| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Wu, Aitao Wang, Zhe Min, Yongjie Xiong, Qiuyue Yan, Jinping Zhang, Jie Xu, Suming Zhan. Lipoxin A4 inhibits the production of proinflammatory cytokines induced by β-amyloid in vitro and in vivo. Biochemical and biophysical research communications. vol 408. issue 3. 2011-07-26. PMID:21501589. |
in this study, we investigated the inhibitory effect and the molecular mechanism of the lipoxin a(4) (lxa(4)) on the production of interleukin-1β (il-1β) and tumor necrosis factorα (tnfα) induced by β-amyloid in the cortex and hippocampus of mice, and in aβ-stimulated bv2 cells, a mouse microglial cell line. |
2011-07-26 |
2023-08-12 |
mouse |
| Kathryn J Bryan, Xiongwei Zhu, Peggy L Harris, George Perry, Rudy J Castellani, Mark A Smith, Gemma Casadesu. Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease. Molecular neurodegeneration. vol 3. 2011-07-14. PMID:18786268. |
mhc class ii molecules are found in microglia of the brain, while mif is found in both microglia and neurons of the hypothalamus, hippocampus, and cortex. |
2011-07-14 |
2023-08-12 |
Not clear |
| Hiroaki Nakahara, Yoshihiro Konishi, Thomas G Beach, Naoto Yamada, Satoshi Makino, Ikuo Tooyam. Infiltration of T lymphocytes and expression of icam-1 in the hippocampus of patients with hippocampal sclerosis. Acta histochemica et cytochemica. vol 43. issue 6. 2011-07-14. PMID:21245982. |
we and others have previously shown that reactive microglia express the major histocompatibility complex (mhc) class i and class ii antigens in the hippocampus of patients suffering from epilepsy. |
2011-07-14 |
2023-08-12 |
human |
| Jan Mulder, Misha Zilberter, Susana J Pasquaré, Alán Alpár, Gunnar Schulte, Samira G Ferreira, Attila Köfalvi, Ana M Martín-Moreno, Erik Keimpema, Heikki Tanila, Masahiko Watanabe, Ken Mackie, Tibor Hortobágyi, Maria L de Ceballos, Tibor Harkan. Molecular reorganization of endocannabinoid signalling in Alzheimer's disease. Brain : a journal of neurology. vol 134. issue Pt 4. 2011-07-01. PMID:21459826. |
hippocampal protein concentrations for the sn-1-diacylglycerol lipase α and β isoforms, synthesizing 2-arachidonoyl glycerol, significantly increased in definite alzheimer's (braak stage vi), with ectopic sn-1-diacylglycerol lipase β expression found in microglia accumulating near senile plaques and apposing cb(1) cannabinoid receptor-positive presynapses. |
2011-07-01 |
2023-08-12 |
mouse |
| Eric S Wohleb, Mark L Hanke, Angela W Corona, Nicole D Powell, La'Tonia M Stiner, Michael T Bailey, Randy J Nelson, Jonathan P Godbout, John F Sherida. β-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 17. 2011-06-24. PMID:21525267. |
repeated social defeat also increased the presence of deramified microglia in the medial amygdala, prefrontal cortex, and hippocampus. |
2011-06-24 |
2023-08-12 |
mouse |
| Michela Zattoni, Maria Luisa Mura, Francine Deprez, Reto A Schwendener, Britta Engelhardt, Karl Frei, Jean-Marc Fritsch. Brain infiltration of leukocytes contributes to the pathophysiology of temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411646. |
blood-brain barrier disruption and neurodegeneration in the kainate-lesioned hippocampus were accompanied by sustained icam-1 upregulation, microglial cell activation, and infiltration of cd3(+) t-cells. |
2011-06-15 |
2023-08-12 |
mouse |
