All Relations between hypertrophic and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Liming Bian, David Y Zhai, Emily C Zhang, Robert L Mauck, Jason A Burdic. Dynamic compressive loading enhances cartilage matrix synthesis and distribution and suppresses hypertrophy in hMSC-laden hyaluronic acid hydrogels. Tissue engineering. Part A. vol 18. issue 7-8. 2012-07-23. PMID:21988555. in this study we investigated the effect of dynamic compressive loading on chondrogenesis, the production and distribution of cartilage specific matrix, and the hypertrophic differentiation of human mscs encapsulated in hyaluronic acid (ha) hydrogels during long term culture. 2012-07-23 2023-08-12 human
Alexandra V Finsen, Ida G Lunde, Ivar Sjaastad, Even K Østli, Marianne Lyngra, Hilde O Jarstadmarken, Almira Hasic, Ståle Nygård, Sarah A Wilcox-Adelman, Paul F Goetinck, Torstein Lyberg, Biljana Skrbic, Geir Florholmen, Theis Tønnessen, William E Louch, Srdjan Djurovic, Cathrine R Carlson, Geir Christense. Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway. PloS one. vol 6. issue 12. 2012-07-20. PMID:22164265. we have investigated the hypothesis that the transmembrane z-disc proteoglycan syndecan-4, a co-receptor for integrins, connecting extracellular matrix proteins to the cytoskeleton, is an important signal transducer in cardiomyocytes during development of concentric myocardial hypertrophy following pressure overload. 2012-07-20 2023-08-12 mouse
Shaoping Xu, Amy S Shriver, Dammanahalli K Jagadeesha, Ali H Chamseddine, Katalin Szőcs, Neal L Weintraub, Kathy K Griendling, Ramesh C Bhalla, Francis J Mille. Increased expression of Nox1 in neointimal smooth muscle cells promotes activation of matrix metalloproteinase-9. Journal of vascular research. vol 49. issue 3. 2012-07-19. PMID:22433789. vascular injury causes neointimal hypertrophy, which is characterized by redox-mediated matrix degradation and smooth muscle cell (smc) migration and proliferation. 2012-07-19 2023-08-12 Not clear
Hanna E Abbou. Mesangial cell biology. Experimental cell research. vol 318. issue 9. 2012-07-13. PMID:22414873. in response to metabolic, immunologic or hemodynamic injury, these cells undergo apoptosis or acquire an activated phenotype and undergo hypertrophy, proliferation with excessive production of matrix proteins, growth factors, chemokines and cytokines. 2012-07-13 2023-08-12 Not clear
Mitsuo Kato, Jung Tak Park, Rama Nataraja. MicroRNAs and the glomerulus. Experimental cell research. vol 318. issue 9. 2012-07-13. PMID:22421514. increased expansion (hypertrophy) and accumulation of extracellular matrix (ecm) proteins such as collagen (fibrosis) in the glomerular mesangium along with glomerular podocyte dysfunction are major features of dn. 2012-07-13 2023-08-12 human
John P Burand, Woojin Kim, Claudio L Afonso, Edan R Tulman, Gerald F Kutish, Zhiqiang Lu, Daniel L Roc. Analysis of the genome of the sexually transmitted insect virus Helicoverpa zea nudivirus 2. Viruses. vol 4. issue 1. 2012-07-10. PMID:22355451. these included a presumed juvenile hormone esterase gene, a gene coding for a putative zinc-dependent matrix metalloprotease, and a major facilitator superfamily protein gene; all of which are believed to play a role in the cellular proliferation and the tissue hypertrophy observed in the malformation of reproductive organs observed in hznv-2 infected corn earworm moths, helicoverpa zea. 2012-07-10 2023-08-12 Not clear
Rusella Mirza, Shanlou Qiao, Keisuke Tateyama, Takeshi Miyamoto, Lu Xiuli, Hisao Se. 3β-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species. Journal of bone and mineral metabolism. vol 30. issue 2. 2012-07-03. PMID:21845517. hypertrophic differentiation was evidenced by higher expression of indian hedgehog, alkaline phosphatase, and matrix metalloproteinase 13. 2012-07-03 2023-08-12 mouse
Stav Simsa-Maziel, Efrat Monsonego-Orna. Interleukin-1β promotes proliferation and inhibits differentiation of chondrocytes through a mechanism involving down-regulation of FGFR-3 and p21. Endocrinology. vol 153. issue 5. 2012-06-29. PMID:22492305. here we show that il-1β affects bone growth by directly disturbing the normal sequence of events in the growth plate, resulting in increased proliferation and widening of the proliferative zone, whereas the hypertrophic zone becomes disorganized, with impaired matrix structure and increased apoptosis and osteoclast activity. 2012-06-29 2023-08-12 Not clear
Lanyu Zhang, Shanshan Pang, Bo Deng, Lihua Qian, Juan Chen, Junjie Zou, Jiaoyang Zheng, Linghui Yang, Chunyang Zhang, Xiangfang Chen, Zhimin Liu, Yingying L. High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol. The international journal of biochemistry & cell biology. vol 44. issue 4. 2012-06-15. PMID:22245600. renal hypertrophy and extracellular matrix accumulation are early features of diabetic nephropathy. 2012-06-15 2023-08-12 rat
