| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katie E Yoest, Jacqueline A Quigley, Jill B Becke. Rapid effects of ovarian hormones in dorsal striatum and nucleus accumbens. Hormones and behavior. vol 104. 2019-05-31. PMID:29626485. |
research on how dopaminergic systems regulate behavior in both males and females is crucial for developing a full appreciation of dopamine's role in both natural and drug-induced behaviors. |
2019-05-31 |
2023-08-13 |
rat |
| Xueliang Fan, Yuping Donsante, H A Jinnah, Ellen J Hes. Dopamine Receptor Agonist Treatment of Idiopathic Dystonia: A Reappraisal in Humans and Mice. The Journal of pharmacology and experimental therapeutics. vol 365. issue 1. 2019-05-28. PMID:29348266. |
although dystonia is often associated with abnormal dopamine neurotransmission, dopaminergic drugs are not currently used to treat dystonia because there is a general view that dopaminergic drugs are ineffective. |
2019-05-28 |
2023-08-13 |
mouse |
| Tayyabah Yousaf, Gennaro Pagano, Flavia Niccolini, Marios Politi. Excessive daytime sleepiness may be associated with caudate denervation in Parkinson disease. Journal of the neurological sciences. vol 387. 2019-05-28. PMID:29571867. |
using the parkinson's progression markers initiative database, we performed a case-control study to investigate whether dopaminergic deficit is associated with the development of eds using dopaminergic specific single photon emission computed tomography (spect) molecular imaging of dopamine transporters (dat). |
2019-05-28 |
2023-08-13 |
Not clear |
| Kristina Simonyan, Hyun Cho, Azadeh Hamzehei Sichani, Estee Rubien-Thomas, Mark Hallet. The direct basal ganglia pathway is hyperfunctional in focal dystonia. Brain : a journal of neurology. vol 140. issue 12. 2019-05-23. PMID:29087445. |
our findings paralleled abnormally decreased dopaminergic function via the indirect basal ganglia pathway and decreased symptom-induced phasic striatal dopamine release in writer’s cramp and laryngeal dystonia. |
2019-05-23 |
2023-08-13 |
Not clear |
| Kristina Simonyan, Hyun Cho, Azadeh Hamzehei Sichani, Estee Rubien-Thomas, Mark Hallet. The direct basal ganglia pathway is hyperfunctional in focal dystonia. Brain : a journal of neurology. vol 140. issue 12. 2019-05-23. PMID:29087445. |
however, despite topological disorganization of dopaminergic function, alterations of dopamine d1 and d2 receptors were somatotopically localized within the striatal hand and larynx representations in writer’s cramp and laryngeal dystonia, respectively. |
2019-05-23 |
2023-08-13 |
Not clear |
| Upasana Ganguly, Anirban Ganguly, Oishimaya Sen, Gargi Ganguly, Roberto Cappai, Arghyadip Sahoo, Sasanka Chakrabart. Dopamine Cytotoxicity on SH-SY5Y Cells: Involvement of α-Synuclein and Relevance in the Neurodegeneration of Sporadic Parkinson's Disease. Neurotoxicity research. vol 35. issue 4. 2019-05-23. PMID:30806984. |
the cytotoxicity of dopamine on cultured cells of neural origin has been used as a tool to explore the mechanisms of dopaminergic neurodegeneration in parkinson's disease. |
2019-05-23 |
2023-08-13 |
Not clear |
| Lorena Oliveira de Matos, Ana Luiza de Araujo Lima Reis, Lorena Terene Lopes Guerra, Leonardo de Oliveira Guarnieri, Muiara Aparecida Moraes, Nayara Soares Sena Aquino, Raphael E Szawka, Grace Schenatto Pereira, Bruno Rezende Souz. l-Dopa treatment during perinatal development leads to different behavioral alterations in female vs. male juvenile Swiss mice. Pharmacology, biochemistry, and behavior. vol 173. 2019-05-22. PMID:30102946. |