| Juan A Orellana, Kenji F Shoji, Verónica Abudara, Pascal Ezan, Edwige Amigou, Pablo J Sáez, Jean X Jiang, Christian C Naus, Juan C Sáez, Christian Giaum. Amyloid β-induced death in neurons involves glial and neuronal hemichannels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 13. 2011-05-30. PMID:21451035. |
microglia, astrocytes, or neuronal cultures as well as acute hippocampal slices made from gfap-egfp transgenic mice were treated with the active fragment of aβ. |
2011-05-30 |
2023-08-12 |
mouse |
| Heidi M Mitchell, David M White, Miriam S Domowicz, Richard P Krai. Cold pre-conditioning neuroprotection depends on TNF-α and is enhanced by blockade of interleukin-11. Journal of neurochemistry. vol 117. issue 2. 2011-05-27. PMID:21070241. |
also, as slice cultures closely approximate their in vivo counterpart and include quiescent microglia, we used rat hippocampal slice cultures to confirm this hypothesis. |
2011-05-27 |
2023-08-12 |
rat |
| Un-In Wu, Fu-Der Mai, Ji-Nan Sheu, Li-You Chen, Yu-Ting Liu, Hai-Cheng Huang, Hung-Ming Chan. Melatonin inhibits microglial activation, reduces pro-inflammatory cytokine levels, and rescues hippocampal neurons of adult rats with acute Klebsiella pneumoniae meningitis. Journal of pineal research. vol 50. issue 2. 2011-05-26. PMID:21062353. |
results indicate that in k. pneumoniae-infected rats, numerous calcium-enriched microglia, enhanced pro-inflammatory cytokine, and various apoptotic neurons with low bio-energetic activity were detected in hippocampus. |
2011-05-26 |
2023-08-12 |
rat |
| Nelson Rebola, Ana Patrícia Simões, Paula M Canas, Angelo R Tomé, Geanne M Andrade, Claire E Barry, Paula M Agostinho, Marina A Lynch, Rodrigo A Cunh. Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction. Journal of neurochemistry. vol 117. issue 1. 2011-05-16. PMID:21235574. |
thus, we tested if the intracerebroventricular injection of a selective a2ar antagonist (sch58261) would attenuate the changes in the hippocampus triggered by intraperitoneal administration of lipopolysaccharide (lps) that induces neuroinflammation through microglia activation. |
2011-05-16 |
2023-08-12 |
rat |
| Sanae Hasegawa-Ishii, Shiro Takei, Yoichi Chiba, Ayako Furukawa, Hiroyuki Umegaki, Akihisa Iguchi, Noriko Kawamura, Keisuke Yoshikawa, Masanori Hosokawa, Atsuyoshi Shimad. Morphological impairments in microglia precede age-related neuronal degeneration in senescence-accelerated mice. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 1. 2011-05-03. PMID:20497341. |
hippocampal sections prepared from 3-, 8- and 14-month-old samp10 and 3-, 8-, 14- and 24-month-old samr1 mice were stained immunohistochemically with anti-iba-1 antibody to highlight microglia. |
2011-05-03 |
2023-08-12 |
mouse |
| Elena Pompili, Cinzia Fabrizi, Stefania Lucia Nori, Barbara Panetta, Maria Concetta Geloso, Valentina Corvino, Fabrizio Michetti, Lorenzo Fumagall. Protease-activated receptor-1 expression in rat microglia after trimethyltin treatment. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 59. issue 3. 2011-04-25. PMID:21378284. |
tmt is an organotin compound that induces severe hippocampal neurodegeneration associated with astrocyte and microglia activation. |
2011-04-25 |
2023-08-12 |
rat |
| Michael Mattocks, Vincent Tropep. Waste management and adult neurogenesis. Cell stem cell. vol 7. issue 4. 2011-03-16. PMID:20887944. |
(2010) show that unactivated microglia assume the role of waste managers to eliminate cellular debris from apoptosing newborn cells in the hippocampus. |
2011-03-16 |
2023-08-12 |
Not clear |
