| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sanders A McDougall, Matthew G Apodaca, Alena Mohd-Yusof, Adrian D Mendez, Caitlin G Katz, Angie Teran, Israel Garcia-Carachure, Anthony T Quiroz, Cynthia A Crawfor. Ontogeny of cocaine-induced behaviors and cocaine pharmacokinetics in male and female neonatal, preweanling, and adult rats. Psychopharmacology. vol 235. issue 7. 2019-03-13. PMID:29671013. |
ontogenetic differences in the behavioral responsiveness to cocaine have often been attributed to the maturation of dopaminergic elements (e.g., dopamine transporters, d2 |
2019-03-13 |
2023-08-13 |
rat |
| M A van der Kooij, F Hollis, L Lozano, I Zalachoras, S Abad, O Zanoletti, J Grosse, I Guillot de Suduiraut, C Canto, C Sand. Diazepam actions in the VTA enhance social dominance and mitochondrial function in the nucleus accumbens by activation of dopamine D1 receptors. Molecular psychiatry. vol 23. issue 3. 2019-03-12. PMID:28727688. |
our data support the view that diazepam disinhibits vta dopaminergic neurons, leading to the release of dopamine into the nac where activation of d1-signaling transiently facilitates mitochondrial function, that is, increased respiration and enhanced atp levels, which ultimately enhances social competitive behavior. |
2019-03-12 |
2023-08-13 |
rat |
| Lívia Cristina R F Lins, Marina F Souza, José Marcos M Bispo, Auderlan M Gois, Thaís Cristina S Melo, Rayr Antonio S Andrade, Lucindo J Quintans-Junior, Alessandra M Ribeiro, Regina H Silva, José R Santos, Murilo Marchior. Carvacrol prevents impairments in motor and neurochemical parameters in a model of progressive parkinsonism induced by reserpine. Brain research bulletin. vol 139. 2019-03-12. PMID:29378222. |
parkinson's disease (pd) is a neurodegenerative disease characterized by a progressive degeneration of dopaminergic neurons in the substantia nigra pars compact (snpc), with consequent depletion of dopamine in the striatum, which gives rise to the characteristic motor symptoms of pd. |
2019-03-12 |
2023-08-13 |
rat |
| Yasuhide Mitsumoto, Atsushi Mor. Acute Restraint Stress Augments 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Neurotoxicity via Increased Toxin Uptake into the Brain in C57BL/6 Mice. Neuroscience bulletin. vol 34. issue 5. 2019-03-12. PMID:29987518. |
exposure to 2 h of restraint stress immediately after injection of a low dose of mptp caused a severe loss of striatal dopaminergic terminals as indicated by decreases in the dopamine transporter protein and dopamine levels compared with mptp administration alone. |
2019-03-12 |
2023-08-13 |
mouse |
| Xiaotong Zheng, Xuechai Chen, Minjun Guo, Sakhawat Ali, Yinghui Huang, Feiyi Sun, Kefu Liu, Zixuan Chen, Yulin Deng, Rugang Zhon. Changes in salsolinol production and salsolinol synthase activity in Parkinson's disease model. Neuroscience letters. vol 673. 2019-03-11. PMID:29454627. |
salsolinol is an endogenous neurotoxin derived from dopamine, and has been proved to cause the apoptosis of the dopaminergic neurons involved in the pathogenesis of parkinson's disease (pd). |
2019-03-11 |
2023-08-13 |
rat |
| Hector Rosas-Hernandez, Srinivasulu Chigurupati, James Raymick, Bonnie Robinson, Elvis Cuevas, Joseph Hanig, Sumit Sarka. Identification of altered microRNAs in serum of a mouse model of Parkinson's disease. Neuroscience letters. vol 687. 2019-03-11. PMID:30025832. |
chronic mptp treatment induced loss of dopaminergic terminals in the snpc and caudate putamen, confirmed by a decrease in the number of tyrosine hydroxylase and dopamine transporter positive cells. |
2019-03-11 |
2023-08-13 |
mouse |
