| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arthur S C França, Larissa Muratori, George Carlos Nascimento, Catia Mendes Pereira, Sidarta Ribeiro, Bruno Lobão-Soare. Object recognition impairment and rescue by a dopamine D2 antagonist in hyperdopaminergic mice. Behavioural brain research. vol 308. 2017-11-21. PMID:27059337. |
we used a classical dopamine d2 antagonist, haloperidol, to modulate the levels of dopaminergic transmission in a dose-dependent manner, before or after exploring novel objects. |
2017-11-21 |
2023-08-13 |
mouse |
| Oscar A Carballo-Molina, Andrea Sánchez-Navarro, Adolfo López-Ornelas, Rolando Lara-Rodarte, Patricia Salazar, Aurelio Campos-Romo, Verónica Ramos-Mejía, Iván Velasc. Semaphorin 3C Released from a Biocompatible Hydrogel Guides and Promotes Axonal Growth of Rodent and Human Dopaminergic Neurons. Tissue engineering. Part A. vol 22. issue 11-12. 2017-11-20. PMID:27174503. |
cell therapy in experimental models of parkinson's disease replaces the lost dopamine neurons (dan), but we still need improved methods to guide dopaminergic axons (dax) of grafted neurons to make proper connections. |
2017-11-20 |
2023-08-13 |
human |
| Lei Xing, Christopher J Martyniuk, Crystal Esau, Dillon F Da Fonte, Vance L Trudea. Proteomic profiling reveals dopaminergic regulation of progenitor cell functions of goldfish radial glial cells in vitro. Journal of proteomics. vol 144. 2017-11-20. PMID:27185549. |
in this study, label-free proteomics was used to identify the proteins in a primary rgc culture and to determine the proteome response to the selective dopamine d1 receptor agonist skf 38393 (10μm), in order to better understand dopaminergic regulation of rgcs. |
2017-11-20 |
2023-08-13 |
Not clear |
| Arunangshu Das, Anita Verma, Krishna J Mukherje. Synthesis of dopamine in E. coli using plasmid-based expression system and its marked effect on host growth profiles. Preparative biochemistry & biotechnology. vol 47. issue 8. 2017-11-20. PMID:28430025. |
dopamine, secreted from dopaminergic nerve cells, serves as an important neurotransmitter. |
2017-11-20 |
2023-08-13 |
Not clear |
| Marina Candido Primi, Vinícius Gonçalves Maltarollo, Juliana Gallottini Magalhães, Matheus Malta de Sá, Carlota Oliveira Rangel-Yagui, Gustavo Henrique Goulart Trossin. Convergent QSAR studies on a series of NK₃ receptor antagonists for schizophrenia treatment. Journal of enzyme inhibition and medicinal chemistry. vol 31. issue 2. 2017-11-17. PMID:25856571. |
the dopamine hypothesis states that decreased dopaminergic neurotransmission reduces schizophrenia symptoms. |
2017-11-17 |
2023-08-13 |
Not clear |
| Tomohisa Mori, Yoshiyuki Iwase, Asami Murata, Noriyuki Iwata, Tsutomu Suzuk. Brain site- and transmitter-dependent actions of methamphetamine, morphine and antipsychotics. Behavioural brain research. vol 306. 2017-11-17. PMID:26992824. |
our findings suggest that methamphetamine differentially regulate monoaminergic systems (e.g., dopaminergic vs. 5-htnergic), and accumbal dopamine receptors are not involved in methamphetamine-induced hyperlocomotion in mice. |
2017-11-17 |
2023-08-13 |
mouse |
| Sandro Huenchuguala, Patricia Muñoz, Rebecca Graumann, Irmgard Paris, Juan Segura-Aguila. DT-diaphorase protects astrocytes from aminochrome-induced toxicity. Neurotoxicology. vol 55. 2017-11-17. PMID:27168424. |
astrocytes are exposed to aminochrome via the oxidation of dopamine that is taken up from the synaptic cleft after its release from dopaminergic neurons. |
2017-11-17 |
2023-08-13 |
Not clear |
| L M S Cordeiro, P C R Rabelo, M M Moraes, F Teixeira-Coelho, C C Coimbra, S P Wanner, D D Soare. Physical exercise-induced fatigue: the role of serotonergic and dopaminergic systems. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 50. issue 12. 2017-11-17. PMID:29069229. |
experiments with rodents, which allow direct manipulation of brain serotonin and dopamine during exercise, clearly indicate that increased serotoninergic activity reduces performance, while increased dopaminergic activity is associated with increased performance. |
2017-11-17 |
2023-08-13 |
Not clear |
| Gagan Fervaha, Fernando Caravaggio, David C Mamo, Benoit H Mulsant, Bruce G Pollock, Shinichiro Nakajima, Philip Gerretsen, Tarek K Rajji, Wanna Mar, Yusuke Iwata, Eric Plitman, Jun Ku Chung, Gary Remington, Ariel Graff-Guerrer. Lack of association between dopaminergic antagonism and negative symptoms in schizophrenia: a positron emission tomography dopamine D2/3 receptor occupancy study. Psychopharmacology. vol 233. issue 21-22. 2017-11-16. PMID:27557949. |
lack of association between dopaminergic antagonism and negative symptoms in schizophrenia: a positron emission tomography dopamine d2/3 receptor occupancy study. |
2017-11-16 |
2023-08-13 |
Not clear |
| T Dahoun, S V Trossbach, N J Brandon, C Korth, O D Howe. The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28140405. |