| Amanda Sierra, Juan M Encinas, Juan J P Deudero, Jessica H Chancey, Grigori Enikolopov, Linda S Overstreet-Wadiche, Stella E Tsirka, Mirjana Maletic-Savati. Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell stem cell. vol 7. issue 4. 2011-03-16. PMID:20887954. |
microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. |
2011-03-16 |
2023-08-12 |
Not clear |
| Gil-Saeng Jeong, Bin Li, Dong-Sung Lee, Ki Hyun Kim, Il Kyun Lee, Kang Ro Lee, Youn-Chul Ki. Cytoprotective and anti-inflammatory effects of spinasterol via the induction of heme oxygenase-1 in murine hippocampal and microglial cell lines. International immunopharmacology. vol 10. issue 12. 2011-03-15. PMID:20933625. |
cytoprotective and anti-inflammatory effects of spinasterol via the induction of heme oxygenase-1 in murine hippocampal and microglial cell lines. |
2011-03-15 |
2023-08-12 |
Not clear |
| Gil-Saeng Jeong, Bin Li, Dong-Sung Lee, Ki Hyun Kim, Il Kyun Lee, Kang Ro Lee, Youn-Chul Ki. Cytoprotective and anti-inflammatory effects of spinasterol via the induction of heme oxygenase-1 in murine hippocampal and microglial cell lines. International immunopharmacology. vol 10. issue 12. 2011-03-15. PMID:20933625. |
in this study, we report the efficacy of spinasterol in effectively modulating the regulation of antioxidative and anti-inflammatory activity through the upregulation of heme oxygenase (ho)-1 in murine hippocampal ht22 cells and bv2 microglia. |
2011-03-15 |
2023-08-12 |
Not clear |
| A M Espinosa-Oliva, R M de Pablos, R F Villarán, S Argüelles, J L Venero, A Machado, J Can. Stress is critical for LPS-induced activation of microglia and damage in the rat hippocampus. Neurobiology of aging. vol 32. issue 1. 2011-03-14. PMID:19286276. |
stress is critical for lps-induced activation of microglia and damage in the rat hippocampus. |
2011-03-14 |
2023-08-12 |
rat |
| Sanae Hasegawa-Ishii, Shiro Takei, Muneo Inaba, Hiroyuki Umegaki, Yoichi Chiba, Ayako Furukawa, Noriko Kawamura, Masanori Hosokawa, Atsuyoshi Shimad. Defects in cytokine-mediated neuroprotective glial responses to excitotoxic hippocampal injury in senescence-accelerated mouse. Brain, behavior, and immunity. vol 25. issue 1. 2011-03-10. PMID:20804842. |
results indicated well-orchestrated cytokine-mediated glial interactions in the injured hippocampus of samr1 mice, in which microglia-derived interferon (ifn)-γ stimulated astrocytes via ifn-γ receptor and thereby induced expression of cxcl10 and macrophage inflammatory protein (mip)-1α, and activated microglia produced granulocyte-macrophage colony-stimulating factor (gm-csf) and osteopontin (opn). |
2011-03-10 |
2023-08-12 |
mouse |
| Ryan D Readnower, Mikulas Chavko, Saleena Adeeb, Michael D Conroy, James R Pauly, Richard M McCarron, Patrick G Sulliva. Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury. Journal of neuroscience research. vol 88. issue 16. 2011-03-03. PMID:20882564. |
by using antibodies against cd11b/c, microglia morphology characteristic of activated microglia was observed in the hippocampus and substantia nigra of animals exposed to blast. |
2011-03-03 |
2023-08-12 |
rat |
| Ulrika Björklund, Mikael Persson, Lars Rönnbäck, Elisabeth Hansso. Primary cultures from cerebral cortex and hippocampus enriched in glutamatergic and GABAergic neurons. Neurochemical research. vol 35. issue 11. 2011-02-03. PMID:20680458. |
we found that these primary neuron enriched cultures from either newborn rat cerebral cortex or hippocampus contain small gabaergic and large glutamatergic neurons as well as astrocytes and microglia. |
2011-02-03 |
2023-08-12 |
rat |