| Ina Filla, Matthew R Bailey, Elke Schipani, Vanessa Winiger, Chris Mezias, Peter D Balsam, Eleanor H Simpso. Striatal dopamine D2 receptors regulate effort but not value-based decision making and alter the dopaminergic encoding of cost. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 11. 2019-03-11. PMID:30082890. |
striatal dopamine d2 receptors regulate effort but not value-based decision making and alter the dopaminergic encoding of cost. |
2019-03-11 |
2023-08-13 |
mouse |
| Soo Bin Park, Kyum-Yil Kwon, Jeong-Yoon Lee, Kayeong Im, Jun-Sang Sunwoo, Kyung Bok Lee, Hakjae Roh, Moo-Young Ahn, Suyeon Park, Soo-Jong Kim, Jungsu S Oh, Jae Seung Ki. Lack of association between dopamine transporter loss and non-motor symptoms in patients with Parkinson's disease: a detailed PET analysis of 12 striatal subregions. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 40. issue 2. 2019-03-11. PMID:30415448. |
however, it remains unclear whether dopamine depletion is related to non-motor symptoms, and which non-motor symptoms are significantly dependent on dopaminergic deficit. |
2019-03-11 |
2023-08-13 |
Not clear |
| Fatemeh Shaerzadeh, Wolfgang J Streit, Soomaayeh Heysieattalab, Habibeh Khoshboue. Methamphetamine neurotoxicity, microglia, and neuroinflammation. Journal of neuroinflammation. vol 15. issue 1. 2019-03-11. PMID:30541633. |
while the modulatory effects of meth on dopamine neurotransmission and its neurotoxicity in the central nervous system are well studied, meth's effects on modulating microglial neuroimmune functions and on eliciting neuroinflammation to affect dopaminergic neurotoxicity has attracted considerable attention in recent years. |
2019-03-11 |
2023-08-13 |
human |
| Ke Nie, Kun Wang, Deng-Feng Huang, Yu-Bin Huang, Wu Yin, Da-Long Ren, Han Wang, Bing H. Effects of circadian clock protein Per1b on zebrafish visual functions. Chronobiology international. vol 35. issue 2. 2019-03-07. PMID:29157002. |
further, partially damaged dopaminergic interplexiform cells in wild-type larvae also led to reduced behavioral contrast sensitivity, while exogenous dopamine administration effectively restored the contrast sensitivity of per1b mutants. |
2019-03-07 |
2023-08-13 |
zebrafish |
| Mathangi Sankaran, Patrick W Keeley, Li He, P Michael Iuvone, Benjamin E Rees. Dopaminergic amacrine cell number, plexus density, and dopamine content in the mouse retina: Strain differences and effects of Bax gene disruption. Experimental eye research. vol 177. 2019-03-06. PMID:30240584. |
dopaminergic amacrine cell number, plexus density, and dopamine content in the mouse retina: strain differences and effects of bax gene disruption. |
2019-03-06 |
2023-08-13 |
mouse |
| Mathangi Sankaran, Patrick W Keeley, Li He, P Michael Iuvone, Benjamin E Rees. Dopaminergic amacrine cell number, plexus density, and dopamine content in the mouse retina: Strain differences and effects of Bax gene disruption. Experimental eye research. vol 177. 2019-03-06. PMID:30240584. |
the present study assessed the overall density of the dopaminergic plexus in the inner plexiform layer in the presence of large variation in the total number of da cells, as well as their retinal dopamine content, to determine whether either of these features is conserved. |
2019-03-06 |
2023-08-13 |
mouse |
| Ping Chen, Peng Chen, Tian Li, Qi Shen, Deng-Feng Yan, Liang Zhang, Xi Chen, Yan Li, Wei Zha. Two dopamine D2-like receptor genes from the silkworm (Bombyx mori) and their evolutionary history in metazoan. Scientific reports. vol 7. issue 1. 2019-03-04. PMID:28754962. |
dopaminergic signaling is mediated through two classes of dopamine receptors, d1-like and d2-like. |
