| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anne M Landau, Aage Ko Alstrup, Helene Audrain, Steen Jakobsen, Mette Simonsen, Arne Møller, Poul Videbech, Gregers Wegener, Albert Gjedde, Doris J Doude. Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 5. 2019-05-21. PMID:28509598. |
with positron emission tomography (pet), we determined a measure of dopaminergic neurotransmission with the dopamine d1 receptor antagonist [ |
2019-05-21 |
2023-08-13 |
Not clear |
| Yingying Sun, An Ninh Pham, T David Wait. Mechanism Underlying the Effectiveness of Deferiprone in Alleviating Parkinson's Disease Symptoms. ACS chemical neuroscience. vol 9. issue 5. 2019-05-21. PMID:29381045. |
elevation in iron content as well as severe depletion of dopamine (da) as a result of iron-induced loss of dopaminergic neurons has been recognized to accompany the progression of parkinson's disease (pd). |
2019-05-21 |
2023-08-13 |
Not clear |
| Phillip Mackie, Joe Lebowitz, Leila Saadatpour, Emily Nickoloff, Peter Gaskill, Habibeh Khoshboue. The dopamine transporter: An unrecognized nexus for dysfunctional peripheral immunity and signaling in Parkinson's Disease. Brain, behavior, and immunity. vol 70. 2019-05-21. PMID:29551693. |
the dopamine transporter (dat), the main regulator of dopaminergic tone in the cns, is known to exist in lymphocytes and monocytes/macrophages, but little is known about peripheral dat biology or how dat regulates the dopaminergic tone, much less how peripheral dat alters immune function. |
2019-05-21 |
2023-08-13 |
Not clear |
| Andrew Vo, Ken N Seergobin, Penny A MacDonal. Independent effects of age and levodopa on reversal learning in healthy volunteers. Neurobiology of aging. vol 69. 2019-05-21. PMID:29894903. |
it posits that effects of dopaminergic therapy on cognition in parkinson's disease depend on baseline dopamine levels in brain regions that support different functions. |
2019-05-21 |
2023-08-13 |
human |
| Andrew Vo, Ken N Seergobin, Penny A MacDonal. Independent effects of age and levodopa on reversal learning in healthy volunteers. Neurobiology of aging. vol 69. 2019-05-21. PMID:29894903. |
we investigated whether age-related changes in baseline dopamine levels would modulate effects of dopaminergic therapy on reward learning in healthy volunteers. |
2019-05-21 |
2023-08-13 |
human |
| Adam Włodarczyk, Joanna Szarmach, Wiesław Jerzy Cubała, Mariusz Stanisław Wiglus. Benzodiazepines in combination with antipsychotic drugs for schizophrenia: GABA-ergic targeted therapy. Psychiatria Danubina. vol 29. issue Suppl 3. 2019-05-20. PMID:28953788. |
the disruption of gaba-ergic transmission in schizophrenia may induce alternations in dopaminergic neurotransmission providing no inhibitory effect to the central glutamate activity, resulting in the rise of the dopamine levels being associated with psychosis precipitation. |
2019-05-20 |
2023-08-13 |
Not clear |
| Adam Włodarczyk, Joanna Szarmach, Wiesław Jerzy Cubała, Mariusz Stanisław Wiglus. Benzodiazepines in combination with antipsychotic drugs for schizophrenia: GABA-ergic targeted therapy. Psychiatria Danubina. vol 29. issue Suppl 3. 2019-05-20. PMID:28953788. |
benzodiazepines are believed to reduce presynaptic dopamine release at the mesolimbic level and delay postsynaptic adaptation of dopaminergic neurons to antipsychotics potentiating the action of antipsychotics in resistant schizophrenia. |
2019-05-20 |
2023-08-13 |
Not clear |
