| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander A Nevue, Richard A Felix, Christine V Portfor. Dopaminergic projections of the subparafascicular thalamic nucleus to the auditory brainstem. Hearing research. vol 341. 2018-02-13. PMID:27620513. |
the superior olivary complex (soc) is also a likely target of dopaminergic projections from the spf because it receives projections from the spf and contains fibers and terminals immunoreactive for tyrosine hydroxylase, the rate limiting enzyme in dopamine synthesis. |
2018-02-13 |
2023-08-13 |
Not clear |
| Maria Lindahl, Mart Saarma, Päivi Lindhol. Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential. Neurobiology of disease. vol 97. issue Pt B. 2018-02-12. PMID:27425895. |
cerebral dopamine neurotrophic factor (cdnf) and mesencephalic astrocyte-derived neurotrophic factor (manf) promote the survival of midbrain dopaminergic neurons which degenerate in parkinson's disease (pd). |
2018-02-12 |
2023-08-13 |
mouse |
| Audrey Chabrat, Guillaume Brisson, Hélène Doucet-Beaupré, Charleen Salesse, Marcos Schaan Profes, Axelle Dovonou, Cléophace Akitegetse, Julien Charest, Suzanne Lemstra, Daniel Côté, R Jeroen Pasterkamp, Monica I Abrudan, Emmanouil Metzakopian, Siew-Lan Ang, Martin Lévesqu. Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation. Nature communications. vol 8. issue 1. 2018-02-08. PMID:29038581. |
these findings identify lmx1a/b, otx2, and plxnc1 as determinants of dopaminergic circuit formation and should assist in engineering mesodiencephalic dopamine neurons capable of regenerating appropriate connections for cell therapy.midbrain dopaminergic neurons (mdas) in the vta and snpc project to different regions and form distinct circuits. |
2018-02-08 |
2023-08-13 |
Not clear |
| Annika H Runegaard, Kathrine L Jensen, Ciarán M Fitzpatrick, Ditte Dencker, Pia Weikop, Ulrik Gether, Mattias Rickha. Preserved dopaminergic homeostasis and dopamine-related behaviour in hemizygous TH-Cre mice. The European journal of neuroscience. vol 45. issue 1. 2018-02-01. PMID:27453291. |
our data show that th-cre mice display preserved dopaminergic homeostasis with unaltered levels of th and dopamine as well as unaffected dopamine turnover in striatum. |
2018-02-01 |
2023-08-13 |
mouse |
| Annika H Runegaard, Kathrine L Jensen, Ciarán M Fitzpatrick, Ditte Dencker, Pia Weikop, Ulrik Gether, Mattias Rickha. Preserved dopaminergic homeostasis and dopamine-related behaviour in hemizygous TH-Cre mice. The European journal of neuroscience. vol 45. issue 1. 2018-02-01. PMID:27453291. |
th-cre mice also show preserved dopamine transporter expression and function supporting sustained dopaminergic transmission. |
2018-02-01 |
2023-08-13 |
mouse |
| Philippe Jawinski, Sophie Tegelkamp, Christian Sander, Madlen Häntzsch, Jue Huang, Nicole Mauche, Markus Scholz, Janek Spada, Christine Ulke, Ralph Burkhardt, Andreas Reif, Ulrich Hegerl, Tilman Hensc. Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep. Chronobiology international. vol 33. issue 7. 2018-01-31. PMID:27148829. |
however, there is no consensus on the impact of two established dopaminergic gene variants: the catechol-o-methyltransferase val158met (comt val158met; rs4680) and the dopamine d4 receptor exon iii variable-number-of-tandem-repeat polymorphism (drd4 vntr). |
2018-01-31 |
2023-08-13 |
human |
| Hongliang Yi, Xiaohang Bao, Xiaotong Tang, Xiaotang Fan, Haiwei X. Estrogen modulation of calretinin and BDNF expression in midbrain dopaminergic neurons of ovariectomised mice. Journal of chemical neuroanatomy. vol 77. 2018-01-31. PMID:27211874. |
estrogen attenuates the loss of dopamine neurons from the substantia nigra in animal models of parkinson's disease (pd) and excitatory amino-acid induced neurotoxicity by interactions with brain-derived neurotrophic factor (bdnf), and calretinin (cr) containing dopaminergic (da) neurons. |
2018-01-31 |
2023-08-13 |