2019-03-04 |
2023-08-13 |
Not clear |
| Anne S Berry, Vyoma D Shah, Daniella J Furman, Robert L White, Suzanne L Baker, James P O'Neil, Mustafa Janabi, Mark D'Esposito, William J Jagus. Dopamine Synthesis Capacity is Associated with D2/3 Receptor Binding but Not Dopamine Release. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 6. 2019-03-04. PMID:28816243. |
though dopaminergic dysregulation characterizes a number of neuropsychiatric disorders including schizophrenia and addiction, there has been relatively little investigation into the nature of relationships across dopamine markers within healthy individuals. |
2019-03-04 |
2023-08-13 |
Not clear |
| Ben Sagot, Li Li, Fu-Ming Zho. Hyperactive Response of Direct Pathway Striatal Projection Neurons to L-dopa and D1 Agonism in Freely Moving Parkinsonian Mice. Frontiers in neural circuits. vol 12. 2019-03-04. PMID:30104963. |
dopamine (da) profoundly stimulates motor function as demonstrated by the hypokinetic motor symptoms in parkinson's disease (pd) and by the hyperkinetic motor side effects during dopaminergic treatment of pd. |
2019-03-04 |
2023-08-13 |
mouse |
| Jubao Duan, Harald H H Göring, Alan R Sanders, Winton Moy, Jessica Freda, Eugene I Drigalenko, Mark Kos, Deli He, Pablo V Gejma. Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model. Translational psychiatry. vol 8. issue 1. 2019-03-04. PMID:30115913. |
the dopaminergic hypothesis of schizophrenia (sz) postulates that dopaminergic over activity causes psychosis, a central feature of sz, based on the observation that blocking dopamine (da) improves psychotic symptoms. |
2019-03-04 |
2023-08-13 |
Not clear |
| Xiwu Zhao, Kwoon Y Wong, Dao-Qi Zhan. Mapping physiological inputs from multiple photoreceptor systems to dopaminergic amacrine cells in the mouse retina. Scientific reports. vol 7. issue 1. 2019-03-01. PMID:28801634. |
in the vertebrate retina, dopamine is synthesized and released by a specialized type of amacrine cell, the dopaminergic amacrine cell (dac). |
2019-03-01 |
2023-08-13 |
mouse |
| Hiromasa Satoh, Hidenori Suzuki, Fumihito Saito. Downregulation of Dopamine D1-like Receptor Pathways of GABAergic Interneurons in the Anterior Cingulate Cortex of Spontaneously Hypertensive Rats. Neuroscience. vol 394. 2019-03-01. PMID:30394321. |
dopaminergic neurons are the main source of dopamine (da), a neurotransmitter that acts as a neuromodulator of cognitive function in the prefrontal cortex, including the anterior cingulate cortex (acc), which receives dopaminergic inputs from the ventral tegmental area. |
2019-03-01 |
2023-08-13 |
rat |
| Rodrigo C Meza, Luciana López-Jury, Carmen C Canavier, Pablo Henn. Role of the Axon Initial Segment in the Control of Spontaneous Frequency of Nigral Dopaminergic Neurons The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 3. 2019-02-28. PMID:29217687. |
role of the axon initial segment in the control of spontaneous frequency of nigral dopaminergic neurons the spontaneous tonic discharge activity of nigral dopamine neurons plays a fundamental role in dopaminergic signaling. |
2019-02-28 |
2023-08-13 |
mouse |
| Juho-Matti Renko, Susanne Bäck, Merja H Voutilainen, T Petteri Piepponen, Ilkka Reenilä, Mart Saarma, Raimo K Tuomine. Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29349573. |
glial cell line-derived neurotrophic factor (gdnf), cerebral dopamine neurotrophic factor (cdnf), and mesencephalic astrocyte-derived neurotrophic factor (manf) have shown neuroprotective and restorative effects on nigral dopaminergic neurons in various animal models of parkinson's disease. |
2019-02-26 |
2023-08-13 |
rat |