| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kayo Terada, Jun Yamada, Yoshinori Hayashi, Zhou Wu, Yasuo Uchiyama, Christoph Peters, Hiroshi Nakanish. Involvement of cathepsin B in the processing and secretion of interleukin-1beta in chromogranin A-stimulated microglia. Glia. vol 58. issue 1. 2010-01-25. PMID:19544382. |
inconsistent with these in vitro observations, the immunoreactivity for the cleaved il-1beta was markedly observed in microglia of the hippocampus from aged wild-type but not cb-deficient mice. |
2010-01-25 |
2023-08-12 |
mouse |
| Francesca Boscia, Carla Lucia Esposito, Antonella Di Crisci, Vittorio de Franciscis, Lucio Annunziato, Laura Cerchi. GDNF selectively induces microglial activation and neuronal survival in CA1/CA3 hippocampal regions exposed to NMDA insult through Ret/ERK signalling. PloS one. vol 4. issue 8. 2010-01-19. PMID:19649251. |
collectively, this study shows that ca3 and ca1 hippocampal regions are highly responsive to gdnf-induced ret activation and neuroprotection, and suggest that, upon excitotoxicity, such neuroprotection involves a gdnf modulation of microglial cell activity. |
2010-01-19 |
2023-08-12 |
Not clear |
| Alexis Menteyne, Françoise Levavasseur, Etienne Audinat, Elena Avignon. Predominant functional expression of Kv1.3 by activated microglia of the hippocampus after Status epilepticus. PloS one. vol 4. issue 8. 2010-01-19. PMID:19707551. |
predominant functional expression of kv1.3 by activated microglia of the hippocampus after status epilepticus. |
2010-01-19 |
2023-08-12 |
Not clear |
| Alexis Menteyne, Françoise Levavasseur, Etienne Audinat, Elena Avignon. Predominant functional expression of Kv1.3 by activated microglia of the hippocampus after Status epilepticus. PloS one. vol 4. issue 8. 2010-01-19. PMID:19707551. |
we recently reported that hippocampal microglia is in a particular activation state after a status epilepticus (se) and the present study aimed at identifying which of the kv channels are functionally expressed by microglia in this model. |
2010-01-19 |
2023-08-12 |
Not clear |
| Kelly R Conner, Valerie S Payne, M Elizabeth Forbes, Mike E Robbins, David R Riddl. Effects of the AT1 receptor antagonist L-158,809 on microglia and neurogenesis after fractionated whole-brain irradiation. Radiation research. vol 173. issue 1. 2010-01-14. PMID:20041759. |
in rats examined 28 and 54 weeks after irradiation, l-158,809 treatment did not alter the effects of radiation on the number and activation of microglia in the perirhinal cortex and hippocampus, nor did it prevent the radiation-induced decrease in proliferating cells and immature neurons in the hippocampus. |
2010-01-14 |
2023-08-12 |
rat |
| Bruno P Imbimb. An update on the efficacy of non-steroidal anti-inflammatory drugs in Alzheimer's disease. Expert opinion on investigational drugs. vol 18. issue 8. 2010-01-12. PMID:19589092. |
once the abeta deposition process has started, nsaids are no longer effective and may even be detrimental because of their inhibiting activity on activated microglia of the ad brain, which mediates abeta clearance and activates compensatory hippocampal neurogenesis. |
2010-01-12 |
2023-08-12 |
human |
| Lingfei Ruan, Zhoujun Kang, Gang Pei, Yingying L. Amyloid deposition and inflammation in APPswe/PS1dE9 mouse model of Alzheimer's disease. Current Alzheimer research. vol 6. issue 6. 2010-01-05. PMID:19747158. |
cd11b-positive microglia clusters appeared in hippocampus and neocortex at 4 months of age and increased with age. |
2010-01-05 |
2023-08-12 |
mouse |
| Luna Venturi, Marco Miranda, Valentina Selmi, Luca Vitali, Alessia Tani, Martina Margheri, Angelo Raffaele De Gaudio, Chiara Adembr. Systemic sepsis exacerbates mild post-traumatic brain injury in the rat. Journal of neurotrauma. vol 26. issue 9. 2009-12-30. PMID:19257801. |
possible contributing effects of sepsis on post-traumatic outcome were evaluated as mortality rate, body weight change, neurological motor (beam balance), cognitive (morris water maze [mwm] for memory and learning) function, histopathological damage (lesion volume, cell counts in the ca1 and ca3 hippocampal areas), and morphological indices of inflammation (activated microglia and astrocytes) for the 14-day study period. |
2009-12-30 |
2023-08-12 |
rat |
| Luna Venturi, Marco Miranda, Valentina Selmi, Luca Vitali, Alessia Tani, Martina Margheri, Angelo Raffaele De Gaudio, Chiara Adembr. Systemic sepsis exacerbates mild post-traumatic brain injury in the rat. Journal of neurotrauma. vol 26. issue 9. 2009-12-30. PMID:19257801. |
the histological counterpart was represented by a cortical lesion in the area of impact at 14 days post-injury, associated with cell loss in the ca1 and ca3 hippocampal regions, and scarce infiltration of microglia. |
2009-12-30 |
2023-08-12 |
rat |
| S Rosi, V Ramirez-Amaya, A Vazdarjanova, E E Esparza, P B Larkin, J R Fike, G L Wenk, C A Barne. Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine. Brain : a journal of neurology. vol 132. issue Pt 9. 2009-12-14. PMID:19531533. |
