| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Angelina Rakovska, Maria Baranyi, Katalin Windisch, Polina Petkova-Kirova, Hristo Gagov, Reni Kalfi. Neurochemical evidence that cocaine- and amphetamine-regulated transcript (CART) 55-102 peptide modulates the dopaminergic reward system by decreasing the dopamine release in the mouse nucleus accumbens. Brain research bulletin. vol 134. 2018-05-07. PMID:28802898. |
neurochemical evidence that cocaine- and amphetamine-regulated transcript (cart) 55-102 peptide modulates the dopaminergic reward system by decreasing the dopamine release in the mouse nucleus accumbens. |
2018-05-07 |
2023-08-13 |
mouse |
| Jaung-Geng Lin, Chao-Jung Chen, Han-Bin Yang, Yi-Hung Chen, Shih-Ya Hun. Electroacupuncture Promotes Recovery of Motor Function and Reduces Dopaminergic Neuron Degeneration in Rodent Models of Parkinson's Disease. International journal of molecular sciences. vol 18. issue 9. 2018-05-03. PMID:28837077. |
the pathological hallmark of pd is a progressive loss of dopaminergic neurons in the substantia nigra (sn) pars compacta in the brain, ultimately resulting in severe striatal dopamine deficiency and the development of primary motor symptoms (e.g., resting tremor, bradykinesia) in pd. |
2018-05-03 |
2023-08-13 |
mouse |
| Dongxu Gao, Chonggang Wang, Zhihui Xi, Yixi Zhou, Yuanchuan Wang, Zhenghong Zu. Early-Life Benzo[a]Pyrene Exposure Causes Neurodegenerative Syndromes in Adult Zebrafish (Danio rerio) and the Mechanism Involved. Toxicological sciences : an official journal of the Society of Toxicology. vol 157. issue 1. 2018-05-02. PMID:28329817. |
we found that bap decreased locomotor and cognitive ability, neurotransmitter levels of dopamine, 3,4-dihydroxyphenylacetic acid and norepinephrine; and induced loss of dopaminergic neurons and resulted in neurodegeneration. |
2018-05-02 |
2023-08-13 |
zebrafish |
| Agnete Kirkeby, Malin Parmar, Roger A Barke. Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD). Progress in brain research. vol 230. 2018-05-01. PMID:28552228. |
the treatment of parkinson's disease (pd) has for over 50 years relied on dopaminergic therapies that are highly effective especially in the early years of the condition, but ultimately are limited by the development of side effects that relate to the nonphysiological stimulation of dopamine receptors including in nonstriatal areas. |
2018-05-01 |
2023-08-13 |
human |
| María Isabel Miranda, José Alejandro Rangel-Hernández, Gabriela Vera-Rivera, Nadia Edith García-Medina, Gerardo Soto-Alonso, Gabriela Rodríguez-García, Luis Núñez-Jaramill. The role of dopamine D2 receptors in the nucleus accumbens during taste-aversive learning and memory extinction after long-term sugar consumption. Neuroscience. vol 359. 2018-04-30. PMID:28716589. |
changes in dopamine release in the nacc have been observed during consumption of a sweet taste and during compulsive consumption of dietary sugars, suggesting that nacc dopaminergic transmission is strongly correlated with taste familiarity and the hedonic value content. |
2018-04-30 |
2023-08-13 |
rat |
| Nataliya Titova, K Ray Chaudhur. Personalized Medicine and Nonmotor Symptoms in Parkinson's Disease. International review of neurobiology. vol 134. 2018-04-27. PMID:28805572. |
these endophenotypes may be underpinned by considerable nondopaminergic dysfunction; however, conventional treatment of pd continues to be mostly reliant on dopamine replacement strategy or manipulation of brain dopaminergic pathways. |
2018-04-27 |
2023-08-13 |
Not clear |
| Ryul Kim, Beomseok Jeo. Nonmotor Effects of Conventional and Transdermal Dopaminergic Therapies in Parkinson's Disease. International review of neurobiology. vol 134. 2018-04-27. PMID:28805592. |
although a range of nms have a dopaminergic pathophysiological basis, this fact is underrecognized, and thus, they are often regarded as dopamine unresponsive symptoms. |
2018-04-27 |
2023-08-13 |
Not clear |
| Roberta Biundo, Eleonora Fiorenzato, Angelo Antonin. Nonmotor Symptoms and Natural History of Parkinson's Disease: Evidence From Cognitive Dysfunction and Role of Noninvasive Interventions. International review of neurobiology. vol 133. 2018-04-26. PMID:28802926. |
some nms fluctuate in response to dopaminergic treatment and are relieved by dopamine replacement therapy, other are insensitive to current therapeutic strategies. |
2018-04-26 |
2023-08-13 |
Not clear |
| Hemalatha Sasidharakurup, Nidheesh Melethadathil, Bipin Nair, Shyam Diwaka. A Systems Model of Parkinson's Disease Using Biochemical Systems Theory. Omics : a journal of integrative biology. vol 21. issue 8. 2018-04-26. PMID:28816645. |
simulations suggest that dopamine levels were reduced significantly due to an increase in dopaminergic quinones and 3,4-dihydroxyphenylacetaldehyde (dopal) relating to imbalances compared to control during pd progression. |
2018-04-26 |
2023-08-13 |
Not clear |
| Amy R Dunn, Kristen A Stout, Minagi Ozawa, Kelly M Lohr, Carlie A Hoffman, Alison I Bernstein, Yingjie Li, Minzheng Wang, Carmelo Sgobio, Namratha Sastry, Huaibin Cai, W Michael Caudle, Gary W Mille. Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 11. 2018-04-23. PMID:28246328. |
these data establish sv2c as a mediator of dopamine neuron function and suggest that sv2c disruption is a unique feature of pd that likely contributes to dopaminergic dysfunction. |