Donghong Fang, Hongyu Guan, Juan Liu, Guohong Wei, Weijian Ke, Bin Yao, Haipeng Xiao, Yanbing L. Early intensive insulin therapy attenuates the p38 pathway in the renal cortex and indices of nephropathy in diabetic rats. Endocrine journal. vol 59. issue 1. 2012-06-04. PMID:22068113. glomerular hypertrophy and mesangial matrix expansion were prominent in the 16wdm and li groups while the ei groups remained normal and similar to the 16wnc group. 2012-06-04 2023-08-12 rat
Donghong Fang, Hongyu Guan, Juan Liu, Guohong Wei, Weijian Ke, Bin Yao, Haipeng Xiao, Yanbing L. Early intensive insulin therapy attenuates the p38 pathway in the renal cortex and indices of nephropathy in diabetic rats. Endocrine journal. vol 59. issue 1. 2012-06-04. PMID:22068113. however, late insulin therapy did not abrogate the increased renal cortical p38 mapk pathway activation in diabetic rats and led to glomerular hypertrophy and extracellular matrix expansion. 2012-06-04 2023-08-12 rat
Franck Simon, Daniele Bergeron, Sébastien Larochelle, Carlos A Lopez-Vallé, Hervé Genest, Alexis Armour, Véronique J Mouli. Enhanced secretion of TIMP-1 by human hypertrophic scar keratinocytes could contribute to fibrosis. Burns : journal of the International Society for Burn Injuries. vol 38. issue 3. 2012-05-23. PMID:22040932. hypertrophic scars are a pathological process characterized by an excessive deposition of extracellular matrix components. 2012-05-23 2023-08-12 human
Franck Simon, Daniele Bergeron, Sébastien Larochelle, Carlos A Lopez-Vallé, Hervé Genest, Alexis Armour, Véronique J Mouli. Enhanced secretion of TIMP-1 by human hypertrophic scar keratinocytes could contribute to fibrosis. Burns : journal of the International Society for Burn Injuries. vol 38. issue 3. 2012-05-23. PMID:22040932. the dermal matrix of these rhs was recreated using mesenchymal cells from three different origins (skin, wound and hypertrophic scar). 2012-05-23 2023-08-12 human
Dutmanee Seriwatanachai, Nateetip Krishnamra, Narattaphol Charoenphandh. Chondroregulatory action of prolactin on proliferation and differentiation of mouse chondrogenic ATDC5 cells in 3-dimensional micromass cultures. Biochemical and biophysical research communications. vol 420. issue 1. 2012-05-16. PMID:22405773. a recent investigation in lactating rats has provided evidence that the lactogenic hormone prolactin (prl) increases endochondral bone growth and bone elongation, presumably by accelerating apoptosis of hypertrophic chondrocytes in the growth plate and/or subsequent chondrogenic matrix mineralization. 2012-05-16 2023-08-12 mouse
Saurabh Dahiya, Shephali Bhatnagar, Sajedah M Hindi, Chunhui Jiang, Pradyut K Paul, Shihuan Kuang, Ashok Kuma. Elevated levels of active matrix metalloproteinase-9 cause hypertrophy in skeletal muscle of normal and dystrophin-deficient mdx mice. Human molecular genetics. vol 20. issue 22. 2012-05-15. PMID:21846793. elevated levels of active matrix metalloproteinase-9 cause hypertrophy in skeletal muscle of normal and dystrophin-deficient mdx mice. 2012-05-15 2023-08-12 mouse
G P Sidgwick, A Baya. Extracellular matrix molecules implicated in hypertrophic and keloid scarring. Journal of the European Academy of Dermatology and Venereology : JEADV. vol 26. issue 2. 2012-05-14. PMID:21838832. extracellular matrix molecules implicated in hypertrophic and keloid scarring. 2012-05-14 2023-08-12 Not clear
Norio Amizuka, Tomoka Hasegawa, Kimimitsu Oda, Paulo Henrique Luiz de Freitas, Kazuto Hoshi, Minqi Li, Hidehiro Ozaw. Histology of epiphyseal cartilage calcification and endochondral ossification. Frontiers in bioscience (Elite edition). vol 4. 2012-05-14. PMID:22202021. cartilage calcification is carried out by chondrocytes as they hypertrophy and begin to secrete matrix vesicles. 2012-05-14 2023-08-12 Not clear
Norio Amizuka, Tomoka Hasegawa, Kimimitsu Oda, Paulo Henrique Luiz de Freitas, Kazuto Hoshi, Minqi Li, Hidehiro Ozaw. Histology of epiphyseal cartilage calcification and endochondral ossification. Frontiers in bioscience (Elite edition). vol 4. 2012-05-14. PMID:22202021. hypertrophic chondrocytes secrete vesicles in the cartilaginous matrix of intercolumnar septae only, forming well-calcified longitudinal septae and poorly-calcified transverse partitions. 2012-05-14 2023-08-12 Not clear
P S Skagen, T Horn, H A Kruse, B Staergaard, M M Rapport, T Nicolaise. Osteochondritis dissecans (OCD), an endoplasmic reticulum storage disease?: a morphological and molecular study of OCD fragments. Scandinavian journal of medicine & science in sports. vol 21. issue 6. 2012-05-01. PMID:20561273. further, von kossa staining and tem showed empty lacunae close to mineralized "islands" in the cartilage and hypertrophic chondrocytes containing accumulated matrix proteins. 2012-05-01 2023-08-12 Not clear
Geert W Schmid-Schönbei. An emerging role of degrading proteinases in hypertension and the metabolic syndrome: autodigestion and receptor cleavage. Current hypertension reports. vol 14. issue 1. 2012-05-01. PMID:22081429. an emerging body of evidence suggests that human and experimental hypertensives may exhibit uncontrolled activity of proteinases, including the family of matrix metalloproteinases, recognized for their ability to restructure the extracellular matrix proteins and to play a role in hypertrophy. 2012-05-01 2023-08-12 human