2020-10-01 |
2023-08-13 |
rat |
| Teresa Joy, Muddanna S Rao, Sampath Madhyastha, Keshav Pa. Effect of N-Acetyl Cysteine on Intracerebroventricular Colchicine Induced Cognitive Deficits, Beta Amyloid Pathology, and Glial Cells. Neuroscience journal. vol 2019. 2020-10-01. PMID:31139638. |
cognitive function was evaluated in active avoidance test; beta amyloid protein, beta amyloid plaques, astrocytes, and microglia cells were quantified using immunohistochemistry in hippocampal and prefrontal cortices. |
2020-10-01 |
2023-08-13 |
human |
| Teresa Joy, Muddanna S Rao, Sampath Madhyastha, Keshav Pa. Effect of N-Acetyl Cysteine on Intracerebroventricular Colchicine Induced Cognitive Deficits, Beta Amyloid Pathology, and Glial Cells. Neuroscience journal. vol 2019. 2020-10-01. PMID:31139638. |
colchicine has resulted in significant cognitive loss, increased intraneuronal beta amyloid protein expression, increased reactive astrocytes, and activated microglia in all the regions of the hippocampus and prefrontal cortices. |
2020-10-01 |
2023-08-13 |
human |
| Sarah J Spencer, Aniko Korosi, Sophie Layé, Barbara Shukitt-Hale, Ruth M Barriento. Food for thought: how nutrition impacts cognition and emotion. NPJ science of food. vol 1. 2020-10-01. PMID:31304249. |
low dietary intake of omega-3 polyunsaturated fatty acids can also contribute to depression through its effects on endocannabinoid and inflammatory pathways in specific brain regions leading to synaptic phagocytosis by microglia in the hippocampus, contributing to memory loss. |
2020-10-01 |
2023-08-13 |
Not clear |
| Murad-Ali Shah, Dong-Ju Park, Ju-Bin Kang, Myeong-Ok Kim, Phil-Ok Ko. Baicalin alleviates lipopolysaccharide-induced neuroglial activation and inflammatory factors activation in hippocampus of adult mice. Laboratory animal research. vol 36. 2020-10-01. PMID:32983956. |
results from the present study showed that baicalin suppresses lps-induced neuroinflammation by regulating microglia and astrocyte activation and modulating inflammatory factors in the hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Murad-Ali Shah, Dong-Ju Park, Ju-Bin Kang, Myeong-Ok Kim, Phil-Ok Ko. Baicalin alleviates lipopolysaccharide-induced neuroglial activation and inflammatory factors activation in hippocampus of adult mice. Laboratory animal research. vol 36. 2020-10-01. PMID:32983956. |
thus, these results demonstrate that baicalin has neuroprotective effect by alleviates microglia and astrocyte activation and modulates inflammatory response by suppressing nf-κb expression in hippocampus with neuroinflammation caused by lps. |
2020-10-01 |
2023-08-13 |
mouse |
| Noemi Tonna, Fabio Bianco, Michela Matteoli, Cinzia Cagnoli, Flavia Antonucci, Amedea Manfredi, Nicolò Mauro, Elisabetta Ranucci, Paolo Ferrut. A soluble biocompatible guanidine-containing polyamidoamine as promoter of primary brain cell adhesion and Science and technology of advanced materials. vol 15. issue 4. 2020-09-30. PMID:27877708. |
in this work, it was found that agma1 surface-adsorbed on cell culturing coverslips exhibits excellent properties as adhesion and proliferation promoter of primary brain cells such as microglia, as well as of hippocampal neurons and astrocytes. |
2020-09-30 |
2023-08-13 |
Not clear |
| Daniele Lana, Filippo Ugolini, Daniele Nosi, Gary L Wenk, Maria G Giovannin. Alterations in the Interplay between Neurons, Astrocytes and Microglia in the Rat Dentate Gyrus in Experimental Models of Neurodegeneration. Frontiers in aging neuroscience. vol 9. 2020-09-30. PMID:28955220. |
a diverse series of progressive modifications in the intercellular communication among neurons, astrocytes and microglia occur in the hippocampus during aging or inflammation. |
2020-09-30 |
2023-08-13 |
rat |
| Daniele Lana, Filippo Ugolini, Daniele Nosi, Gary L Wenk, Maria G Giovannin. Alterations in the Interplay between Neurons, Astrocytes and Microglia in the Rat Dentate Gyrus in Experimental Models of Neurodegeneration. Frontiers in aging neuroscience. vol 9. 2020-09-30. PMID:28955220. |
the levels of the chemokine fractalkine (cx3cl1) increased in hippocampal homogenates of aged rats and rats treated with lps, and cx3cl1 immunoreactivity colocalized with activated microglia cells. |
2020-09-30 |
2023-08-13 |
rat |