2018-04-23 |
2023-08-13 |
mouse |
| Flavia Maria Sutera, Libero Italo Giannola, Denise Murgia, Viviana De Car. Assessment of in vivo organ-uptake and in silico prediction of CYP mediated metabolism of DA-Phen, a new dopaminergic agent. Computational biology and chemistry. vol 71. 2018-04-23. PMID:28985485. |
as a consequence, it is possible to assume that da-phen acts as dopaminergic modulator per se and not as a dopamine prodrug, thus avoiding peripheral release and toxic side effects due to the endogenous neurotransmitter. |
2018-04-23 |
2023-08-13 |
human |
| Sebastian Markett, Marcel A de Reus, Martin Reuter, Christian Montag, Bernd Weber, Jan-Christoph Schoene-Bake, Martijn P van den Heuve. Variation on the dopamine D2 receptor gene (DRD2) is associated with basal ganglia-to-frontal structural connectivity. NeuroImage. vol 155. 2018-04-20. PMID:28392487. |
common variation on the dopamine d2 receptor (drd2) gene has been linked to individual differences in dopaminergic signaling and was also repeatedly associated to cognitive markers. |
2018-04-20 |
2023-08-13 |
human |
| Sebastian Markett, Marcel A de Reus, Martin Reuter, Christian Montag, Bernd Weber, Jan-Christoph Schoene-Bake, Martijn P van den Heuve. Variation on the dopamine D2 receptor gene (DRD2) is associated with basal ganglia-to-frontal structural connectivity. NeuroImage. vol 155. 2018-04-20. PMID:28392487. |
our results indicate that structural connectivity could serve as a conceptual link between genetically determined individual differences in dopaminergic activity and effects of dopamine challenges on executive functioning. |
2018-04-20 |
2023-08-13 |
human |
| Jesús M López, Agustín Gonzále. Organization of the catecholaminergic systems in the brain of lungfishes, the closest living relatives of terrestrial vertebrates. The Journal of comparative neurology. vol 525. issue 14. 2018-04-19. PMID:28649777. |
hypothalamic and diencephalic groups were detected and, in particular, the dopaminergic nucleus of the periventricular organ was evidenced with dopamine antibodies but not with anti-tyrosine hydroxylase. |
2018-04-19 |
2023-08-13 |
Not clear |
| Peter J Gaskill, Douglas R Miller, Joyonna Gamble-George, Hideaki Yano, Habibeh Khoshboue. HIV, Tat and dopamine transmission. Neurobiology of disease. vol 105. 2018-04-18. PMID:28457951. |
specifically, data indicate that tat may directly impact dopaminergic neurotransmission, by modulating the function of the dopamine transporter and specifically damaging dopamine-rich regions of the cns. |
2018-04-18 |
2023-08-13 |
human |
| Andrea Herrera-Solis, Wendy Herrera-Morales, Luis Nunez-Jaramillo, Oscar Arias-Carrio. Dopaminergic Modulation of Sleep-Wake States. CNS & neurological disorders drug targets. vol 16. issue 4. 2018-04-16. PMID:28322171. |
the effects of dopaminergic agents, nevertheless, are mediated by two families of dopamine receptors, d1 and d2-like receptors; the first family increases adenylyl cyclase activity and the second inhibits adenylyl cyclase. |
2018-04-16 |
2023-08-13 |
Not clear |
| Kimberly A Kempadoo, Eugene V Mosharov, Se Joon Choi, David Sulzer, Eric R Kande. Dopamine release from the locus coeruleus to the dorsal hippocampus promotes spatial learning and memory. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 51. 2018-04-13. PMID:27930324. |
we have explored this apparent paradox using optogenetic, biochemical, and behavioral approaches and found that dopaminergic axons and subsequent dopamine release in the dorsal hippocampus originate from neurons of the locus coeruleus (lc). |
2018-04-13 |
2023-08-13 |
Not clear |
| Guillermo Gervasini, Luz M González, Carmen Gamero-Villarroel, Sonia Mota-Zamorano, Juan Antonio Carrillo, Isalud Flores, Angustias García-Herrái. Effect of dopamine receptor D4 (DRD4) haplotypes on general psychopathology in patients with eating disorders. Gene. vol 654. 2018-04-13. PMID:29455021. |
among the many candidate genes analyzed in eating disorder (ed) patients, those involved in dopaminergic functions may be of special relevance, as dopamine is known to play a significant role in feeding behavior, the distortion of body image, hyperactivity and reward and reinforcement processes. |
2018-04-13 |
2023-08-13 |
Not clear |
| Jung-Hoon Koo, Yong-Chul Jang, Dong-Ju Hwang, Hyun-Seob Um, Nam-Hee Lee, Jae-Hoon Jung, Joon-Yong Ch. Treadmill exercise produces neuroprotective effects in a murine model of Parkinson's disease by regulating the TLR2/MyD88/NF-κB signaling pathway. Neuroscience. vol 356. 2018-04-12. PMID:28527958. |
parkinson's disease (pd) is characterized by progressive dopamine depletion and a loss of dopaminergic neurons in the substantia nigra pars compacta (snpc). |
2018-04-12 |
2023-08-13 |
mouse |
| Kinan Muhammed, Sanjay Manohar, Michael Ben Yehuda, Trevor T-J Chong, George Tofaris, Graham Lennox, Marko Bogdanovic, Michele Hu, Masud Husai. Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson's disease. Brain : a journal of neurology. vol 139. issue Pt 10. 2018-04-10. PMID:27452600. |
thirty patients were examined on and off their dopaminergic medication in two counterbalanced sessions, so that the effect of dopamine on reward sensitivity could be assessed. |
2018-04-10 |
2023-08-13 |
human |