| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Annette Schröder, Tyler P Kirwan, Jia-Xin Jiang, Karen J Aitken, Darius J Bägl. Rapamycin attenuates bladder hypertrophy during long-term outlet obstruction in vivo: tissue, matrix and mechanistic insights. The Journal of urology. vol 189. issue 6. 2013-07-17. PMID:23313213. |
rapamycin attenuates bladder hypertrophy during long-term outlet obstruction in vivo: tissue, matrix and mechanistic insights. |
2013-07-17 |
2023-08-12 |
rat |
| Shunichi Shimizu, Masaaki Ishibashi, Sumito Kumagai, Teruaki Wajima, Toshihito Hiroi, Tatsuya Kurihara, Masakazu Ishii, Yuji Kiuch. Decreased cardiac mitochondrial tetrahydrobiopterin in a rat model of pressure overload. International journal of molecular medicine. vol 31. issue 3. 2013-07-10. PMID:23313998. |
moreover, continuous administration of bh4 to rats with pressure overload increased mitochondrial bh4 levels and reduced cardiac fibrosis and matrix metallopeptidase activity, but not cardiac hypertrophy. |
2013-07-10 |
2023-08-12 |
rat |
| Kurt D Marshall, Brittany N Muller, Maike Krenz, Laurin M Hanft, Kerry S McDonald, Kevin C Dellsperger, Craig A Emte. Heart failure with preserved ejection fraction: chronic low-intensity interval exercise training preserves myocardial O2 balance and diastolic function. Journal of applied physiology (Bethesda, Md. : 1985). vol 114. issue 1. 2013-07-08. PMID:23104696. |
in conclusion, chronic low-intensity interval exercise training attenuates diastolic impairment by promoting compliant extracellular matrix fibrotic components and preserving extracellular matrix regulatory mechanisms, preserves myocardial oxygen balance, and promotes a physiological molecular hypertrophic signaling phenotype in a large animal model resembling heart failure with preserved ejection fraction. |
2013-07-08 |
2023-08-12 |
Not clear |
| Ana Paula Nadu, Anderson J Ferreira, Timothy L Reudelhuber, Michael Bader, Robson A S Santo. Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1-7)3292 rats. Journal of the American Society of Hypertension : JASH. vol 2. issue 5. 2013-07-04. PMID:20409916. |
we investigated the expression of specific extracellular matrix (ecm) proteins in cardiac hypertrophy induced by isoproterenol in tgr(a1-7)3292 rats. |
2013-07-04 |
2023-08-12 |
rat |
| Costas Tsioufis, Ioannis Bafakis, Alexandros Kasiakogias, Christodoulos Stefanadi. The role of matrix metalloproteinases in diabetes mellitus. Current topics in medicinal chemistry. vol 12. issue 10. 2013-07-03. PMID:22519446. |
in diabetic nephropathy, altered mmps expression contributes to extracellular matrix deposition and glomerular hypertrophy that eventually lead to proteinuria and renal insufficiency. |
2013-07-03 |
2023-08-12 |
Not clear |
| Qian Zhang, Kai Tao, Wei Huang, Yaguang Tian, Xiaoyan Li. Elevated expression of pleiotrophin in human hypertrophic scars. Journal of molecular histology. vol 44. issue 1. 2013-06-17. PMID:23054143. |
hypertrophic scar (hs) is a cutaneous fibrotic disorder characterized by persistent inflammation, excessive proliferation of fibroblasts, and abundant accumulation of extracellular matrix (ecm) proteins. |
2013-06-17 |
2023-08-12 |
human |
| Yi Cai, Shan-Shan Yu, Ting-Ting Chen, Si Gao, Biao Geng, Yang Yu, Jian-Tao Ye, Pei-Qing Li. EGCG inhibits CTGF expression via blocking NF-κB activation in cardiac fibroblast. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 20. issue 2. 2013-06-10. PMID:23141425. |
in heart, inappropriate increase in level of ctgf promotes fibroblast proliferation and extracellular matrix (ecm) accumulation, thereby exacerbating cardiac hypertrophy and subsequent failure. |
2013-06-10 |
2023-08-12 |
rat |
| Fırat Seyfettinoğlu, Özgür Sünneli, Ali Dülgeroğlu, Osman Arslan Bor. A case of ingrown toenail accompanied by extreme soft tissue hypertrophy to the extent of invisible nail. Acta orthopaedica et traumatologica turcica. vol 46. issue 5. 2013-06-06. PMID:23268828. |
we present hypertrophic tissue excision and bilateral partial matrix excision in an unclassified case of ingrown toenail in which the bilateral side wall hypertrophy covered the entire nail; normal tissue of the nail was invisible, along with first year follow-up results. |
2013-06-06 |
2023-08-12 |
Not clear |
| Elizabeth W Bradley, Lomeli R Carpio, Jennifer J Westendor. Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion. The Journal of biological chemistry. vol 288. issue 14. 2013-05-31. PMID:23408427. |
these phenotypes led to the hypothesis that the akt/mtor pathway was repressed in these hdac3-deficient chondrocytes because akt promotes hypertrophy and matrix production in many tissues. |
2013-05-31 |
2023-08-12 |
mouse |
| Elizabeth W Bradley, Lomeli R Carpio, Jennifer J Westendor. Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion. The Journal of biological chemistry. vol 288. issue 14. 2013-05-31. PMID:23408427. |