mouse |
| Erika Nallely Orendain-Jaime, Jorge Manuel Ortega-Ibarra, Silvia Josefina López-Pére. Evidence of sexual dimorphism in D1 and D2 dopaminergic receptors expression in frontal cortex and striatum of young rats. Neurochemistry international. vol 100. 2018-01-31. PMID:27600160. |
d1 and d2 receptors are key mediators of dopaminergic signaling in the brain, and since the manifestations of pathologies related to dopamine are different in female and male patients, it is important to analyze if there are sex-related differences in dopaminergic markers. |
2018-01-31 |
2023-08-13 |
rat |
| Pablo Garrido-Gil, Ana I Rodriguez-Perez, Patricia Fernandez-Rodriguez, Jose L Lanciego, Jose L Labandeira-Garci. Expression of angiotensinogen and receptors for angiotensin and prorenin in the rat and monkey striatal neurons and glial cells. Brain structure & function. vol 222. issue 6. 2018-01-30. PMID:28161727. |
in addition to the interaction between angiotensin and dopamine receptors in dopaminergic neurons to regulate dopamine release, interaction between angiotensin and dopamine receptors in projection striatal neurons may further modulate the effects of dopamine on the direct and indirect pathways by fine-tuning striatal dopaminergic neurotransmission. |
2018-01-30 |
2023-08-13 |
rat |
| Chandrashekhar D Borkar, Manoj A Upadhya, Gajanan P Shelkar, Nishikant K Subhedar, Dadasaheb M Kokar. Neuropeptide Y system in accumbens shell mediates ethanol self-administration in posterior ventral tegmental area. Addiction biology. vol 21. issue 4. 2018-01-29. PMID:25929272. |
as npy and dopamine systems in reward areas are known to interact, we suggest that npy inputs from arc and cea may play an important role in modulation of the dopaminergic system in the acbsh and consequently influence the ethanol induced reward and addiction. |
2018-01-29 |
2023-08-13 |
rat |
| Maowen Ba, Min Kong, Lina Guan, Maoli Yi, Hongli Zhan. Repetitive transcranial magnetic stimulation (rTMS) improves behavioral and biochemical deficits in levodopa-induced dyskinetic rats model. Oncotarget. vol 7. issue 37. 2018-01-29. PMID:27613848. |
after ending the experiments, we further determined tyrosine hydroxylase (th)-positive dopaminergic neurons number by immunohistochemistry, dopamine levels by hplc, glial cell line-derived neurotrophic factor (gdnf) levels by elisa, nr2b tyrosine phosphorylation and interactions of nr2b with fyn by immunoblotting and immunoprecipitation. |
2018-01-29 |
2023-08-13 |
rat |
| Maowen Ba, Min Kong, Lina Guan, Maoli Yi, Hongli Zhan. Repetitive transcranial magnetic stimulation (rTMS) improves behavioral and biochemical deficits in levodopa-induced dyskinetic rats model. Oncotarget. vol 7. issue 37. 2018-01-29. PMID:27613848. |
the results demonstrated that rtms obviously attenuated aims scores, reduced the loss of nigral dopaminergic neurons and the fluctuations of striatal dopamine levels. |
2018-01-29 |
2023-08-13 |
rat |
| Yi-Ming Shao, Xiaohua Ma, Priyankar Paira, Aaron Tan, Deron Raymond Herr, Kah Leong Lim, Chee Hoe Ng, Gopalakrishnan Venkatesan, Karl-Norbert Klotz, Stephanie Federico, Giampiero Spalluto, Siew Lee Cheong, Yu Zong Chen, Giorgia Pastori. Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A2A and dopamine D2 receptors for Parkinson's disease treatment. PloS one. vol 13. issue 1. 2018-01-29. PMID:29304113. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by progressive loss of dopaminergic neurons in the substantia nigra of the human brain, leading to depletion of dopamine production. |
2018-01-29 |
2023-08-13 |
human |
| M Morales, D H Roo. Glutamate neurons within the midbrain dopamine regions. Neuroscience. vol 282. 2018-01-26. PMID:24875175. |
midbrain dopamine regions contain at least three neuronal phenotypes: dopaminergic, gabaergic, and glutamatergic. |
2018-01-26 |
2023-08-13 |
mouse |