| G Fond, L Boyer, F Schürhoff, F Berna, O Godin, E Bulzacka, M Andrianarisoa, L Brunel, B Aouizerate, D Capdevielle, I Chereau, N Coulon, T D'Amato, C Dubertret, J Dubreucq, C Faget, C Lançon, S Leignier, J Mallet, D Misdrahi, C Passerieux, R Rey, A Schandrin, M Urbach, P Vidailhet, P M Llorca, M Leboye. Latent toxoplasma infection in real-world schizophrenia: Results from the national FACE-SZ cohort. Schizophrenia research. vol 201. 2019-05-20. PMID:29843964. |
latent toxoplasma infection has been associated with widespread brain immune activation, increased blood brain barrier permeability, neural disruption, increased dopamine release in dopaminergic neurons, with nmda activation and with schizophrenia (sz) onset risk. |
2019-05-20 |
2023-08-13 |
human |
| Lisa-Marie Anders, Sven P Heinrich, Wolf A Lagrèze, Lutz Joachimse. Little effect of 0.01% atropine eye drops as used in myopia prevention on the pattern electroretinogram. Documenta ophthalmologica. Advances in ophthalmology. vol 138. issue 2. 2019-05-17. PMID:30680489. |
the mechanism of action is believed to involve the dopaminergic system of the retina, triggering an increased release of dopamine. |
2019-05-17 |
2023-08-13 |
Not clear |
| Rick C Helmic. The cerebral basis of Parkinsonian tremor: A network perspective. Movement disorders : official journal of the Movement Disorder Society. vol 33. issue 2. 2019-05-16. PMID:29119634. |
in particular, the role of dopamine in tremor has been heavily debated given clinical observations that tremor has a variable response to dopaminergic medication. |
2019-05-16 |
2023-08-13 |
Not clear |
| Daniel Zaldivar, Jozien Goense, Scott C Lowe, Nikos K Logothetis, Stefano Panzer. Dopamine Is Signaled by Mid-frequency Oscillations and Boosts Output Layers Visual Information in Visual Cortex. Current biology : CB. vol 28. issue 2. 2019-05-14. PMID:29307559. |
we recorded the local field potential (lfp) at different depths of primary visual cortex (v1) in anesthetized monkeys (macaca mulatta) during spontaneous activity and during visual stimulation with hollywood movie clips while pharmacologically mimicking dopaminergic neuromodulation by systemic injection of l-dopa (a metabolic precursor of dopamine). |
2019-05-14 |
2023-08-13 |
monkey |
| Phuong-Tram Nguyen, Duy-Khanh Dang, Hai-Quyen Tran, Eun-Joo Shin, Ji Hoon Jeong, Seung-Yeol Nah, Min Chang Cho, Yong Sup Lee, Choon-Gon Jang, Hyoung-Chun Ki. Methiopropamine, a methamphetamine analogue, produces neurotoxicity via dopamine receptors. Chemico-biological interactions. vol 305. 2019-05-10. PMID:30922767. |
moreover, treatment with mpa resulted in significant impairments in dopaminergic parameters [i.e., changes in dopamine level, dopamine turnover rate, tyrosine hydroxylase (th) levels, dopamine transporter (dat) expression, and vesicular monoamine transporter-2 (vmat-2) expression], and in behavioral deficits. |
2019-05-10 |
2023-08-13 |
mouse |
| Phuong-Tram Nguyen, Duy-Khanh Dang, Hai-Quyen Tran, Eun-Joo Shin, Ji Hoon Jeong, Seung-Yeol Nah, Min Chang Cho, Yong Sup Lee, Choon-Gon Jang, Hyoung-Chun Ki. Methiopropamine, a methamphetamine analogue, produces neurotoxicity via dopamine receptors. Chemico-biological interactions. vol 305. 2019-05-10. PMID:30922767. |
therefore, our results suggest that dopamine d1 and d2 receptors simultaneously mediate mpa-induced dopaminergic neurodegeneration in mice via oxidative burdens, microgliosis, and pro-apoptosis. |
2019-05-10 |
2023-08-13 |
mouse |
| Hui-Ju Huang, Yi-Ting Wang, Hui-Ching Lin, Yi-Hsuan Lee, Anya Maan-Yuh Li. Soluble Epoxide Hydrolase Inhibition Attenuates MPTP-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System: Involvement of α-Synuclein Aggregation and ER Stress. Molecular neurobiology. vol 55. issue 1. 2019-05-08. PMID:28822080. |