imbalances in dopamine levels during prenatal development are associated with behavioral alterations later in life, like hyperactivity and addiction, and it is possible that dopaminergic imbalances may have diverse effects during different neurodevelopmental windows. |
2019-05-22 |
2023-08-13 |
mouse |
| Anne M Landau, Aage Ko Alstrup, Helene Audrain, Steen Jakobsen, Mette Simonsen, Arne Møller, Poul Videbech, Gregers Wegener, Albert Gjedde, Doris J Doude. Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 5. 2019-05-21. PMID:28509598. |
with positron emission tomography (pet), we determined a measure of dopaminergic neurotransmission with the dopamine d1 receptor antagonist [ |
2019-05-21 |
2023-08-13 |
Not clear |
| Yingying Sun, An Ninh Pham, T David Wait. Mechanism Underlying the Effectiveness of Deferiprone in Alleviating Parkinson's Disease Symptoms. ACS chemical neuroscience. vol 9. issue 5. 2019-05-21. PMID:29381045. |
elevation in iron content as well as severe depletion of dopamine (da) as a result of iron-induced loss of dopaminergic neurons has been recognized to accompany the progression of parkinson's disease (pd). |
2019-05-21 |
2023-08-13 |
Not clear |
| Phillip Mackie, Joe Lebowitz, Leila Saadatpour, Emily Nickoloff, Peter Gaskill, Habibeh Khoshboue. The dopamine transporter: An unrecognized nexus for dysfunctional peripheral immunity and signaling in Parkinson's Disease. Brain, behavior, and immunity. vol 70. 2019-05-21. PMID:29551693. |
the dopamine transporter (dat), the main regulator of dopaminergic tone in the cns, is known to exist in lymphocytes and monocytes/macrophages, but little is known about peripheral dat biology or how dat regulates the dopaminergic tone, much less how peripheral dat alters immune function. |
2019-05-21 |
2023-08-13 |
Not clear |
| Andrew Vo, Ken N Seergobin, Penny A MacDonal. Independent effects of age and levodopa on reversal learning in healthy volunteers. Neurobiology of aging. vol 69. 2019-05-21. PMID:29894903. |
it posits that effects of dopaminergic therapy on cognition in parkinson's disease depend on baseline dopamine levels in brain regions that support different functions. |
2019-05-21 |
2023-08-13 |
human |
| Andrew Vo, Ken N Seergobin, Penny A MacDonal. Independent effects of age and levodopa on reversal learning in healthy volunteers. Neurobiology of aging. vol 69. 2019-05-21. PMID:29894903. |
we investigated whether age-related changes in baseline dopamine levels would modulate effects of dopaminergic therapy on reward learning in healthy volunteers. |
2019-05-21 |
2023-08-13 |
human |
| Adam Włodarczyk, Joanna Szarmach, Wiesław Jerzy Cubała, Mariusz Stanisław Wiglus. Benzodiazepines in combination with antipsychotic drugs for schizophrenia: GABA-ergic targeted therapy. Psychiatria Danubina. vol 29. issue Suppl 3. 2019-05-20. PMID:28953788. |
the disruption of gaba-ergic transmission in schizophrenia may induce alternations in dopaminergic neurotransmission providing no inhibitory effect to the central glutamate activity, resulting in the rise of the dopamine levels being associated with psychosis precipitation. |
2019-05-20 |
2023-08-13 |
Not clear |
| Adam Włodarczyk, Joanna Szarmach, Wiesław Jerzy Cubała, Mariusz Stanisław Wiglus. Benzodiazepines in combination with antipsychotic drugs for schizophrenia: GABA-ergic targeted therapy. Psychiatria Danubina. vol 29. issue Suppl 3. 2019-05-20. PMID:28953788. |
benzodiazepines are believed to reduce presynaptic dopamine release at the mesolimbic level and delay postsynaptic adaptation of dopaminergic neurons to antipsychotics potentiating the action of antipsychotics in resistant schizophrenia. |
