| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juho-Matti Renko, Susanne Bäck, Merja H Voutilainen, T Petteri Piepponen, Ilkka Reenilä, Mart Saarma, Raimo K Tuomine. Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29349573. |
the results show that gdnf, cdnf, and manf have divergent effects on dopaminergic neurotransmission, as well as on dopamine synthetizing and metabolizing enzymes. |
2019-02-26 |
2023-08-13 |
rat |
| Lucas C Armstrong, Glenn E Kirsch, Nikolai B Fedorov, Caiyun Wu, Yuri A Kuryshev, Abby L Sewell, Zhiqi Liu, Arianne L Motter, Carmine S Leggett, Michael S Or. High-Throughput Patch Clamp Screening in Human α6-Containing Nicotinic Acetylcholine Receptors. SLAS discovery : advancing life sciences R & D. vol 22. issue 6. 2019-02-21. PMID:28298165. |
the α6β2β3 nachr subtype is expressed in terminals of dopaminergic neurons that project to the nucleus accumbens and striatum and modulate dopamine release in brain regions involved in nicotine addiction. |
2019-02-21 |
2023-08-13 |
human |
| Qiu T Ruan, Neema Yazdani, Jacob A Beierle, Kathryn M Hixson, Kristen E Hokenson, Daniel J Apicco, Kimberly P Luttik, Karen Zheng, Brandon F Maziuk, Peter E A Ash, Karen K Szumlinski, Shelley J Russek, Benjamin Wolozin, Camron D Bryan. Changes in neuronal immunofluorescence in the C- versus N-terminal domains of hnRNP H following D1 dopamine receptor activation. Neuroscience letters. vol 684. 2019-02-20. PMID:30003938. |
methamphetamine initiates post-synaptic d1 dopamine receptor signaling indirectly by binding to pre-synaptic dopamine transporters and vesicular monoamine transporters of midbrain dopaminergic neurons which triggers reverse transport and accumulation of dopamine at the synapse. |
2019-02-20 |
2023-08-13 |
rat |
| Seong Su Kang, Eun Hee Ahn, Zhentao Zhang, Xia Liu, Fredric P Manfredsson, Ivette M Sandoval, Susov Dhakal, P Michael Iuvone, Xuebing Cao, Keqiang Y. α-Synuclein stimulation of monoamine oxidase-B and legumain protease mediates the pathology of Parkinson's disease. The EMBO journal. vol 37. issue 12. 2019-02-19. PMID:29769405. |
dopaminergic neurodegeneration in parkinson's disease (pd) is associated with abnormal dopamine metabolism by mao-b (monoamine oxidase-b) and intracellular α-synuclein (α-syn) aggregates, called the lewy body. |
2019-02-19 |
2023-08-13 |
mouse |
| Muhammad M Hossain, Blair Weig, Kenneth Reuhl, Marla Gearing, Long-Jun Wu, Jason R Richardso. The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Na Experimental neurology. vol 308. 2019-02-19. PMID:30017881. |
the anti-parkinsonian drug zonisamide reduces neuroinflammation: role of microglial na parkinson's disease (pd), the second most common age-related progressive neurodegenerative disorder, is characterized by dopamine depletion and the loss of dopaminergic (da) neurons with accompanying neuroinflammation. |
2019-02-19 |
2023-08-13 |
Not clear |
| Yujung Chang, Junsang Yoo, Hongwon Kim, Hi-Joon Park, Songhee Jeon, Jongpil Ki. Salusin-β mediate neuroprotective effects for Parkinson's disease. Biochemical and biophysical research communications. vol 503. issue 3. 2019-02-18. PMID:30017195. |
importantly, intranasal administration of salusin-β in a pd mouse model show the neuroprotection of dopaminergic neurons and increased the survival of midbrain dopamine neurons. |
2019-02-18 |
2023-08-13 |
mouse |
| Sakari Leino, Sini K Koski, Raisa Hänninen, Tuukka Tapanainen, Saara Rannanpää, Outi Salmine. Attenuated dopaminergic neurodegeneration and motor dysfunction in hemiparkinsonian mice lacking the α5 nicotinic acetylcholine receptor subunit. Neuropharmacology. vol 138. 2019-02-13. PMID:29940207. |
