| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Olah, Gao Ping, Alexander H De Haas, Nieske Brouwer, Peter Meerlo, Eddy A Van Der Zee, Knut Biber, Hendrikus W G M Boddek. Enhanced hippocampal neurogenesis in the absence of microglia T cell interaction and microglia activation in the murine running wheel model. Glia. vol 57. issue 10. 2009-09-02. PMID:19115394. |
moreover, neither t cells nor mhcii expressing microglia were present in the hippocampal brain parenchyma. |
2009-09-02 |
2023-08-12 |
mouse |
| Marta Olah, Gao Ping, Alexander H De Haas, Nieske Brouwer, Peter Meerlo, Eddy A Van Der Zee, Knut Biber, Hendrikus W G M Boddek. Enhanced hippocampal neurogenesis in the absence of microglia T cell interaction and microglia activation in the murine running wheel model. Glia. vol 57. issue 10. 2009-09-02. PMID:19115394. |
therefore, our findings suggest that classical signs of microglia activation and microglia activation arising from interaction with t cells in particular are not a prerequisite for the activity-induced increase in adult hippocampal neurogenesis in c57bl/6 mice. |
2009-09-02 |
2023-08-12 |
mouse |
| C C Leonardo, A A Hall, L A Collier, P E Gottschall, K R Pennypacke. Inhibition of gelatinase activity reduces neural injury in an ex vivo model of hypoxia-ischemia. Neuroscience. vol 160. issue 4. 2009-08-14. PMID:19272421. |
these results show that resident microglia, in the absence of peripheral immune cells, were sufficient to enhance neural injury after ogd in the organotypic hippocampal slice. |
2009-08-14 |
2023-08-12 |
rat |
| Jennifer C Palmer, Shabnam Baig, Patrick G Kehoe, Seth Lov. Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta. The American journal of pathology. vol 175. issue 1. 2009-07-15. PMID:19541930. |
immunohistochemistry with specific antibodies showed ece-2 to be abundant within pyramidal neurons in both the hippocampus and neocortex, but also to be present in certain astrocytes and microglia, particularly in ad brains. |
2009-07-15 |
2023-08-12 |
human |
| Maria Montero Domínguez, Berta González, Jens Zimme. Neuroprotective effects of the anti-inflammatory compound triflusal on ischemia-like neurodegeneration in mouse hippocampal slice cultures occur independent of microglia. Experimental neurology. vol 218. issue 1. 2009-07-07. PMID:19341733. |
neuroprotective effects of the anti-inflammatory compound triflusal on ischemia-like neurodegeneration in mouse hippocampal slice cultures occur independent of microglia. |
2009-07-07 |
2023-08-12 |
mouse |
| Eric J Downer, Thelma R Cowley, Fionnuala Cox, Francis O Maher, Vladimir Berezin, Elisabeth Bock, Marina A Lync. A synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-gamma modulation. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19457161. |
microglial cell activity increases in the rat hippocampus during normal brain aging. |
2009-06-15 |
2023-08-12 |
rat |
| Derya Sargin, Imam Hassouna, Swetlana Sperling, Anna-Leena Sirén, Hannelore Ehrenreic. Uncoupling of neurodegeneration and gliosis in a murine model of juvenile cortical lesion. Glia. vol 57. issue 7. 2009-06-08. PMID:18985736. |
here we show, based on comprehensive stereological analysis, that early unilateral lesion causes immediate and lasting bilateral increase in the number of microglia in cingulate cortex and hippocampus, consistent with a chronic low-grade inflammatory process. |
2009-06-08 |
2023-08-12 |
mouse |
| L Holtman, E A van Vliet, R van Schaik, C M Queiroz, E Aronica, J A Gorte. Effects of SC58236, a selective COX-2 inhibitor, on epileptogenesis and spontaneous seizures in a rat model for temporal lobe epilepsy. Epilepsy research. vol 84. issue 1. 2009-05-22. PMID:19186029. |
sc58236 effectively reduced pge(2) production but did not modify seizure development or the extent of cell death or microglia activation in the hippocampus. |
2009-05-22 |
2023-08-12 |
rat |
| C T Ekdahl, Z Kokaia, O Lindval. Brain inflammation and adult neurogenesis: the dual role of microglia. Neuroscience. vol 158. issue 3. 2009-05-08. PMID:18662748. |
in the initial studies in rodents, brain inflammation and microglia activation were found to be detrimental for the survival of the new hippocampal neurons early after they had been born. |
2009-05-08 |
2023-08-12 |
Not clear |
| Chuanhai Cao, Gary W Arendash, Alexander Dickson, Malgorzata B Mamcarz, Xiaoyang Lin, Douglas W Ethel. Abeta-specific Th2 cells provide cognitive and pathological benefits to Alzheimer's mice without infiltrating the CNS. Neurobiology of disease. vol 34. issue 1. 2009-05-05. PMID:19167499. |
pathological analysis of the hippocampus revealed a 30% decrease of plaque-associated microglia and less vascular amyloidosis in t cell treated mice. |
2009-05-05 |
2023-08-12 |
mouse |