previous data have shown that during chronic neuroinflammation the expression of the plasticity related behaviourally-induced immediate early gene arc is altered within the ca3 and the dentate gyrus; both of these hippocampal regions show a pronounced increase in activated microglia. |
2009-12-14 |
2023-08-12 |
Not clear |
| Roberta J Ward, Maria Alessandra Colivicchi, Rachel Allen, François Schol, Frédéric Lallemand, Philippe de Witte, Chiara Ballini, Laura Della Corte, David Dexte. Neuro-inflammation induced in the hippocampus of 'binge drinking' rats may be mediated by elevated extracellular glutamate content. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19765190. |
secondly, significant numbers of activated microglia were present in the dentate gyrus region of the hippocampus of the 'binge drinking' model, after major histocompatibility complex class ii staining, by comparison with the control. |
2009-12-11 |
2023-08-12 |
rat |
| Linda Jansson, Malin Wennström, Aki Johanson, Anders Tingströ. Glial cell activation in response to electroconvulsive seizures. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 7. 2009-11-17. PMID:19540297. |
ecs-induced changes in the morphology and expression of markers typical for reactive microglia, astrocytes and ng2+ glial cells were analyzed immunohistochemically in prefrontal cortex, hippocampus, amygdala, hypothalamus, piriform cortex and entorhinal cortex. |
2009-11-17 |
2023-08-12 |
rat |
| Merril Gersten, Mehrdad Alirezaei, Maria Cecilia Garibaldi Marcondes, Claudia Flynn, Timothy Ravasi, Trey Ideker, Howard S Fo. An integrated systems analysis implicates EGR1 downregulation in simian immunodeficiency virus encephalitis-induced neural dysfunction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 40. 2009-11-10. PMID:19812322. |
we show that egr1 is downregulated in siv-infected hippocampus and that it can be downregulated in differentiated human neuroblastoma cells by treatment with ccl8, a product of activated microglia. |
2009-11-10 |
2023-08-12 |
human |
| Maria Montero, Berta González, Jens Zimme. Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration. Brain research. vol 1291. 2009-11-04. PMID:19595678. |
immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration. |
2009-11-04 |
2023-08-12 |
mouse |
| Maria Montero, Berta González, Jens Zimme. Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration. Brain research. vol 1291. 2009-11-04. PMID:19595678. |
this study presents an immunotoxic method for depletion of microglia from mouse hippocampal slice cultures and the effect of this on ischemia-like oxygen-glucose deprivation (ogd). |
2009-11-04 |
2023-08-12 |
mouse |
| Maria Montero, Berta González, Jens Zimme. Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration. Brain research. vol 1291. 2009-11-04. PMID:19595678. |
based on the finding that depletion of microglia significantly increased ogd-induced ca1 pyramidal cell degeneration, we conclude that microglia at least in the initial phase of injury exert a neuroprotective role in mouse hippocampal slice cultures. |
2009-11-04 |
2023-08-12 |
mouse |
| Shinji Tanaka, Takehiro Nakamura, Kazunori Sumitani, Fumio Takahashi, Ryoji Konishi, Toshifumi Itano, Osamu Miyamot. Stage- and region-specific cyclooxygenase expression and effects of a selective COX-1 inhibitor in the mouse amygdala kindling model. Neuroscience research. vol 65. issue 1. 2009-09-03. PMID:19523994. |
cox-1 was predominant in microglia and its concentration was also enhanced in the hippocampus and areas around the third ventricle during the progression of seizures. |
2009-09-03 |
2023-08-12 |
mouse |
| Marta Olah, Gao Ping, Alexander H De Haas, Nieske Brouwer, Peter Meerlo, Eddy A Van Der Zee, Knut Biber, Hendrikus W G M Boddek. Enhanced hippocampal neurogenesis in the absence of microglia T cell interaction and microglia activation in the murine running wheel model. Glia. vol 57. issue 10. 2009-09-02. PMID:19115394. |
enhanced hippocampal neurogenesis in the absence of microglia t cell interaction and microglia activation in the murine running wheel model. |
2009-09-02 |
2023-08-12 |
mouse |
| Marta Olah, Gao Ping, Alexander H De Haas, Nieske Brouwer, Peter Meerlo, Eddy A Van Der Zee, Knut Biber, Hendrikus W G M Boddek. Enhanced hippocampal neurogenesis in the absence of microglia T cell interaction and microglia activation in the murine running wheel model. Glia. vol 57. issue 10. 2009-09-02. PMID:19115394. |
our aim was to investigate the connection between microglia activity and adult hippocampal neurogenesis under physiological conditions. |
2009-09-02 |
2023-08-12 |
mouse |
| Marta Olah, Gao Ping, Alexander H De Haas, Nieske Brouwer, Peter Meerlo, Eddy A Van Der Zee, Knut Biber, Hendrikus W G M Boddek. Enhanced hippocampal neurogenesis in the absence of microglia T cell interaction and microglia activation in the murine running wheel model. Glia. vol 57. issue 10. 2009-09-02. PMID:19115394. |
to address this question we compared the level of microglia activation in the hippocampus of mice, which had access to a running wheel for 10 days and that of sedentary controls. |
2009-09-02 |
2023-08-12 |
mouse |