effects of α5 gene deletion on the dopaminergic system were investigated by measuring ex vivo striatal dopamine transporter function and protein expression, dopamine and metabolite tissue concentrations and dopamine receptor mrna expression. |
2019-02-13 |
2023-08-13 |
mouse |
| Carmelo Sgobio, Junbing Wu, Wang Zheng, Xi Chen, Jing Pan, Armando G Salinas, Margaret I Davis, David M Lovinger, Huaibin Ca. Aldehyde dehydrogenase 1-positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum. Scientific reports. vol 7. issue 1. 2019-02-12. PMID:28706191. |
aldehyde dehydrogenase 1-positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum. |
2019-02-12 |
2023-08-13 |
mouse |
| Peijian Feng, Yulei Chen, Lei Zhang, Cheng-Gen Qian, Xuanzhong Xiao, Xu Han, Qun-Dong She. Near-Infrared Fluorescent Nanoprobes for Revealing the Role of Dopamine in Drug Addiction. ACS applied materials & interfaces. vol 10. issue 5. 2019-02-12. PMID:29308644. |
on the basis of light-induced electron transfer between drns and dopamine and molecular wire effect of the drns, we can track the dynamical change of the neurotransmitter level in the physiological environment and the releasing of the neurotransmitter in living dopaminergic neurons in response to nicotine stimulation. |
2019-02-12 |
2023-08-13 |
mouse |
| Teona Munteanu, Katelyn J Noronha, Amanda C Leung, Simon Pan, Jasmine A Lucas, Tiffany M Schmid. Light-dependent pathways for dopaminergic amacrine cell development and function. eLife. vol 7. 2019-02-12. PMID:30403373. |
dopaminergic amacrine cells (dacs) serve as the sole source of retinal dopamine, and dopamine release in the retina follows a circadian rhythm and is modulated by light exposure. |
2019-02-12 |
2023-08-13 |
mouse |
| Paolo Medrano, Erika Nyhus, Andrew Smolen, Tim Curran, Robert S Ros. Individual differences in EEG correlates of recognition memory due to DAT polymorphisms. Brain and behavior. vol 7. issue 12. 2019-02-11. PMID:29299388. |
although previous research suggests that genetic variation in dopaminergic genes may affect recognition memory, the role dopamine transporter expression may have on the behavioral and eeg correlates of recognition memory has not been well established. |
2019-02-11 |
2023-08-13 |
Not clear |
| Christine M Sandiego, David Matuskey, Meaghan Lavery, Erin McGovern, Yiyun Huang, Nabeel Nabulsi, Jim Ropchan, Marina R Picciotto, Evan D Morris, Sherry A McKee, Kelly P Cosgrov. The Effect of Treatment with Guanfacine, an Alpha2 Adrenergic Agonist, on Dopaminergic Tone in Tobacco Smokers: An [ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 5. 2019-02-06. PMID:28944773. |
the effect of treatment with guanfacine, an alpha2 adrenergic agonist, on dopaminergic tone in tobacco smokers: an [ guanfacine, a noradrenergic alpha2a agonist, reduced tobacco smoking in a 4-week trial and in animal models has been shown to reduce cortical dopamine release, which is critically involved in the reinforcing effect of tobacco smoking. |
2019-02-06 |
2023-08-13 |
Not clear |
| Nausheen Alam, Kulsoom Choudhar. Haloperidol attenuates Methylphenidate and Modafinil induced behavioural sensitization and cognitive enhancement. Metabolic brain disease. vol 33. issue 3. 2019-02-05. PMID:29470766. |
brain dopaminergic system and the involvement of dopamine d |
2019-02-05 |
2023-08-13 |
Not clear |
| G Pagano, T Yousaf, H Wilson, F Niccolini, S Polychronis, K R Chaudhuri, M Politi. Constipation is not associated with dopamine transporter pathology in early drug-naïve patients with Parkinson's disease. European journal of neurology. vol 25. issue 2. 2019-02-04. PMID:29078029. |