| M Barro. The ventral tegmentum and dopamine: A new wave of diversity. Neuroscience. vol 282. 2018-01-26. PMID:25453764. |
this special issue of neuroscience gathered some experts in the field to review the connectivity of the ventral mesencephalic dopaminergic complex, its cellular heterogeneity with attention given to glutamate neurons, the d2 autoreceptor and the cholinergic controls of dopamine activity, the influence of neurotrophins, the controls of bursting activity and the heterogeneity of neuronal activity across traits and states, the pedunculopontine tegmental and the sensory controls of dopamine activity, the sex-dependent diversity, the links between circadian and dopamine systems, the functional antero-posterior heterogeneity of the vta and the role of its gaba tail (tvta/rostromedial tegmental nucleus (rmtg)), the functional heterogeneity of the vta outputs, the place of dopamine in cortico-basal ganglia circuitry, the different roles of the d1 and d2 striatal pathways and the role of dopamine in associative learning and memory. |
2018-01-26 |
2023-08-13 |
human |
| Devon N Gangi, Daniel S Messinger, Eden R Martin, Michael L Cuccar. Dopaminergic variants in siblings at high risk for autism: Associations with initiating joint attention. Autism research : official journal of the International Society for Autism Research. vol 9. issue 11. 2018-01-26. PMID:26990357. |
the neurotransmitter dopamine is linked to brain areas associated with reward, motivation, and attention, and common dopaminergic variants have been associated with attention difficulties. |
2018-01-26 |
2023-08-13 |
Not clear |
| Devon N Gangi, Daniel S Messinger, Eden R Martin, Michael L Cuccar. Dopaminergic variants in siblings at high risk for autism: Associations with initiating joint attention. Autism research : official journal of the International Society for Autism Research. vol 9. issue 11. 2018-01-26. PMID:26990357. |
higher dopamine gene scores (indicative of less efficient dopaminergic functioning) were associated with lower levels of ija in the first year for high-risk siblings, while the opposite pattern emerged in low-risk siblings. |
2018-01-26 |
2023-08-13 |
Not clear |
| Marta Vicente-Rodríguez, Loreto Rojo Gonzalez, Esther Gramage, Rosalía Fernández-Calle, Ying Chen, Carmen Pérez-García, Marcel Ferrer-Alcón, María Uribarri, Alexis Bailey, Gonzalo Herradó. Pleiotrophin overexpression regulates amphetamine-induced reward and striatal dopaminergic denervation without changing the expression of dopamine D1 and D2 receptors: Implications for neuroinflammation. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 11. 2018-01-26. PMID:27642078. |
pleiotrophin overexpression regulates amphetamine-induced reward and striatal dopaminergic denervation without changing the expression of dopamine d1 and d2 receptors: implications for neuroinflammation. |
2018-01-26 |
2023-08-13 |
mouse |
| Linde Boekhoudt, Azar Omrani, Mieneke C M Luijendijk, Inge G Wolterink-Donselaar, Ellen C Wijbrans, Geoffrey van der Plasse, Roger A H Ada. Chemogenetic activation of dopamine neurons in the ventral tegmental area, but not substantia nigra, induces hyperactivity in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 11. 2018-01-26. PMID:27712862. |
although hyperactivity has been linked to dopaminergic signalling, the causal relationship between midbrain dopamine neuronal activity and locomotor hyperactivity remains unknown. |
2018-01-26 |
2023-08-13 |
rat |
| Troels Rahbek-Clemmensen, Matthew D Lycas, Simon Erlendsson, Jacob Eriksen, Mia Apuschkin, Frederik Vilhardt, Trine N Jørgensen, Freja H Hansen, Ulrik Gethe. Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains. Nature communications. vol 8. issue 1. 2018-01-26. PMID:28963530. |
by mediating rapid reuptake of extracellular dopamine, the dopamine transporter is critical for spatiotemporal control of dopaminergic neurotransmission. |
2018-01-26 |
2023-08-13 |
Not clear |