| Emily A Barton, Cassandra Baker, J Leigh Leasur. Investigation of Sex Differences in the Microglial Response to Binge Ethanol and Exercise. Brain sciences. vol 7. issue 10. 2020-09-30. PMID:29064447. |
the present study compared the number of microglia and evidence of their activation in alcohol-vulnerable regions of the brain (medial prefrontal cortex and hippocampus) in male and female rats following binge alcohol and/or exercise. |
2020-09-30 |
2023-08-13 |
rat |
| Season K Wyatt-Johnson, Seth A Herr, Amy L Brewste. Status Epilepticus Triggers Time-Dependent Alterations in Microglia Abundance and Morphological Phenotypes in the Hippocampus. Frontiers in neurology. vol 8. 2020-09-30. PMID:29326654. |
status epilepticus triggers time-dependent alterations in microglia abundance and morphological phenotypes in the hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Chin W Hui, Abygaël St-Pierre, Hassan El Hajj, Yvan Remy, Sébastien S Hébert, Giamal N Luheshi, Lalit K Srivastava, Marie-Ève Trembla. Prenatal Immune Challenge in Mice Leads to Partly Sex-Dependent Behavioral, Microglial, and Molecular Abnormalities Associated with Schizophrenia. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:29472840. |
confocal and electron microscopy revealed most pronounced differences in microglial distribution, arborization, cellular stress, and synaptic interactions in the hippocampus of male vs. female offspring exposed to poly i:c. sex differences in microglia were also measured under both steady-state and poly i:c conditions. |
2020-09-30 |
2023-08-13 |
mouse |
| Yao-Hsiang Shih, Shih-Ying Wu, Megan Yu, Sheng-Huai Huang, Chu-Wan Lee, Meei-Jyh Jiang, Pao-Yen Lin, Ting-Ting Yang, Yu-Min Ku. Hypertension Accelerates Alzheimer's Disease-Related Pathologies in Pigs and 3xTg Mice. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29615895. |
furthermore, the operation also induced shrinkage in the dendritic arbor of hippocampal dentate gyrus granule neurons, leakage in the blood-brain barrier, activation in microglia, and impairment in the hippocampus-dependent learning and memory in the 3xtg mice. |
2020-09-30 |
2023-08-13 |
mouse |
| Jia-Chen Cai, Wei Liu, Fei Lu, Wen-Bing Kong, Xin-Xuan Zhou, Peng Miao, Cheng-Xiang Lei, Yan Wan. Resveratrol attenuates neurological deficit and neuroinflammation following intracerebral hemorrhage. Experimental and therapeutic medicine. vol 15. issue 5. 2020-09-30. PMID:29725362. |
rats were sacrificed following the final behavioral test; subsequently, neuron injury and cell death in the hippocampus and microglia activation in the cortex were determined using nissl staining and ionized calcium binding adaptor molecule 1 immunofluorescence staining, respectively. |
2020-09-30 |
2023-08-13 |
rat |
| Jia-Chen Cai, Wei Liu, Fei Lu, Wen-Bing Kong, Xin-Xuan Zhou, Peng Miao, Cheng-Xiang Lei, Yan Wan. Resveratrol attenuates neurological deficit and neuroinflammation following intracerebral hemorrhage. Experimental and therapeutic medicine. vol 15. issue 5. 2020-09-30. PMID:29725362. |
furthermore, less neural damage in the hippocampus and decreased activation of microglia was observed in the ich+resv group. |
2020-09-30 |
2023-08-13 |
rat |
| Yali Chen, Mengmei Yin, Xuejin Cao, Gang Hu, Ming Xia. Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain. Aging and disease. vol 9. issue 3. 2020-09-30. PMID:29896426. |
compared with young controls, aged mice fed normal diet showed mild activation of hippocampal microglia with increased expression of cd68, a marker of the microglial m1 phenotype, and decreased expression of cd206, a marker of the microglial m2 phenotype. |
2020-09-30 |
2023-08-13 |
mouse |
| Bryon M Smith, Xinyue Yao, Kelly S Chen, Elizabeth D Kirb. A Larger Social Network Enhances Novel Object Location Memory and Reduces Hippocampal Microgliosis in Aged Mice. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29904345. |
group-housed mice did, however, show reduced numbers of iba1/cd68+ microglia in the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| Ming-Ming Tang, Wen-Juan Lin, Yu-Qin Pan, Ying-Cong L. Fibroblast Growth Factor 2 Modulates Hippocampal Microglia Activation in a Neuroinflammation Induced Model of Depression. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30135647. |
fibroblast growth factor 2 modulates hippocampal microglia activation in a neuroinflammation induced model of depression. |
2020-09-30 |
2023-08-13 |
rat |