the aim of the study was to investigate whether constipation is associated with dopaminergic pathology on dopamine transporter (dat) single-photon emission computed tomography in early drug-naïve patients with pd. |
2019-02-04 |
2023-08-13 |
Not clear |
| Mei Liu, Eun-Joo Shin, Duy-Khanh Dang, Chun-Hui Jin, Phil Ho Lee, Ji Hoon Jeong, Seok-Joo Park, Yong-Sun Kim, Bin Xing, Tao Xin, Guoying Bing, Hyoung-Chun Ki. Trichloroethylene and Parkinson's Disease: Risk Assessment. Molecular neurobiology. vol 55. issue 7. 2019-02-04. PMID:29270919. |
following 8 months of tce treatment, there was a progressive and selective loss of 50% of the dopaminergic neurons in mouse substantia nigra (sn) and about 50% loss of dopamine and 72% loss of 3,4-dihydroxyphenylacetic acid in the striatum, respectively. |
2019-02-04 |
2023-08-13 |
mouse |
| S M Omarova, N V Fedorova, A A Tomskiy, A A Gamaleya, E V Bril', N N Gubareva, A A Poddubskay. [Syndrome dopamine dysregulation and deep brain stimulation of the subthalamic nucleus in Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 117. issue 12. 2019-01-29. PMID:29376980. |
dopamine dysregulation syndrome (dds) is a complication of the dopaminergic therapy in parkinson's disease (pd); it is manifested as a compulsive medication use and may have negative impact on patients' social, psychological, and physical functioning. |
2019-01-29 |
2023-08-13 |
Not clear |
| Annika H Runegaard, Andreas T Sørensen, Ciarán M Fitzpatrick, Søren H Jørgensen, Anders V Petersen, Nikolaj W Hansen, Pia Weikop, Jesper T Andreasen, Jens D Mikkelsen, Jean-Francois Perrier, David Woldbye, Mattias Rickhag, Gitta Wortwein, Ulrik Gethe. Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons. eNeuro. vol 5. issue 3. 2019-01-25. PMID:29938215. |
dopamine plays a key role in the cellular and behavioral responses to drugs of abuse, but the implication of metabotropic regulatory input to dopaminergic neurons on acute drug effects and subsequent drug-related behavior remains unclear. |
2019-01-25 |
2023-08-13 |
mouse |
| Daniel J Kramer, Davide Risso, Polina Kosillo, John Ngai, Helen S Bateu. Combinatorial Expression of eNeuro. vol 5. issue 3. 2019-01-25. PMID:30135866. |
recent studies have shown that dopamine neurons can be subdivided based on gene expression; however, the extent to which genetic markers represent functionally relevant dopaminergic subpopulations has not been fully explored. |
2019-01-25 |
2023-08-13 |
mouse |
| Andrea Cecilia Parrado, Luciana Soledad Salaverry, Franco Mauricio Mangone, Carolina Eugenia Apicella, Teresa Gentile, Andrea Canellada, Estela Beatriz Rey-Roldá. Differential Response of Dopamine Mediated by β-Adrenergic Receptors in Human Keratinocytes and Macrophages: Potential Implication in Wound Healing. Neuroimmunomodulation. vol 24. issue 4-5. 2019-01-21. PMID:29514151. |
we have demonstrated that dopamine modulates cytokine production in keratinocytes via dopaminergic and adrenergic receptors (ars). |
2019-01-21 |
2023-08-13 |
human |
| Marta Brocka, Cornelia Helbing, Daniel Vincenz, Thomas Scherf, Dirk Montag, Jürgen Goldschmidt, Frank Angenstein, Michael Lipper. Contributions of dopaminergic and non-dopaminergic neurons to VTA-stimulation induced neurovascular responses in brain reward circuits. NeuroImage. vol 177. 2019-01-18. PMID:29723641. |
all three stimulation conditions effectively activated the mesolimbic dopaminergic system and triggered dopamine releases into the nacc as measured by in vivo fast-scan cyclic voltammetry. |
2019-01-18 |
2023-08-13 |
human |