2019-05-20 |
2023-08-13 |
Not clear |
| G Fond, L Boyer, F Schürhoff, F Berna, O Godin, E Bulzacka, M Andrianarisoa, L Brunel, B Aouizerate, D Capdevielle, I Chereau, N Coulon, T D'Amato, C Dubertret, J Dubreucq, C Faget, C Lançon, S Leignier, J Mallet, D Misdrahi, C Passerieux, R Rey, A Schandrin, M Urbach, P Vidailhet, P M Llorca, M Leboye. Latent toxoplasma infection in real-world schizophrenia: Results from the national FACE-SZ cohort. Schizophrenia research. vol 201. 2019-05-20. PMID:29843964. |
latent toxoplasma infection has been associated with widespread brain immune activation, increased blood brain barrier permeability, neural disruption, increased dopamine release in dopaminergic neurons, with nmda activation and with schizophrenia (sz) onset risk. |
2019-05-20 |
2023-08-13 |
human |
| Lisa-Marie Anders, Sven P Heinrich, Wolf A Lagrèze, Lutz Joachimse. Little effect of 0.01% atropine eye drops as used in myopia prevention on the pattern electroretinogram. Documenta ophthalmologica. Advances in ophthalmology. vol 138. issue 2. 2019-05-17. PMID:30680489. |
the mechanism of action is believed to involve the dopaminergic system of the retina, triggering an increased release of dopamine. |
2019-05-17 |
2023-08-13 |
Not clear |
| Rick C Helmic. The cerebral basis of Parkinsonian tremor: A network perspective. Movement disorders : official journal of the Movement Disorder Society. vol 33. issue 2. 2019-05-16. PMID:29119634. |
in particular, the role of dopamine in tremor has been heavily debated given clinical observations that tremor has a variable response to dopaminergic medication. |
2019-05-16 |
2023-08-13 |
Not clear |
| Daniel Zaldivar, Jozien Goense, Scott C Lowe, Nikos K Logothetis, Stefano Panzer. Dopamine Is Signaled by Mid-frequency Oscillations and Boosts Output Layers Visual Information in Visual Cortex. Current biology : CB. vol 28. issue 2. 2019-05-14. PMID:29307559. |
we recorded the local field potential (lfp) at different depths of primary visual cortex (v1) in anesthetized monkeys (macaca mulatta) during spontaneous activity and during visual stimulation with hollywood movie clips while pharmacologically mimicking dopaminergic neuromodulation by systemic injection of l-dopa (a metabolic precursor of dopamine). |
2019-05-14 |
2023-08-13 |
monkey |
| Phuong-Tram Nguyen, Duy-Khanh Dang, Hai-Quyen Tran, Eun-Joo Shin, Ji Hoon Jeong, Seung-Yeol Nah, Min Chang Cho, Yong Sup Lee, Choon-Gon Jang, Hyoung-Chun Ki. Methiopropamine, a methamphetamine analogue, produces neurotoxicity via dopamine receptors. Chemico-biological interactions. vol 305. 2019-05-10. PMID:30922767. |
moreover, treatment with mpa resulted in significant impairments in dopaminergic parameters [i.e., changes in dopamine level, dopamine turnover rate, tyrosine hydroxylase (th) levels, dopamine transporter (dat) expression, and vesicular monoamine transporter-2 (vmat-2) expression], and in behavioral deficits. |
2019-05-10 |
2023-08-13 |
mouse |
| Phuong-Tram Nguyen, Duy-Khanh Dang, Hai-Quyen Tran, Eun-Joo Shin, Ji Hoon Jeong, Seung-Yeol Nah, Min Chang Cho, Yong Sup Lee, Choon-Gon Jang, Hyoung-Chun Ki. Methiopropamine, a methamphetamine analogue, produces neurotoxicity via dopamine receptors. Chemico-biological interactions. vol 305. 2019-05-10. PMID:30922767. |
therefore, our results suggest that dopamine d1 and d2 receptors simultaneously mediate mpa-induced dopaminergic neurodegeneration in mice via oxidative burdens, microgliosis, and pro-apoptosis. |
2019-05-10 |
2023-08-13 |
mouse |