| Hidetoshi Akimoto, Hyuck Joon Kwon, Michitaka Ozaki, Kazunori Yasuda, Ken-ichi Honma, Yoshihiro Ohmiy. In vivo bioluminescence imaging of bone marrow-derived cells in brain inflammation. Biochemical and biophysical research communications. vol 380. issue 4. 2009-04-28. PMID:19338764. |
immunohistochemical investigation demonstrated an increase in the infiltration of bone marrow cells into the hippocampus because of the lps injection and differentiation of the infiltrated cells into microglia, but not into neurons or astrocytes. |
2009-04-28 |
2023-08-12 |
mouse |
| Mastura Monif, Christopher A Reid, Kim L Powell, Megan L Smart, David A William. The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 12. 2009-04-21. PMID:19321774. |
we report that overexpression alone of a purinergic p2x(7)r, in the absence of pathological insults, is sufficient to drive the activation and proliferation of microglia in rat primary hippocampal cultures. |
2009-04-21 |
2023-08-12 |
rat |
| Mastura Monif, Christopher A Reid, Kim L Powell, Megan L Smart, David A William. The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 12. 2009-04-21. PMID:19321774. |
oxatp treatment of primary hippocampal cultures expressing exogenous p2x(7)rs resulted in a significant decrease in the number of activated microglia. |
2009-04-21 |
2023-08-12 |
rat |
| Jae K Ryu, Taesup Cho, Hyun B Choi, Yu Tian Wang, James G McLarno. Microglial VEGF receptor response is an integral chemotactic component in Alzheimer's disease pathology. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 1. 2009-04-08. PMID:19129379. |
expression of flt-1 was significantly increased in tissue obtained from ad patients [compared with tissue from nondemented (nd) individuals], in abeta(1-42)-injected rat hippocampus, and in peptide-stimulated human microglia. |
2009-04-08 |
2023-08-12 |
human |
| Choong Hyun Lee, In Koo Hwang, In Se Lee, Ki-Yeon Yoo, Jung Hoon Choi, Bong-Hee Lee, Moo-Ho Wo. Differential immunoreactivity of microglial and astrocytic marker protein in the hippocampus of the seizure resistant and sensitive gerbils. The Journal of veterinary medical science. vol 70. issue 12. 2009-04-07. PMID:19122416. |
in the present study, we compared differences in ionized calcium-binding adapter molecule 1 (iba-1) and glial fibrillary acidic protein (gfap) immunoreactivities for microglia and astrocytes, respectively, in the hippocampus of the seizure-resistant (sr) and seizure-sensitive (ss) gerbils. |
2009-04-07 |
2023-08-12 |
Not clear |
| Sriram Ramanan, Mitra Kooshki, Weiling Zhao, Fang-Chi Hsu, Mike E Robbin. PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways. Free radical biology & medicine. vol 45. issue 12. 2009-02-23. PMID:18852043. |
studies on rodents have shown a rapid and sustained increase in activated microglia (brain macrophages) following brain irradiation, contributing to a chronic inflammatory response and a corresponding decrease in hippocampal neurogenesis. |
2009-02-23 |
2023-08-12 |
Not clear |
| Marcin Rylski, Renata Amborska, Katarzyna Zybura, Filip A Konopacki, Grzegorz M Wilczynski, Leszek Kaczmare. Yin Yang 1 expression in the adult rodent brain. Neurochemical research. vol 33. issue 12. 2009-02-19. PMID:18584324. |
in the rat hippocampus, yy1 protein and mrna are very strongly expressed in neurons, and to a lesser extent in oligodendroglia and microglia. |
2009-02-19 |
2023-08-12 |
rat |
| Emiliano Tesoro Cruz, Iris Angélica Feria Romero, Juan Gabriel López Mendoza, Sandra Orozco Suárez, Rafael Hernández González, Francisco Blanco Favela, Armando Pérez Torres, José Alvaro Aguilar Setié. Efficient post-exposure prophylaxis against rabies by applying a four-dose DNA vaccine intranasally. Vaccine. vol 26. issue 52. 2009-02-19. PMID:18940223. |
the expression of g protein was detected in the nalt, cerebellum, cerebral cortex (neocortex), cerebellum and hippocampus, mainly in the glial cells (microglia) and microvessels. |
2009-02-19 |
2023-08-12 |
mouse |
| Christopher J Yuskaitis, Richard S Jop. Glycogen synthase kinase-3 regulates microglial migration, inflammation, and inflammation-induced neurotoxicity. Cellular signalling. vol 21. issue 2. 2009-02-10. PMID:19007880. |
regulation of microglia functions were also evident in cultured mouse hippocampal slices where gsk3 inhibitors reduced cytokine production and microglial migration, and provided protection from inflammation-induced neuronal toxicity. |
2009-02-10 |
2023-08-12 |
mouse |
| Michaela Fux, Nico van Rooijen, Trevor Owen. Macrophage-independent T cell infiltration to the site of injury-induced brain inflammation. Journal of neuroimmunology. vol 203. issue 1. 2009-02-02. PMID:18653241. |
there was a slight delay in the expansion of cd45(dim) cd11+ microglia in clodronate-liposome treated mice, but macrophage depletion had no effect on the percentage of infiltrating t cells in the lesion-reactive hippocampus. |
2009-02-02 |
2023-08-12 |
mouse |