compared with the mptp-treated wt mice, mptp-induced reductions in striatal dopamine content and nigral tyrosine hydroxylase level (th, a biomarker of dopaminergic neurons) were less significant in the treated seh mice. |
2019-05-08 |
2023-08-13 |
mouse |
| Andrea Varrone, Maria Teresa Pellecchi. SPECT Molecular Imaging in Familial Parkinson's Disease. International review of neurobiology. vol 142. 2019-05-08. PMID:30409254. |
dopamine transporter (dat) imaging with single-photon emission computed tomography (spect) is a diagnostic tool to study the integrity of the dopaminergic system in patients with parkinsonism and uncertain diagnosis. |
2019-05-08 |
2023-08-13 |
human |
| Tetsuya Maeda, Kazuhiro Iwaoka, Yasuo Terayam. Conceptual definition in the metamorphosing Parkinson's disease. Nihon rinsho. Japanese journal of clinical medicine. vol 75. issue 1. 2019-05-08. PMID:30566288. |
the discovery of lewy bodies in the substantia nigra and dopamine deficiency in the nigro- striatal dopaminergic system have confirmed the disease concept of parkinson's disease. |
2019-05-08 |
2023-08-13 |
Not clear |
| Kazushi Takahash. The therapy of the motor symptoms in the advanced stage of Parkinson's disease. Nihon rinsho. Japanese journal of clinical medicine. vol 75. issue 1. 2019-05-08. PMID:30566298. |
levodopa still remains the gold standard for the treatment of motor symptoms of pd in advanced stage, but dopamine agonists, monoamine oxidase b inhibitors and catechol-o-methyltransferase inhibitors have--also been developed to provide more continuous oral delivery of dopaminergic stimulation in order to prevent and improve levodopa-induced motor complications, including wearing off phenomenon and peak-dose dyskinesia. |
2019-05-08 |
2023-08-13 |
Not clear |
| Christopher T Smith, Linh C Dang, Leah L Burgess, Scott F Perkins, M Danica San Juan, Darcy K Smith, Ronald L Cowan, Nam T Le, Robert M Kessler, Gregory R Samanez-Larkin, David H Zal. Lack of consistent sex differences in D-amphetamine-induced dopamine release measured with [ Psychopharmacology. vol 236. issue 2. 2019-05-07. PMID:30350220. |
lack of consistent sex differences in d-amphetamine-induced dopamine release measured with [ sex differences in the dopaminergic response to psychostimulants could have implications for drug abuse risk and other psychopathology involving the dopamine system, but human data are limited and mixed. |
2019-05-07 |
2023-08-13 |
human |
| Mark Z Kos, Jubao Duan, Alan R Sanders, Lucy Blondell, Eugene I Drigalenko, Melanie A Carless, Pablo V Gejman, Harald H H Görin. Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery. Translational psychiatry. vol 8. issue 1. 2019-05-06. PMID:30546022. |
the dopaminergic hypothesis of schizophrenia (sz) postulates that positive symptoms of sz, in particular psychosis, are due to disturbed neurotransmission via the dopamine (da) receptor d2 (drd2). |
2019-05-06 |
2023-08-13 |
Not clear |
| Lisa Y So, Stephanie J Munger, Julie E Mille. Social context-dependent singing alters molecular markers of dopaminergic and glutamatergic signaling in finch basal ganglia Area X. Behavioural brain research. vol 360. 2019-05-02. PMID:30521933. |
social context-dependent singing alters molecular markers of dopaminergic and glutamatergic signaling in finch basal ganglia area x. dopamine (da) is an important neuromodulator of motor control across species. |
2019-05-02 |
2023-08-13 |
Not clear |