these data demonstrate that hdac3 controls chondrocyte hypertrophy and matrix content by repressing phlpp1 expression and facilitating akt activity. |
2013-05-31 |
2023-08-12 |
mouse |
| Kumar Kotlo, Keven R Johnson, Jean M Grillon, David L Geenen, Pieter deTombe, Robert S Danzige. Phosphoprotein abundance changes in hypertensive cardiac remodeling. Journal of proteomics. vol 77. 2013-05-23. PMID:22659219. |
a total of 25 common phosphoproteins with differences in abundance in (1) the 3 hypertrophic and/or (2) the 2 systolic failure heart models were identified (ci>99%) by matrix assisted laser desorption ionization mass spectrometry (maldi-ms) and mascot analysis. |
2013-05-23 |
2023-08-12 |
rat |
| Qian Zhang, Xinhua Xiao, Ming Li, Wenhui Li, Miao Yu, Huabing Zhang, Xiaofang Sun, Lili Mao, Hongding Xian. Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model. Journal of natural medicines. vol 67. issue 1. 2013-05-22. PMID:22434410. |
kidney hypertrophy and glomerular mesangial matrix expansion were also ameliorated. |
2013-05-22 |
2023-08-12 |
rat |
| David Jj Saliken, Aillette Mulet-Sierra, Nadr M Jomha, Adetola B Adesid. Decreased hypertrophic differentiation accompanies enhanced matrix formation in co-cultures of outer meniscus cells with bone marrow mesenchymal stromal cells. Arthritis research & therapy. vol 14. issue 3. 2013-05-22. PMID:22726892. |
decreased hypertrophic differentiation accompanies enhanced matrix formation in co-cultures of outer meniscus cells with bone marrow mesenchymal stromal cells. |
2013-05-22 |
2023-08-12 |
Not clear |
| Jan Menne, Nelli Shushakova, Janina Bartels, Yulia Kiyan, Robert Laudeley, Hermann Haller, Joon-Keun Park, Matthias Meie. Dual inhibition of classical protein kinase C-α and protein kinase C-β isoforms protects against experimental murine diabetic nephropathy. Diabetes. vol 62. issue 4. 2013-05-21. PMID:23434935. |
after 8 weeks of diabetes mellitus, the high-glucose-induced renal and glomerular hypertrophy as well as transforming growth factor-β1) and extracellular matrix production were diminished in the pkc-α/β(-/-) mice compared with wild-type controls. |
2013-05-21 |
2023-08-12 |
mouse |
| Joanna Karbowska, Zdzisław Kocha. [Leptin as a mediator between obesity and cardiac dysfunction]. Postepy higieny i medycyny doswiadczalnej (Online). vol 66. 2013-05-02. PMID:22706112. |
moreover, leptin directly induced hypertrophy and hyperplasia in human and rodent cardiomyocytes, accompanied by cardiac extracellular matrix remodelling. |
2013-05-02 |
2023-08-12 |
human |
| Kavithalakshmi Sataranatarajan, Denis Feliers, Meenalakshmi M Mariappan, Hak Joo Lee, Myung Ja Lee, Robert T Day, Hima Bindu Yalamanchili, Goutam G Choudhury, Jeffrey L Barnes, Holly Van Remmen, Arlan Richardson, Balakuntalam S Kasinat. Molecular events in matrix protein metabolism in the aging kidney. Aging cell. vol 11. issue 6. 2013-04-18. PMID:23020145. |
renal hypertrophy was evident in middle-aged and old mice and was associated with glomerulomegaly and increase in mesangial fraction occupied by extracellular matrix. |
2013-04-18 |
2023-08-12 |
mouse |
| Liming Bian, Chieh Hou, Elena Tous, Reena Rai, Robert L Mauck, Jason A Burdic. The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy. Biomaterials. vol 34. issue 2. 2013-04-15. PMID:23084553. |
increased crosslinking also promoted hypertrophic differentiation of the chondrogenically induced mscs, resulting in more matrix calcification in vitro. |
2013-04-15 |
2023-08-12 |
mouse |
| Liming Bian, Chieh Hou, Elena Tous, Reena Rai, Robert L Mauck, Jason A Burdic. The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy. Biomaterials. vol 34. issue 2. 2013-04-15. PMID:23084553. |
supplementation with inhibitors of the small gtpase pathway involved in cytoskeletal tension or myosin ii had no effect on hypertrophic differentiation and matrix calcification, indicating that the differential response is unlikely to be related to force-sensing mechanotransduction mechanisms. |
2013-04-15 |
2023-08-12 |
mouse |
| Dao-quan Tang, Ya-qin Wei, Xiao-xing Yin, Qian Lu, Hui-hui Hao, Yun-peng Zhai, Jian-yun Wang, Jin Re. In vitro suppression of quercetin on hypertrophy and extracellular matrix accumulation in rat glomerular mesangial cells cultured by high glucose. Fitoterapia. vol 82. issue 6. 2013-04-08. PMID:21605637. |
in vitro suppression of quercetin on hypertrophy and extracellular matrix accumulation in rat glomerular mesangial cells cultured by high glucose. |
2013-04-08 |
2023-08-12 |
rat |
| Inês Falcão-Pires, Adelino F Leite-Moreir. Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment. Heart failure reviews. vol 17. issue 3. 2013-04-05. PMID:21626163. |
left ventricular hypertrophy, metabolic abnormalities, extracellular matrix changes, small vessel disease, cardiac autonomic neuropathy, insulin resistance, oxidative stress, and apoptosis are the most important contributors to diabetic cardiomyopathy onset and progression. |
2013-04-05 |
2023-08-12 |
human |