here we summarise the impact of disc1 disruption on the dopamine system in animal models, considering its effects on presynaptic dopaminergic function (tyrosine hydroxylase levels, dopamine transporter levels, dopamine levels at baseline and after amphetamine administration) and postsynaptic dopaminergic function (dopamine d1 and d2 receptor levels, dopamine receptor-binding potential and locomotor activity after amphetamine administration). |
2017-11-16 |
2023-08-13 |
Not clear |
| M Toritsuka, S Kimoto, K Muraki, M Kitagawa, T Kishimoto, A Sawa, K Tanigak. Regulation of striatal dopamine responsiveness by Notch/RBP-J signaling. Translational psychiatry. vol 7. issue 3. 2017-11-16. PMID:28267151. |
rbp-j deficiency drastically reduced dopamine release in the striatum and caused a subtle decrease in the number of dopaminergic neurons. |
2017-11-16 |
2023-08-13 |
Not clear |
| Éva M Szegő, Ellen Gerhardt, Tiago F Outeir. Sirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway. Neurobiology of aging. vol 56. 2017-11-16. PMID:28478325. |
proper and efficient differentiation of dopaminergic (da) neurons is essential for the cell-based dopamine replacement strategies that have become an attractive therapeutical option in parkinson's disease, a disorder typically known for the degeneration of the nigral da neurons. |
2017-11-16 |
2023-08-13 |
mouse |
| Maria Xilouri, Oeystein Roed Brekk, Alexia Polissidis, Margarita Chrysanthou-Piterou, Ismini Kloukina, Leonidas Stefani. Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats. Autophagy. vol 12. issue 11. 2017-11-13. PMID:27541985. |
strikingly, lamp2a downregulation resulted in progressive loss of nigral dopaminergic neurons, severe reduction in striatal dopamine levels/terminals, increased astro- and microgliosis and relevant motor deficits. |
2017-11-13 |
2023-08-13 |
rat |
| Nicolas Carriere, Jean-Louis Bourriez, Arnaud Delval, Philippe Derambure, Luc Defebvre, Kathy Dujardi. Impulse Control Disorders in Parkinson's Disease are Associated with Alterations in Reward-Related Cortical Oscillations. Journal of Parkinson's disease. vol 6. issue 3. 2017-11-09. PMID:27372215. |
impulse control disorders (icds) in parkinson's disease (pd) are related to treatment with dopamine agonists, which is thought to deregulate the dopaminergic mesolimbic pathway and impair reward evaluation. |
2017-11-09 |
2023-08-13 |
Not clear |
| Yoon-Sang Oh, Ji Ho Choi, Do-Young Kwo. Classification of Scans Without Evidence of Dopamine Deficit (SWEDD) According to the Olfactory Function. Journal of Parkinson's disease. vol 6. issue 4. 2017-11-09. PMID:27567887. |
scans without evidence of dopaminergic deficit (swedd), a heterogeneous disorder, refers to patients with normal dopamine transporter scan presumed to have parkinson's disease (pd). |
2017-11-09 |
2023-08-13 |
Not clear |
| E A Evers, P Stiers, J G Ramaeker. High reward expectancy during methylphenidate depresses the dopaminergic response to gain and loss. Social cognitive and affective neuroscience. vol 12. issue 2. 2017-11-09. PMID:27677943. |
these findings suggest that striatal tonic dopamine levels constitute an average reward expectation signal that modulates the phasic dopaminergic response to reward. |
2017-11-09 |
2023-08-13 |
human |
| Nadja P Maric, Milica J Jovicic, Marina Mihaljevic, Cedo Miljevi. Improving Current Treatments for Schizophrenia. Drug development research. vol 77. issue 7. 2017-11-08. PMID:27633376. |
all currently approved antipsychotic drugs block dopamine receptors, indicating that manipulation of dopaminergic function is fundamental to a therapeutic response in psychosis. |
2017-11-08 |
2023-08-13 |
Not clear |
| Nico Bunzeck, Christiane Thie. Neurochemical modulation of repetition suppression and novelty signals in the human brain. Cortex; a journal devoted to the study of the nervous system and behavior. vol 80. 2017-11-07. PMID:26625882. |
finally, we review studies on neural novelty signals in the dopaminergic mesolimbic system, and conclude that dopamine (da) regulates the temporal aspects of novelty processing and closely relates to long-term memory encoding rather than behavioral priming. |
2017-11-07 |
2023-08-13 |
human |
| Kaylena A Ehgoetz Martens, Shannon C Lefaivre, Eric N Beck, Rebecca Chow, Frederico Pieruccini-Faria, Colin G Ellard, Quincy J Almeid. Anxiety provokes balance deficits that are selectively dopa-responsive in Parkinson's disease. Neuroscience. vol 340. 2017-11-07. PMID:27856344. |
dopamine appears to modulate anxiety, but further research is needed to evaluate whether dopaminergic treatment is optimal for anxiety induced balance deficits. |
2017-11-07 |
2023-08-13 |
human |
| Melike Sever, Mesut Turkyilmaz, Cansu Sevinc, Aysen Cakir, Busra Ocalan, Mehmet Cansev, Mustafa O Guler, Ayse B Tekina. Regenerative effects of peptide nanofibers in an experimental model of Parkinson's disease. Acta biomaterialia. vol 46. 2017-11-06. PMID:27619838. |
parkinson's disease (pd) is characterized by progressive degeneration of dopaminergic nigrostriatal neurons and reduction in striatal dopamine levels. |
2017-11-06 |
2023-08-13 |
rat |